Open Angle Glaucoma (OAG) (DBCOND0046770)

Identifiers

Synonyms
Open-angle Glaucoma (OAG) / Open Angle-glaucoma / Glaucoma Open-Angle / Glaucoma, Open-Angle Glaucoma Eye / Open-Angle Glaucoma / Glaucoma, Open-Angle / Glaucoma, Open Angle / Open Angle Glaucoma / Glaucoma,Open-Angle / OAG - Open-Angle Glaucoma / Angle Glaucoma Open / Primary open-angle glaucoma / Glaucoma, Primary Open Angle / Primary open angle glaucoma (disorder) / Primary open angle glaucoma / Pigmentary glaucoma / Unspecified open-angle glaucoma / Open angle glaucoma NOS / Open-angle glaucoma (disorder) / Open-angle glaucoma, unspecified / Advanced open-angle glaucoma (disorder) / Glaucoma simplex / Pigmentary glaucoma (disorder)

Associated Data

Indicated Drugs and Targets
DrugDescriptionTargets
Acetazolamide
A carbonic anhydrase inhibitor used to treat edema from heart failure or medications, certain types of epilepsy, and glaucoma.
Bimatoprost
A prostaglandin analog used to treat hypotrichosis of the eyelashes and intraocular pressure in open angle glaucoma or ocular hypertension.
Brimonidine
An alpha-2 adrenergic agonist used to treat glaucoma and ocular hypertension, as well as facial erythema in rosacea.
Brinzolamide
A carbonic anhydrase inhibitor used for the reduction of elevated intraocular pressure in patients with ocular hypertension or open-angle glaucoma.
Carbamoylcholine
A direct acting miotic agent administered ophthalmically to decrease intraocular pressure after cataract surgery, and to induce miosis during surgery.
Dorzolamide
A carbonic anhydrase inhibitor used to treat high intraocular pressure in ocular hypertension and open angle glaucoma.
Echothiophate
An acetylcholinesterase inhibitor used in ophthalmic preparations to increase the drainage of intraocular fluid; most commonly used for the treatment of glaucoma.
Epinephrine
A hormone and neurotransmitter used to treat allergic reactions, to restore cardiac rhythm, and to control mucosal congestion, glaucoma, and asthma.
Latanoprost
An isopropyl ester prodrug used to treat increased intraocular pressure.
Levobunolol
A beta-adrenergic antagonist used for the reduction of elevated intraocular pressure in patients with ocular hypertension or open-angle glaucoma.
Methazolamide
A carbonic anhydrase inhibitor used to treat open angle glaucoma and acute angle closure glaucoma.
Metipranolol
A beta-adrenergic antagonist used for the reduction of elevated intraocular pressure in patients with ocular hypertension or open-angle glaucoma.
Netarsudil
A rho kinase inhibitor used to reduce intraocular pressure in patients with open angle glaucoma or ocular hypertension.
Omidenepag isopropyl
An agonist of the prostaglandin EP2 receptor indicated for the reduction of elevated intraocular pressure.
Pilocarpine
A muscarinic agonist used to treat dry mouth and various ophthalmic conditions, such as presbyopia, increased intraocular pressure, and angle-closure glaucoma.
Ripasudil
A rho kinase inhibitor indicated to treat ocular hypertension and open-angle glaucoma.
Tafluprost
An ophthalmic prostaglandin analog used to lower intraocular pressure in patients with ocular hypertension or open-angle glaucoma.
Timolol
A non-selective beta adrenergic blocker used in the treatment of elevated intraocular pressure in ocular hypertension or open angle glaucoma.
Travoprost
A prostaglandin analog used in the treatment of elevated intraocular pressure due to open angle glaucoma or ocular hypertension.
Unoprostone
A prostaglandin analogue used to lower intraocular pressure in patients with open-angle glaucoma or ocular hypertension who are clinically unresponsive to other ocular antihypertensive agents.
No drug targets
Clinical Trials
IdentifierTitleDrug(s)PurposePhaseStatus
NCT01318252
AL-54478 Proof of Concept Studytreatment2completed
NCT01114893
Travoprost Five Day Posology Studytreatment2completed
NCT06249152
Qlaris Study of QLS-111 in Combination With a PGA for OAG and/or OHT PatientsNo drug interventionstreatment2recruiting
NCT02083289
A 28 Day Study of ONO-9054 Ophthalmic Solution in Subjects With Ocular Hypertension (OHT) or Open-angle Glaucoma (OAG)treatment2completed
NCT02228577
Safety and Performance Study of the CyPass System Applier Model 241No drug interventionsNot AvailableNot Availablecompleted
NCT01097174
CyPass Clinical Experience StudyNo drug interventionsNot AvailableNot Availablecompleted
NCT04381611
INTEGRAL Study: A Longitudinal Study of Surgeries and Lasers in Glaucoma: Long-term Results and Success Predictors Analysed From a Large-scale Retrospective and Prospective Glaucoma RegisterNo drug interventionsNot AvailableNot Availableenrolling_by_invitation
NCT00306657
Normal Tension and Chronic Open Angle Glaucoma and Cerebrospinal Fluid CompositionNo drug interventionstreatmentNot Availableunknown_status
NCT02754596
Study Comparing Travoprost Intraocular Implants to Timolol Ophthalmic Solutiontreatment2completed
NCT06434155
Social History and Glaucoma ProgressionNo drug interventionsNot AvailableNot Availablecompleted
NCT04517786
MINIject (MINI SO627) in Patients With Open Angle Glaucoma Using Single Operator Delivery ToolNo drug interventionstreatmentNot Availableactive_not_recruiting
NCT04530084
A Single Center Proof Of Concept Study To Assess Intra And Perioperative Safety Profile Of OMNI Surgical SystemNo drug interventionstreatmentNot Availableunknown_status
NCT04615403
Study of Exchange of Travoprost Intraocular Implanttreatment2completed
NCT04005079
Pilocarpine After Combined Cataract/Trabectome Surgerytreatment3withdrawn
NCT03927443
A Comparative Study of SPARC's SDP-133 Once Daily and Lumigan in Subjects With Open Angle Glaucoma or Ocular Hypertensiontreatment3withdrawn
NCT02825264
STAR-LIFE Registry: STARflo Glaucoma Implant Clinical Experience ProgramNo drug interventionsNot AvailableNot Availableactive_not_recruiting
NCT02868502
Different Glaucoma Treatments Effect on Intraocular Pressure Fluctuation With Postural Change in Eyes With Open-angle GlaucomaNo drug interventionsNot AvailableNot Availableunknown_status
NCT01994564
Prevalence of Dyschromatopsia in Glaucoma PatientsNo drug interventionsNot AvailableNot Availablewithdrawn
NCT01304264
Intraocular Pressure, Blood Pressure, Ocular Perfusion and Blood Flow Fluctuations in Glaucoma PatientsNo drug interventionsNot AvailableNot Availablecompleted
NCT01330979
24-hour Efficacy of AR-12286No drug interventionstreatment2completed
NCT00838721
Evaluation of Pascal Laser TrabeculoplatyNo drug interventionstreatmentNot Availablecompleted
NCT00803803
Dose, Effects and Characteristics of Pilocarpinetreatment4completed
NCT00465803
A Phase IIIb Study of DuoTrav to Treat Glaucoma or Ocular Hypertensiontreatment3completed
NCT00928590
Safety Study of DuoTrav APS in Patients With Open-Angle Glaucoma or Ocular Hypertensiontreatment3completed
NCT01456390
Open-Angle Glaucoma Subjects With One Prior Trabeculectomy Treated Concurrently With One Suprachoroidal Stent and Two Trabecular Micro-bypass StentsNo drug interventionstreatmentNot Availablecompleted
NCT01699464
A Study Assessing the Safety and Ocular Hypotensive Efficacy of AR-12286 in Patients With Elevated Intraocular Pressure for 3 Monthstreatment2completed
NCT00465621
Dose Response Study of AL-37807 Ophthalmic Solution in Patients With Open-Angle Glaucoma or Ocular Hypertensiontreatment2completed
NCT00821002
A Phase 2 Study of Punctal Placement of the Latanoprost Punctal Plug Delivery System (L-PPDS)treatment2completed
NCT00323284
A Study of the Trabecular Micro-bypass Stent in Combination With Cataract Surgery in Subjects With Open Angle GlaucomaNo drug interventionstreatment3completed
NCT02339584
Efficacy and Safety of Brinzolamide/Brimonidine Fixed Combination BID Compared to Brinzolamide BID Plus Brimonidine BID in Subjects With Open-Angle Glaucoma (OAG) or Ocular Hypertension (OHT)treatment3completed
NCT00657579
Safety and Efficacy Study of DE-104 Ophthalmic Solution to Treat Open-Angle Glaucoma or Ocular HypertensionNo drug interventionsNot Available2completed
NCT06523751
Trabeculopuncture as Predictive Test for the Success of Ab Interno TrabeculectomyNo drug interventionsdiagnosticNot Availablerecruiting
NCT06230393
An Extension Trial for Patients With Open-Angle Glaucoma Who Participated in the DF6-CL-20-01 Protocol.No drug interventionsNot AvailableNot Availablenot_yet_recruiting
NCT06152861
Travoprost Ophthalmic Topical Cream for Open-angle Glaucoma or Ocular Hypertensiontreatment2recruiting
NCT05938699
Aqueous Humor Dynamics of NCX 470 Ophthalmic Solutionbasic_science2 / 3recruiting
NCT05309811
Effect of Repeated Low-Level Red-Light Therapy on Visual Field Damage in Primary Open-angle GlaucomaNo drug interventionstreatmentNot Availableunknown_status
NCT05273385
Efficacy of the Nanodropper Device on Intraocular Pressure in Patients With GlaucomaNo drug interventionshealth_services_researchNot Availablerecruiting
NCT05160805
A Phase 1b Study of ONL1204 Ophthalmic Solution in Patients With Progressing Open Angle Glaucomatreatment1active_not_recruiting
NCT04773106
Long-term Safety and Performance of the ARGOS-SC Suprachoroidal Pressure Sensor System in Patients With Glaucoma Underwent Non-penetrating Glaucoma SurgeryNo drug interventionsdiagnosticNot Availableunknown_status
NCT04758598
The Effects of DSLT and SLT on the Corneal Endothelium: A GLAUrious Trial Sub-StudyNo drug interventionsdiagnosticNot Availablecompleted
NCT04761705
Safety and Efficacy Study of JV-GL1 in Patients With Open-Angle Glaucoma or Ocular Hypertensiontreatment1 / 2suspended
NCT04524416
MINIject Global Long-Term Follow-up StudyNo drug interventionsNot AvailableNot Availablerecruiting
NCT04503356
OMNI in Open-angle Glaucoma TreatmentNo drug interventionstreatmentNot Availableunknown_status
NCT04475900
Computer-aided Diagnosis of Ocular Diseases Based on Corneal BiomechanicsNo drug interventionsNot AvailableNot Availablecompleted
NCT04014933
Reproducibility of Blood Flowmetry in Human Retina Using the Nidek Laser Speckle Flowgraphy LSFG-NAVI SystemNo drug interventionsNot AvailableNot Availablecompleted
NCT03210571
Clinical Investigation of the eyeWatch Glaucoma Drainage DeviceNo drug interventionstreatmentNot Availablecompleted
NCT05335122
A Study to Evaluate the Efficacy and Safety of OTX-TIC (Travoprost) Intracameral Implant for Patients With Open-angle Glaucoma (OAG) or Ocular Hypertension (OHT)treatment2active_not_recruiting
NCT05333419
Study of a Latanoprost Ocular Implant for Treatment of Open Angle Glaucoma or Ocular Hypertension.treatment1completed
NCT02438319
Automatic vs. Manual Optic Disc PlanimetryNo drug interventionsNot AvailableNot Availablewithdrawn
NCT02295358
The Effect of Omega-3 Fatty Acid Supplementation on Intraocular Pressure & Ocular SurfaceNo drug interventionsNot AvailableNot Availablewithdrawn
NCT02053298
Impact of Timolol/Dorzolamide Therapy on Autoregulation in Glaucoma Patientsbasic_science4completed
NCT02057575
Study Assessing Safety and Efficacy of PG324 Ophthalmic Solution in Patients With Elevated Intraocular Pressuretreatment2completed
NCT01886456
IOP Lowering Effect of PLT Versus SLT in Naiv OAG PatientsNo drug interventionstreatmentNot Availableunknown_status
NCT01802463
Study on Ocular Blood Flow and the Orbital Cerebrospinal Fluid Pressure in GlaucomaNo drug interventionsNot AvailableNot Availablecompleted
NCT01788319
Micropulse Laser Trabeculoplasty (532nm) Versus Conventional Laser Trabeculoplasty (532nm)No drug interventionstreatmentNot Availablecompleted
NCT01789736
A Study Assessing PG286 Ophthalmic Solution, 0.5% Compared to Its Individual Components for 28 Daystreatment2completed
NCT01794442
Study on the Oxygen Saturation in Pulsating and Non-pulsating Central Retinal VeinsNo drug interventionsNot AvailableNot Availableunknown_status
NCT01779778
Diurnal and Nocturnal Effect of Travatan With SofZia Preservative on Intraocular Pressure and Ocular Perfusion PressureNo drug interventionsNot AvailableNot Availablecompleted
NCT01645319
Comparative Effectiveness of Treatment Strategies for Primary Open-Angle GlaucomaNo drug interventionsNot AvailableNot Availablecompleted
NCT01528787
Study of AR-13324 in Patients With Elevated Intraocular Pressuretreatment2completed
NCT01452009
Three Month Safety and Efficacy Study of TRAVATAN® Versus Travoprost Ophthalmic Solution, 0.004%treatment3withdrawn
NCT01391247
Validation of Retinal Oximetry in Glaucoma Patients: a Structural and Functional CorrelationNo drug interventionsNot AvailableNot Availablecompleted
NCT01212861
Surgical Treatment of Refractory Open Angle GlaucomaNo drug interventionstreatmentNot Availablecompleted
NCT00941525
Central Corneal Thickness and 24-hour Fluctuation of Intraocular Pressurebasic_science4completed
NCT00912470
Progressive Open Angle Glaucoma (OAG) and Ocular Blood FlowNo drug interventionsdiagnosticNot Availablewithdrawn
NCT00912054
DuoTrav APS Versus XALACOM® in Ocular Surface Healthtreatment3terminated
NCT00621335
A Investigator Masked Parallel Comparison of Tolerability of Combigan and CosoptNo drug interventionsNot AvailableNot Availablecompleted
NCT00478036
Comparing Acular LS and Pred Forte in Reducing Post-selective Laser Trabeculoplasty Anterior Chamber Flare and CellstreatmentNot Availableterminated
NCT04060758
Open Label, Sequential-dose Study of PA5108 Latanoprost FA SR Ocular Implant for Mild-moderate Glaucomatreatment1active_not_recruiting
NCT00293787
A Study of Glaucoma Therapy to Treat Open-Angle Glaucoma or Ocular Hypertensiontreatment3completed
NCT01312454
Safety and Intraocular Pressure (IOP) Lowering Effect of AL-59412Ctreatment2terminated
NCT00047554
Study of TRAVATAN in Subjects With Iris Pigmentation ChangesNot AvailableNot Availableterminated
NCT00288951
Phase III Safety and Efficacy Study to Evaluate a Glaucoma Therapy in Open-Angle Glaucoma or Ocular Hypertension PatientsNo drug interventionstreatment3completed
NCT01510145
Efficacy of Changing to TRAVATAN® From Prior Therapytreatment4completed
NCT00698945
Comparison of Istalol™ 0.5% QD (Timolol Maleate/Sorbitol Complex, ISTA Pharmaceutical) to Brimonidine Tartrate 0.1% BID as Adjunctive Therapy to Latanoprost 0.005% in Adults With Ocular Hypertension (OHT) or Open-Angle Glaucoma (OAG)treatment4completed
NCT05822245
A Study of PER-001 in Participants With Open-Angle GlaucomaNo drug interventionstreatment1 / 2recruiting
NCT05411198
Study to Assess Change in Disease Activity and Adverse Events of Ab Externo Approach for Glaucoma Gel Stent (XEN45) Implantation In Participants Aged 45 Years or Older With Open-Angle GlaucomaNo drug interventionstreatment3recruiting
NCT01279083
Safety and Efficacy Trial to Treat Open-Angle Glaucoma or Ocular Hypertensiontreatment1 / 2completed
NCT00293761
A Study of Glaucoma Therapy to Treat Open-Angle Glaucoma or Ocular Hypertensiontreatment3completed
NCT00047528
Phase 3 Study to Evaluate IOP Lowering Therapy in Open Angle Glaucoma and Ocular Hypertension C-02-41No drug interventionstreatment3completed
NCT00047593
Phase 3 Study Comparing IOP Lowering in OAG or OH in Japanese Subjects C-01-98No drug interventionstreatment3completed
NCT02730871
Safety and Efficacy of SIMBRINZA® BID as an Adjunctive to DUOTRAV®treatment4terminated
NCT01369771
The Effects of Preservative-free Prostaglandin Eye Drops in Sign and Symptoms on the Eyes of Patients With Glaucomatreatment4completed
NCT00761709
Safety and Intraocular Pressure (IOP)-Lowering Efficacy of AL-39256 in Patients With Open-Angle Glaucoma or Ocular Hypertensiontreatment2completed
NCT00620256
Adjunctive Study of AL-37807 Ophthalmic Suspensiontreatment2completed
NCT00047515
Phase 3 Study to Evaluate IOP Lowering Therapy in Open Angle Glaucoma and Ocular Hypertension C-01-69No drug interventionstreatment3completed
NCT01510132
Travacom Post Marketing Surveillance Studytreatment4withdrawn
NCT00000132
Early Manifest Glaucoma Trial (EMGT)treatment3unknown_status
NCT00451152
Safety and Efficacy of Anecortave Acetate in Patients With Open-Angle Glaucomatreatment2completed
NCT00293800
A Study of Glaucoma Therapy to Treat Open-Angle Glaucoma or Ocular Hypertensiontreatment3completed
NCT01978600
Evaluation of Intraocular Pressure Using Simbrinza™ in Patients With Open-Angle Glaucoma or Ocular Hypertensiontreatment4completed
NCT00798759
Examination of Ocular Surface Effects With Administration of Travatan Z and XALATANtreatment4completed
NCT00705770
A Multi-Dose Study With a Treatment for Open-Angle Glaucomatreatment2 / 3withdrawn
NCT00716742
Safety and Efficacy Study of Bimatoprost, Latanoprost, and Travoprost in Patients With Elevated Intraocular Pressure (IOP) and Open-angle Glaucoma (OAG)Not AvailableNot Availablecompleted
NCT02014142
A Phase 2 Single-Masked, Randomized Study of Latanoprost PPDS in Ocular Hypertension or Open-Angle Glaucomatreatment2completed
NCT02873806
Two Trabecular Micro-bypass Stents & Postoperative Travoprost to Treat Glaucoma Subjects on Two Hypotensive Agentstreatment4completed
NCT00047606
Phase 4 Study Comparing IOP Lowering in OAG or OH in Caucasian or Japanese Subjects C-02-32No drug interventionstreatment4terminated
NCT00828906
DuoTrav® Eye Drops As Replacement Therapy Programtreatment4completed
NCT05338606
Expanded Access to Bimatoprost (Durysta)Not AvailableNot Availableavailable
NCT00000149
Collaborative Initial Glaucoma Treatment Study (CIGTS)No drug interventionstreatment3unknown_status
NCT02742649
A Study to Evaluate Efficacy and Safety of a Fixed Combination Ocular Insert in Participants With Open-angle Glaucoma or Ocular Hypertensiontreatment1 / 2completed
NCT02984813
Safety and Efficacy of Anti-Oxidants and Anti-inflammatory Agents in Glaucoma and Diabetic RetinopathyNo drug interventionsprevention1terminated
NCT00788541
A Dose-Volume Study of a Treatment for Elevated IOP Due to Open-Angle Glaucoma or Ocular Hypertensionprevention2terminated
NCT00397241
24-hour Study of Dorzolamide/Timolol and Latanoprost/Timolol Fixed Combinationstreatment4completed
NCT00047541
Phase 3 Study to Evaluate IOP Lowering Therapy in Open Angle Glaucoma and Ocular Hypertension C-01-70No drug interventionstreatment3completed
NCT00691717
Anecortave Acetate Safety in Patients With Open-Angle Glaucoma or Ocular Hypertensiontreatment2 / 3completed
NCT03267134
Hydrus Microstent for Refractory Open-Angle GlaucomaNo drug interventionstreatmentNot Availablecompleted
NCT00856622
A Study Demonstrating The Effect Of Latanoprost In Combination With Timolol, Latanoprost Alone And Timolol Alone On Eye Pressure In Open Angle Glaucoma Or Ocular Hypertension In Patientstreatment3completed
NCT01749930
Comparing the Safety and Efficacy of BOL-303259-X Ophthalmic Solution With Timolol Maleate Ophthalmic Solution in Subjects With Open-Angle Glaucoma or Ocular Hypertensiontreatment3completed
NCT00637130
Safety and Intraocular Pressure (IOP) Lowering Efficacy of Low Dose Travoprosttreatment2completed
NCT02410148
aICP in Glaucoma and PapilledemaNo drug interventionsdiagnosticNot Availableunknown_status
NCT04499248
AGN-193408 SR in the Treatment of Open-angle Glaucoma or Ocular HypertensionNo drug interventionstreatment1 / 2recruiting
NCT06577857
Inferonasal MIMS® Procedure: Long-Term Follow-Up Extension StudyNo drug interventionsNot AvailableNot Availablerecruiting
NCT06455683
The A D A G I O StudyNo drug interventionsNot AvailableNot Availablenot_yet_recruiting
NCT06441643
Next Generation Rocklatantreatment2not_yet_recruiting
NCT06246136
Comparative Effectiveness and Safety of ELIOS in Patients With Open-Angle Glaucoma Undergoing Cataract SurgeryNo drug interventionstreatmentNot Availablerecruiting
NCT05506423
Study of the CycloPen Micro-Interventional System and Long-Term Clinical OutcomesNo drug interventionsNot AvailableNot Availableenrolling_by_invitation
NCT05280366
STREAMLINE®SURGICAL SYSTEM Compared to iStent Inject W® in Patients With Open-Angle GlaucomaNo drug interventionstreatmentNot Availablerecruiting
NCT04911387
iCare® Home vs Goldmann Applanation TonometryNo drug interventionsNot AvailableNot Availablecompleted
NCT04352660
Subconjunctival Versus Direct Mitomycin C in Trabeculectomytreatment4completed
NCT04360174
CLN-0045: Safety, and Efficacy of OTX-TIC in Participants With Open Angle Glaucoma or Ocular HypertensionNo drug interventionstreatment1completed
NCT06313749
Safety and Effectiveness of Minimally Invasive Micro Sclerostomy (MIMS®) to Reduce Intraocular Pressure in Open-Angle Glaucoma Which is Not Controlled Despite PolypharmacyNo drug interventionstreatmentNot Availablerecruiting
NCT04202510
IOP and Medication Reduction in MIGS ProceduresNo drug interventionstreatmentNot Availablewithdrawn
NCT04188015
Study of ANX007 in Participants With Primary Open-angle GlaucomaNo drug interventionstreatment1completed
NCT03861169
Study of OMNI System in OAG (GEMINI)No drug interventionstreatmentNot Availablecompleted
NCT03875911
Comparing Preoperative Injection of Mitomycin-C vs. Intraoperative Injection of Mitomycin-C vs. Topical Application of Mitomycin-C (Conventional Use) in Trabeculectomytreatment4terminated
NCT03844945
Efficacy and Systemic Safety of Netarsudil 0.01%, 0.02%, 0.04% Relative to Placebo in Subjects With Open-angle Glaucoma or Ocular Hypertension in Japantreatment2completed
NCT03548805
Ologen® Collagen Matrix Versus Mitomycin-C in Patients With Juvenile-onset Open Angle GlaucomaNo drug interventionstreatmentNot Availablecompleted
NCT03201354
Efficacy and Safety of the ExPRESS Implant Versus Deep Sclerectomy in Combined SurgeryNo drug interventionstreatmentNot Availablecompleted
NCT03193736
MINIject in Patients With Open Angle Glaucoma Uncontrolled by Topical Hypotensive MedicationsNo drug interventionstreatmentNot Availablecompleted
NCT05583591
Combined Phacoemulsification With iStent Inject W Versus Hydrus for Mild to Moderate Open Angle GlaucomaNo drug interventionstreatmentNot Availablerecruiting
NCT05089474
A First in Human Clinical Trial to Evaluate the Safety and Effectiveness of the STREAMLINE SURGICAL SYSTEM in Patients With Open-Angle GlaucomaNo drug interventionstreatmentNot Availablecompleted
NCT05876936
Prospective, Open Label Study to Assess 24hs IOP Recorded With Triggerfish® in Patients With OAG Before and After DSCINo drug interventionspreventionNot Availableterminated
NCT04427995
Standalone OMNI Surgical System for Open-angle GlaucomaNo drug interventionsNot AvailableNot Availableterminated
NCT03160690
Changes in Choroidal Thickness After Non Penetrating Deep SclerectomyNo drug interventionsNot AvailableNot Availableunknown_status
NCT03374553
MINIject 636 in Patients With Open Angle Glaucoma Uncontrolled by Topical Hypotensive MedicationsNo drug interventionstreatmentNot Availablecompleted
NCT03284853
Safety and Efficacy Study of PG324 (Netarsudil/Latanoprost 0.02% / 0.005%) Ophthalmic Solution Compared to GANFORT® Ophthalmic Solution in Open Angle Glaucoma or Ocular Hypertensiontreatment3completed
NCT02784249
A Comparison of Two Ab Interno Procedures in the Treatment of Glaucoma in Patients Undergoing Cataract ExtractionNo drug interventionstreatmentNot Availablecompleted
NCT02874846
Nocturnal/Diurnal Intraocular Pressure-Lowering Effect of Netarsudil Ophthalmic Solutiontreatment2completed
NCT02868190
Two Second-Generation Trabecular Micro-bypass Stents to Treat Glaucoma Subjects on One Hypotensive MedicationNo drug interventionstreatment4completed
NCT02914509
Phase 3 Study Evaluating Safety and Efficacy of OTX-TP in Subjects With OAG or OHTtreatment3completed
NCT02713152
Prevalence of Obstructive Sleep Apnoea in GlaucomaNo drug interventionsNot AvailableNot Availablecompleted
NCT02448875
Clinical Evaluation of Visco-Assisted CyPass® Micro-Stent Implantation in Patients With Open Angle GlaucomaNo drug interventionstreatmentNot Availablecompleted
NCT02434250
Selective Laser Trabeculoplasty After Failed Phacoemulsification With Eximer Laser TrabeculectomyNo drug interventionstreatmentNot Availablecompleted
NCT02628223
180 Degree vs. 360 Degree Selective Laser Trabeculoplasty as Initial Therapy for GlaucomaNo drug interventionstreatmentNot Availablecompleted
NCT02272569
STARflo European Safety and Efficacy StudyNo drug interventionstreatmentNot Availablecompleted
NCT02165631
The Diurnal and Nocturnal Effect of Simbrinza and Timolol on Intraocular Pressure and Ocular Perfusion PressureNo drug interventionsNot AvailableNot Availablecompleted
NCT02003391
Efficacy of Travoprost/Timolol for Uncontrolled Intraocular Pressuretreatment4completed
NCT01983579
TF (SENSIMED Triggerfish) in Intraocular Anti-VEGF (Vascular Endothelial Growth Factor) InjectionNo drug interventionsdiagnostic4terminated
NCT01937299
Effect of SIMBRINZA® Suspension as an Added Therapy to TRAVATAN Z®treatment4completed
NCT01936389
A Prospective Study to Assess the Hypotensive Efficacy of Rho-Kinase Inhibitor AR-12286 Ophthalmic Solution 0.5% and 0.7% in Patients With Exfoliation Syndrome and Ocular Hypertension or GlaucomaNo drug interventionstreatment2completed
NCT01956942
Micropulse Laser Trabeculoplasty (MLT) Versus Selective Laser Trabeculoplasty (SLT) for Treatment of Open Angle GlaucomaNo drug interventionstreatmentNot Availablecompleted
NCT01937312
Effect of SIMBRINZA® Suspension as an Added Therapy to a Prostaglandin Analoguetreatment4completed
NCT01923714
Impact of a Tolerability Switch to Dorzolamide/Timolol Preservative-free Fixed Combination on Ocular Surface SymptomsNo drug interventionsNot AvailableNot Availablecompleted
NCT01840215
Study on the Impact of Ocular Anesthetic Procedures in Ocular Blood FlowNo drug interventionsNot AvailableNot Availablecompleted
NCT01840202
Ocular Blood Flow in Glaucoma Patients - the Leuven Eye StudyNo drug interventionsNot AvailableNot Availablecompleted
NCT01721707
Latanoprost/Brinzolamide BID Versus Latanoprost BID in Patients With OAG or OHtreatment3withdrawn
NCT01739244
Dose Finding Clinical Trial With SYL040012 to Evaluate the Tolerability and Effect on Intraocular Pressure in Subjects With Ocular Hypertension or Open Angle Glaucomatreatment2completed
NCT01726543
Safety and Efficacy of Canaloplasty and Non-penetrating Deep Sclerectomy With Phacoemulsification to Treat Glaucoma and CataractNo drug interventionstreatmentNot Availableunknown_status
NCT01731002
Study Comparing the Safety and Efficacy of AR-13324 to Latanoprost in Patients With Elevated Intraocular Pressuretreatment2completed
NCT01707381
BOL-303259-X With Timolol 0.5% in Subjects With Open-Angle Glaucoma or Ocular Hypertensiontreatment2completed
NCT01342406
Effects of Selective Laser Trabeculoplasty on Aqueous Humor DynamicsNo drug interventionsNot AvailableNot Availablecompleted
NCT01059162
Evaluation of OT-135P (IOPtiMateTM) : Beam Manipulating System for CO2 Laser Assisted Non-Penetrating Glaucoma SurgeryNo drug interventionstreatmentNot Availableunknown_status
NCT01055366
ELAZOP Switching Study in Koreatreatment4completed
NCT00947661
Efficacy and Safety of SPARC0912 and Reference0912 in Open Angle Glaucoma or Ocular HypertensionNo drug interventionstreatment3completed
NCT00892762
Travoprost APS Versus Xalatan® in Patient Reported Outcomes and Ocular Surface Healthtreatment3completed
NCT00848536
Efficacy Study of Travoprost APS Versus TRAVATANtreatment3completed
NCT00751127
A 6 Month Study Comparing Latanoprost With Timolol in Patients With Open Angle Glaucoma or Ocular Hypertensiontreatment3completed
NCT00751049
A Study of Open Angle Glaucoma or Ocular Hypertension in Patients Within the United Kingdomtreatment3completed
NCT00665756
Comparison of Efficacy Between Silicone Ahmed Glaucoma Valves and Second Trabeculectomy in Glaucoma PatientsNo drug interventionstreatmentNot Availableunknown_status
NCT00538590
Ologen Collagen Matrix Safety and Effective Comparison With Mitomycin-C(MMC) in Glaucoma Surgerytreatment4completed
NCT00545064
Dry Eye Study With Cosopt® Over 8 Weeks in Patients With Open-Angle Glaucoma or Ocular Hypertension (0507A-152)(COMPLETED)treatment4completed
NCT00539526
Evaluation of Hyperemia With the Use of Ocular Prostaglandin Analoguestreatment4completed
NCT00440336
Comparison of Efficacy of Two Groups of Glaucoma Drops (Xalatan vs.Cosopt) in Reducing Eye Pressure Following Laser (SLT)Treatment in the Management of Glaucoma.health_services_researchNot Availableunknown_status
NCT00430287
Does the Optic Disc Grading Done Visually by Your Doctor Agree With Optic Nerve Testing Which is Done by Machines?No drug interventionsNot AvailableNot Availablecompleted
NCT00277498
A 12-week, Randomized, Double-masked, Parallel Group Comparison of Evening Dosing With Xalacom in Subjects With Glaucomatreatment3completed
NCT00121147
Additivity Study: Additive Effect on Eye Pressure of Azopt and Alphagan P to TravatantreatmentNot Availablecompleted
NCT00001161
Abnormalities of the Eye's Anterior Chamber, Iris, Cornea and LensNo drug interventionsNot AvailableNot Availablecompleted
NCT00141882
Memantine in Patients With Chronic Glaucomatreatment3completed
NCT01026831
Preservative-Free MK2452 (Tafluprost) for Open-Angle Glaucoma/Ocular Hypertension (MK2452-001)(COMPLETED)treatment3completed
NCT00815373
The Effects of Cosopt® Vs Xalacom® on Ocular Hemodynamics and Intraocular Pressure (IOP) in Primary Open-angle Glaucoma (POAG)Not AvailableNot Availablewithdrawn
NCT01493427
Efficacy of Changing to TRAVATAN® From Prior Therapytreatment4completed
NCT02348476
A Study of Simbrinza™ Therapy in Patients With Open-Angle Glaucoma or Ocular HypertensionNo drug interventionsNot AvailableNot Availablecompleted
NCT01511094
Goniocurettage as First Choice of Surgical Treatment in Chronic Open-Angle Glaucoma: Outcomes and ComplicationsNo drug interventionstreatment2 / 3unknown_status
NCT00690794
Travatan Z in Ocular Surface Health in Patients With Open-Angle Glaucoma or Ocular Hypertensiontreatment3completed
NCT02207491
Double-masked Study of AR-13324 Ophthalmic Solution in Patients With Glaucoma or Ocular Hypertensiontreatment3completed
NCT01016691
Safety and Efficacy of a Drug Delivery System in Glaucomatreatment2completed
NCT00596791
Ocular Signs and Symptoms in Glaucoma Patients Switched From Latanoprost 0.005% to Preservative Free Tafluprost Eye Dropstreatment3completed
NCT01781962
A Study of Quantitative Assessments of Angle Width in Chinese Patients With Open-angle Glaucoma and/or Ocular HypertensionNo drug interventionsNot AvailableNot Availableterminated
NCT02743780
A Three Part Study of MGV354 in Ocular Hypertension or GlaucomaNo drug interventionsother1 / 2completed
NCT04285580
A Phase 3b Study Evaluating the 24-Hour Intraocular Pressure Lowering Effect of Bimatoprost SR in Patients With Open-Angle Glaucoma or Ocular Hypertensiontreatment3completed
NCT03648229
African Glaucoma Laser Trialtreatment4withdrawn
NCT00061529
A Phase III Study of Brimonidine Tartrate Ophthalmic Solution, 0.15% in Patients With Open-Angle Glaucoma or Ocular Hypertensiontreatment3completed
NCT02928289
Randomized Study of the Safety and Effectiveness of the Sight Sciences VISCO™360 Viscosurgical System Versus SLT in Primary Open Angle Glaucoma (VISCO360 Study)No drug interventionstreatmentNot Availableterminated
NCT00527592
A Single Dose Comfort Comparison of Travatan Z in One Eye Versus Xalatan in the Opposite Eye in Patients With Primary Open-Angle Glaucoma or Ocular Hypertensiontreatment4completed
NCT00000144
Glaucoma Laser Trial (GLT) Glaucoma Laser Trial Followup Study (GLTFS)No drug interventionstreatment3completed
NCT01444040
Subjects With Open-angle Glaucoma, Pseudoexfoliative Glaucoma, or Ocular Hypertension Naïve to Medical and Surgical Therapy, Treated With Two Trabecular Micro-bypass Stents (iStent Inject) or Travoprosttreatment4completed
NCT00656240
To Investigate the Safety and Efficacy of DE-104 Ophthalmic Solution to Treat Open-Angle Glaucoma or Ocular HypertensionNo drug interventionsNot Available2completed
NCT00326040
A Study of the Glaukos Trabecular Micro-Bypass Stent in Refractory Open Angle Glaucoma SubjectsNo drug interventionstreatment4completed
NCT01426867
A Comfort Study of Brinzolamide 1% / Brimonidine 0.2% Fixed Combination, Brinzolamide 1% and Brimonidine 0.2%treatment2completed
NCT00527501
IOP Lowering Efficacy of Travoprost/Brinzolamide Fixed Combination Ophthalmic Suspension in Patients With Open-Angle Glaucoma or Ocular Hypertensiontreatment2completed
NCT01309204
Brinzolamide/Brimonidine Twice a Day (BID) Fixed Combination (FC) vs Brinzolamide BID Plus Brimonidine BID in Patients With Open Angle Glaucoma or Ocular Hypertensiontreatment3completed
NCT00862472
Safety and Efficacy Study of DuoTrav APS Versus DuoTravtreatment3withdrawn
NCT00471068
Study of Travatan and Cosopt in Primary Open-Angle Glaucoma or Ocular Hypertensiontreatment4terminated
NCT00721968
Safety and Efficacy of the GTS400 Stent in Conjunction With CataractNo drug interventionstreatment3completed
NCT00643669
24 Hour IOP Lowering Efficacy of AL-3789treatment2completed
NCT03891446
Long-term Safety and Efficacy Extension Trial of Bimatoprost SRtreatment3enrolling_by_invitation
NCT03904381
Efficacy and Safety of XEN® Gel Stent and Post-operative Management in Patients With Open Angle Glaucomahealth_services_research4active_not_recruiting
NCT04647214
18 Month Prospective Efficacy and Safety Study of Bimatoprost Intracameral Implant (DURYSTA)No drug interventionsNot AvailableNot Availablecompleted
NCT05821855
A Study to Evaluate Adverse Events and Change in Disease Activity With the XEN45 Glaucoma Treatment System Implantation In Adult Participants With Open-Angle Glaucoma in ChinaNo drug interventionstreatment4recruiting
NCT00273455
Lumigan Versus Cosopttreatment4completed
NCT00822055
Comparison of the Fixed Combinations of Brimonidine/Timolol and Dorzolamide/Timolol in Subjects With Open-Angle Glaucoma or Ocular Hypertensiontreatment4completed
NCT01453855
Travoprost 3-Month Safety and Efficacy Studytreatment3completed
NCT00804323
PASCAL TrabeculoplastyNo drug interventionstreatmentNot Availableterminated
NCT02419508
SIMBRINZA® Suspension BID as an Adjunctive to Prostaglandin Analogue (PGA)treatment4completed
NCT00481208
Diurnal Intraocular Pressure and Peripapillary Retinal Blood Flow in Medically Controlled Open-Angle GlaucomaNo drug interventionsNot AvailableNot Availablecompleted
NCT01568008
Observational Study of Lumigan® 0.01% for Treatment of Primary Open Angle Glaucoma (POAG) or Ocular Hypertension (OHT)Not AvailableNot Availablecompleted
NCT00650338
Safety and Efficacy Study of DE-104 Ophthalmic Solution to Treat Open-angle Glaucoma or Ocular Hypertensiontreatment2completed
NCT00823043
A Comfort Survey of Open-angle Glaucoma or Ocular Hypertension Patients Treated With 2 DrugsNot AvailableNot Availablecompleted
NCT00320203
Anecortave Acetate in Patients With Open-angle Glaucomatreatment2completed
NCT01157364
Safety and Efficacy of a New Ophthalmic Formulation of Bimatoprost in Patients With Open Angle Glaucoma and Ocular Hypertensiontreatment1 / 2completed
NCT01068964
Safety and Efficacy of Bimatoprost Timolol Ophthalmic Solution in Patients With Open Angle Glaucoma or Ocular HypertensiontreatmentNot Availablecompleted
NCT02207621
Evaluation of Netarsudil (AR-13324) Ophthalmic Solution in Patients With Glaucoma and Ocular Hypertensiontreatment3completed
NCT00287521
A Study of Glaucoma Therapy to Treat Open-Angle Glaucoma or Ocular Hypertensiontreatment2completed
NCT00326079
A Study of the Glaukos Trabecular Micro-bypass Stent in Open Angle Glaucoma Subjects 1 Stent Versus 2No drug interventionstreatment4unknown_status
NCT01298687
Divided Dose of TRAVATAN®treatment2completed
NCT00803387
Dry Eye and Irritation Comparison of Latanoprost With the Preservative Versus Travoprost Without PreservativeNot AvailableNot Availablecompleted
NCT00670033
Travoprost New Formulations in Patients With Open-Angle Glaucoma or Ocular Hypertensiontreatment2completed
NCT02674854
Double-masked Study of PG324 Ophthalmic Solution in Patients With Open-angle Glaucoma or Ocular Hypertensiontreatment3completed
NCT00872651
Travoprost 0.004%/Timolol 0.5% Versus Latanoprost 0.005%/Timolol in Chinese Patients With Open-Angle Glaucoma or Ocular Hypertensiontreatment3completed
NCT01310777
Brinzolamide/Brimonidine Twice a Day (BID) Fixed Combination (FC) vs Brinzolamide BID and Brimonidine BID in Patients With Open Angle Glaucoma or Ocular Hypertensiontreatment3completed
NCT00308945
Influence of Prostaglandins on Ocular Blood Flow in Glaucoma Patientstreatment4completed
NCT01444105
Open-angle Glaucoma Subjects on One Ocular Hypotensive Medication Randomized to Treatment With Two Trabecular Micro-bypass Stents or Selective Laser TrabeculoplastyNo drug interventionstreatmentNot Availablecompleted
NCT00672997
A Phase III Study of Travoprost/Timolol Combination in Patients With Open-Angle Glaucoma or Ocular Hypertensiontreatment3completed
NCT01306461
Tafluprost-Timolol Fixed Dose Combination Non-Inferiority Study Against Concomitant Administrationstreatment3completed
NCT03604328
Safety and Tolerability of a Prostaglandin Ocular Implant for Treatment of Open Angle GlaucomaNo drug interventionstreatment1completed
NCT01087671
Ocular Signs and Symptoms in Glaucoma Patients Switched From Latanoprost to Preservative Free Tafluprost Eye Dropstreatment3completed
NCT00314171
A Study of a Glaucoma Therapy to Treat Open-Angle Glaucoma or Ocular Hypertensiontreatment3completed
NCT01443988
Subjects With Open-angle Glaucoma, Pseudoexfoliative Glaucoma, or Ocular Hypertension Naïve to Medical and Surgical Therapy, Treated With Two Trabecular Micro-bypass Stents (iStent)or Travoprosttreatment4completed
NCT00304785
Latanoprost Versus Fotiltreatment4completed
NCT02558400
Double-masked Study of PG324 Ophthalmic Solution in Patients With Glaucoma or Ocular Hypertensiontreatment3completed
NCT04910100
Nebivolol 0.5, 1.0, or Timolol 0.5 Suspension Compared to Timolol 0.5 Solution to Treat Glaucoma/Ocular Hypertensiontreatment2completed
NCT00273442
Assessing Cosopt Switch Patientstreatment4completed
NCT01327599
Efficacy of Changing to DUOTRAV® From Prior Therapytreatment4completed
NCT00069706
Phase II Safety and Efficacy Study to Evaluate a Glaucoma Therapy in Open-angle Glaucoma or Ocular Hypertension Patientstreatment2completed
NCT00961649
Safety and Efficacy of Brinzolamide/Brimonidine Fixed Combinationtreatment2terminated
NCT01037036
A Study of the L-PPDS With Adjunctive Xalatan® Eye Drops in Subjects With OH or OAGtreatment2completed
NCT06498440
Efficacy of NSAID vs. Steroid-NSAID Combo Post-Selective Laser Trabeculoplasty: Phase 4, Single-Center RCTtreatment4not_yet_recruiting
NCT06214676
OCTA in Patients With Primary Open-angle GlaucomaNo drug interventionsNot AvailableNot Availablenot_yet_recruiting
NCT06061718
Travoprost Intraocular Implant in Conjunction With Cataract Surgerytreatment3active_not_recruiting
NCT05955118
Hydrus Microstent as a Quality of Life ConsiderationNo drug interventionsNot AvailableNot Availablerecruiting
NCT05269680
STAR-LIFE: a Post-market Registry on MINIjectNo drug interventionsNot AvailableNot Availablerecruiting
NCT05104294
Correlation Between Optical Coherence Tomography Angiography and Photopic Negative Response in Patients With GlaucomaNo drug interventionsNot AvailableNot Availablecompleted
NCT03756662
Performance and Safety of the ARGOS-SC01 Suprachoroidal Pressure Sensor in Patients With Glaucoma Undergoing Non-penetrating Glaucoma SurgeryNo drug interventionsdiagnosticNot Availablecompleted
NCT04445519
Phase 3 Trial of NCX 470 vs. Latanoprost in Subjects With Open-Angle Glaucoma or Ocular Hypertensiontreatment3completed
NCT03960866
Safety and Efficacy of Ophthalmic Phentolamine Mesylate in Glaucomatreatment2completed
NCT03750201
A Study to Assess an Automated Laser Device for Direct Selective Laser TrabeculoplastyNo drug interventionstreatmentNot Availablecompleted
NCT03611530
CoQun Study - (COQUN): a Study to Evaluate the Effects of CoQun in Patients Affected by Open-angle GlaucomaNo drug interventionsotherNot Availableterminated
NCT04630808
MRCT Evaluating NCX 470 vs. Latanoprost in Subjects With Open-Angle Glaucoma or Ocular Hypertensiontreatment3recruiting
NCT04700189
A FIH Trial of the STREAMLINE™ SURGICAL SYSTEMNo drug interventionstreatmentNot Availablecompleted
NCT05241938
PSLT Compared to Prostaglandin Analogue Eye DropsNo drug interventionstreatmentNot Availableunknown_status
NCT05456724
A Study to Investigate the Effect of IOP-lowering With TO-O-1001 Eye Drops in Healthy Subjects and in Patients With Open-Angle Glaucoma or Ocular HypertensionNo drug interventionstreatment1 / 2active_not_recruiting
NCT03450629
Evaluation of Safety and Efficacy of PDP-716treatment3completed
NCT05035394
Swedish Microinvasive Glaucoma Surgery Study (SMIGS)No drug interventionstreatmentNot Availableactive_not_recruiting
NCT03047239
TF for the Prediction of Visual Field ProgressionNo drug interventionsdiagnosticNot Availablewithdrawn
NCT02250612
SYL040012, Treatment for Open Angle Glaucomatreatment2completed
NCT02278614
Efficacy and Safety Assessment of T2347 Versus Xalacom® in Ocular Hypertensive or Glaucomatous Patientstreatment3completed
NCT02129673
A Phase 1/2 Multicenter, Randomized, Study to Evaluate the Safety and Efficacy of VS101 Subconjunctival Latanoprost Insert in Subjects With Open-Angle Glaucoma or Ocular Hypertensiontreatment1 / 2completed
NCT01895686
Comparison of Gonioscopy With Cirrus and VisanteNo drug interventionsNot AvailableNot Availablecompleted
NCT01887873
Safety of Hyaluronan Thiomer i.o. Implant During Combined Phacoemulsification - Non Penetrating Deep SclerectomyNo drug interventionstreatment1completed
NCT01484392
Determinants of Compliance With Glaucoma TherapyNo drug interventionsNot AvailableNot Availablecompleted
NCT01342094
DE-111 Against Timolol Ophthalmic Solution 0.5%treatment3completed
NCT01342081
DE-111 Against Tafluprost Ophthalmic Solution 0.0015% Alone and Concomitant Use of Tafluprost Ophthalmic Solution 0.0015% Plus Timolol Ophthalmic Solution 0.5%treatment3completed
NCT01229982
A Study Evaluating the Latanoprost Punctal Plug Delivery System (L-PPDS) in Subjects With Ocular Hypertension or Open-Angle Glaucomatreatment2completed
NCT00945958
Evaluation of Safety of SPARC0913 in Open Angle Glaucoma or Ocular HypertensionNo drug interventionstreatment3completed
NCT00901108
Trabectome Versus Trabeculectomy With Mitomycin C in Patients With Open Angle GlaucomaNo drug interventionstreatment3terminated
NCT00878917
Equivalence Study of Dorzolamide 2% Eye Drops Solutiontreatment3completed
NCT00844389
Near to Infrared (NIR) Light Neuroprotection in Glaucomatous Optic NeuropathyNo drug interventionstreatment0unknown_status
NCT00751062
A Study of Open Angle Glaucoma or Ocular Hypertension in Patients Within Scandinaviatreatment3completed
NCT00524758
Oculusgen (Ologen) Glaucoma MMC Control in Estoniatreatment3completed
NCT00443924
Study of INS115644 Ophthalmic Solution in Subjects With Ocular Hypertension or GlaucomaNo drug interventionstreatment1completed
NCT00362622
Determinants of Compliance With Glaucoma TherapyNo drug interventionsNot AvailableNot Availablecompleted
NCT02325518
Comparison of Intraocular Pressure (IOP)-Lowering Efficacy and Safety of AZORGA® Ophthalmic Suspension and COSOPT® Ophthalmic SolutionNot Available4completed
NCT00069719
Phase II Safety and Efficacy Study to Evaluate a Glaucoma Therapy in Open-Angle Glaucoma or Ocular Hypertension PatientsNo drug interventionstreatment2completed
NCT00761319
Phase III Clinical Trial of TRAVATAN Z in Ocular Surface Healthtreatment3completed
NCT01297517
Efficacy and Safety Study of Brinzolamide 1%/Brimonidine 0.2% vs. Brinzolamide 1% and Brimonidine 0.2%treatment3completed
NCT01464424
Assessment of Intraocular Pressure (IOP) Control in Subjects With Open-Angle Glaucoma or Ocular Hypertension Treated With Travoprost 0.004% (TRAVATAN® Z) or Bimatoprost 0.01% (LUMIGAN®)treatment4completed
NCT01357616
Fixed Combination Brinzolamide 1%/Timolol 0.5% Versus Brinzolamide 1% + Timolol 0.5% in Open-Angle Glaucoma or Ocular Hypertensiontreatment3completed
NCT00314158
A Study of a Glaucoma Therapy to Treat Open-Angle Glaucoma or Ocular Hypertensiontreatment3completed
NCT00759239
Phase IV Randomised Double-masked Clinical Trial: Assessing Morning Versus Evening Dosing of a Fixed Dose Combination of Travoprost 0.004% / Timolol Maleate 0.5% in Patients With Primary Open-angle Glaucoma or Ocular Hypertensiontreatment4completed
NCT00691639
Collection of Blood Specimens From Patients in AL-3789 Studies for Elevated Intraocular Pressure (IOP)No drug interventionsNot AvailableNot Availablecompleted
NCT00760539
Safety and Efficacy of Travoprost/Timolol BAC-freetreatment3completed
NCT01485822
A Multicenter Study of the Pigmentation in the Trabecular Meshwork After Two Years of Treatment With TRAVATAN 0.004% Ophthalmic SolutionNot AvailableNot Availableterminated
NCT04499157
Effect of MEMOPTIC on Visual Field of Patients Followed for a Chronic Open-angle GlaucomaNo drug interventionstreatmentNot Availablerecruiting
NCT00326066
A Study of the iStent in Combo With Cataract Surgery in Newly Diagnosed Open Angle Glaucoma or OH Patients.No drug interventionstreatmentNot Availablecompleted
NCT02558374
Double-masked Study of Netarsudil (AR-13324) Ophthalmic Solution in Subjects With Glaucoma or Ocular Hypertensiontreatment3completed
NCT06267274
A Randomized, Double-blind, Parallel-group, Two-arm, Multiple Dose, Multicenter, Bioequivalence Study With Clinical Endpoint in the Treatment of Subjects With Chronic Open-angle Glaucoma or Ocular Hypertension in Both Eyestreatment1recruiting
NCT01297920
Three Month Efficacy/Safety Study With a 3-Month Safety Extension of Brinzolamide 1%/Brimonidine 0.2% vs. Brinzolamide 1% or Brimonidine 0.2%treatment3completed
NCT01174420
Comparative Study of Ologen Collagen Matrix Versus Mitomycin-C in Trabeculectomy: A Study in GermanypreventionNot Availableunknown_status
NCT03850782
Evaluation of the Duration of Effect of Bimatoprost SR in Participants With Open-Angle Glaucoma or Ocular Hypertensiontreatment3active_not_recruiting
NCT00372931
A Phase II Study of AL-37807 to Treat Open-Angle Glaucoma or Ocular HypertensionNo drug interventionstreatment2completed
NCT01292460
Tafluprost-Timolol Preservative-free Fixed Dose Combination (FDC) Superiority Study Against MonotherapiesNo drug interventionstreatment3completed
NCT00868894
Safety and Efficacy Study of DE-104 Ophthalmic Solution to Treat Open-angle Glaucoma or Ocular Hypertensiontreatment1 / 2completed
NCT00273429
Cosopt Versus Xalatantreatment4completed
NCT00887029
A 12 Week Comparison of DuoTrav and Xalacom in Open-Angle Glaucomatreatment4completed
NCT00326092
A Study of a Glaucoma Therapy to Treat Open-Angle Glaucoma or Ocular Hypertensiontreatment2completed
NCT01455467
Open-angle Glaucoma Subjects on One Topical Hypotensive Medication Randomized to Treatment With One or Two Trabecular Micro-bypass Stents in Conjunction With Cataract SurgeryNo drug interventionstreatmentNot Availablecompleted
NCT01415401
Efficacy and Tolerability of AZARGA® as Replacement Therapy in Patients on COMBIGAN® Therapy in Canadatreatment4completed
NCT01749904
Comparing Safety and Efficacy of BOL-303259-X With Timolol Maleate in Subjects With Open-Angle Glaucoma or Ocular Hypertensiontreatment3completed
NCT00508469
Adherence Assessment With Travalert Dosing Aidtreatment4completed
NCT00918346
Pharmacodynamics of Tafluprost 0.0015% Eye Drops: a Comparison Between the Preserved and Unpreserved Formulationtreatment3completed
NCT00273481
Cosopt Versus Xalacomtreatment4completed
NCT00822081
Comparison of the Fixed Combinations of Brimonidine/Timolol and Dorzolamide/Timolol in Subjects With Open-Angle Glaucoma or Ocular Hypertensiontreatment4completed
NCT02638181
The Expression of Matrix Metalloproteinase 13, Tissue Inhibitor of Metalloproteinases 3, and Calcium-sensing Receptor in Human Trabecular MeshworkNo drug interventionsbasic_scienceNot Availablecompleted
NCT00457795
24-hour IOP-lowering Effect of Brimonidine 0.1%treatment4completed
NCT01340014
Patient Preference Comparison of AZARGA Versus COSOPTtreatment4completed
NCT00326014
A Study of the Trabecular Micro-Bypass Stent in Combination With Cataract Surgery in Open Angle Glaucoma Subjects.No drug interventionstreatment4completed
NCT01487655
Waveform Analysis of the Doppler Curve of Ophthalmic Arteries in Glaucoma PatientsNo drug interventionsNot AvailableNot Availablecompleted
NCT00168350
Memantine in Patients With Chronic Glaucomatreatment3completed
NCT03488550
Single-dose Study of ANX007 in Participants With Primary Open-angle GlaucomaNo drug interventionstreatment1completed
NCT02179008
Multi-center Phase II Study Assessing the Safety and Efficacy of DE-117 Ophthalmic Solution in Subjects With Primary Open-angle Glaucoma or Ocular Hypertensiontreatment2completed
NCT04944290
To Compare the Efficacy and Safety of Perrigo's Product to an FDA Approved Product for the Treatment of Glaucoma or Ocular Hypertension in Both Eyestreatment3completed
NCT00283764
Safety And Efficacy Of Xalatan Delivered Using Either A Conventional Dropper Bottle or A Delivery Devicetreatment3withdrawn
NCT00470964
Titanium-Sapphire Laser Trabeculoplasty in Glaucoma: A Randomized Study Comparing Titanium-Sapphire With Argon Laser Trabeculoplasty in Open-Angle Glaucoma PatientsNo drug interventionsNot AvailableNot Availablecompleted
NCT03804684
visuALL Field Analyzer (vFA) Compared to Standard Humphrey Automated PerimetryNo drug interventionsdiagnosticNot Availablecompleted
NCT05039684
Inflammatory Biomarkers in Ocular Surface in Primary Open Angle Glaucoma or Ocular Hypertension Under Topical ProstaglandinsNo drug interventionsNot AvailableNot Availablerecruiting
NCT04452279
Ocular Surface Disease Changes After iStent or iStent Inject Implantation With PhacoemulsificationNo drug interventionstreatmentNot Availablecompleted
NCT00804648
Patient Satisfaction With Timolol in Subjects With Open-Angle Glaucoma or Ocular Hypertensiontreatment4completed
NCT00317577
Study of Medical Treatment of Low-Pressure (Normal Tension) Glaucomatreatment2completed
NCT00140049
A 12week, Randomized, Evaluator-Masked, Parallel Group Comparing Evening Dosing Of Xalacom Vs Cosopt In Subj W/ Glaucomatreatment4completed
NCT02507687
Comparison of Bimatoprost Sustained Release (SR) to Selective Laser Trabeculoplasty (SLT) in Adults With Open-Angle Glaucoma or Ocular Hypertensiontreatment3completed
NCT03452033
H-1337 Ophthalmic Solution Phase 1/2No drug interventionstreatment1 / 2completed
NCT05593354
MicroPulse TLT - UK StudyNo drug interventionsNot AvailableNot Availablenot_yet_recruiting
NCT03325751
Visual Field Defect Estimation Using Sequentially Optimized Reconstruction Strategy on Healthy and Glaucoma SubjectsNo drug interventionsNot AvailableNot Availablecompleted
NCT01646151
A Study Comparing IOP-Lowering Treatments to Bimatoprost in Patients With Primary Open Angle Glaucoma or Ocular HypertensionNot AvailableNot Availablecompleted
NCT00159653
A 12-Week, Randomized, Double-Masked, Parallel Group Comparison Of Evening Dosing With Xalacom In Subjects With Glaucomatreatment3completed
NCT06369077
How Much Does Reduced Dosing of Latanoprost and Dorzolamide-timolol Affect Pressure?treatment4terminated
NCT04214847
The Outcome of Ahmed Glaucoma Valve in Difficult Glaucoma CasesNo drug interventionstreatmentNot Availablecompleted
NCT04430647
Phaco-UCP Versus Phaco Alone for OAG and CataractNo drug interventionstreatmentNot Availablecompleted
NCT05710198
Efficacy of Citicoline Eye Drops 2% on Visual Field Preservation in Patients With Open Angle Glaucomaprevention3recruiting
NCT04624698
iStent Inject New Enrollment Post-Approval StudyNo drug interventionstreatmentNot Availableactive_not_recruiting
NCT06058598
Exercise Training in Patients With GlaucomaNo drug interventionstreatmentNot Availablerecruiting
NCT01628588
Lumigan® in Patients With Primary Open Angle Glaucoma (POAG) or Ocular Hypertension (OHT)Not AvailableNot Availablecompleted
NCT03689088
Sensing Contact Lens-based Device for 24-hour Monitoring of Intraocular PressureNo drug interventionsdevice_feasibilityNot Availablecompleted
NCT04888156
Impact of Self-tonometry on Glaucoma Treatment Decision.No drug interventionsNot AvailableNot Availablecompleted
NCT00693485
Safety and Effects of Brimonidine Intravitreal Implant in Patients With Glaucomatous Optic Neuropathytreatment2completed
NCT03255785
Open-Angle Glaucoma Subjects With Cataract Treated With Cataract Surgery Plus One iStent and One iStent SupraNo drug interventionstreatmentNot Availablecompleted
NCT04624685
iStent Inject Trabecular Micro-Bypass System Continuation Post-Approval StudyNo drug interventionsNot AvailableNot Availableunknown_status
NCT04234932
Short-term Effect of Rho-kinase Inhibitor on Retinal Circulationtreatment0unknown_status
NCT01987752
Safety and Efficacy of Combigan® Ophthalmic Solution in KoreaNot AvailableNot Availablecompleted
NCT00781300
Intraocular Pressure With Loteprednol and Dexamethasonetreatment4completed
NCT04703959
Glaucoma and Sleep QualityNo drug interventionsNot AvailableNot Availableunknown_status
NCT04215575
Baerveldt (BGI) Valve Versus Ahmed(AGV) Valve in Management of Difficult Glaucoma CasesNo drug interventionstreatmentNot Availablecompleted
NCT02754570
The Diurnal and Nocturnal Effect of Pilocarpine on Intraocular Pressure and Ocular Perfusion PressuretreatmentNot Availablecompleted
NCT01594970
A Safety and Efficacy Study of Bimatoprost 0.01% in Primary Open-Angle Glaucoma (POAG) or Ocular Hypertension (OH)treatment4completed
NCT00051142
A Safety and Efficacy Study of Travoprost 0.004% Compared to Latanoprost 0.005% in Patients With Open-Angle Glaucoma (OAG) or Ocular Hypertension (OHT)treatment3completed
NCT02959242
Dresden Glaucoma and Treatment Study (DGTS)No drug interventionsNot AvailableNot Availablerecruiting
NCT03373942
The Effect of Pseudoexfoliation on Choroidal Thickness in Open Angle GlaucomaNo drug interventionsNot AvailableNot Availablecompleted
NCT01217606
Safety and Efficacy of Triple Combination Therapy in Patients With Primary Open-Angle Glaucoma or Ocular Hypertensiontreatment3completed
NCT04890106
Bioequivalence Study With Clinical Endpoint Comparing Bimatoprost Ophthalmic Solution 0.01% to LUMIGAN® In The Treatment of Chronic Open-Angle Glaucomatreatment3completed
NCT03267849
Lamina Cribrosa Depth Change With Change in Eye PressureNo drug interventionsdiagnosticNot Availablerecruiting
NCT03187418
Treatment Outcomes of MicroPulse Trans-scleral Cyclophotocoagulation in Uncontrolled GlaucomaNo drug interventionstreatmentNot Availablecompleted
NCT05159817
Study of an Interposition Supraciliary Implant in Patients With Open Angle GlaucomaNo drug interventionsNot AvailableNot Availableactive_not_recruiting
NCT04038034
Valuation of the Antioxidant and Neuroprotective Effects of CoQ10-MINIACTIVES® (COQUN® OS) in Patients Affected by Primary Open Angle GlaucomaNo drug interventionstreatmentNot Availableunknown_status
NCT02003534
A Study of 0.15% Brimonidine Tartrate in Patients With Primary Open Angle Glaucoma and Ocular Hypertensiontreatment4completed
NCT04770324
Study of a Novel Interposition Supraciliary Implant in Patients With Open Angle Glaucoma (SAFARI 2)No drug interventionstreatmentNot Availableactive_not_recruiting
NCT00911924
A Prospective, Unmasked Evaluation of the iStent in Patients With Primary Open-Angle GlaucomaNo drug interventionstreatment4completed
NCT01976624
Safety and Efficacy of Bimatoprost/Timolol (Ganfort®) Ophthalmic Solution in KoreaNot AvailableNot Availablecompleted
NCT05625958
Clinical Study Evaluating the Efficacy and Safety of CID v2.2 in Glaucoma SurgeryNo drug interventionstreatmentNot Availablenot_yet_recruiting
NCT01215786
Safety and Pharmacodynamics Study of AGN-207281 Ophthalmic Solutions Compared With Timolol Ophthalmic Solution or Placebo in Patients With Ocular Hypertension or Primary Open-Angle Glaucomatreatment1completed
NCT05236439
Study of a Cilioscleral Interposition Device (CID) SV22 in Patients With Primary Open Angle GlaucomaNo drug interventionstreatmentNot Availableactive_not_recruiting
NCT00991822
A Comparison of the Effect of Dorzolamide and Timolol on Optic Disk Blood Flow in Patients With Open Angle Glaucomabasic_science2 / 3completed
NCT00981422
Search for Biomarkers in Human Glaucoma: Lymphocytes Alterations and Rate of ProgressionNo drug interventionsNot AvailableNot Availablecompleted
NCT04297930
Treatment Outcomes of a Novel Glaucoma Tube Shunt Implant for Intraocular Pressure Control in Eyes With Refractory GlaucomaNo drug interventionsNot AvailableNot Availablecompleted
NCT04465630
A Prospective, Multicenter Study of the OMNI® Surgical System in Pseudophakic Eyes With Open Angle GlaucomaNo drug interventionstreatmentNot Availableterminated
NCT01282346
SOLX Gold Shunt for Refractory GlaucomaNo drug interventionstreatmentNot Availablecompleted
NCT03558126
Silicone Tube for the Surgical Treatment of GlaucomaNo drug interventionstreatmentNot Availablecompleted
NCT00570726
Treatment of Failing Blebs With Ranibizumabtreatment1completed
NCT04676126
Augmented Macular Pigment-containing Nutraceutical and Central Visual Functionprevention4withdrawn
NCT06355765
Citicoline & Antioxidants in GlaucomaNo drug interventionsNot AvailableNot Availablecompleted
NCT04460365
European Nutrition in Glaucoma Management TrialNo drug interventionstreatmentNot Availablecompleted
NCT00824720
Safety and Efficacy of a Glaucoma Drug Delivery SystemNo drug interventionstreatment2completed
NCT04651231
Punch Trabeculectomy Versus Classic TrabeculectomyNo drug interventionstreatmentNot Availablecompleted
NCT05043831
Direct Selective Laser Trabeculoplasty in Ethnic Chinese Population The Zhuiguang TrialNo drug interventionstreatmentNot Availablewithdrawn
NCT04920227
Comparation of CLASS Combined With Phacoemulsification and CLASS Alone in the Treatment of Primary Open Angle GlaucomaNo drug interventionstreatmentNot Availableunknown_status
NCT03966560
Choroidal Thickness and Its Correlations With Ocular Parameters in Primary Open-angle Glaucomatreatment4completed
NCT05159960
Optimal Treatment Protocol for Selective Laser Trabeculoplasty - Repeat TrialNo drug interventionstreatmentNot Availableenrolling_by_invitation
NCT00051194
A 6-week Safety & Efficacy Study of Combination Intraocular Pressure-lowering Therapy in Patients With Open-angle Glaucoma or Ocular HypertensionNo drug interventionstreatment2completed
NCT04912362
The Effectiveness of YAG Iridotomy in Preventing Peripheral Anterior Synechia After CLASS in Primary Open Angle GlaucomaNo drug interventionspreventionNot Availableunknown_status
NCT05451329
A Phase 2 Double-masked Study of VVN539 in Subjects With Elevated Intraocular PressureNo drug interventionstreatment2completed
NCT04632329
Negative Pressure Applied by the Equinox MPD for Severe Open Angle GlaucomaNo drug interventionsdevice_feasibilityNot Availablecompleted
NCT03800589
Assessment of Effectiveness Ex-Press Surgery ModificationNo drug interventionstreatmentNot Availablecompleted
NCT00311389
A 12-Month Study to Evaluate the Efficacy and Safety of Once-Daily Instillation of Combination Glaucoma Therapy in Patients With Open-Angle Glaucoma or Ocular Hypertensiontreatment3completed
NCT00934089
A Phase 2 Study Of The 24-Hour Intraocular Pressure Lowering And Systemic Exposure Of PF-04217329treatment2completed
NCT04702789
Comparative Study of the Efficacy of Either Krytantek Ofteno PF® or Eliptic Ofteno PF® Plus Gaap Ofteno PF® for POAG or Ocular Hypertension.treatment4terminated
NCT03949244
Nailfold Capillary Blood Flow With Latanoprost Bunodbasic_science4completed
NCT04406467
Retrospective Review of Xen Gel Stent Implantation With Open vs. Closed Conjunctiva ApproachNo drug interventionsNot AvailableNot Availablecompleted
NCT01243567
Safety and Efficacy of Bimatoprost/Timolol Fixed Combination Versus Latanoprost in Patients With Open-Angle Glaucoma Who Have Never Been Treatedtreatment4completed
NCT00150267
A 5-Year Postmarketing Safety Study Of Xalcom In Patients With Open Angle Glaucoma Or Ocular Hypertensiontreatment3completed
NCT01628601
GANfort® in Patients With Primary Open Angle Glaucoma or Ocular Hypertension Who Are Insufficiently Responsive to MonotherapyNot AvailableNot Availablecompleted
NCT02247804
Efficacy and Safety Study of Bimatoprost Sustained-Release (SR) in Participants With Open-angle Glaucoma or Ocular Hypertensiontreatment3completed
NCT04024072
To Compare the Safety and Efficacy of Perrigo's Product to an FDA Approved Product for the Treatment of Glaucoma or Ocular Hypertension in Both Eyestreatment3completed
NCT05405868
Nicotinamide in Glaucoma (NAMinG): A Randomised, Placebo-controlled, Multi-centre, Phase III Trialtreatment3recruiting
NCT03797469
Nutritional Supplements and Performance During Visual Field Testing (B3 Vitamin)No drug interventionsotherNot Availablecompleted
NCT05181046
Evaluation of Nanodropper-mediated Microdrops vs. Standard Drops of 0.5% Timolol Maleate in Glaucoma PatientsNo drug interventionstreatmentNot Availablecompleted
NCT02571712
Safety of GANFORT® Ophthalmic Solution in Chinese Patients With Open-angle Glaucoma or Ocular Hypertensiontreatment4completed
NCT06240312
Optic Nerve Head Strain as Biomarker for GlaucomaNo drug interventionsdiagnosticNot Availablerecruiting
NCT04658095
Study of OMNI Surgical System and iStent for Eyes With OAG (Trident)No drug interventionstreatmentNot Availableterminated
NCT01001195
Safety and Efficacy of Three Formulations of AGN-210669 Ophthalmic Solution Compared With Bimatoprost Ophthalmic Solutiontreatment2completed
NCT03736655
Study of a Novel Interposition Supraciliary Implant in Patients With Open Angle GlaucomaNo drug interventionstreatmentNot Availableterminated
NCT00051155
A 6-Week Safety and Efficacy Study of Travatan Compared to Xalcom in Subjects With Open-Angle Glaucoma(OAG) or Ocular Hypertension(OHT)treatment3completed
NCT06201455
Evaluation of Phacogoniotomy in Medically-controlled POAGNo drug interventionstreatmentNot Availablerecruiting
NCT01632423
A Study of Lumigan® in Patients With Primary Open Angle Glaucoma (POAG) or Ocular Hypertension (OHT)Not AvailableNot Availablecompleted
NCT04602923
Keratometric Change After XEN, Trabeculectomy and Tube ShuntsNo drug interventionstreatmentNot Availablecompleted
NCT01291108
Safety and Efficacy of AGN-210669 Ophthalmic Solution Compared With Bimatoprost Ophthalmic Solution in Patients With Open-Angle Glaucoma or Ocular Hypertensiontreatment2completed
NCT02379208
Evaluation of Rate of Progression With Perimetry in Newly Diagnosed Open Angle GlaucomaNo drug interventionsNot AvailableNot Availableunknown_status
NCT05498103
Use of Methazolamide to Lower Intraocular Pressuretreatment4active_not_recruiting
NCT04949802
Glaucoma Surgery Using the ViaLase Laser SystemNo drug interventionstreatmentNot Availablecompleted
NCT01253902
Ocular Surface Tolerability Study of Prostaglandin Analogues in Patients With Open-Angle Glaucoma or Ocular Hypertensiontreatment4completed
NCT03204487
A Study on the Effect of Changing From Preserved Prostaglandin Formulations to Preservative Free Tafluprost on Tear Film Thicknesstreatment4completed
NCT05130554
XEN45 in the Treatment of Chinese Patients With Primary Open-angle GlaucomaNo drug interventionstreatmentNot Availableunknown_status
NCT04619654
Visual Outcomes With a Trifocal IOL in Subjects With Open-angle GlaucomaNo drug interventionstreatmentNot Availablecompleted
NCT02250651
Efficacy and Safety of Bimatoprost Sustained-Release (SR) in Patients With Open-Angle Glaucoma or Ocular Hypertensiontreatment3completed
NCT05127551
Clinical Study of Glaukos® Trabecular Micro-Bypass System Model iS3 Infinite Vs. CompetitorNo drug interventionstreatmentNot Availableactive_not_recruiting
NCT03151577
Longitudinal Study on Glaucoma Surgery Using XEN® Gel StentNo drug interventionstreatmentNot Availableunknown_status
NCT05704777
Exercise Intervention in Primary Open-angle GlaucomaNo drug interventionstreatmentNot Availablenot_yet_recruiting
NCT04750447
Safety and Efficacy of an Ab Interno Gelatin Stent (XEN63) With or Without Mitomycin CNo drug interventionsNot AvailableNot Availableunknown_status
NCT05366647
GATT Versus Canaloplasty (GVC)No drug interventionstreatmentNot Availablenot_yet_recruiting
NCT06066645
Travoprost Intraocular Implant + iStent Infinite vs. iStent Infinite Alonetreatment3recruiting
NCT05624398
Results of Patients With Glaucoma Undergoing Minimally Invasive Glaucoma Surgery in Conjunction With Cataract SurgeryNo drug interventionstreatmentNot Availablerecruiting
NCT01547598
Safety and Efficacy of LUMIGAN® RC Versus DuoTrav® in Patients Who Require Further Intraocular Pressure (IOP) Reductiontreatment4completed
NCT03255798
A Prospective Evaluation of Glaucoma Subjects Treated With Two Second Generation iStents and One iStent SupraNo drug interventionstreatmentNot Availableterminated
NCT02863705
Efficacy and Safety of COMBIGAN® in Korean Patients With Primary Open Angle Glaucoma (POAG) and Normal Tension Glaucoma (NTG)treatment4completed
NCT03657797
Phase 2 Dose-Response Study Evaluating the Safety and Efficacy of NCX 470 vs Latanoprost in Subjects With Open-Angle Glaucoma or Ocular Hypertensiontreatment2completed
NCT02061683
A Study of Bimatoprost in the Treatment of Primary Open Angle Glaucoma and Ocular Hypertensiontreatment4completed
NCT03624361
MINIject Glaucoma Implant in European PatientsNo drug interventionstreatmentNot Availablecompleted
NCT05299593
24-hour Efficacy and Tolerability of the Tafluprost-timolol Fixed Association Without Preservatives in Glaucomatous or Ocular Hypertensive Patients Already Treated With Latanoprost Preserved With BAK. A Prospective, Open Study of 3 Months Duration.supportive_care4unknown_status
NCT05044793
A Clinical Study To Assess The Safety And Effectiveness Of The OMNI® Surgical SystemNo drug interventionsNot AvailableNot Availablecompleted
NCT03808688
Study of Rhopressa® for the Reduction of Elevated Intraocular Pressure in Patients With Glaucoma or Ocular Hypertension in a Real-world Settingtreatment4completed
NCT01629407
A Study of the Rate of Progression of Glaucoma During a Follow-up Period of Two YearsNo drug interventionsNot AvailableNot Availablecompleted
NCT01640756
AqueSys Microfistula Implant in Refractory GlaucomaNo drug interventionstreatment3completed
NCT01416415
Glaucoma Eye Drop Instillation: Impact of EducationNo drug interventionssupportive_careNot Availableterminated
NCT00801437
Non Interventional Study With Primary Open Angle Glaucoma and/or Ocular Hypertension Patients Treated With Xalacom® After Failure of Previous Antiglaucoma Therapy.Not AvailableNot Availablecompleted
NCT06582732
Performance of the Travoprost Intraocular Implanttreatment2completed
NCT00001152
Pigment Dispersion Syndrome With and Without GlaucomaNo drug interventionsNot AvailableNot Availablecompleted
NCT03996200
MINIject in Patients With Open Angle Glaucoma Using Single Operator Delivery ToolNo drug interventionstreatmentNot Availablecompleted
NCT01540370
Study Comparing Quantitative Assessments in Open-angle Glaucoma (OAG) and/or Ocular Hypertension (OHT)No drug interventionsNot AvailableNot Availablecompleted
NCT05277870
Use of Nanodropper vs. Standard Eyedropper in Patients With Glaucoma and Ocular HypertensionNo drug interventionssupportive_careNot Availablerecruiting
NCT01489670
Observational Study of Lumigan® 0.01% Treatment for Patients With Primary Open Angle Glaucoma or Ocular HypertensionNot AvailableNot Availablecompleted
NCT05949242
Clinical Outcomes in Cataract Surgery With OMNI Canaloplasty vs Cataract Surgery With OMNI Canaloplasty and Hydrus StentNo drug interventionstreatmentNot Availablerecruiting
NCT04900142
Micropulsed Laser Trabeculoplasty Using Different ParametersNo drug interventionstreatmentNot Availableunknown_status
NCT03624699
Investigation of the iStent Inject® Devices in Open-Angle GlaucomaNo drug interventionstreatmentNot Availablecompleted
NCT03445806
IOP Monitoring After Trabeculectomy Using iCare HomeNo drug interventionsNot AvailableNot Availableterminated
NCT02114073
Comparison of Effect of Postoperative Cyclosporine A 2% Ophthalmic Emulsion and Betamethasone Eye Drop on Surgical Success of Trabeculectomy Proceduretreatment2completed
NCT02036541
AqueSys XEN 45 Glaucoma Implant in Refractory GlaucomaNo drug interventionstreatmentNot Availablecompleted
NCT00382395
SOLX Gold Shunt Versus Control Implant: Randomized Trial for Refractory GlaucomaNo drug interventionstreatment3suspended
NCT00347191
Relationship Between Central Corneal Thickness and Intraocular Pressure Measures Instruments.No drug interventionsNot AvailableNot Availablecompleted
NCT00219596
Xalacom And Combination Of Unfixed Latanoprost And Timolol In Subjects With Open-Angle Glaucoma Or Ocular Hypertensiontreatment3completed
NCT00145535
SOLX Titanium Sapphire Laser for TrabeculoplastyNo drug interventionstreatment3completed
NCT03634319
Early Evaluation of the Beacon Aqueous Microshunt in Patients Refractory to Drug Therapy in the European UnionNo drug interventionstreatmentNot Availableterminated
NCT03612817
Preservative-free Tafluprost/Timolol Fixed Combination: Morning vs Evening Dosingtreatment4completed
NCT03868124
Clinical Study Comparing Two Models of a Travoprost Intraocular Implanttreatment3active_not_recruiting
NCT05325996
Evaluating Home Testing Devices for the Management of GlaucomaNo drug interventionsdiagnosticNot Availablerecruiting
NCT01254058
Saccadic Eye Movements Are Impaired In GlaucomaNo drug interventionsNot AvailableNot Availableunknown_status
NCT03519386
Randomized Study Comparing Two Models of a Travoprost Intraocular Implant to Timolol Maleate Ophthalmic Solution, 0.5%treatment3active_not_recruiting
NCT03369886
The Relationship Between Macular OCTA and GCIPL and Their Combinational Index Using AINo drug interventionsdiagnosticNot Availableunknown_status
NCT05885022
Feasibility Clinical Evaluation of the Calibreye SystemNo drug interventionstreatmentNot Availablerecruiting
NCT06154330
Safety and Efficacy of Suprachoroidal Tube Shunt in Patients With Primary Open and Pseudoexfoliation GlaucomasNo drug interventionsNot AvailableNot Availablerecruiting
NCT03870230
Investigation of Neurovascular Coupling in Glaucoma Patients and Healthy SubjectsNo drug interventionsbasic_scienceNot Availableunknown_status
NCT04872348
An Observational Multicenter Clinical Study To Assess The Safety And Effectiveness Of The OMNI® Surgical System In Pseudophakic Eyes With Primary Open Angle Glaucoma (ORION 2.0)No drug interventionsNot AvailableNot Availablecompleted
NCT05401357
Bioequivalence Study With Clinical Endpoint Comparing Bimatoprost Ophthalmic Solution 0.01% and LUMIGAN® in the Treatment of Chronic Open-Angle Glaucoma or Ocular Hypertension in Both Eyes.treatment3unknown_status
NCT05626426
Electrical Stimulation for the Treatment of Optic NeuropathiesNo drug interventionstreatmentNot Availablerecruiting
NCT00707226
Circadian Variations in Ocular Blood Flow in Glaucomatous and Normal EyesNo drug interventionsNot AvailableNot Availablecompleted
NCT04903366
Absorption and Safety of Topical Timolol to Treat Chronic WoundsNot AvailableNot Availablecompleted
NCT02679482
Following Patients After Selective and Pascal Laser Trabeculoplasty for Treatment of Chronic Open-Angle GlaucomaNo drug interventionsNot AvailableNot Availableunknown_status
NCT04616573
A Post-market Study Of Use Of The OMNI® Surgical System In Open Angle GlaucomaNo drug interventionstreatmentNot Availableterminated
NCT04007276
The Effect of Lumify™ on Ocular Redness, Intraocular Pressure, and Eyelid Position in Glaucoma Patientstreatment4not_yet_recruiting
NCT02388360
The Impact of Topical Prostaglandins on the Biomechanical Properties of the Cornea in Patients With Open Angle GlaucomaNo drug interventionstreatment4completed
NCT05626491
Electrical Stimulation for the Treatment of GlaucomaNo drug interventionstreatmentNot Availablerecruiting
NCT06289491
Randomized Trial of Hydrus Microstent Versus GoniotomyNo drug interventionstreatmentNot Availablenot_yet_recruiting
NCT03267862
Scleral Response to Intraocular Pressure (IOP)No drug interventionsNot AvailableNot Availablecompleted
NCT04202562
Efficacy and Safety of ab Interno Trabeculectomy With the Kahook Dual BladeNo drug interventionstreatmentNot Availablecompleted
NCT00140062
Efficacy And Safety Of Xalatan Compared To Usual Care In Patients With Open Angle Glaucoma Or Ocular Hypertension.treatment4completed
NCT02338362
Inhaled Corticosteroids: Effect on Intraocular Pressure in Patients With Controlled Glaucomaother4completed
NCT00913029
Evaluation of the iStent Versus Two Ocular Hypotensive Agents in Patients With Primary Open-angle Glaucoma (POAG)treatment4completed
NCT00143429
Corneal Versus Conjunctival Delivery Using a Delivery Devicetreatment2withdrawn
NCT03293992
A Study of the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of RO7058584 Following 7 Days of Instillation of Eye Drops in Patients With Primary Open Angle Glaucoma or Ocular Hypertensiontreatment1completed
NCT01857440
The Flashing Light-Induced Pupil Response (FLIPR) Glaucoma StudyNo drug interventionsNot AvailableNot Availablecompleted
NCT01241240
Safety and Efficacy of Triple Combination Therapy in Patients With Primary Open-Angle Glaucoma or Ocular Hypertensiontreatment3completed
NCT00410267
Trial Comparing Ketorolac Tromethamine 0.4% & Prednisolone Acetate 1% in Reducing Post-SLT Anterior Chamber Flare & CellsNo drug interventionsNot AvailableNot Availableterminated
NCT05857267
Dorzolamide+Timolol Multidose Preservative-free vs Dorzolamida+Timolol BAK Preserved Efficacy and Safetytreatment4recruiting
NCT00647101
A Study to Assess the Efficacy of 3 Months of Latanoprost Treatment in Reducing the Intraocular Pressure in Patients With Ocular Hypertension or Open-angle Glaucomatreatment4completed
NCT00753168
Phase 1-2 Evaluation of OT-730 Eye Drops in Reducing the Intraocular Pressure in Patients With Ocular Hypertension or Open-Angle Glaucomatreatment1 / 2completed
NCT00051168
A Long-term Safety Study of Once-daily Travatantreatment3completed
NCT01637246
A Study of Patients With Primary Open Angle Glaucoma or Ocular Hypertension Who Were Insufficiently Responsive to MonotherapyNo drug interventionsNot AvailableNot Availablecompleted
NCT02020512
A Study of 0.03% Bimatoprost in the Treatment of Primary Open Angle Glaucoma and Ocular Hypertensiontreatment4completed
NCT04476810
Long Term Outcome of Combined Phacoemulsification and Excisional Goniotomy With the Kahook Dual BladeNo drug interventionstreatmentNot Availablecompleted
NCT01589510
A Study of Lumigan® 0.01% in Patients With Primary Open Angle Glaucoma (POAG) or Ocular Hypertension (OHT)Not AvailableNot Availablecompleted
NCT03106181
A Comparison of Cataract Surgery Alone and Cataract Surgery With iStentNo drug interventionstreatmentNot Availablecompleted
NCT01628614
A Study of Intraocular Pressure (IOP) Reduction in Newly Diagnosed Patients With Primary Open Angle Glaucoma (POAG) or Ocular Hypertension (OHT)No drug interventionsNot AvailableNot Availablecompleted
NCT01735214
An Observational Study of Patients With Primary Open Angle Glaucoma (POAG) or Ocular Hypertension (OHT) Who Switched IOP-lowering TreatmentsNo drug interventionsNot AvailableNot Availablecompleted
NCT02376114
Ginkgo Biloba and Ocular Blood Flow in Primary Open-angle Glaucomatreatment2completed
NCT00487214
Internet-based, Naturalistic Evaluation of Tolerability and Individual Patient Target Pressures With Bimatoprost 0.03% in GlaucomaNo drug interventionsNot AvailableNot Availablecompleted
NCT00334750
Distribution of Risk Factors in Ocular Hypertension and Open-Angle Glaucoma Patients in CanadaNo drug interventionsNot AvailableNot Availablecompleted
NCT01430923
Clinical Evaluation of Safety and Efficacy of Refrigeration Free LatanoprosttreatmentNot Availableunknown_status
NCT03798223
Optimal Treatment Protocol for Selective Laser TrabeculoplastyNo drug interventionstreatmentNot Availableactive_not_recruiting
NCT03274323
Trabeculectomy Versus 2-iStent and Prostaglandin StudyNo drug interventionstreatmentNot Availablewithdrawn
NCT00486252
Non Interventional Study in Patients With Open Angle Glaucoma and/or Ocular Hypertension Treated With XALATAN®No drug interventionsNot AvailableNot Availablecompleted
NCT04064918
Effects of Netarsudil and Timolol on Retinal Blood Vessel Density and Visual AcuityNo drug interventionsotherNot Availablewithdrawn
NCT05271734
Evaluation of the Compatibility of Different Eye Lid Retractors to the Direct Selective Laser Trabeculoplasty (DSLT) ProcedureNo drug interventionstreatmentNot Availablecompleted
NCT03931317
Study Comparing the Effects of Latanoprostene Bunod and Timolol on Retinal Blood Vessel Density and Visual AcuityotherNot Availablecompleted
NCT05932940
Incidence of Descemet Membrane Detachment Post GATT by AS OCTNo drug interventionsdiagnosticNot Availableactive_not_recruiting