NCT06302491
A Study of Safety and Efficiency of AND017 in Patients With β-thalassemia No drug interventions treatment 2 recruiting NCT04411082
A Study of IMR-687 in Subjects With Beta Thalassemia treatment 2 terminated NCT06153784
Thalidomide and Hydroxyurea Combination in β-Thalassemia Patients treatment 2 / 3 completed NCT03183375
The Efficacy and Safety of HYDROXYUREA in Management of Beta Thalassemia Patients in Karachi Pakistan treatment 2 unknown_status NCT05132270
Clinical Experience of Thalidomide in Thalassemic Patients treatment 2 / 3 completed NCT05736419
A Study of Immune Suppression Treatment for People With Sickle Cell Disease or β-Thalassemia Who Are Going to Receive an Allogeneic Hematopoietic Cell Transplantation (HCT) treatment 2 recruiting NCT06298630
Long-term Follow-up Study of BRL-101 for TDT No drug interventions Not Available Not Available not_yet_recruiting NCT05799118
Study of the Role of Genetic Modifiers in Hemoglobinopathies No drug interventions Not Available Not Available recruiting NCT06041620
Safety and Efficacy Evaluation of Autologous CRISPR-Cas12b Edited Hematopoietic Stem Cells No drug interventions treatment Not Available recruiting NCT06314529
Long-term Follow-up Study of BHC001 for TDT No drug interventions Not Available Not Available recruiting NCT03591900
The Use of CGMS to Detect Alterations of Blood Glucose in Thalassemic Patients No drug interventions screening Not Available completed NCT01749540
Study to Evaluate the Safety and Efficacy of Luspatercept (ACE-536) in Participants With Beta-thalassemia (A536-04/MK-6143-002) treatment 2 completed NCT06440603
EKLF Gene Expression in β-thalassemia No drug interventions Not Available Not Available not_yet_recruiting NCT05494333
Correlation Between Pulmonary Functions and Physical Fitness in Children With β-thalassemia No drug interventions Not Available Not Available unknown_status NCT03358498
Quality of Life and Treatment Satisfaction in β-Thalassemia Patients Receiving Deferasirox No drug interventions Not Available Not Available unknown_status NCT05745532
Safety and Efficacy Evaluation of β-globin Restored Autologous Hematopoietic Stem Cells in β-thalassemia Major Patients No drug interventions treatment 0 recruiting NCT05864170
the Safety and Efficacy Evaluation of HGI-001 Injection in Patients With Transfusion-Dependent β-Thalassemia No drug interventions treatment 0 recruiting NCT00560820
Phase I Study to Examine the Effect of Deferasirox on Renal Hemodynamics in β-thalassemia Patients With Transfusional Iron Overload treatment 1 completed NCT05773729
Safety and Efficacy of Gene Modified Autologous Hematopoietic Stem Cells to Treat Transfusion-dependent Beta-thalassemia No drug interventions treatment Not Available recruiting NCT03802201
Study of PTG-300 in Non-Transfusion Dependent and Transfusion-Dependent Beta-Thalassemia Subjects With Chronic Anemia treatment 2 completed NCT04054921
Safety Study for Beta Thalassemia Subjects on PTG-300 treatment 2 completed NCT02268409
Extension Study to Evaluate the Safety and Efficacy of Luspatercept in Participants With β-Thalassemia Previously Enrolled in A536-04 (A536-06/MK-6143-004) treatment 2 completed NCT06465550
A Phase 1 Study of Gene-modified Autologous Hematopoietic Stem Cell (BD211) Treating β-thalassemia Major No drug interventions treatment 1 recruiting NCT03275051
Long-term Follow-up of Subjects Treated With OTL-300 for Transfusion Dependent Beta-thalassemia Study (TIGET-BTHAL) No drug interventions other Not Available active_not_recruiting NCT05357482
Addition of JSP191 (C-kit Antibody) to Nonmyeloablative Hematopoietic Cell Transplantation for Sickle Cell Disease and Beta-Thalassemia treatment 1 / 2 recruiting NCT00001958
Hydroxyurea to Treat Beta-Thalassemia (Cooley's Anemia) treatment 2 completed NCT04929574
Evaluation of Heart Status in Patients of Beta Thalassemia Using Echocardiogram No drug interventions Not Available Not Available recruiting NCT00790127
Phase 1/2 Study of HQK-1001 in Patients With Beta Thalassemia treatment 1 / 2 completed NCT06073860
A Post-Marketing Surveillance Study to Assess Safety of Luspatercept in Korean Patients With Myelodysplastic Syndrome or β-thalassemia Not Available Not Available recruiting NCT01049854
CD34+Selection for Partially Matched Family or Matched Unrelated Adult Donor Transplant treatment 2 completed NCT00408447
Stem Cell Transplant in Sickle Cell Disease and Thalassemia treatment 2 active_not_recruiting NCT04917978
Association of Hb F Level With Clinical Severity of Beta Thalassemia No drug interventions Not Available Not Available recruiting NCT04918056
Genetic Variants Affecting the Clinical Severity of Beta Thalassemia No drug interventions Not Available Not Available unknown_status NCT00159042
Genetic Factors Affecting the Severity of Beta Thalassemia No drug interventions Not Available Not Available completed NCT00005934
5-Azacytidine and Phenylbutyrate to Treat Severe Thalassemia treatment 2 completed NCT01931644
At-Home Research Study for Patients With Autoimmune, Inflammatory, Genetic, Hematological, Infectious, Neurological, CNS, Oncological, Respiratory, Metabolic Conditions No drug interventions Not Available Not Available completed NCT02597595
Effects of Spirulina on Cardiac Functions in Children With Beta Thalassemia Major No drug interventions prevention Not Available completed NCT06647979
Hematopoietic Stem Cell BCL11A Enhancer Gene Editing for Severe Β-Hemoglobinopathies No drug interventions treatment 1 not_yet_recruiting NCT06308159
An Open-label Study of a Gene Therapy Product (Vebeglogene Autotemcel) in Transfusion Dependent Beta-Thalassemia No drug interventions treatment 1 / 2 recruiting NCT03655678
A Safety and Efficacy Study Evaluating CTX001 in Subjects With Transfusion-Dependent β-Thalassemia treatment 2 / 3 active_not_recruiting NCT06364774
ALS20-101 Lentiviral Gene Therapy for Beta Thalassemia No drug interventions treatment 1 / 2 recruiting NCT05567458
A Study to Evaluate Luspatercept (ACE-536) in Chinese Participants Who Require Regular Red Blood Cell Transfusions Due to Beta (β)-Thalassemia. treatment 2 active_not_recruiting NCT06271512
A Study of Participants with Β-Thalassemia Treated with Betibeglogene Autotemcel No drug interventions Not Available Not Available recruiting NCT03462784
Complications in Children With B- Thalassemia Major No drug interventions Not Available Not Available unknown_status NCT02274233
Safety and Pharmacokinetic Study of Escalating Doses of SP-420, an Iron Chelator, in Patients With β-Thalassemia treatment 1 terminated NCT02453477
Gene Therapy for Transfusion Dependent Beta-thalassemia No drug interventions treatment 1 / 2 unknown_status NCT03894605
Dermatological Abnormalities in Beta-thalassemia Major No drug interventions Not Available Not Available unknown_status NCT03961828
Hyalornic Acid Level in β-Thalassemic Children Treated for Hepatitis C Virus treatment 4 completed NCT00171171
A Study of Long-term Treatment With Deferasirox in Patients With Beta-thalassemia and Transfusional Hemosiderosis treatment 3 completed NCT03877809
Testing SIROLIMUS in Beta-thalassemia Transfusion Dependent Patients treatment 2 completed NCT03822585
Detection Of β-thalassemia Carriers In Assiut No drug interventions prevention Not Available unknown_status NCT01927913
Treatment of Iron Overload Requiring Chelation Therapy treatment 2 withdrawn NCT01186419
Safety and Pharmacodynamic Study of an Oral Iron Chelator Given for 6 Months to Patients With Iron Overload treatment 2 completed NCT03271541
A Study of Bitopertin (RO4917838) in Adults With Non-Transfusion-Dependent (NTD) Beta-Thalassemia treatment 2 completed NCT05506358
Evaluation of Low-cost Techniques for Detecting Sickle Cell Disease and β-thalassemia in Nepal and Canada No drug interventions diagnostic Not Available completed NCT05635266
Tissue Repository Providing Annotated Biospecimens for Approved Investigator-directed Biomedical Research Initiatives No drug interventions Not Available Not Available recruiting NCT02474420
Amlodipine as Adjuvant Treatment to Iron Chelation for Prevention of Cardiac Iron Overload in Thalassemia Patients treatment Not Available unknown_status NCT04064060
A Study to Evaluate Long-term Safety in Participants Who Have Participated in Other Luspatercept (ACE-536) Clinical Trials treatment 3 recruiting NCT00029380
Cord Blood Transplantation for Sickle Cell Anemia and Thalassemia treatment 2 completed NCT04208529
A Long-term Follow-up Study in Participants Who Received CTX001 other 3 enrolling_by_invitation NCT06065189
Base-edited Autologous Hematopoietic Stem Cell Transplantation in Treating Patients With β-thalassemia Major No drug interventions treatment 0 recruiting NCT02626689
To Document the Burden of Illness on the Quality of Life and the Impact on Healthcare Utilization in (Beta) β-thalassemia Subjects Who Are Transfusion Dependent (TD) and Non-transfusion Dependent (NTD) Receiving Standard of Care No drug interventions Not Available Not Available completed NCT04947540
Iron Status in BTM With Blood Transfusion No drug interventions Not Available Not Available unknown_status NCT01419704
Phase I/II Pilot Study of Mixed Chimerism to Treat Hemoglobinopathies No drug interventions treatment 1 / 2 withdrawn NCT04364269
Safety, Tolerability, Pharmacokinetics (PK), Pharmacodynamics (PD) and Preliminary Efficacy of VIT-2763 in β-thalassaemia treatment 2 completed NCT06539169
FLOWER: Following Longitudinal Outcomes With Epidemiology for Rare Diseases No drug interventions Not Available Not Available recruiting NCT05577312
Safety and Efficacy Evaluation of BRL-101 in Subjects With Transfusion-Dependent β-Thalassemia No drug interventions treatment 1 enrolling_by_invitation NCT00000595
Evaluation of Subcutaneous Desferrioxamine as Treatment for Transfusional Hemochromatosis treatment 2 completed NCT00061750
Safety & Efficacy of ICL670 vs. Deferoxamine in Beta-thalassemia Patients With Iron Overload Due to Blood Transfusions treatment 3 completed NCT03655223
Early Check: Expanded Screening in Newborns No drug interventions Not Available Not Available enrolling_by_invitation NCT03728543
the Efficacy and Safety of Sugammadex in Children 0-2 Years Old treatment 2 / 3 unknown_status NCT06328764
CS-101 in Patients With β-thalassemia No drug interventions treatment 0 enrolling_by_invitation NCT02906202
A Study Evaluating the Efficacy and Safety of the LentiGlobin® BB305 Drug Product in Participants With Transfusion-Dependent β-Thalassemia, Who do Not Have a β0/β0 Genotype No drug interventions treatment 3 completed NCT02604433
An Efficacy and Safety Study of Luspatercept (ACE-536) Versus Placebo in Adults Who Require Regular Red Blood Cell Transfusions Due to Beta (β) Thalassemia treatment 3 completed NCT03381833
A Study With LJPC-401 for the Treatment of Myocardial Iron Overload in Patients With Transfusion-Dependent Beta Thalassemia treatment 2 terminated NCT00103753
Combined Chelation Treatment With Deferiprone and Deferoxamine in Thalassemia Major treatment 4 unknown_status NCT03222453
Thalassemia Treatment Based on the Stem Cell Technology No drug interventions treatment Not Available unknown_status NCT05370677
The Prevelence of IVS 1-6 (T-C) [HBB:c.92 +6 T-C] Gene Mutation in Suspected Cases of β Thalassemia in Assiut University Hospitals No drug interventions Not Available Not Available not_yet_recruiting NCT03889977
Resistance Exercise on Postprandial Hyperglycemia in Patients With B-thalassemia Exhibiting Resistance to Insulin No drug interventions treatment Not Available completed NCT06512298
Plasticizer Exposure and Its Consequences on Health No drug interventions Not Available Not Available not_yet_recruiting NCT01996683
Efficacy and Safety of Efficacy and Safety of Continued Iron Chelation Therapy In Poly-transfused Thalassemia Patients With Low Serum Ferritin (< 500 ng/ml) treatment Not Available unknown_status NCT00733811
Efficacy Study of the Use of Sequential DFP-DFO Versus DFP treatment 4 completed NCT01016093
Zoledronic Acid for the Prevention of Bone Loss Post-bone Marrow Transplantation for Thalassemia Major Patients treatment 2 / 3 unknown_status NCT00000588
Chelation Therapy of Iron Overload With Pyridoxal Isonicotinoyl Hydrazone No drug interventions treatment 2 completed NCT05133388
The Prevelence of HBB c.93-21 G-A in β Thalassemia Patients No drug interventions Not Available Not Available recruiting NCT03207009
A Study Evaluating the Efficacy and Safety of the LentiGlobin® BB305 Drug Product in Participants With Transfusion-Dependent β-Thalassemia No drug interventions treatment 3 completed NCT01206075
Evaluating the Safety and Effectiveness of Mozobil Mobilization in Adults With Beta-Thalassemia Major treatment Not Available completed NCT00115349
Combination Therapy Compared With Single-Drug Therapy in Patients With Cardiac Diseases treatment 2 terminated NCT04219449
Thrombophilia In Beta Thalassemia No drug interventions Not Available Not Available not_yet_recruiting NCT01039636
Safety and Pharmacokinetic Study of Escalating Multiple Doses of an Iron Chelator in Patients With Iron Overload treatment 1 completed NCT00006136
Phase II Study of Arginine Butyrate With or Without Epoetin Alfa in Patients With Thalassemia Intermedia treatment 2 completed NCT00564941
Evaluating the Efficacy of Deferasirox in Transfusion Dependent Chronic Anaemias (Myelodysplastic Syndrome, Beta-thalassaemia Patients) With Chronic Iron Overload treatment 4 completed NCT04143724
Study of Safety & PK of Luspatercept (ACE-536) in Pediatric Participants With Beta (β)-Thalassemia treatment 2 recruiting NCT06479616
A Long-term Follow-up Study in Participants Who Received CS-101 No drug interventions other Not Available recruiting NCT04067258
Choroidal Thickness in Beta-thalassemia Patients No drug interventions Not Available Not Available completed NCT04938635
Efficacy and Safety Study of Multiple Doses of VIT-2763 in Adults With Transfusion-dependent Beta-thalassemia treatment 2 withdrawn NCT00061763
Study of Deferasirox in Iron Overload From Beta-thalassemia Unable to be Treated With Deferoxamine or Chronic Anemias treatment 2 completed NCT05477563
Evaluation of Efficacy and Safety of a Single Dose of CTX001 in Participants With Transfusion-Dependent β-Thalassemia and Severe Sickle Cell Disease treatment 3 recruiting NCT05469230
Assessment of Cognitive Function, Fatigue and Health Related Quality of Life in Children With Beta Thalassemia No drug interventions Not Available Not Available completed NCT02950857
A Study of EPEG in Beta Thalassemia Patients No drug interventions treatment 1 completed NCT06568926
Adherence of Beta Thalssemia Patients to Oral Chelation Therapy No drug interventions health_services_research Not Available recruiting NCT04099966
AlloSCT for Malignant and Non-malignant Hematologic Diseases Utilizing Alpha/Beta T Cell and CD19+ B Cell Depletion treatment 2 recruiting NCT06024876
A Clinical Study Evaluating the Safety and Efficacy of CS-101 in Treating Subjects With β-thalassemia No drug interventions treatment 0 active_not_recruiting NCT00447694
Cardiac T2* in Beta-thalassemia Patients on Deferasirox Treatment treatment 2 completed NCT00336362
Evaluating the Safety of G-CSF Mobilization in Individuals With Beta Thalassemia Major treatment Not Available completed NCT00069862
Iron Balance Study of DFO and GT56-252 in Patients With Transfusional Iron Overload Secondary to Beta-Thalassemia treatment 1 / 2 completed NCT04973280
Study to Evaluate Additional Risk Minimisation Measures (aRMMs) for REBLOZYL Among Healthcare Professionals (HCPs) No drug interventions Not Available Not Available completed NCT03351829
Gene Therapy of Beta Thalassemia Using a Self-inactivating Lentiviral Vector No drug interventions treatment Not Available unknown_status NCT03801889
SP-420 in Subjects With Transfusion-dependent Beta-Thalassemia or Other Rare Anemias treatment 2 withdrawn NCT06239389
Comparison Of Efficacy And Safety Of Thalidomide Vs Hydroxyurea In Thalassemia Patients: A Single-Centre Pilot Study. treatment 2 completed NCT06490601
Long Term Beta Thalassemia Treatment: Findings From The Extension Period treatment 2 active_not_recruiting NCT01092169
Prevalence Of Microalbuminuria Among Children Suffering From Sickle Cell Nephropathy and Sickle Cell/Beta-Thalassemia No drug interventions Not Available Not Available unknown_status NCT06509581
Vitamin E Supplementation for Children With Transfusion Dependent Beta Thalassemia on Different Iron Chelation Regimen No drug interventions treatment Not Available completed NCT05356195
Evaluation of Safety and Efficacy of CTX001 in Pediatric Participants With Transfusion-Dependent β-Thalassemia (TDT) treatment 3 recruiting NCT04247750
Testing SIROLIMUS in Beta-thalassemia Transfusion Dependent Patients (THALA-RAP) treatment 2 unknown_status NCT00000623
Thalassemia (Cooley's Anemia) Clinical Research Network (TCRN) Not Available Not Available completed NCT01363908
Safety, Efficacy and Pharmacokinetics of an Oral Iron Chelator Given for a Year to Pediatric Patients With Iron Overload treatment 2 terminated NCT05105659
Assessment of Cognitive Functions, Psychological Symptoms, and Quality of Life Among B Thalassemia Patients and Their Clinical Correlates. No drug interventions Not Available Not Available unknown_status NCT06377865
Thyroid Function , HbA1c in Relation to Ferritin Level in Adullt Patient e B Thalassemia No drug interventions Not Available Not Available not_yet_recruiting NCT01863173
Effect of Metoprolol on Thalassemia Cardiomyopathy treatment 2 / 3 completed