Allergies

Also known as: Allergy / Hypersensitivity NOS / Hypersensitivity reaction / Allergy NOS / Hypersensitivity reaction (NOS) / Reaction hypersensitivity (NOS) / Allergic reaction / Hypersensitivity / Allergic reaction NOS / Reaction allergic (NOS) / Allergic reaction (NOS) / HYSN / Hypersensitivity symptom

DrugDrug NameDrug Description
DB00316AcetaminophenAn analgesic drug used alone or in combination with opioids for pain management, and as an antipyretic agent.
DB00062Albumin humanA purified form of human serum albumin used to replace lost albumin in patients with hypoalbuminemia, to treat hypovolemia and ascites, and as a part of some diagnostic imaging kits.
DB00835BrompheniramineA histamine H1 antagonist used to treat coughs, upper respiratory symptoms, and nasal congestion associated with allergies and the common cold.
DB00354BuclizineFor prevention and treatment of nausea, vomiting, and dizziness associated with motion sickness and vertigo (dizziness caused by other medical problems).
DB01222BudesonideA corticosteroid used to treat Crohn's disease, asthma, COPD, hay fever and allergies, and ulcerative colitis.
DB08936ChlorcyclizineChlorcyclizine is a first generation phenylpiperazine class antihistamine used to treat urticaria, rhinitis, pruritus, and other allergy symptoms. Chlorcyclizine also has some local anesthetic, anticholinergic, and antiserotonergic properties, and can...
DB01243ChloroxineAn antibacterial agent used for the treatment of dandruff and mild to moderately severe seborrheic dermatitis of the scalp.
DB01114ChlorpheniramineA histamine-H1 receptor antagonist indicated for the management of symptoms associated with upper respiratory allergies.
DB14006Choline salicylateThe oral gel is indicated for the relief of pain and discomfort of common mouth ulcers, cold sores, denture sore spots, infant teething and mouth ulcers, and sore spots due...
DB09555Dexchlorpheniramine maleateA first generation antihistamine used to treat allergic and vasomotor rhinitis, allergic conjunctivitis, and mild urticaria and angioedema.
DB08801DimetindeneIndicated as symptomatic treatment of allergic reactions: urticaria, allergies of the upper respiratory tract such as hey fever and perennial rhinitis, food and drug allergies; pruritus of various origins, except...
DB01075DiphenhydramineA H1 receptor antihistamine used in the treatment of seasonal allergies, and various allergic reactions including sneezing, runny nose, itchy/watery eyes, itching of nose or throat, pruritus, urticaria, insect bites/stings, and allergic rashes.
DB13808MebhydrolinNot Annotated
DB06691MepyramineAn antihistamine agent used for the symptomatic treatment of allergy, hypersensitivity reactions, and pruritic skin disorders.
DB01069PromethazineA first-generation antihistamine used for the treatment of allergic conditions, nausea and vomiting, and motion sickness.
DB06764TetryzolineAn alpha-adrenergic agonist used in the temporary symptomatic relief of discomfort and redness of the eyes due to minor irritations.
DB11235ThonzylamineThozylamine is indicated for use in the symptomatic control of allergic rhinitis or other upper respiratory allergic symptoms [FDA Label]. It is typically a part of combination over the counter...
DB00427TriprolidineA sedating antihistamine combined with pseudoephedrine and guaifenesin in various types of cold and allergy medications to relieve allergy symptoms, hay fever and common cold symptoms, and to aid in sleep.
DrugDrug NameTargetType
DB00316AcetaminophenProstaglandin G/H synthase 1target
DB00316AcetaminophenProstaglandin G/H synthase 2target
DB00316AcetaminophenCytochrome P450 1A2enzyme
DB00316AcetaminophenCytochrome P450 2E1enzyme
DB00316AcetaminophenP-glycoprotein 1transporter
DB00316AcetaminophenCytochrome P450 2D6enzyme
DB00316AcetaminophenCytochrome P450 2A6enzyme
DB00316AcetaminophenCytochrome P450 3A4enzyme
DB00316AcetaminophenUDP-glucuronosyltransferase 1-1enzyme
DB00316AcetaminophenUDP-glucuronosyltransferase 1-6enzyme
DB00316AcetaminophenUDP-glucuronosyltransferase 1-9enzyme
DB00316AcetaminophenUDP-glucuronosyltransferase 2B15enzyme
DB00316AcetaminophenSulfotransferase 1A1enzyme
DB00316AcetaminophenSulfotransferase 1A3/1A4enzyme
DB00316AcetaminophenArylamine N-acetyltransferase 2enzyme
DB00316AcetaminophenProstaglandin E synthase 3target
DB00316AcetaminophenTransient receptor potential cation channel subfamily V member 1target
DB00316AcetaminophenSerum albumincarrier
DB00316AcetaminophenFatty-acid amide hydrolase 1enzyme
DB00316AcetaminophenGlutathione S-transferase Penzyme
DB00316AcetaminophenGlutathione S-transferase Mu 1enzyme
DB00062Albumin humanNitric oxidetarget
DB00835BrompheniramineHistamine H1 receptortarget
DB00835BrompheniramineMuscarinic acetylcholine receptor M1target
DB00835BrompheniramineMuscarinic acetylcholine receptor M2target
DB00835BrompheniramineMuscarinic acetylcholine receptor M3target
DB00835BrompheniramineMuscarinic acetylcholine receptor M4target
DB00835BrompheniramineMuscarinic acetylcholine receptor M5target
DB00354BuclizineHistamine H1 receptortarget
DB00354BuclizineMuscarinic acetylcholine receptor M1target
DB01222BudesonideGlucocorticoid receptortarget
DB01222BudesonideCytochrome P450 3A4enzyme
DB01222BudesonideCytochrome P450 3A5enzyme
DB01222BudesonideBile salt export pumptransporter
DB01222BudesonideP-glycoprotein 1transporter
DB01222BudesonideAnnexin A1target
DB01222BudesonideCytochrome P450 3A Subfamilyenzyme
DB01222BudesonideCytochrome P450 2A6enzyme
DB01222BudesonideCytochrome P450 1B1enzyme
DB01222BudesonideCytochrome P450 2B6enzyme
DB01222BudesonideCytochrome P450 2C8enzyme
DB01222BudesonideCytochrome P450 2C9enzyme
DB01222BudesonideCytochrome P450 2C19enzyme
DB01222BudesonideCorticosteroid-binding globulincarrier
DB01222BudesonideSolute carrier organic anion transporter family member 1A2transporter
DB01222BudesonideSolute carrier family 22 member 8transporter
DB01222BudesonideSerum albumincarrier
DB08936ChlorcyclizineHistamine H1 receptortarget
DB01114ChlorpheniramineHistamine H1 receptortarget
DB01114ChlorpheniramineCytochrome P450 3A4enzyme
DB01114ChlorpheniramineCytochrome P450 2D6enzyme
DB01114ChlorpheniramineSodium-dependent serotonin transportertarget
DB01114ChlorpheniramineSodium-dependent noradrenaline transportertarget
DB01114ChlorpheniramineSodium-dependent dopamine transportertarget
DB01114ChlorpheniramineCytochrome P450 3A5enzyme
DB01114ChlorpheniramineCytochrome P450 3A7enzyme
DB01114ChlorpheniramineSolute carrier family 22 member 2transporter
DB01114ChlorpheniramineSolute carrier family 22 member 1transporter
DB14006Choline salicylateCholine-phosphate cytidylyltransferase Btarget
DB14006Choline salicylateAcetylcholinesterasetarget
DB14006Choline salicylateCholine-phosphate cytidylyltransferase Atarget
DB14006Choline salicylatePhospholipase D2target
DB14006Choline salicylateCholinesterasetarget
DB14006Choline salicylatePhospholipase D1target
DB14006Choline salicylateSolute carrier family 22 member 2transporter
DB14006Choline salicylateSolute carrier family 22 member 1transporter
DB14006Choline salicylateSolute carrier family 22 member 3transporter
DB14006Choline salicylateSolute carrier family 22 member 5transporter
DB14006Choline salicylateSolute carrier family 22 member 4transporter
DB14006Choline salicylateCholine/ethanolaminephosphotransferase 1enzyme
DB14006Choline salicylateCholine transporter-like protein 1transporter
DB14006Choline salicylateCholine transporter-like protein 4transporter
DB14006Choline salicylateCholine transporter-like protein 3transporter
DB14006Choline salicylateCholine/ethanolamine kinaseenzyme
DB14006Choline salicylateCholine O-acetyltransferaseenzyme
DB14006Choline salicylateCholine kinase alphaenzyme
DB14006Choline salicylateCholine dehydrogenase, mitochondrialenzyme
DB14006Choline salicylateHigh affinity choline transporter 1transporter
DB14006Choline salicylateNeuronal acetylcholine receptor subunit alpha-7target
DB09555Dexchlorpheniramine maleateCytochrome P450 2D6enzyme
DB09555Dexchlorpheniramine maleateHistamine H1 receptortarget
DB09555Dexchlorpheniramine maleateSolute carrier family 22 member 1carrier
DB09555Dexchlorpheniramine maleateSolute carrier family 22 member 2carrier
DB09555Dexchlorpheniramine maleateCytochrome P450 3A4enzyme
DB08801DimetindeneMuscarinic acetylcholine receptor M2target
DB08801DimetindeneHistamine H1 receptortarget
DB01075DiphenhydramineHistamine H1 receptortarget
DB01075DiphenhydramineCytochrome P450 2D6enzyme
DB01075DiphenhydramineCytochrome P450 2C9enzyme
DB01075DiphenhydramineCytochrome P450 2C19enzyme
DB01075DiphenhydramineSolute carrier family 22 member 2transporter
DB01075DiphenhydramineSolute carrier family 22 member 5transporter
DB01075DiphenhydramineProstaglandin G/H synthase 1enzyme
DB01075DiphenhydramineMuscarinic acetylcholine receptor M2target
DB06691MepyramineCytochrome P450 2D6enzyme
DB06691MepyramineHistamine H1 receptortarget
DB06691MepyramineSolute carrier family 22 member 4transporter
DB06691MepyramineSolute carrier family 22 member 5transporter
DB01069PromethazineDopamine D2 receptortarget
DB01069PromethazineHistamine H1 receptortarget
DB01069PromethazineMuscarinic acetylcholine receptor M4target
DB01069PromethazineMuscarinic acetylcholine receptor M1target
DB01069PromethazineMuscarinic acetylcholine receptor M5target
DB01069PromethazineMuscarinic acetylcholine receptor M2target
DB01069PromethazineMuscarinic acetylcholine receptor M3target
DB01069PromethazineCalmodulintarget
DB01069PromethazineCytochrome P450 2D6enzyme
DB01069PromethazineCytochrome P450 2B6enzyme
DB01069PromethazineP-glycoprotein 1transporter
DB01069PromethazineCytochrome P450 2C9enzyme
DB01069PromethazineHistamine H2 receptortarget
DB01069PromethazineAlpha adrenergic receptortarget
DB01069PromethazineP2 Purinoceptorstarget
DB01069PromethazineVoltage-gated sodium channel alpha subunittarget
DB01069PromethazineVoltage-gated Potassium Channelstarget
DB01069PromethazineCanalicular multispecific organic anion transporter 2transporter
DB01069PromethazineMultidrug resistance-associated protein 4transporter
DB01069PromethazineSerum albumincarrier
DB06764TetryzolineAlpha-1A adrenergic receptortarget
DB11235ThonzylamineHistamine H1 receptortarget
DB11235ThonzylamineMuscarinic acetylcholine receptor M1target
DB11235ThonzylamineMuscarinic acetylcholine receptor M2target
DB11235ThonzylamineMuscarinic acetylcholine receptor M3target
DB11235ThonzylamineMuscarinic acetylcholine receptor M4target
DB11235ThonzylamineMuscarinic acetylcholine receptor M5target
DB00427TriprolidineHistamine H1 receptortarget
DrugDrug NamePhaseStatusCount
DB01234Dexamethasone0Not Yet Recruiting1
DB00742Mannitol0Completed1
DB01222Budesonide1Completed1
DB00341Cetirizine1Completed4
DB00341Cetirizine1Not Yet Recruiting1
DB01114Chlorpheniramine1Completed2
DB00283Clemastine1Completed1
DB06282Levocetirizine1Completed1
DB11856Ligelizumab1Completed1
DB00455Loratadine1Completed1
DB01069Promethazine1Completed1
DB00852Pseudoephedrine1Completed2
DB01114Chlorpheniramine1 / 2Completed1
DB13904Cat dander extract2Completed1
DB10399Felis catus skin2Completed1
DB00043Omalizumab2Completed1
DB00043Omalizumab2Terminated1
DB00062Albumin human2 / 3Completed1
DB01222Budesonide2 / 3Completed1
DB00169Cholecalciferol2 / 3Unknown Status1
DB00967Desloratadine2 / 3Completed1
DB00983Formoterol2 / 3Completed1
DB00635Prednisone2 / 3Completed1
DB01001Salbutamol2 / 3Completed1
DB11094Vitamin D2 / 3Unknown Status1
DB12768BCG vaccine3Active Not Recruiting1
DB00283Clemastine3Unknown Status1
DB01234Dexamethasone3Unknown Status1
DB13867Fluticasone3Unknown Status1
DB00588Fluticasone propionate3Completed2
DB00455Loratadine3Completed2
DB00764Mometasone3Completed1
DB00764Mometasone3Unknown Status1
DB14512Mometasone furoate3Completed2
DB00768Olopatadine3Completed2
DB00635Prednisone3Completed2
DB01001Salbutamol3Completed2
DB00972Azelastine4Terminated1
DB00341Cetirizine4Completed2
DB00169Cholecalciferol4Completed1
DB00967Desloratadine4Completed2
DB00303Ertapenem4Unknown Status1
DB00950Fexofenadine4Completed1
DB00591Fluocinolone acetonide4Completed1
DB00588Fluticasone propionate4Terminated1
DB09415Meglumine4Completed1
DB00994Neomycin4Completed1
DB00043Omalizumab4Unknown Status1
DB11614Rupatadine4Unknown Status1
DB11094Vitamin D4Completed1
DB01060AmoxicillinNot AvailableCompleted1
DB10404Anthoxanthum odoratum pollenNot AvailableCompleted1
DB01114ChlorpheniramineNot AvailableTerminated1
DB01410CiclesonideNot AvailableCompleted1
DB10379Dactylis glomerata pollenNot AvailableCompleted1
DB01234DexamethasoneNot AvailableCompleted1
DB13867FluticasoneNot AvailableCompleted1
DB10389Lolium perenne pollenNot AvailableCompleted1
DB00471MontelukastNot AvailableCompleted1
DB00043OmalizumabNot AvailableCompleted1
DB00043OmalizumabNot AvailableTerminated1
DB00043OmalizumabNot AvailableUnknown Status1
DB10394Phleum pratense pollenNot AvailableCompleted1
DB10366Poa pratensis pollenNot AvailableCompleted1
DB00860PrednisoloneNot AvailableCompleted1
DB14631Prednisolone phosphateNot AvailableCompleted1