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Fatty Acid Biosynthesis
smpdb.ca/view/SMP0000456MetabolicThe biosynthesis of fatty acids primarily occurs in liver and lactating mammary glands. … The production of palmitic acid can be summarized as the successive addition of two carbons to an initial acetyl moiety primer. After 7 cycles palimitic acid is released.
Drugs: Biotin · Acetoacetic acid · Butenoic Acid · Malonic acid · (R)-3-hydroxytetradecanoic acid · Lauric acid +8 moreEnzymes: Fatty acid synthaseGadoteric acid Metabolism
smpdb.ca/view/SMP0126924MetabolicGadoteric acid is indicated for intravenous use with magnetic resonance imaging (MRI) in brain (intracranial), spine and associated tissues in adult and pediatric patients (2 years of age and older) to … Gadoteric acid is a diagnostic contrast agent used with magnetic resonance imaging to provide contrast enhancement for intracranial and spinal lesions with abnormal blood brain barrier or abnormal vascularity
Drugs: Gadoteric acidSelenoamino Acid Metabolism
smpdb.ca/view/SMP0000029Metabolic3-phosphate (lysophosphatidic acid). … All phospholipids contain sn-glycerol-3-phosphate esterified with fatty acids at the sn-1 and sn-2 positions.
Arachidonic Acid Metabolism
smpdb.ca/view/SMP0000075MetabolicThis pathway describes the production and subsequent metabolism of arachidonic acid, an omega-6 fatty acid. … In resting cells arachidonic acid is present in the phospholipids (especially phosphatidylethanolamine and phosphatidylcholine) of membranes of the body’s cells, and is particularly abundant in the brain
Gastric Acid Production
smpdb.ca/view/SMP0000589PhysiologicalHCl and/or KCl, which are both constituents of stomach acid. … This digestive fluid is formed in the stomach (specifically by the parietal cells) and is mainly composed of hydrochloric acid (HCl).
Gadoxetic acid Metabolism
smpdb.ca/view/SMP0126873MetabolicGadoxetic acid is a gadolinium-based contrast agent used in magnetic resonance imaging (MRI) to help characterize lesions in the liver. … The water protons in the vicinity are disrupted such that the change the proton density and spin characteristics are detected and visualized by a device.
Drugs: Gadoxetic acidTranexamic Acid Action Pathway
smpdb.ca/view/SMP0000287Drug actionTranexamic acid is a synthetic version of an amino acid found in the body called lysine that plays a role in antifibrinolytic processes. It is used to stop bleeding and hemorrhaging in patients. … Tranexamic acid inhibits plasminogen.
Lysophosphatidic Acid LPA1 Signalling
smpdb.ca/view/SMP0063746SignalingLysophosphatidic acid (LPA) is a water-soluble phospholipid derivative and a potent signalling molecule that binds to six known lysophosphatidic acid receptors (LPARs), named LPA1-LPA6. … LPC, LPE, LPS) into LPA via autotaxin (ATX/Enpp2) and (2) the conversion of phosphatidic acid (PA) into LPA via phospholipase A1 or A2 (PLA1/PLA2).
Enzymes: Lysophosphatidic acid receptor 1Lysophosphatidic Acid LPA3 Signalling
smpdb.ca/view/SMP0063755SignalingLysophosphatidic acid (LPA) is a water-soluble phospholipid derivative and a potent signalling molecule that binds to six known lysophosphatidic acid receptors (LPARs), named LPA1-LPA6. … LPC, LPE, LPS) into LPA via autotaxin (ATX/Enpp2) and (2) the conversion of phosphatidic acid (PA) into LPA via phospholipase A1 or A2 (PLA1/PLA2).
Enzymes: Lysophosphatidic acid receptor 3