NCT04328727
Combination of Eltrombopag With Immunosuppressive Therapy in East-Asian Patients With Severe Aplastic Anemia treatment 2 active_not_recruiting NCT01900119
A Description of Bacteria in the Mouths of Patients With Severe Aplastic Anemia No drug interventions Not Available Not Available completed NCT05323617
Efficacy of Romiplostim in Treatment of SAA in Adults Previously Untreated With or Refractory to Immunosuppressive Therapy treatment 2 withdrawn NCT01891994
Extended Dosing With Eltrombopag for Severe Aplastic Anemia treatment 2 completed NCT03520647
Haplo-identical Transplantation for Severe Aplastic Anemia, Hypo-plastic MDS and PNH Using Peripheral Blood Stem Cells and Post-transplant Cyclophosphamide for GVHD Prophylaxis treatment 2 recruiting NCT00001626
Comparing Therapies for the Treatment of Severe Aplastic Anemia treatment 2 completed NCT04409080
REGN7257 in Adult Patients With Severe Aplastic Anemia That Is Refractory to or Relapsed on Immunosuppressive Therapy No drug interventions treatment 1 / 2 recruiting NCT00604201
Stem Cell Transplant Using Peripheral and Cord Blood Stem Cells to Treat Severe Aplastic Anemia and Myelodysplastic Syndrome treatment 2 completed NCT05012111
Natural History of Acquired and Inherited Bone Marrow Failure Syndromes No drug interventions Not Available Not Available recruiting NCT01174108
Allogeneic Hematopoietic Stem Cell Transplantation for Severe Aplastic Anemia and Other Bone Marrow Failure Syndromes Using G-CSF Mobilized CD34+ Selected Hematopoietic Precursor Cells Co-Infused With a Reduced Dose of Non-Mobilized Donor T-cells No drug interventions treatment 2 recruiting NCT06622694
CD7 CAR T Cells (RD13-02) in the Treatment of Relapsed/Refractory Severe Aplastic Anemia No drug interventions treatment 1 not_yet_recruiting NCT05975996
Cyclophosphamide Added to Standard Immunosuppressive Therapy With Herombopag as Front-line Therapy in Patients With Severe Aplastic Anemia treatment 2 active_not_recruiting NCT05998408
JAK1/2 Inhibitor Ruxolitinib for Relapsed/Refractory Immune Bone Marrow Failure treatment 1 / 2 recruiting NCT03836690
Transfer of Effector Memory T Cells (Tem) Following Allogeneic Stem Cell Transplantation No drug interventions treatment 1 unknown_status NCT05236764
Haploidentical Hematopoietic Cell Transplantation Using TCR Alpha/Beta and CD19 Depletion No drug interventions treatment Not Available recruiting NCT00001964
Combination Therapy of Severe Aplastic Anemia treatment 2 completed NCT00004143
Allogeneic Mixed Chimerism Stem Cell Transplant Using Campath for Hemoglobinopathies & Bone Marrow Failure Syndromes treatment 2 completed NCT01319851
Alefacept and Allogeneic Hematopoietic Stem Cell Transplantation treatment Not Available terminated NCT01768845
Unrelated Umbilical Cord Blood (UBC)Transplantation No drug interventions treatment Not Available completed NCT01351545
A Multicenter Access and Distribution Protocol for Unlicensed Cryopreserved Cord Blood Units (CBUs) No drug interventions Not Available Not Available recruiting NCT06412497
MT2023-20: Hematopoietic Cell Transplant With Reduced Intensity Conditioning and Post-transplant Cyclophosphamide for Severe Aplastic Anemia and Other Forms of Acquired Bone Marrow Failure. treatment 2 recruiting NCT03246178
Haploidentical Transplantation in Severe Aplastic Anemia No drug interventions treatment Not Available unknown_status NCT00212407
New York Blood Center National Cord Blood Program No drug interventions treatment 0 terminated NCT03579875
Alpha/Beta TCD HCT in Patients With Inherited BMF Disorders treatment 2 recruiting NCT02407470
Safety and Efficacy of Patient's Own AD-MSC and AD-HSC Transplantation in Patients With Severe Aplastic Anemia No drug interventions treatment 1 / 2 unknown_status NCT03557099
A Study to Evaluate the Safety and Efficacy of Hetrombopag Olamine in Severe Aplastic Anemia (SAA) Patient No drug interventions treatment 1 / 2 completed NCT01383434
Bone Marrow Transplant Trial for Patients With Refractory Severe Aplastic Anemia No drug interventions treatment 2 terminated NCT02845596
Unrelated Donor Transplant Versus Immune Therapy in Pediatric Severe Aplastic Anemia other Not Available active_not_recruiting NCT01364363
Unrelated Donor Stem Cell Transplantation No drug interventions treatment Not Available completed NCT03333486
Fludarabine Phosphate, Cyclophosphamide, Total Body Irradiation, and Donor Stem Cell Transplant in Treating Patients With Blood Cancer treatment 2 active_not_recruiting NCT05433922
Efficacy and Safety of CSA and Avatrombopag for the Treatment of SAA in the Elderly treatment Not Available recruiting NCT00358657
Fludarabine Phosphate, Cyclophosphamide, and Total-Body Irradiation Followed by Donor Bone Marrow Transplant and Cyclophosphamide, Mycophenolate Mofetil, Tacrolimus, and Sirolimus in Treating Patients With Primary Immunodeficiency Disorders or Noncancerous Inherited Disorders treatment 2 terminated NCT05600426
A Trial Comparing Unrelated Donor BMT With IST for Pediatric and Young Adult Patients With Severe Aplastic Anemia (TransIT, BMT CTN 2202) treatment 3 recruiting NCT04304820
Early Initiation of Oral Therapy With Cyclosporine and Eltrombopag for Treatment Naive Severe Aplastic Anemia (SAA) treatment 2 recruiting NCT00590460
Antibody Conditioning Regimen For Allogeneic Donor Stem Cell Transplantation Of Patients With Fanconi Anemia treatment 1 / 2 terminated NCT06279494
Sirolimus+Abatacept+Mycophenolate Mofetil for Prophylaxis of aGVHD in Patients Receiving Haplo-HSCT Who Are Intolerant to Calcineurin Inhibitors prevention 1 / 2 not_yet_recruiting NCT06069180
The Optimization of Conditioning Regimen for HLA Matched HSCT in SAA treatment 4 recruiting NCT02828592
Haploidentical Bone Marrow Transplant With Post-Transplant Cyclophosphamide for Patients With Severe Aplastic Anemia treatment 2 recruiting NCT02918292
Optimizing Haploidentical Aplastic Anemia Transplantation (BMT CTN 1502) treatment 2 completed NCT01966367
CD34+ (Non-Malignant) Stem Cell Selection for Patients Receiving Allogeneic Stem Cell Transplantation No drug interventions treatment 1 / 2 active_not_recruiting NCT04436367
Retrospective Study of Patients With Severe Aplastic Anemia Who Developed High Risk Clonal Evolution With Chromosome 7 Abnormalities After Immunosuppressive Therapy No drug interventions Not Available Not Available completed NCT01703169
Efficacy and Safety of Eltrombopag In Patients With Severe and Very Severe Aplastic Anemia treatment 2 completed NCT04356469
TCR Alpha Beta T-cell Depleted Haploidentical HCT in the Treatment of Non-Malignant Hematological Disorders in Children treatment 2 recruiting NCT01586455
Human Placental-Derived Stem Cell Transplantation No drug interventions treatment 1 completed NCT01129323
Reduced-Intensity Preparative Regimen for Allogeneic Stem Cell Transplantation in Patients With Severe Aplastic Anemia treatment Not Available withdrawn NCT05419843
Up-front Matched Unrelated Donor Transplantation in Pediatric Patients With Idiopathic Aplastic Anemia No drug interventions other 2 not_yet_recruiting NCT05531279
A Study of PEG-rhG-CSF and rhG-CSF Used for Aplastic Anemia Granulocyte Deficiency No drug interventions treatment Not Available recruiting NCT02065154
Post Transplant Cyclophosphamide (Cytoxan) for GvHD Prophylaxis prevention 2 completed NCT02099747
hATG+CsA vs hATG+CsA+Eltrombopag for SAA treatment 3 completed NCT02998645
Eltrombopag Combined With Cyclosporine as First Line Therapy in Patients With Severe Acquired Aplastic Anemia treatment 2 completed NCT02833805
NMA Haplo or MUD BMT for Newly Diagnosed Severe Aplastic Anemia treatment 2 completed NCT03192397
Chemotherapy, Total Body Irradiation, and Post-Transplant Cyclophosphamide in Reducing Rates of Graft Versus Host Disease in Patients With Hematologic Malignancies Undergoing Donor Stem Cell Transplant treatment 1 / 2 active_not_recruiting NCT01193283
Cyclophosphamide Plus Cyclosporine in Treatment-Naive Severe Aplastic Anemia treatment 1 / 2 completed NCT03173937
Unrelated Umbilical Cord Blood Transplantation for Severe Aplastic Anemia and Hypo-plastic MDS Using CordIn(TM), Umbilical Cord Blood-Derived Ex Vivo Expanded Stem and Progenitor Cells to Expedite Engraftment and Improve Transplant Outcome treatment 1 / 2 recruiting NCT00516152
Phase II Study Evaluating Busulfan and Fludarabine as Preparative Therapy in Adults With Hematopoietic Disorders Undergoing MUD SCT treatment 2 completed NCT06039436
Conditioning Regimen Containing Low Dose ATG for The Treatment of Acquired SAA Receiving sUCBT Not Available Not Available recruiting NCT06517641
Clinical Trial of Upfront Haploidentical or Unrelated Donor BMT to Restore Normal Hematopoiesis in Aplastic Anemia No drug interventions treatment 2 not_yet_recruiting NCT01187017
A Pilot Study of Fludarabine Plus Cyclophosphamide in Refractory Severe Aplastic Anemia treatment 1 / 2 completed NCT02745717
The Efficacy of Immunosuppressive Therapy Combined With Cord Blood Transfusion in Treatment of Severe Aplastic Anemia treatment 4 completed NCT05720234
Avatrombopag Combined With IST as First-line Treatment for SAA treatment 2 recruiting NCT03295058
Peripheral Blood Allogenic Stem Cell Transplantation Using Non-anti Thymocyte Globulin Regimens in Severe Aplastic Anemia Patients No drug interventions treatment 2 / 3 unknown_status NCT04099966
AlloSCT for Malignant and Non-malignant Hematologic Diseases Utilizing Alpha/Beta T Cell and CD19+ B Cell Depletion treatment 2 recruiting NCT02979873
Sirolimus (Rapamune ) for Relapse Prevention in People With Severe Aplastic Anemia Responsive to Immunosuppressive Therapy treatment 2 recruiting NCT02247973
Mesenchymal Stem Cells Co-transplantation in Alternative Donor Transplantation of Severe Aplastic Anemia. treatment 2 unknown_status NCT06254560
Rituximab for Serious Aplastic Anemia With Platelet Transfusion Refractoriness treatment 2 recruiting NCT00061360
Improving Immunosuppressive Treatment for Patients With Severe Aplastic Anemia treatment 2 completed NCT06378060
Clinical Study on Modified Allogeneic Hematopoietic Stem Cell Transplantation Regimen for Severe Aplastic Anemia No drug interventions treatment 2 recruiting NCT04436380
Retrospective Study of Patients With Severe Aplastic Anemia Who Relapsed After Immunosuppressive Therapy No drug interventions Not Available Not Available completed NCT03825744
Hetrombopag or Placebo in Treatment-Naive Severe Aplastic Anemia No drug interventions treatment 3 active_not_recruiting NCT01623167
Eltrombopag With Standard Immunosuppression for Severe Aplastic Anemia treatment 1 / 2 recruiting NCT02224872
Transplantation of Partially Mismatched Related or Matched Unrelated Bone Marrow for Patients With Refractory Severe Aplastic Anemia treatment 2 completed NCT01997372
Different Doses of Anti-thymocyte Globin to Treat Child Severe Aplastic Anemia No drug interventions treatment 4 unknown_status NCT05049668
RACE 2: a Long Term Follow-up of Patients Participating in the RACE Trial Not Available Not Available enrolling_by_invitation NCT01472055
Pharmacokinetic Study of Fludarabine in Pediatric Hematopoietic Stem Cell Transplantation treatment 2 unknown_status NCT01917708
Bone Marrow Transplant With Abatacept for Non-Malignant Diseases supportive_care 1 completed NCT01553461
Transplants With Unlicensed Preserved Cord Blood No drug interventions treatment 1 / 2 recruiting