Peptic Ulcer Disease

Also known as: Gastroduodenal ulcer / Ulcer gastroduodenal / Peptic ulcer, site unspecified / Peptic ulcer syndrome / Ulcer syndrome peptic / Syndrome peptic ulcer / PUD / Peptic ulceration / GDU / Peptic ulcer / Peptic ulcer (disorder) / Ulcer peptic

Drug	Drug Name	Drug Description
DB00475	Chlordiazepoxide	A benzodiazepine used to treat the withdrawal symptoms of acute alcoholism, to treat preoperative anxiety, and to treat anxiety over a short term period.
DB00771	Clidinium	A synthetic anticholinergic used to treat peptic ulcer disease, colicky abdominal pain, diverticulitis, and IBS.
DB00585	Nizatidine	An H2 receptor antagonist used to treat GERD and a variety of ulcers.
DB00863	Ranitidine	A histamine H2 antagonist used to treat duodenal ulcers, Zollinger-Ellison syndrome, gastric ulcers, GERD, and erosive esophagitis.

Drug	Drug Name	Target	Type
DB00475	Chlordiazepoxide	GABA(A) Receptor	target
DB00475	Chlordiazepoxide	GABA(A) Receptor Benzodiazepine Binding Site	target
DB00475	Chlordiazepoxide	Cytochrome P450 3A4	enzyme
DB00771	Clidinium	Muscarinic acetylcholine receptor M1	target
DB00585	Nizatidine	Histamine H2 receptor	target
DB00585	Nizatidine	P-glycoprotein 1	transporter
DB00585	Nizatidine	Cholinesterase	enzyme
DB00863	Ranitidine	Histamine H2 receptor	target
DB00863	Ranitidine	Cytochrome P450 1A2	enzyme
DB00863	Ranitidine	Cytochrome P450 2D6	enzyme
DB00863	Ranitidine	Solute carrier family 22 member 1	transporter
DB00863	Ranitidine	P-glycoprotein 1	transporter
DB00863	Ranitidine	Solute carrier family 22 member 8	transporter
DB00863	Ranitidine	Cytochrome P450 3A4	enzyme
DB00863	Ranitidine	Acetylcholinesterase	target
DB00863	Ranitidine	Solute carrier family 22 member 2	transporter
DB00863	Ranitidine	Acetylcholinesterase	enzyme

Drug	Drug Name	Phase	Status	Count
DB00945	Acetylsalicylic acid	1	Completed	1
DB00945	Acetylsalicylic acid	1	Terminated	1
DB00736	Esomeprazole	1	Completed	1
DB00736	Esomeprazole	1	Terminated	1
DB01129	Rabeprazole	Not Available	Recruiting	1