Severe Opioid Dependence

Drug	Drug Name	Drug Description
DB00921	Buprenorphine	A partial opioid agonist used for management of severe pain that is not responsive to alternative treatments. Also used for maintenance treatment of opioid addiction.

Drug	Drug Name	Target	Type
DB00921	Buprenorphine	Kappa-type opioid receptor	target
DB00921	Buprenorphine	Mu-type opioid receptor	target
DB00921	Buprenorphine	Cytochrome P450 3A4	enzyme
DB00921	Buprenorphine	Cytochrome P450 2D6	enzyme
DB00921	Buprenorphine	P-glycoprotein 1	transporter
DB00921	Buprenorphine	ATP-binding cassette sub-family G member 2	transporter
DB00921	Buprenorphine	Cytochrome P450 2C9	enzyme
DB00921	Buprenorphine	Cytochrome P450 3A5	enzyme
DB00921	Buprenorphine	Cytochrome P450 2C8	enzyme
DB00921	Buprenorphine	Cytochrome P450 3A7	enzyme
DB00921	Buprenorphine	Delta-type opioid receptor	target
DB00921	Buprenorphine	Cytochrome P450 2C18	enzyme
DB00921	Buprenorphine	Cytochrome P450 2C19	enzyme
DB00921	Buprenorphine	Nociceptin receptor	target

Drug	Drug Name	Phase	Status	Count