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Bile Acid Biosynthesis
smpdb.ca/view/SMP0000035MetabolicBile acids play a very important part in the digestion of foods, and are responsible for the absorption of water soluble vitamins in the small intestine. … conjugate and deoxycholic acid.
Androgen and Estrogen Metabolism
smpdb.ca/view/SMP0000068MetabolicThis pathway describes the inactivation and catabolism of male (androgen) and female (estrogen) hormones. … Inactive androgens and estrogens are mostly eliminated in the urine.
Phytanic Acid Peroxisomal Oxidation
smpdb.ca/view/SMP0000450MetabolicPhytanic acid, a branched chain fatty acid, is an important component of fatty acid intake, occuring in meat, fish and dairy products. … Due to its methylation, it cannot be a substrate for acyl-CoA dehydrogenase and cannot enter the mitochondrial beta oxidation pathway.
Enzymes: ATP-binding cassette sub-family D member 1, ATP-binding cassette sub-family D member 2Tiaprofenic Acid Action Pathway
smpdb.ca/view/SMP0000705Drug actionProstaglandin G/H synthase 1 and 2 catalyze the arachidonic acid to prostaglandin G2, and also catalyze prostaglandin G2 to prostaglandin H2 in the metabolism pathway. … Tiaprofenic Acid (also named tiaprofensaeure and surgam) is a nonsteroidal anti-inflammatory drug (NSAID). It can be used to treat pain (especially arthritic pain).
Enzymes: Prostaglandin-H2 D-isomeraseGlutaminolysis and Cancer
smpdb.ca/view/SMP0002298DiseaseOnce it reaches malic acid, it is transported outside the mitochondria and transformed into pyruvic acid and lactate. … The oxoglutaric acid can also be transformed into citric acid which then gets turned into acetyl coa and get incorporated into the lipid synthesis
Drugs: Pyridoxal phosphate · Pyruvic acid · Biotin · Aspartic acid · L-Glutamine · Succinic acid +9 moreEnzymes: Y+L amino acid transporter 1, Neutral amino acid transporter AMefenamic Acid Action Pathway
smpdb.ca/view/SMP0000109Drug actionMefenamic acid can block prostaglandin synthesis by the action of inhibition of prostaglandin G/H synthase 1 and 2. … Prostaglandin G/H synthase 1 and 2 catalyze the arachidonic acid to prostaglandin G2, and also catalyze prostaglandin G2 to prostaglandin H2 in the metabolism pathway.
Drugs: Glutamic acid · Glutathione · Mefenamic acid · Dinoprostone · Calcium · Magnesium cation +5 moreEnzymes: Prostaglandin-H2 D-isomeraseMycophenolic Acid Action Pathway
smpdb.ca/view/SMP0122722Drug actionMycophenolic acid is a selective, reversible and potent inhibitor of the enzyme. … Mycophenolic acid is an immunosuppressant drug and anti-proliferative drug derived from Penicillium stoloniferum.
Drugs: Tetrahydrofolic acid · Aspartic acid · L-Glutamine · Adenosine phosphate · Glutamic acid · Glycine +14 moreAminocaproic Acid Action Pathway
smpdb.ca/view/SMP0000286Drug actionAminocaproic acid, brand name Amicar, is a derivate of lysine and is an antifibrinolytic drug. Antifibrinolytics drugs are commonly used during major surgery to prevent significant blood loss. … This blockade inhibits plasminogen binding to fibrin and the conversion of plasminogen to plasmin. These prevents fibrin degradation and maintains the stability of fibrin clots.
Enzymes: Vitamin K-dependent gamma-carboxylase, Vitamin K epoxide reductase complex subunit 1Nicotinate and Nicotinamide Metabolism
smpdb.ca/view/SMP0000048MetabolicThese compounds can be found in the diet, where the mixture of nicotinic acid and nicotinamide are called vitamin B3 or niacin. … Nicotinate (niacin) and nicotinamide - more commonly known as vitamin B3 - are precursors of the coenzymes nicotinamide-adenine dinucleotide (NAD+) and nicotinamide-adenine dinucleotide phosphate (NADP
Acetylsalicylic Acid Action Pathway
smpdb.ca/view/SMP0000083Drug actionCOX-1 and -2 catalyze the conversion of arachidonic acid to prostaglandin G2 and prostaglandin G2 to prostaglandin H2. … Acetylsalicylic acid, also known as ASA or aspirin, belongs to a class of drugs known as non-steroidal anti-inflammatory drugs (NSAIDs).
Drugs: Glutamic acid · Glutathione · Dinoprostone · Acetylsalicylic acid · Calcium · Magnesium cation +5 moreEnzymes: Prostaglandin-H2 D-isomerase