Alkylating Drugs
Highly reactive chemicals that introduce alkyl radicals into biologically active molecules and thereby prevent their proper functioning. Many are used as antineoplastic agents, but most are very toxic, with carcinogenic, mutagenic, teratogenic, and immunosuppressant actions. A DrugBank category of 49 drugs. 25 of them are approved.
- ATC classification
- Also known as
- Agents, Alkylating · Alkylating Agent · Alkylating Agents · Alkylating Drug · Alkylators
- Drugs
- Adozelesin
- Altretamine
- Bendamustine
- Bizelesin
- Busulfan
- Carboquone
- Carmustine
- Carzelesin
- Chlorambucil
- Cyclophosphamide
- Dacarbazine
- Dianhydrogalactitol
- Estramustine
- Estramustine phosphate
- Etoglucid
- Fotemustine
- Ifosfamide
- Irofulven
- Lomustine
- Lurbinectedin
- Mannomustine
- Mannosulfan
- Mechlorethamine
- Melphalan
- Melphalan flufenamide
What you can answer from here — as of September 25, 2018
Which targets do Alkylating Drugs share, and which companies have late-stage candidates in this class?
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