Antineoplastic Agents, Alkylating
DBCAT000592Pharmacologic class
A class of drugs that differs from other alkylating agents used clinically in that they are monofunctional and thus unable to cross-link cellular macromolecules. Among their common properties are a requirement for metabolic activation to... A DrugBank category of 41 drugs. 21 of them are approved.
- Also known as
- Alkylating Agents, Antineoplastic · Alkylating Antineoplastic Agents · Alkylating Antineoplastic Drugs · Alkylating Antineoplastics · Alkylating Drugs, Antineoplastic
- Drugs
- Adozelesin
- Altretamine
- Bendamustine
- Bizelesin
- Busulfan
- Carboquone
- Carmustine
- Carzelesin
- Chlorambucil
- Cyclophosphamide
- Dacarbazine
- Dianhydrogalactitol
- Estramustine
- Estramustine phosphate
- Etoglucid
- Ifosfamide
- Irofulven
- Lomustine
- Mannomustine
- Mechlorethamine
- Melphalan
- Melphalan flufenamide
- Minnelide
- Minnelide free acid
- Mitobronitol
What you can answer from here — as of August 24, 2016
Which targets do Antineoplastic Agents, Alkylating share, and which companies have late-stage candidates in this class?
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