NCT00541853
CCB Safety Study in Treatment of Hypertension of ADPKD treatment 4 unknown_status NCT00890279
Efficacy and Safety Study of Second-Line Treatment for Hypertension With Autosomal Dominant Polycystic Kidney Disease(ADPKD) treatment 2 unknown_status NCT00571909
Autosomal Dominant Polycystic Kidney Disease (ADPKD) Pain Study No drug interventions treatment Not Available completed NCT00784030
High Water Intake to Slow Progression of Polycystic Kidney Disease No drug interventions basic_science Not Available completed NCT00067977
Clinical Trial to Slow the Progression of ADPKD No drug interventions treatment Not Available unknown_status NCT06391450
Study of Empagliflozin in Patients with Autosomal Dominant Polycystic Kidney Disease (EMPA-PKD) treatment 4 recruiting NCT04907799
Daily Caloric Restriction in ADPKD No drug interventions treatment Not Available recruiting NCT05228574
Treatment of Vascular Stiffness in ADPKD treatment 4 recruiting NCT06582875
Glucagon-Like Peptide-1 Receptor Agonist in ADPKD treatment 2 not_yet_recruiting NCT05401409
Effect of Beetroot Juice on Reducing Hypertension in Autosomal Dominant Polycystic Kidney Disease No drug interventions treatment Not Available completed NCT03596957
Subacute Effect of Tolvaptan on Total Kidney Volume in Adult Patients With Autosomal Dominant Polycystic Kidney Disease treatment 4 unknown_status NCT05500157
Assessment of Treatment With Laparoscopic Fenestration or Aspiration Sclerotherapy for Large Symptomatic Hepatic Cysts No drug interventions treatment Not Available recruiting NCT05646420
Thyroid Hormones in ADPKD No drug interventions prevention Not Available completed NCT04111692
A Prospective Observational Study of Foam Sclerotherapy . No drug interventions Not Available Not Available recruiting NCT03918447
A Trial of Bardoxolone Methyl in Patients With ADPKD - FALCON treatment 3 terminated NCT03749447
An Extended Access Program for Bardoxolone Methyl in Patients With CKD (EAGLE) treatment 3 terminated NCT05478083
A GnRH Agonist IN Pre-menopausal Women STudy to Treat Severe Polycystic Liver Disease treatment 2 recruiting NCT03366337
A Phase 2 Trial of the Safety and Efficacy of Bardoxolone Methyl in Patients With Rare Chronic Kidney Diseases - PHOENIX treatment 2 completed NCT03102632
A Clinical Trial of Water Therapy for Autosomal Dominant Polycystic Kidney Disease No drug interventions treatment Not Available completed NCT03203642
Study of the Efficacy and Safety of Tesevatinib in Subjects With ADPKD treatment 2 completed NCT06496542
Renal Oxygen Consumption, Insulin Sensitivity, and Daily Caloric Restriction in ADPKD No drug interventions treatment Not Available recruiting NCT03273413
Statin Therapy in Patients With Early Stage ADPKD treatment 4 active_not_recruiting NCT04310319
Wishing to Decrease Aquaresis in ADPKD Patients Treated With a V2Ra; the Effect of Regulating Protein and Salt No drug interventions treatment Not Available unknown_status NCT06193616
Outcome of ADPKD With Octreotide LAR Not Available Not Available recruiting NCT03858439
Dietary Intervention in ADPKD on Tolvaptan No drug interventions treatment Not Available completed NCT05996731
Developing a Pipeline to Employ RNA-Seq as a Complementary Diagnostic Tool in Rare Diseases No drug interventions diagnostic Not Available recruiting NCT04908462
To Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Oral AL01211 in Healthy Volunteers No drug interventions treatment 1 completed NCT04064346
Efficacy and Safety of Lixivaptan in the Treatment of Autosomal Dominant Polycystic Kidney Disease treatment 3 terminated NCT06100133
Treat Autosomal Dominant Polycystic Kidney Disease With Oral Ketone Ester? No drug interventions treatment 2 not_yet_recruiting NCT03764605
Metformin vs Tolvaptan for Treatment of Autosomal Dominant Polycystic Kidney Disease treatment 3 unknown_status NCT03717883
ADPKD Alterations in Hepatic Transporter Function No drug interventions Not Available Not Available completed NCT04152837
Safety of Lixivaptan in Subjects Previously Treated With Tolvaptan for Autosomal Dominant Polycystic Kidney Disease treatment 3 terminated NCT02776241
Effect of Water Intake and Water Restriction on Total Kidney Volume in Autosomal Dominant Polycystic Kidney Disease No drug interventions diagnostic Not Available completed NCT04472624
Short Term Induction of Ketosis in PKD No drug interventions other Not Available completed NCT05521191
A Study of RGLS8429 in Patients With Autosomal Dominant Polycystic Kidney Disease No drug interventions treatment 1 recruiting NCT05373264
HYDROchlorothiazide to PROTECT Polycystic Kidney Disease Patients and Improve Their Quality of Life treatment 3 not_yet_recruiting NCT01853553
Mineralocorticoid Antagonism and Endothelial Dysfunction in Autosomal Dominant Polycystic Kidney Disease (ADPKD) treatment 3 completed NCT01632605
The Vienna RAP Pilot Study Not Available Not Available completed NCT06416761
Genetics in the Progression of Nephropathies No drug interventions Not Available Not Available recruiting NCT05014178
Kidney Sodium Functional Imaging No drug interventions Not Available Not Available recruiting NCT06085807
Genetic Testing in Autosomal Dominant Polycystic Kidney Disease No drug interventions Not Available Not Available recruiting NCT00345137
Effects of Systemic NO-Inhibition on Renal Hemodynamics in Patiens With Polycystic Kidney Disease and Chronic Glomerulonephritis Not Available 1 completed NCT04338048
Autosomal Dominant Polycystic Kidney Disease (ADPKD) Study No drug interventions Not Available Not Available recruiting NCT04680780
Ketogenic Dietary Interventions in Autosomal Dominant Polycystic Kidney Disease (ADPKD) No drug interventions other Not Available completed NCT02161068
Clinical Care of Autosomal Polycystic Kidney Disease: Retrospective Analysis and Prospective PKD Genotyping No drug interventions Not Available Not Available completed NCT06618638
Shared Decision Making for Choosing Autosomal DOminant Polycystic Kidney Disease Treatment No drug interventions treatment Not Available not_yet_recruiting NCT02497521
The German ADPKD Tolvaptan Treatment Registry No drug interventions Not Available Not Available recruiting NCT06594367
A Possible Founding PKD2 Mutation Associated with Variable Phenotypes of ADPKD in Bergamo Province No drug interventions Not Available Not Available not_yet_recruiting NCT01214421
Tolvaptan Extension Study in Participants With ADPKD treatment 3 completed NCT02115659
Triptolide-Containing Formulation as Treatment for Autosomal Dominant Polycystic Kidney Disease (ADPKD) treatment 3 unknown_status NCT02127437
Lanreotide In Polycystic Kidney Disease Study treatment 3 completed NCT04689074
Establishment of the Human Intestinal and Salivary Microbiota Biobank - Kidney Diseases No drug interventions Not Available Not Available completed NCT06289998
Study of Tamibarotene in Patients With ADPKD treatment 2 recruiting NCT02964273
Safety, Pharmacokinetics, Tolerability and Efficacy of Tolvaptan in Children and Adolescents With ADPKD (Autosomal Dominant Polycystic Kidney Disease) treatment 3 completed NCT02925221
Canadian Medical Assessment of JINARC™ Outcomes Registry No drug interventions Not Available Not Available recruiting NCT02616055
Long-Term Treatment and Follow up of Subjects Completing 24 Months of Treatment With Tesevatinib on Study KD019-101 treatment 2 terminated NCT02225860
Diet as a Potential Treatment for Autosomal Dominant Polycystic Kidney Disease No drug interventions treatment 2 / 3 completed NCT02112136
Clinical and Molecular Description of PKD1 and PKD2 Mutation Negative Carriers in ADPKD No drug interventions diagnostic Not Available completed NCT01430494
Observational Study in Patients With Autosomal Dominant Polycystic Kidney Disease No drug interventions Not Available Not Available completed NCT00309283
Somatostatin in Polycystic Kidney: a Long-term Three Year Follow up Study treatment 3 completed NCT03949894
Evaluating the Safety and effectivenesS in Adult KorEaN Patients Treated With Tolvaptan for Management of Autosomal domInAnt poLycystic Kidney Disease treatment 4 completed NCT06345755
A Phase 1 Study to Evaluate Safety, Tolerability, and Pharmacokinetics (PK) of VX-407 in Healthy Participants treatment 1 recruiting NCT01616927
Study of Lanreotide to Treat Polycystic Kidney Disease treatment 3 unknown_status NCT01223755
Sirolimus In Autosomal Dominant Polycystic Kidney Disease And Severe Renal Insufficiency treatment 2 / 3 terminated NCT00346918
Sirolimus (Rapamune®) for Autosomal Dominant Polycystic Kidney Disease (ADPKD) treatment 3 completed NCT01280721
A Study to Investigate the Long-term Safety and Efficacy of Tolvaptan in Patients With Autosomal Dominant Polycystic Kidney Disease (ADPKD) [Extension of Trial 156-04-251 in Japan] treatment 3 completed NCT04536688
A Study of RGLS4326 in Patients With Autosomal Dominant Polycystic Kidney Disease No drug interventions treatment 1 completed NCT00428948
Tolvaptan Phase 3 Efficacy and Safety Study in Autosomal Dominant Polycystic Kidney Disease (ADPKD) treatment 3 completed NCT03687554
Effect of Venglustat in Patients With Renal Impairment treatment 1 completed NCT04363554
The Kidneys Ability to Concentrate and Dilute Urine in Patients With Autosomal Dominant Polycystic Kidney Disease No drug interventions basic_science Not Available completed NCT03523728
A Medical Research Study Designed to Determine if Venglustat Can be a Future Treatment for ADPKD Patients treatment 2 / 3 terminated NCT05510115
Feasibility of Study of Empagliflozin in Patients With Autosomal Dominant Polycystic Kidney Disease treatment 2 recruiting NCT03342742
Daily Caloric Restriction and Intermittent Fasting in Overweight and Obese Adults With Autosomal Dominant Polycystic Kidney Disease No drug interventions other Not Available completed NCT02494141
Curcumin Therapy to Treat Vascular Dysfunction in Children and Young Adults With ADPKD treatment 4 completed NCT02656017
Metformin as a Novel Therapy for Autosomal Dominant Polycystic Kidney Disease treatment 2 completed NCT03803124
Effect of Tolvaptan on Renal Plasma Flow (RPF) and Glomerular Filtration Rate (GFR) in ADPKD basic_science 3 completed NCT01559363
A Safety, Pharmacokinetic & Dose-Escalation Study of KD019 in Subjects With Autosomal Dominant Polycystic Kidney Disease treatment 1 / 2 completed NCT02021110
Ursodeoxycholic Acid as Treatment for Polycystic Liver Disease treatment 2 completed NCT04407481
PErfusioN, OxyGen ConsUmptIon and ENergetics in ADPKD (PENGUIN) Not Available Not Available completed NCT00426153
Octreotide in Severe Polycystic Liver Disease treatment 2 / 3 completed NCT00413777
Tolvaptan Open-label Pilot Efficacy, Tolerability, and Safety Study in Autosomal Dominant Polycystic Kidney Disease (ADPKD) treatment 2 completed NCT01589705
The Relation Between Uric Acid Level and Endothelial Dysfunction in Patients With Polycystic Kidney Disease No drug interventions Not Available Not Available terminated NCT00565097
Lanreotide as Treatment of Polycystic Livers treatment 2 / 3 completed NCT02903511
Feasibility Study of Metformin Therapy in ADPKD treatment 2 completed NCT00410007
The Effect of High and Low Sodium Intake on Urinary Aquaporin-2 in Autosomal Dominant Polycystic Kidney Disease No drug interventions other Not Available completed NCT04534985
Time Restricted Feeding in Autosomal Dominant Polycystic Kidney Disease No drug interventions other Not Available completed NCT02251275
Long Term Safety of Immediate-release Tolvaptan in Subjects With Autosomal Dominant Polycystic Kidney Disease treatment 3 completed NCT02847624
Post-Marketing Surveillance Study of Tolvaptan in Patients With ADPKD Not Available Not Available completed NCT00456365
Effect of Statin Therapy on Disease Progression in Autosomal Dominant Polycystic Kidney Disease (ADPKD) treatment 3 completed NCT01114594
Pilot Study of RNA as a Biomarker for Autosomal Dominant Polycystic Kidney Disease No drug interventions Not Available Not Available completed NCT01233869
Bosutinib For Autosomal Dominant Polycystic Kidney Disease treatment 2 completed NCT04023214
The Role of Endothelial Dysfunction in Adult Polycystic Kidney Disease No drug interventions Not Available Not Available completed NCT03493802
Assessment of Longitudinal Changes in Endothelial Function and Oxidative Stress in Normotensive Patients With ADPKD No drug interventions Not Available Not Available completed NCT02250287
New Quantitive MRI Parameters in Assessing Kidneys of Autosomal Dominant Polycystic Kidney Disease No drug interventions Not Available Not Available completed NCT00598377
Adrenal Functions in Autosomal Dominant Polycystic Kidney Disease diagnostic Not Available completed NCT02160145
Efficacy and Safety of Tolvaptan in Subjects With Chronic Kidney Disease Between Late Stage 2 to Early Stage 4 Due to Autosomal Dominant Polycystic Kidney Disease treatment 3 completed NCT05288998
Intrarenal Microvasculature in ADPKD No drug interventions Not Available Not Available recruiting NCT05870007
Atorvastatin and Alkali Therapy in Patients With Autosomal Dominant Polycystic Kidney Disease treatment 2 enrolling_by_invitation NCT06065852
National Registry of Rare Kidney Diseases No drug interventions Not Available Not Available recruiting NCT02119052
Effects of Somatostatin on Liver in ADPKD No drug interventions treatment 2 / 3 completed NCT02134899
The Efficacy of Everolimus in Reducing Total Native Kidney Volume in Polycystic Kidney Disease Transplanted Recipients treatment 3 completed NCT03970018
ADPKD and Peritoneal Dialysis: How Anticipate Peritoneal Pressure? No drug interventions Not Available Not Available completed NCT01022424
A Long-term Administration Study of OPC-41061 in Patients With Autosomal Dominant Polycystic Kidney Disease (ADPKD) (2) [Extension of Study 156-05-002] treatment 3 completed NCT04284657
Pravastatin and Alkali Therapy in Patients With Autosomal Dominant Polycystic Kidney Disease treatment 2 enrolling_by_invitation NCT01451827
8-Week Study of Tolvaptan Dose Forms in Autosomal Dominant Polycystic Kidney Disease (ADPKD) treatment 2 completed NCT01210560
Dose-finding Study of New Tolvaptan Formulation in Subjects With ADPKD treatment 2 completed NCT02887729
Analysis of Clinical and Molecular Genetic Data Influencing the Evolution and Response to Therapy of ADPKD Patients (Autosomal Dominant Polycystic Kidney Disease) No drug interventions Not Available Not Available unknown_status NCT00414440
Efficacy, Safety and Tolerability of Everolimus in Preventing End-stage Renal Disease in Patients With Autosomal Dominant Polycystic Kidney Disease treatment 4 completed NCT01336972
Short-term Renal Hemodynamic Effects of Tolvaptan in Subjects With Autosomal Dominant Polycystic Kidney Disease (ADPKD) treatment 2 completed NCT00841568
A Long-term Administration Study of OPC-41061 in Patients With Autosomal Dominant Polycystic Kidney Disease (ADPKD) [Extension of Study 156-04-001] treatment 2 completed NCT02933268
High Water Intake in Polycystic Kidney Disease No drug interventions treatment Not Available completed NCT04344769
Characterization of the Nrf2 Response in Patients With Autosomal Dominant Polycystic Kidney Disease (ADPKD) No drug interventions Not Available Not Available recruiting NCT01377246
Somatostatin In Patients With Autosomal Dominant Polycystic Kidney Disease And Moderate To Severe Renal Insufficiency treatment 3 completed NCT05193981
A Study to Evaluate Homocysteine Metabolism and Endothelial Function in ADPKD No drug interventions Not Available Not Available recruiting NCT01810614
A New Diet for Patients With Autosomal Dominant Polycystic Disease (ADPKD) No drug interventions prevention Not Available completed NCT03901521
Autosomal Dominant Polycystic Kidney Disease Somatic Mutation Biorepository No drug interventions Not Available Not Available enrolling_by_invitation NCT02848521
A Study Measuring Quality of Life, Treatment Preference and Satisfaction of ADPKD Patients in Europe No drug interventions Not Available Not Available unknown_status NCT01039987
Consortium for Radiologic Imaging Studies of Polycystic Kidney Disease No drug interventions Not Available Not Available completed NCT03541447
Tolvaptan-Octreotide LAR Combination in ADPKD treatment 2 completed NCT00920309
Rapamycin as Treatment for Autosomal Dominant Polycystic Kidney Disease (ADPKD): The Role of Biomarkers in Predicting a Response to Therapy treatment 2 / 3 terminated NCT02322385
Clinical Implications of DNA Analysis on ADPKD No drug interventions Not Available Not Available completed NCT02187432
The Eurocyst Initiative: Building a Network of ADPKD Reference Centers Across Europe No drug interventions Not Available Not Available unknown_status NCT02084849
ADPKD Cohort Study No drug interventions Not Available Not Available completed NCT02119013
Effects of Somatostatin on ADPKD Heart No drug interventions treatment 2 / 3 completed NCT04630613
NOX4 and Related Biomarkers in ADPKD No drug interventions Not Available Not Available recruiting NCT03487913
The ELiSA Study - Evaluation of Lixivaptan in Subjects With Autosomal Dominant Polycystic Kidney Disease treatment 2 completed NCT02746419
The Safety and Efficacy of Catheter-based Renal Denervation Using the Vessix™ Renal Denervation System in Autosomal Dominant Polycystic Kidney Disease (ADPKD) Patients With Severe Debilitating Pain No drug interventions treatment Not Available withdrawn NCT06435858
Short-term Effects of an SGLT2 Inhibitor on Divalent Ions in Autosomal Dominant Polycystic Kidney Disease treatment 4 not_yet_recruiting NCT01348035
Efficacy Study of Water Drinking on PKD Progression. No drug interventions Not Available Not Available completed NCT04939935
Implementation of Metformin theraPy to Ease Decline of Kidney Function in Polycystic Kidney Disease (IMPEDE-PKD) treatment 3 recruiting NCT02527863
Effect of the Aquaretic Tolvaptan on Nitric Oxide System treatment 2 completed NCT04578548
A Study to Evaluate the Effects of GLPG2737 in Participants With Autosomal Dominant Polycystic Kidney Disease (ADPKD) No drug interventions treatment 2 terminated NCT02729662
Efficacy of Tolvaptan on ADPKD Patients treatment Not Available unknown_status NCT05190744
PB to Treat Hereditary Nephrogenic Diabetes Insipidus, ADPKD Treated With Tolvaptan, and Severely Polyuric Patients With Previous Lithium Administration No drug interventions supportive_care 2 recruiting NCT05460169
Renal Denervation in ADPKD- RDN-ADPKD Study No drug interventions treatment Not Available recruiting NCT00759369
Water as Therapy in Autosomal Dominant Polycystic Kidney Disease (ADPKD) No drug interventions treatment Not Available completed NCT01670110
Pasireotide LAR in Severe Polycystic Liver Disease treatment 2 completed NCT01932450
Radiofrequency Ablation for ADPKD Blood Pressure and Disease Progression Control No drug interventions treatment 2 unknown_status NCT01988038
Repository Study of Autosomal Dominant Polycystic Kidney Disease No drug interventions Not Available Not Available withdrawn