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Timolol
go.drugbank.com/drugs/DB00373ApprovedInvestigational[L6727] Timolol was first approved by the FDA in 1978. … Timolol is a nonselective beta-adrenergic antagonist given in an eye drop solution to reduce intraocular pressure, or pressure in the eyes.
Synonyms: Timolol, TimololoInternational brands: TimoptolTimolol Action Pathway
smpdb.ca/view/SMP0000659Drug actionTimolol, much like propranolol or oxprenolol, begins its journey by inhibiting the beta-1 adrenergic receptors in the heart. … Timolol is a beta blocker medication, making it part of the antihypertensive drug class. It relieves symptoms such as tachycardia, vascular headaches, hypertension, angina and tremors.
Timolol Action Pathway (New)
smpdb.ca/view/SMP0124552Drug actionTimolol is a non-selective beta-adrenergic blocker used in the treatment of elevated intraocular pressure in ocular hypertension or open angle glaucoma. … The blockade of beta(2) receptors by timolol in the blood vessels leads to a decrease in peripheral vascular resistance, reducing blood pressure.
Drugs: ATP · Timolol · Calcium · Magnesium cation · Cyclic adenosine monophosphate · Pyrophosphoric acidTimolol B1-Adrenergic Cardiac Muscle Relaxation Action Pathway
smpdb.ca/view/SMP0126503Drug actionSome side effects of using Timolol may include eye pain, swollen eyelids, and dry mouth. … Timolol, when administered by the ophthalmic route, rapidly reduces intraocular pressure.
Timolol B2-Adrenergic Ciliary Muscle Contraction Action Pathway
smpdb.ca/view/SMP0126232Drug actionSome side effects of using Timolol may include eye pain, swollen eyelids, and dry mouth. … Timolol, when administered by the ophthalmic route, rapidly reduces intraocular pressure.
Drugs: ATP · Timolol · Potassium cation · Calcium · Magnesium cation · Cyclic adenosine monophosphateDorzolamide
go.drugbank.com/drugs/DB00869ApprovedInvestigational[A1304] First marketed in 1995,[A190624] dorzolamide is available in ophthalmic solutions as monotherapy marketed as Trusopt [L11377] or in combination with [timolol] as Cosopt PF.[L11380]
Mixtures: Dorzolamide HCl /Timolol Maleate, Dorzolamide HCl and Timolol MaleateBrimonidine
go.drugbank.com/drugs/DB00484ApprovedInvestigationalBrimonidine is an alpha-adrenergic agonist and 2-imidazoline derivative that was first introduced in 1996. It is considered to be a third generation alpha-2 aadrenergic receptor agonist, since it displays preferential binding at alpha-2 ...
Mixtures: Brimonidine Tartrate/Timolol Maleate, Brimonidine Tartrate/Timolol MaleateOpen Angle Glaucoma (OAG)
go.drugbank.com/conditions/DBCOND0046770Drugs: Acetazolamide · Carbamoylcholine · Echothiophate · Epinephrine · Latanoprost · Levobunolol +6 moreOcular Hypertension
go.drugbank.com/conditions/DBCOND0074237Increased Intra Ocular Pressure (IOP)
go.drugbank.com/conditions/DBCOND0049485