Aminoglycoside Antibacterials

Name
Aminoglycoside Antibacterials
Accession Number
DBCAT000853  (DBCAT002397)
Description

A category of amino glycoside antibacterials. Must have an amino group attached to a glycoside and have antibacterial effects. Relation to Streptomyces spp. is considered important, but is not enough alone to allow for categorization here. Structurally, it must be an aminoglycoside. It must have antibacterial properties. It potentially came from a Streptomycin spp.

Drugs
DrugDrug Description
AklavineAklavine is under investigation in clinical trial NCT03026842 (Decitabine Versus Conventional Chemotherapy for Maintenance Therapy of Acute Myeloid Leukemia With T(8;21)).
AmikacinAn aminoglycoside used to treat infections caused by more resistant strains of Gram negative bacteria and some Gram positive bacteria.
ApramycinAn aminoglycoside antibiotic for veterinary use that is used to treat infections in animals.
ArbekacinArbekacin is used for the short term treatment of multi-resistant bacterial infections, such as methicillin-resistant Staphylococcus aureus (MRSA).
BekanamycinAn aminoglycoside antibiotic indicated in the treatment of eye infections.
BerubicinNot Annotated
BluensomycinBluensomycin is a small molecule drug. The usage of the INN stem '-mycin' in the name indicates that Bluensomycin is a antibiotic, produced by Streptomyces strain. Bluensomycin has a monoisotopic...
CapreomycinAn aminoglycoside antibiotic used as an adjunct drug in tuberculosis.
ColistinA polymyxin antibiotic used to treat bacterial infections caused by susceptible Gram negative bacteria.
DibekacinDibekacin is an aminoglycoside antibiotic marketed in Japan .
DihydrostreptomycinDihydrostreptomycin is an aminoglycoside antibiotic. In humans, the use of dihydrostreptomycin has been associated with ototoxicity. The FDA withdrew its approval for the use of all drug products containing dihydrostreptomycin...
FramycetinAn aminoglycoside antibiotic used in various formulations and combinations with other agents to treat hemorrhoids, eye and ear infections, and to reduce nasal carriage of staphylococcus.
GeneticinGeneticin (also known as G418) is an aminoglycoside antibiotic similar in structure to gentamicin B1, produced by Micromonospora rhodorangea. Geneticin blocks polypeptide synthesis by inhibiting the elongation step in both...
GentamicinAn aminoglycoside used to treat a wide variety of aerobic infections in the body.
Gentamicin C1aNot Available
Gentamicin C2Not Annotated
Hygromycin BHygromycin B is an aminoglycoside antibiotic produced by the bacterium Streptomyces hygroscopicus which kills bacteria, fungi and higher eukaryotic cells by inhibiting protein synthesis.
IsepamicinNot Annotated
KanamycinAn aminoglycoside antibiotic agent used in the treatment of various infections caused by susceptible bacteria.
LadirubicinLadirubicin is a small molecule drug. Ladirubicin has a monoisotopic molecular weight of 601.16 Da.
MicronomicinMicronomicin is an aminoglycoside antibiotic which is marketed in Japan, and sold under the brand names Sagamicin and Luxomicina.
Nanoparticle EpirubicinNanoparticle Epirubicin is under investigation in clinical trial NCT03168061 (Dose-escalation and Expansion Trial of NC-6300 in Patients With Advanced Solid Tumors or Soft Tissue Sarcoma). It is a novel epirubicin...
NC-6300NC-6300, also known as K-912, is a novel epirubicin drug-conjugated polymeric micelle.
NeamineNot Available
NeomycinAn aminoglycoside antibiotic agent used orally and topically to treat a wide variety of infections in the body.
NetilmicinAn aminoglycoside used to treat a wide variety of infections in the body.
NogalamycinNogalamycin is a small molecule drug. The usage of the INN stem '-mycin' in the name indicates that Nogalamycin is a antibiotic, produced by Streptomyces strain. Nogalamycin has a monoisotopic...
ParomomycinAn aminoglycoside antibiotic used in the treatment of acute and chronic intestinal amebiasis, and as an adjunct for the management of hepatic coma.
PlazomicinAn aminoglycoside antibiotic used to treat complicated urinary tract infections.
PropikacinPropikacin is a small molecule drug. Propikacin has a monoisotopic molecular weight of 557.29 Da.
PuromycinPuromycin is an antibiotic that prevents bacterial protein translation. It is utilized as a selective agent in laboratory cell cultures. Puromycin is toxic to both prokaryotic and eukaryotic cells, resulting...
RibostamycinA broad spectrum aminoglycoside antibiotic on the list of WHO critical antimicrobials for human medicine.
SisomicinSisomicin has been used in trials studying the treatment of Pyoderma.
SteffimycinSteffimycin is a small molecule drug. The usage of the INN stem '-mycin' in the name indicates that Steffimycin is a antibiotic, produced by Streptomyces strain. Steffimycin has a monoisotopic...
StreptomycinAn aminoglycoside antibiotic indicated to treat multi-drug resistant mycobacterium tuberculosis and various non-tuberculosis infections.
TobramycinAn aminoglycoside antibiotic used to treat cystic fibrosis-associated bacterial, lower respiratory tract, urinary tract, eye, skin, bone, and skin structure infections.