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Sodium phosphate, dibasic

Approved
Matched Synonyms: … Phosphoric acid, sodium salt (1:2) ... Disodium acid phosphate ... Phosphoric acid, disodium salt, anhydrous …
Matched Salts cas: … 10028-24-7 ... 7782-85-6 ... 10039-32-4 ... 118830-14-1 …
Matched Mixtures name: … Phoxillum B22k4/0 ... Aminosyn II 7% M In 10% Dextrose(dual Chamber) ... Heparin Sodium In 5% Dextrose Injection, 25000unit/500ml …

Flecainide

Flecainide is a Class I anti-arrhythmic agent like encainide and propafenone. Flecainide’s development began in 1966 and was first synthesized in 1972 as an attempt to generate new anesthetics. It is used to prevent supraventricular and ventricular arrhythmias, as well as paroxysmal atrial fibrillation and flutter.[L8878,L5056] Flecainide was granted FDA...
Approved
Withdrawn
Matched Synonyms: … N-(2-Piperidinylmethyl)-2,5-bis(2,2,2-trifluoroethoxy)benzamide …
Matched Iupac: … N-[(piperidin-2-yl)methyl]-2,5-bis(2,2,2-trifluoroethoxy)benzamide …
Matched Salts cas: … 54143-56-5 …
Matched Categories: … MATE 1 Inhibitors ... MATE 1 Substrates ... Heterocyclic Compounds, 1-Ring ... MATE 1 Substrates with a Narrow Therapeutic Index ... P-glycoprotein substrates …

Lysine

Lysine (abbreviated as Lys or K) is an α-amino acid with the chemical formula HO2CCH(NH2)(CH2)4NH2. This amino acid is an essential amino acid, which means that humans cannot synthesize it. Its codons are AAA and AAG. Lysine is a base, as are arginine and histidine. The ε-amino group acts as...
Approved
Nutraceutical
Matched Synonyms: … (S)-2,6-diaminohexanoic acid ... (S)-α,ε-diaminocaproic acid ... 6-ammonio-L-norleucine …
Matched Iupac: … (2S)-2,6-diaminohexanoic acid …
Matched Description: … This amino acid is an essential amino acid, which means that humans cannot synthesize it. ... Common posttranslational modifications include methylation of the ε-amino group, giving methyl-, dimethyl ... Lysine (abbreviated as Lys or K) is an α-amino acid with the chemical formula HO2CCH(NH2)(CH2)4NH2. …
Matched Salts cas: … 657-27-2 ... 57282-49-2 …
Matched Mixtures name: … Amino Acid InJ.W.O.elect.5%dext. ... 4.25%travasol Amino Acid InJ.W.elecw.5%dex. ... 2.75%travasol Amino Acid InJ.W.eleC.W.5%dex. …
Matched Categories: … Amino Acids ... Amino Acids, Basic ... Amino Acids, Diamino ... Amino Acids, Essential ... Proteinogenic Amino Acids …

Calcium carbonate

Calcium carbonate is an inorganic salt used as an antacid. It is a basic compound that acts by neutralizing hydrochloric acid in gastric secretions. Subsequent increases in pH may inhibit the action of pepsin. An increase in bicarbonate ions and prostaglandins may also confer cytoprotective effects. Calcium carbonate may also...
Approved
Investigational
Matched Synonyms: … Carbonic acid calcium salt (1:1) ... Calcium carbonate (1:1) …
Matched Description: … It is a basic compound that acts by neutralizing hydrochloric acid in gastric secretions. …
Matched Mixtures name: … P-NATAL® ... Irospan 24/6 ... NEUTROSE S. PELLEGRINO …
Matched Categories: … Carbonic Acid ... Gastric Acid Lowering Agents ... Drugs for Acid Related Disorders ... ascorbic acid (vit C) and calcium …
Matched Products: … Co De R T ... ACID STOP ... 7 Select Antacid …

Benzoin

Benzoin is a white crystalline compound prepared by condensation of benzaldehyde in potassium cyanide, and is used in organic syntheses. This should not be confused with benzoin gum from STYRAX (see DB11222). Benzoin is an FDA-approved colour additive used for marking fruits and vegetables.
Approved
Experimental
Matched Synonyms: … 2-Hydroxy-1,2-diphenylethanone ... Hydroxy-2-phenyl acetophenone …
Matched Iupac: … 2-hydroxy-1,2-diphenylethan-1-one …
Matched Description: … Benzoin is a white crystalline compound prepared by condensation of benzaldehyde in potassium cyanide …

Gabapentin

Gabapentin is a structural analogue of the inhibitory neurotransmitter gamma-aminobutyric acid (GABA) that was first approved for use in the United States in 1993. It was originally developed as a novel anti-epileptic for the treatment of certain types of seizures[A186277,A186143] - today it is also widely used to treat neuropathic...
Approved
Investigational
Matched Synonyms: … 1-(Aminomethyl)cyclohexaneacetic acid …
Matched Iupac: … 2-[1-(aminomethyl)cyclohexyl]acetic acid …
Matched Description: … Gabapentin is a structural analogue of the inhibitory neurotransmitter gamma-aminobutyric acid ([GABA …
Matched Mixtures name: … Innoprax-5 …
Matched Categories: … Carboxylic Acids ... Amino Acids ... Amino Acids, Peptides, and Proteins …
Matched Products: … GABAPENTIN HEXAL A/S ... NERUDA 250 MG/5 ML ORAL COZELTI, 470 ML ... GEMUDA 250MG/5ML ORAL ÇÖZELTI, 470 ML, 1 ŞIŞE …

Magnesium sulfate

A small colorless crystal used as an anticonvulsant, a cathartic, and an electrolyte replenisher in the treatment of pre-eclampsia and eclampsia. It causes direct inhibition of action potentials in myometrial muscle cells. Excitation and contraction are uncoupled, which decreases the frequency and force of contractions. (From AMA Drug Evaluations Annual,...
Approved
Investigational
Vet approved
Matched Synonyms: … Magnesium sulfate (1:1) …
Matched Iupac: … magnesium(2+) sulfate …
Matched Salts cas: … 17830-05-6 ... 14168-73-1 …
Matched Mixtures name: … Magnesium Sulfate In 5% Dextrose Inj(20mg/ml) ... Sodium Sulfate, Potassium Sulfate, Magnesium Sulfate ... Sodium Sulfate, Potassium Sulfate, Magnesium Sulfate …
Matched Products: … Pepsom Flying P Epsom Salt ... SULFATO DE MAGNESIO 2 G/10 ML ... MG 5 SULFAT 10% …

Sodium bicarbonate

Sodium bicarbonate is a white, crystalline powder that is commonly used as a pH buffering agent, an electrolyte replenisher, systemic alkalizer and in topical cleansing solutions.
Approved
Matched Synonyms: … Sodium acid carbonate ... Carbonic acid monosodium salt …
Matched Mixtures name: … Prismasol 2 mmol/l Potassium ... multiBic® 3 mmol/l potassium Solution for Haemofiltration ... MILPAX S SUSPENSION …
Matched Categories: … Carbonic Acid ... Gastric Acid Lowering Agents …
Matched Products: … BIBAG(R) ... SODIUM BICARBONATE 4% (2.4%mEq) ... BICARBONATO DE SODIO 1 MOLAR …

Raltegravir

Raltegravir is an antiretroviral drug produced by Merck & Co., used to treat HIV infection. It received approval by the U.S. Food and Drug Administration (FDA) on 12 October 2007, the first of a new class of HIV drugs, the integrase inhibitors, to receive such approval.
Approved
Matched Iupac: … N-[(4-fluorophenyl)methyl]-5-hydroxy-1-methyl-2-{2-[(5-methyl-1,3,4-oxadiazol-2-yl)formamido]propan-2 ... -yl}-6-oxo-1,6-dihydropyrimidine-4-carboxamide …
Matched Salts cas: … 871038-72-1 …
Matched Salts name: … Raltegravir potassium …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Products: … Raltegravir Potassium …

Albuterol

Salbutamol (Albuterol [USAN]) is a short-acting, selective beta2-adrenergic receptor agonist used in the treatment of asthma and COPD. It is 29 times more selective for beta2 receptors than beta1 receptors giving it higher specificity for pulmonary beta receptors versus beta1-adrenergic receptors located in the heart. Salbutamol is formulated as a...
Approved
Vet approved
Matched Iupac: … 4-[2-(tert-butylamino)-1-hydroxyethyl]-2-(hydroxymethyl)phenol …
Matched Description: … The R-isomer has 150 times greater affinity for the beta2-receptor than the S-isomer and the S-isomer ... Salbutamol is formulated as a racemic mixture of the R- and S-isomers. ... This lead to the development of levalbuterol, the single R-isomer of salbutamol. …
Matched Mixtures name: … PRALAS 100 MCG/20 MCG İNHALASYON İÇİN ÇÖZELTİ İÇEREN ÖLÇÜLÜ DOZLU AEROSOL, 1 ADET ... Ibicar S (Salbutamol 100 mcg/actuation and Beclometasone 50 mcg/actuation) Pressurised Inhalation …
Matched Categories: … Amino Alcohols ... Adrenergic beta-2 Receptor Agonists ... Selective Beta 2-adrenergic Agonists ... Cytochrome P-450 CYP3A Inhibitors ... Cytochrome P-450 CYP3A4 Inhibitors …
Matched Products: … METRAST 2 MG/5 ML ŞURUP ,150 ML, 1 ŞIŞE ... SALBUTAMOL 2 MG/ 1 ML AEROSOL (SALBUTAMOL 100 MCG) ... ASMOL SYRUP 2 mg/5 ml …

Isoflurane

A stable, non-explosive inhalation anesthetic, relatively free from significant side effects.
Approved
Vet approved
Matched Synonyms: … 1-chloro-2,2,2-trifluoroethyl difluoromethyl ether …
Matched Iupac: … 2-chloro-2-(difluoromethoxy)-1,1,1-trifluoroethane …
Matched Categories: … Cytochrome P-450 Substrates ... Cytochrome P-450 CYP2B6 Inducers ... Cytochrome P-450 Enzyme Inducers ... Cytochrome P-450 CYP2B6 Substrates ... Cytochrome P-450 CYP2E1 Substrates …

Spironolactone

Spironolactone is a potassium-sparing diuretic. It binds to mineralocorticoid receptors and functions as aldosterone antagonists. It promotes sodium and water excretion and potassium retention. Spironolactone was originally developed purely for this ability before other pharmacodynamic properties of the drug were discovered.[A11837, A178246] It is indicated to treat several conditions, including...
Approved
Matched Iupac: … [cyclopenta[a]phenanthrene-1,2'-oxolane]-5',7-dione ... (1R,3aS,3bR,4R,9aR,9bS,11aS)-4-(acetylsulfanyl)-9a,11a-dimethyl-2,3,3a,3b,4,5,7,8,9,9a,9b,10,11,11a-tetradecahydrospiro …
Matched Description: … Spironolactone is a potassium-sparing diuretic. ... [A178192] It promotes sodium and water excretion and potassium retention. …
Matched Mixtures name: … Dapsone 6% / Niacinamide 2% / Spironolactone 5% ... Clindamycin 1% / Niacinamide 4% / Spironolactone 2% / Tretinoin 0.025% ... 011503 Dapsone 6% / Niacinamide 2% / Spironolactone 5% …
Matched Categories: … Potassium-Sparing Diuretics ... P-glycoprotein inducers ... Cytochrome P-450 CYP2C8 Inhibitors ... Cytochrome P-450 Enzyme Inhibitors ... Cytochrome P-450 CYP2C8 Inhibitors (moderate) …

Pheneticillin

Pheneticillin (or phenethicillin) is a penicillin antibiotic which is approved for use internationally.
Approved
Matched Iupac: … (2S,5R,6R)-3,3-dimethyl-7-oxo-6-(2-phenoxypropanamido)-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic ... acid …
Matched Salts cas: … 132-93-4 …
Matched Salts name: … Pheneticillin potassium …

Docusate

Docusate, or dioctyl sulfosuccinate, is a stool softener indicated for the treatment of constipation . Docusate acts by increasing the amount of water the stool absorbs in the gut, making the stool softer and easier to pass . Docusate can be orally or rectally administered. Docusate is on the World...
Approved
Matched Iupac: … 1,4-bis[(2-ethylhexyl)oxy]-1,4-dioxobutane-2-sulfonic acid …
Matched Salts cas: … 128-49-4 ... 577-11-7 ... 7491-09-0 …
Matched Mixtures name: … PNV Ferrous Fumarate Docusate Folic Acid ... VemaVite-PRx 2 with Fish-Based DHA ... Prenatal Vitamin No 53 Iron Fum Folic Acid Docusate CA DHA …
Matched Salts name: … Docusate potassium …
Matched Products: … Doxate-S Cap 100mg USP ... Jamp Docusate S Oblong …

Loperamide

Loperamide is an anti-diarrheal agent that is available as various over-the-counter products for treating diarrhea. The drug was first synthesized in 1969 and used medically in 1976. It is a highly lipophilic synthetic phenylpiperidine opioid that is structurally similar to opiate receptor agonists such as diphenoxylate and haloperidol. Due to...
Approved
Matched Iupac: … 4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-N,N-dimethyl-2,2-diphenylbutanamide …
Matched Salts cas: … 34552-83-5 …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... P-glycoprotein substrates ... Cytochrome P-450 Substrates ... Cytochrome P-450 CYP2B6 Substrates ... Cytochrome P-450 CYP3A Inhibitors …
Matched Products: … DIATROL SYRUP 1 mg/5 ml ... Anti-Diarrheal 24/7 for Life by 7-Eleven ... 7 Select Anti Diarrheal …

Fluoxymesterone

An anabolic steroid that has been used in the treatment of male hypogonadism, delayed puberty in males, and in the treatment of breast neoplasms in women.
Approved
Illicit
Matched Synonyms: … 11β,17β-Dihydroxy-9α-fluoro-17α-methyl-4-androster-3-one ... 9-Fluoro-11β,17β-dihydroxy-17-methylandrost-4-en-3-one …
Matched Iupac: … dihydroxy-1,9a,11a-trimethyl-1H,2H,3H,3aH,3bH,4H,5H,7H,8H,9H,9aH,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-7- …
Matched Categories: … 3-Oxoandrosten (4) Derivatives …

Patiromer

Patiromer is a powder for suspension in water for oral administration, approved in the U.S. as Veltassa in October, 2015. Patiromer is supplied as patiromer sorbitex calcium which consists of the active moiety, patiromer, a non-absorbed potassium-binding polymer, and a calcium-sorbitol counterion. Each gram of patiromer is equivalent to a...
Approved
Investigational
Matched Description: … supplied as patiromer sorbitex calcium which consists of the active moiety, patiromer, a non-absorbed potassium-binding ... The chemical name for patiromer sorbitex calcium is cross-linked polymer of calcium 2-fluoroprop-2-enoate ... Each gram of patiromer is equivalent to a nominal amount of 2 grams of patiromer sorbitex calcium. …
Matched Categories: … Potassium Binder ... Potassium-removing Agents ... Potassium Ion Binding Activity …

Calcium glycerophosphate

Calcium glycerophosphate is a DB01373 salt of glycerophosphoric acid that forms a white, fine, slightly hygroscopic powder. The commercial product is a mixture of calcium beta-, and D-, and L -alpha-glycerophosphate. By FDA, calcium glycerophosphate is considered a generally recognized as safe (GRAS) food ingredient as a nutrient supplement (source...
Approved
Matched Synonyms: … β-glycerophosphoric acid calcium salt …
Matched Iupac: … calcium 2-(phosphonooxy)propane-1,3-diol …
Matched Description: … Calcium glycerophosphate is a [DB01373] salt of glycerophosphoric acid that forms a white, fine, slightly …

Pemirolast

Pemirolast potassium is a slightly yellow powder that is soluble in water. It is a mast cell stabilizer that acts as an antiallergic agent. As an ophthalmic aqueous sterile solution, pemirolast is used for the prevention of itching of the eyes caused by allergies such as hay fever, and allergic...
Approved
Investigational
Matched Iupac: … 9-methyl-3-(2H-1,2,3,4-tetrazol-5-yl)-4H-pyrido[1,2-a]pyrimidin-4-one …
Matched Description: … Pemirolast potassium is a slightly yellow powder that is soluble in water. …
Matched Salts name: … Pemirolast potassium …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Metamizole

Metamizole (dipyrone) is a pyrazolone derivative that belongs to the group of nonacid nonopioids. It is considered a potent analgesic and antipyretic with favourable gastrointestinal tolerability. Metamizole was formerly marketed in the US as Dimethone tablets and injection, Protemp oral liquid, and other drug products, and was withdrawn due to...
Approved
Investigational
Withdrawn
Matched Iupac: … [(1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)(methyl)amino]methanesulfonic acid …
Matched Salts cas: … 68-89-3 ... 6150-97-6 ... 5907-38-0 …
Matched Mixtures name: … DIPIRONA 2.5 G + HIOSCINA 20 MG/5 ML SOLUCION INYECTABLE ... N-BUTIL BROMURO DE HIOSCINA20MG + DIPIRONA 2500 MG/5 ML ... DIPIRONA 2.5 G + HIOSCINA 20 MG/5 ML SOLUCION INYECTABLE …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Cytochrome P-450 CYP2B6 Inducers ... Cytochrome P-450 CYP3A Inducers ... Cytochrome P-450 CYP3A4 Inducers ... Cytochrome P-450 Enzyme Inducers …
Matched Products: … PRECIDONA-S ... DEVALJİN 1 G/2 ML I.M./I.V. ENJEKSİYONLUK ÇÖZELTİ İÇEREN AMPUL 5 AMPUL ... METAMIZOL 1 G/2 ML IM/IV ENJEKSİYON İÇİN ÇÖZELTİ İÇEREN AMPUL, 5 ADET …

Magnesium

Magnesium is classified as an alkaline earth metal and has 2 hydration shells. The element can be found in abundance in the hydrosphere and in mineral salts such as dolomite and magnesium carbonate. Common dietary sources of magnesium include nuts (cashews, peanuts, almonds), beans, bananas, apples, carrots, broccoli, and leafy...
Approved
Experimental
Investigational
Matched Description: … Magnesium is classified as an alkaline earth metal and has 2 hydration shells. …
Matched Mixtures name: … Cal/mag 2:1 With D ... Acti-cal/mag 2:1 + Zinc and D Caplet ... Chelated Cal-mag(2:1)with Zn Vit.c and D …
Matched Products: … Kordel’s Magnesium Amino Acid Chelate 750 Capsules ... MG 5 LONGORAL ... Emgecard 5 mmol - Granulat …

Somatotropin

Human growth hormone (HGH), also known as somatotropin, is a peptide hormone that is synthesized and secreted by the somatotropic cells of the anterior pituitary gland. Growth hormone plays an essential role in growth regulation during childhood as well as other basal metabolic functions, muscle and fat mass regulation, blood...
Approved
Investigational
Matched Description: … acid residues with a molecular weight of 22 kDa. ... Synthesized in a strain of _Escherichia coli_, recombinant HGH is a polypeptide hormone that contains 191 amino …
Matched Categories: … Amino Acids, Peptides, and Proteins ... P-glycoprotein substrates ... Cytochrome P-450 CYP1A2 Inducers ... Cytochrome P-450 Enzyme Inducers ... Cytochrome P-450 CYP2C19 Inhibitors …
Matched Products: … SAIZEN 4 IU FLAKON, 1 ADET ... GROWTROPINAQ 16 U /2 ML INYECTABLE ... HUMATROPE 18 IU (6 MG) LIYOFILIZE TOZ ICEREN KARTUS, 1 ADET …

Sodium fluoride

Sodium fluoride is an inorganic chemical compound that is a source of the fluoride ion in many applications, including dental care and radiographic imaging when it is used as Fluoride ion F-18. Sodium fluoride's benefits on dental health were first observed in the 1930s, when individuals in communities with fluoridated...
Approved
Matched Mixtures name: … PREVENT 2 EN 1 ... DOCTRUST ONE S Tooth ... 4 Pack …
Matched Products: … Crest Complete Plus 3 in 1 ... Amino Acid Fragrancemouthwash Dawn ... Amino Acid Fragrancemouthwash Blossom …

Prucalopride

Prucalopride is a dihydrobenzofurancarboxamide derivative from the benzofurane family that selectively stimulates 5-HT4 receptors and thus, it presents enterokinetic properties. The high selectivity of prucalopride allowed further development as it prevented the cardiac adverse reactions observed due to non-target effects of precedent therapies. Prucalopride was developed by Shire Development LLC...
Approved
Matched Iupac: … 4-amino-5-chloro-N-[1-(3-methoxypropyl)piperidin-4-yl]-2,3-dihydro-1-benzofuran-7-carboxamide …
Matched Description: … is a dihydrobenzofurancarboxamide derivative from the benzofurane family that selectively stimulates 5- ... developed by Shire Development LLC and approved for use in Europe in 2009,[A40250] in Canada on December 7, …
Matched Salts cas: … 179474-80-7 ... 179474-85-2 …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... Serotonin 5-HT4 Receptor Agonists ... Serotonin-4 Receptor Agonist ... Serotonin 4 Receptor Agonists ... Cytochrome P-450 Substrates …
Matched Products: … Resolor Film-coated Tablet 2 mg ... Resolor Film-coated Tablet 1 mg ... RESOLOR ® TABLETAS RECUBIERTAS DE 2 MG …

Amifampridine

Amifampridine, or 3,4-diaminopyridine (3,4-DAP), is a quaternary ammonium compound that blocks presynaptic potassium channels, and subsequently prolongs the action potential and increases presynaptic calcium concentrations . It was first discovered in Scotland in the 1970s and its clinical effectiveness for neuromuscular disorders, including Lambert–Eaton myasthenic syndrome (LEMS), has been investigated...
Approved
Investigational
Matched Description: … Amifampridine, or 3,4-diaminopyridine (3,4-DAP), is a quaternary ammonium compound that blocks presynaptic potassium ... Patients with LEMS develop serum antibodies against presynaptic P/Q-type voltage-gated calcium channels …
Matched Salts cas: … 446254-47-3 …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Potassium Channel Blockers …
Displaying drugs 226 - 250 of 332 in total