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Androgen and Estrogen Metabolism
smpdb.ca/view/SMP0000068MetabolicThis pathway describes the inactivation and catabolism of male (androgen) and female (estrogen) hormones. … Many steroid hormones are transformed by sulfatases, dehydrogenases and glucuronide transferases to enhance their solubility and to facilitate their elimination.
NAD+ Signalling and Aging
smpdb.ca/view/SMP0084271SignalingAn interesting link has emerged between NAD+ metabolism, SIRT1, SIRT3, and mitochondrial function. … NR and PARP inhibitors increased life span in worms via activation of the mitochondrial unfolded protein response UPRmt by sir2.1.
Glycine and Serine Metabolism
smpdb.ca/view/SMP0000004MetabolicThis pathway describes the synthesis and breakdown of several small amino acids, including glycine, serine, and cysteine. … All of these compounds share common intermediates and almost all can be biosynthesized from one another. Serine and glycine are not essential amino acids and can be synthesized from several routes.
Drugs: Pyridoxal phosphate · Tetrahydrofolic acid · Ademetionine · Pyruvic acid · Arginine · Adenosine phosphate +26 moreTaurine and Hypotaurine Metabolism
smpdb.ca/view/SMP0000021Metabolicand returning them to the bile. … This includes acids such as chenodeoxycholic acid and cholic acid, and in turn the formation of bile salts occurs.
Pantothenate and CoA Biosynthesis
smpdb.ca/view/SMP0000027MetabolicPantothenic acid, pantetheine 4’-phosphate and pantetheine are all found in red blood cells. … It is a precursor of coenzyme A, which is an essential part of many reactions in the body, specifically important in the production of compounds like cholesterol and different fatty acids.
Starch and Sucrose Metabolism
smpdb.ca/view/SMP0000058MetabolicThe action of enterocytes of the small intestine microvilli further break down limit dextrins and disaccharides into monosaccharides: glucose, galactose, and fructose. … Amylase enzymes secreted in saliva by the parotid gland and in the small intestine play an important role in initiating starch digestion.
Drugs: Pyridoxal phosphate · NADH · ATP · Calcium · Magnesium cation · Uridine diphosphate glucose +4 moreSpermidine and Spermine Biosynthesis
smpdb.ca/view/SMP0000445MetabolicSpermidine and spermine are produced in many tissues, as they are involved in the regulation of genetic processes from DNA synthesis to cell migration, proliferation, differentiation and apoptosis. … The Spermidine and Spermine Biosynthesis pathway highlights the creation of these cruicial polyamines.
Water
go.drugbank.com/drugs/DB09145ApprovedInvestigationalWater (chemical formula: H2O) is a transparent fluid which forms the world's streams, lakes, oceans and rain, and is the major constituent of the fluids of organisms. … Water is a liquid at standard ambient temperature and pressure, but it often co-exists on Earth with its solid state, ice; and gaseous state, steam (water vapor).
Mixtures: Medium Cuts and Scratches, Good Neighbor Pharmacy Emergency Preparedness and First Aid Contains 167 PiecesProducts: Xpect First aid Buffered Eye and Skin, fad first aid direct Buffered Eye and SkinPhenylalanine and Tyrosine Metabolism
smpdb.ca/view/SMP0000008Metabolicinto polypeptides (via tyrosyl tRNA synthetase and phenylalyl tRNA synthetase) and the conversion of phenylalanine to tyrosine via phenylalanine hydroxylase. … Tyrosine can be converted into L-DOPA, which is further converted into dopamine, norepinephrine (noradrenaline), and epinephrine (adrenaline).
Drugs: Pyridoxal phosphate · Phenylalanine · Adenosine phosphate · Tyrosine · Glutamic acid · ATP +11 moreArginine and Proline Metabolism
smpdb.ca/view/SMP0000020MetabolicThe arginine and proline metabolism pathway illustrates the biosynthesis and metabolism of several amino acids including arginine, ornithine, proline, citrulline, and glutamate in mammals. … After this, the mitochondrial citrulline is released from the small intestine enterocytes and into the bloodstream where it is taken up by the kidneys for arginine production.
Drugs: Pyridoxal phosphate · Ademetionine · Arginine · Aspartic acid · Ornithine · Adenosine phosphate +21 more