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Displaying drugs 676 - 700 of 13886 in total

Didanosine

A dideoxynucleoside compound in which the 3'-hydroxy group on the sugar moiety has been replaced by a hydrogen. This modification prevents the formation of phosphodiester linkages which are needed for the completion of nucleic acid chains. Didanosine is a potent inhibitor of HIV replication, acting as a chain-terminator of viral...
Approved
Matched Description: … A dideoxynucleoside compound in which the 3'-hydroxy group on the sugar moiety has been replaced ... This modification prevents the formation of phosphodiester linkages which are needed for the completion ... by a hydrogen. …
Matched Categories: … Antivirals for Systemic Use ... Antiinfectives for Systemic Use …

Palivizumab

Humanized monoclonal antibody (IgG1k) produced by recombinant DNA technology, directed to an epitope in the A antigenic site of the F protein of respiratory syncytial virus (RSV). Synagis is a composite of human (95%) and murine (5%) antibody sequences. The human heavy chain sequence was derived from the constant domains...
Approved
Investigational
Matched Description: … Humanized monoclonal antibody (IgG1k) produced by recombinant DNA technology, directed to an epitope in ... Synagis is a composite of human (95%) and murine (5%) antibody sequences. ... the A antigenic site of the F protein of respiratory syncytial virus (RSV). …
Matched Categories: … Antiinfectives for Systemic Use …
Matched Products: … Synagis 100mg/ml solution for Injection ... SYNAGIS SOLUTION FOR INJECTION 100MG/ML ... SYNAGIS STERILE POWDER FOR INJECTION 100 mg/vial …

Technetium Tc-99m nofetumomab merpentan

Technetium Tc-99m nofetumomab merpentan (Tc-99m nm) consists of a Fab fragment of an IgG2b of the pancarcinoma murine antibody NR-LU-10. The NR-LU-10 antibody is directed against a 40 kDa glycoprotein antigen expressed in a variety of cancers and some normal tissues.[FDA label] Tc-99m nm was developed by Boehringer Ingelheim Pharma...
Approved
Withdrawn
Matched Description: … [A32115] The NR-LU-10 antibody is directed against a 40 kDa glycoprotein antigen expressed in a variety ... It was after discontinued on August 13, 2013, but in the 2018 FDA submission list, it can be found as ... a substance type II (Drug substance) with an active status. …

Difluprednate

Difluprednate is a topical corticosteroid indicated for the treatment of infammation and pain associated with ocular surgery. It is a butyrate ester of 6(α), 9(α)-difluoro prednisolone acetate. Difluprednate is abbreviated DFBA, or difluoroprednisolone butyrate acetate. It is indicated for treatment of endogenous anterior uveiti.
Approved
Matched Iupac: … 5,9b-difluoro-10-hydroxy-9a,11a-dimethyl-7-oxo-1H,2H,3H,3aH,3bH,4H,5H,7H,9aH,9bH,10H,11H,11aH-cyclopenta[a] …
Matched Description: … Difluprednate is a topical corticosteroid indicated for the treatment of infammation and pain associated ... It is indicated for treatment of endogenous anterior uveiti. ... It is a butyrate ester of 6(α), 9(α)-difluoro prednisolone acetate. …

Altretamine

An alkylating agent proposed as an antineoplastic. It also acts as a chemosterilant for male houseflies and other insects.
Approved
Matched Description: … It also acts as a chemosterilant for male houseflies and other insects. …

Regadenoson

Regadenoson is an A2A adenosine receptor agonist that causes coronary vasodilation and used for myocardial perfusion imagining. Manufactured by Astellas and FDA approved April 10, 2008.
Approved
Investigational
Matched Description: … Regadenoson is an A2A adenosine receptor agonist that causes coronary vasodilation and used for myocardial …
Matched Categories: … Adenosine A receptor agonists …

Gluconic Acid

Commonly found in salts with sodium and calcium. Gluconic acid or gluconate is used to maintain the cation-anion balance on electrolyte solutions.
Approved
Investigational
Matched Description: … Commonly found in salts with sodium and calcium. …
Matched Mixtures name: … Plasma-Lyte A ... Isolyte S in Dextrose ... PLASMA-LYTE A INJECTION …

Hexachlorophene

A chlorinated bisphenol antiseptic with a bacteriostatic action against Gram-positive organisms, but much less effective against Gram-negative organisms. It is mainly used in soaps and creams and is an ingredient of various preparations used for skin disorders. (From Martindale, The Extra Pharmacopoeia, 30th ed, p797)
Approved
Withdrawn
Matched Description: … It is mainly used in soaps and creams and is an ingredient of various preparations used for skin disorders ... A chlorinated bisphenol antiseptic with a bacteriostatic action against Gram-positive organisms, but …

Avapritinib

Avapritinib, or BLU-285, is a selective tyrosine kinase inhibitor of KIT and platelet derived growth factor receptor alpha indicated for the treatment of unresectable, metastatic gastrointestinal stromal tumors and advanced systemic mastocytosis.[A189339,L40363] It is one of the first medications available for the treatment of multidrug resistant cancers. Avapritinib shares a...
Approved
Investigational
Matched Description: … [A189327] Avapritinib shares a similar mechanism with [ripretinib]. ... Avapritinib, or BLU-285,[A189327] is a selective tyrosine kinase inhibitor of KIT and platelet derived ... growth factor receptor alpha indicated for the treatment of unresectable, metastatic gastrointestinal …

Haloprogin

Haloprogin is used as a topical ointment or cream in the treatment of Tinea infections. Tinea infections are superficial fungal infections caused by three species of fungi collectively known as dermatophytes (Trichophyton, Microsporum and Epidermophyton). Commonly these infections are named for the body part affected, including tinea corporis (general skin),...
Approved
Withdrawn
Matched Description: … Haloprogin is used as a topical ointment or cream in the treatment of Tinea infections. ... Haloprogin is a halogenated phenolic ether administered topically for dermotaphytic infections. ... Haloprogin is no longer available in the United States and has been discontinued. …
Matched Categories: … Antifungals for Topical Use ... Antifungals for Dermatological Use …

Dexbrompheniramine

Dexbrompheniramine maleate is an antihistamine agent that is used for the treatment of allergic conditions, such as hay fever or urticaria.
Approved
Matched Description: … Dexbrompheniramine maleate is an antihistamine agent that is used for the treatment of allergic conditions …
Matched Mixtures name: … Supress A …
Matched Categories: … Antihistamines for Systemic Use …

Pivmecillinam

Pivmecillinam is a mecillinam prodrug, a pivaloyloxymethyl ester of amdinocillin that is well absorbed orally, but broken down to amdinocillin in the intestinal mucosa. It is active against gram-negative organisms and used as for amdinocillin. [PubChem]
Approved
Matched Description: … orally, but broken down to amdinocillin in the intestinal mucosa. ... It is active against gram-negative organisms and used as for amdinocillin. [PubChem] ... Pivmecillinam is a mecillinam prodrug, a pivaloyloxymethyl ester of amdinocillin that is well absorbed …
Matched Categories: … Antibacterials for Systemic Use ... Antiinfectives for Systemic Use …

Bictegravir

Bictegravir is a recently approved investigational drug that has been used in trials studying the treatment of HIV-1 and HIV-2 infection. It has been approved for HIV-1 monotherapy combined with 2 other antiretrovirals in a single tablet.
Approved
Investigational
Matched Description: … It has been approved for HIV-1 monotherapy combined with 2 other antiretrovirals in a single tablet. ... Bictegravir is a recently approved investigational drug that has been used in trials studying the treatment …
Matched Categories: … Antivirals used in combination for the treatment of HIV infections ... Antivirals for Systemic Use ... Antiinfectives for Systemic Use …

Fluorometholone

A glucocorticoid employed, usually as eye drops, in the treatment of allergic and inflammatory conditions of the eye. It has also been used topically in the treatment of various skin disorders. (From Martindale, The Extra Pharmacopoeia, 30th ed, p732)
Approved
Investigational
Matched Iupac: … 9b-fluoro-1,10-dihydroxy-5,9a,11a-trimethyl-1H,2H,3H,3aH,3bH,4H,5H,7H,9aH,9bH,10H,11H,11aH-cyclopenta[a] …
Matched Description: … A glucocorticoid employed, usually as eye drops, in the treatment of allergic and inflammatory conditions ... It has also been used topically in the treatment of various skin disorders. …
Matched Categories: … Agents for Treatment of Hemorrhoids and Anal Fissures for Topical Use ... Anti-Acne Preparations for Topical Use …

Masoprocol

A potent lipoxygenase inhibitor that interferes with arachidonic acid metabolism. The compound also inhibits formyltetrahydrofolate synthetase, carboxylesterase, and cyclooxygenase to a lesser extent. It also serves as an antioxidant in fats and oils. [PubChem]
Approved
Investigational
Matched Description: … It also serves as an antioxidant in fats and oils. [PubChem] ... A potent lipoxygenase inhibitor that interferes with arachidonic acid metabolism. ... The compound also inhibits formyltetrahydrofolate synthetase, carboxylesterase, and cyclooxygenase to a …
Matched Categories: … Compounds used in a research, industrial, or household setting …

Ziprasidone

Disorders such as schizophrenia and bipolar disorder can significantly impair mood, cognition, and behavior. These mental illnesses can often be accompanied by comorbidities such as depression and substance abuse, and can significantly impact the quality of life of patients and caregivers. Luckily, several treatment options for psychotic disorders have been...
Approved
Matched Description: … [A190525] Luckily, several treatment options for psychotic disorders have been introduced to market since ... [A180748] Although ziprasidone is classified as an atypical antipsychotic, it appears to have a lower ... the realization of chlorpromazine's antipsychotic properties in 1952. …

Terbinafine

Terbinafine hydrochloride (Lamisil) is a synthetic allylamine antifungal.[L9065,L9068] It is highly lipophilic in nature and tends to accumulate in skin, nails, and fatty tissues. Like other allylamines, terbinafine inhibits ergosterol synthesis by inhibiting the fungal squalene monooxygenase (also called squalene epoxidase), an enzyme that is part of the fungal cell...
Approved
Investigational
Vet approved
Matched Description: … Terbinafine hydrochloride (Lamisil) is a synthetic allylamine antifungal. ... [L9065,L9068] It is highly lipophilic in nature and tends to accumulate in skin, nails, and fatty tissues …
Matched Categories: … Antifungals for Topical Use ... Antifungals for Systemic Use ... Antifungals for Dermatological Use …
Matched Products: … Lamisil AT for Jock Itch …

Benzylpenicilloyl polylysine

Benzylpenicilloyl polylysine is used as a skin-testing reagent to detect immunoglobulin E antibodies in people with a history of penicillin allergy. The quantitation of in vitro IgE antibodies to the benzylpenicilloyl determinant is a useful tool for evaluating allergic subjects.
Approved
Matched Description: … The quantitation of in vitro IgE antibodies to the benzylpenicilloyl determinant is a useful tool for ... in people with a history of penicillin allergy. ... Benzylpenicilloyl polylysine is used as a skin-testing reagent to detect immunoglobulin E antibodies …
Matched Categories: … Antibacterials for Systemic Use ... Antiinfectives for Systemic Use …

Carprofen

Carprofen is a non-steroidal anti-inflammatory drug (NSAID) that is used by veterinarians as a supportive treatment for the relief of arthritic symptoms in geriatric dogs. Carprofen was previously used in human medicine for over 10 years (1985-1995). It was generally well tolerated, with the majority of adverse effects being mild,...
Approved
Vet approved
Withdrawn
Matched Description: … treatment for the relief of arthritic symptoms in geriatric dogs. ... Carprofen was previously used in human medicine for over 10 years (1985-1995). ... Carprofen is a non-steroidal anti-inflammatory drug (NSAID) that is used by veterinarians as a supportive …

Carbenicillin

Broad-spectrum semisynthetic penicillin derivative used parenterally. It is susceptible to gastric juice and penicillinase and may damage platelet function.
Approved
Investigational
Matched Categories: … Antibacterials for Systemic Use ... Antiinfectives for Systemic Use …

Potassium bicarbonate

Potassium bicarbonate is a white, crystalline, slightly alkaline and salty substance. It is produced by the passage of carbon dioxide through an aqueous potassium carbonate solution. It is used in medicine as an antacid. It is registered in the FDA under the section of suitable, safe and effective ingredients for...
Approved
Matched Description: … [T141] It is registered in the FDA under the section of suitable, safe and effective ingredients for ... It is used in medicine as an antacid. ... Potassium bicarbonate is a white, crystalline, slightly alkaline and salty substance. …

Flutemetamol (18F)

Flutemetamol (18F) is a PET scanning radiopharmaceutical containing the radionuclide fluorine-18. It is indicated for Positron Emission Tomography (PET) imaging of the brain to estimate β amyloid neuritic plaque density in adult patients with cognitive impairment who are being evaluated for Alzheimer's disease (AD) or other causes of cognitive decline.
Approved
Investigational
Matched Description: … plaque density in adult patients with cognitive impairment who are being evaluated for Alzheimer's disease ... Flutemetamol (18F) is a PET scanning radiopharmaceutical containing the radionuclide fluorine-18. ... It is indicated for Positron Emission Tomography (PET) imaging of the brain to estimate β amyloid neuritic …
Matched Categories: … Compounds used in a research, industrial, or household setting …

Chromium picolinate

Chromium picolinate has a chemical formula CrPic3 and reddish-pink color. It is a coordination complex consisting of chromium(III) and picolinic acid. Chromium picolinate is used as a nutritional supplement for optimal insulin function in patients with Type 2 diabetes or promotion of weight loss. Chromium ions are shown to regulate...
Approved
Matched Description: … Chromium picolinate is used as a nutritional supplement for optimal insulin function in patients with ... Chromium picolinate has a chemical formula CrPic3 and reddish-pink color. ... It is a coordination complex consisting of chromium(III) and picolinic acid. …
Matched Mixtures name: … BLACKMORES teen multi for GUYS capsule …
Matched Categories: … Compounds used in a research, industrial, or household setting …

Liotrix

Liotrix is a synthetically derived thyroid hormone replacement preparation. It consists of levothyroxine sodium (thyroxine, T4) and liothyronine sodium (triiodothyronine, T3) in a 4 to 1 ratio by weight. Liotrix was developed when it was believed that serum levels of both T4 and T3 were maintained by direct thyroidal secretion....
Approved
Matched Description: … Administration of levothyroxine alone is sufficient for maintaining serum T4 and T3 levels in most patients ... In fact, administration of T3 may result in supratherapeutic levels of T3. ... a 4 to 1 ratio by weight. …

SARS-CoV-2 virus recombinant spike (S) protein receptor binding domain (RBD) fusion heterodimer (B.1.351-B.1.1.7 strains)

Bimervax is an adjuvanted non-mRNA COVID-19 vaccine utilizing a SARS-CoV-2 recombinant spike (S) protein receptor binding domain (RBD) fusion heterodimer. It is intended to elicit protection against Omicron XBB.1.5, one of the dominant circulating SARS-CoV-2 subvariants in 2023. It is produced using recombinant DNA technology in CHO cell lines and...
Approved
Matched Description: … [L48902,L48907] Bimervax was issued marketing authorization in the EU in March 2023 for use as a booster ... Human Health S.L. for the European market. ... Bimervax is an adjuvanted non-mRNA COVID-19 vaccine utilizing a SARS-CoV-2 recombinant spike (S) protein …
Displaying drugs 676 - 700 of 13886 in total