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Displaying drugs 2651 - 2675 of 9732 in total

Human papillomavirus type 6 L1 capsid protein antigen

Human papillomavirus type 6 L1 capsid protein antigen is contained in Gardasil, or a recombinant Human Papillomavirus Quadrivalent (Types 6, 11, 16, and 18) vaccine for intramuscular injection. It is an immunization for young men and women 9-26 years of age for the prevention of diseases caused by Human Papillomavirus...
Approved
Investigational
Matched Description: … of HPV Types 6, 11, 16, and 18, which are produced by separate fermentations in recombinant *Saccharomyces ... by Human Papillomavirus (HPV) types 6, 11, 16 and 18. ... It is an immunization for young men and women 9-26 years of age for the prevention of diseases caused …

Human papillomavirus type 16 L1 capsid protein antigen

Human papillomavirus type 16 L1 capsid protein antigen is contained in Gardasil, or a recombinant Human Papillomavirus Quadrivalent (Types 6, 11, 16, and 18) vaccine for intramuscular injection. It is an immunization for young men and women 9-26 years of age for the prevention of diseases caused by Human Papillomavirus...
Approved
Investigational
Matched Description: … of HPV Types 6, 11, 16, and 18, which are produced by separate fermentations in recombinant *Saccharomyces ... by Human Papillomavirus (HPV) types 6, 11, 16 and 18. ... It is an immunization for young men and women 9-26 years of age for the prevention of diseases caused …

Sildenafil

In eliciting its mechanism of action, sildenafil ultimately prevents or minimizes the breakdown of cyclic guanosine monophosphate (cGMP) by inhibiting cGMP specific phosphodiesterase type 5 (PDE5) [F3850, F3853, F3856, F3859, F3883, F3886, L5611, L5614]. The result of doing so allows cGMP present in both the penis and pulmonary vasculature to...
Approved
Investigational
Matched Description: … In eliciting its mechanism of action, sildenafil ultimately prevents or minimizes the breakdown of cyclic ... The result of doing so allows cGMP present in both the penis and pulmonary vasculature to elicit smooth ... Nevertheless, it is because of this mechanism that sildenafil is also indicated for treating pulmonary …
Matched Mixtures name: … DAPOXIL 30/50 MG FILM KAPLI TABLET,18 FILM KAPLI TABLET …
Matched Categories: … combinations of sulfonamides …
Matched Products: … Sildenafil R ... PMS-sildenafil R ... Apo-sildenafil R …

Pheneticillin

Pheneticillin (or phenethicillin) is a penicillin antibiotic which is approved for use internationally.
Approved
Matched Categories: … combinations of penicillins …

Theophylline

A methylxanthine derivative from tea with diuretic, smooth muscle relaxant, bronchial dilation, cardiac and central nervous system stimulant activities. Mechanistically, theophylline acts as a phosphodiesterase inhibitor, adenosine receptor blocker, and histone deacetylase activator. Theophylline is marketed under several brand names such as Uniphyl and Theochron, and it is indicated mainly...
Approved
Matched Categories: … combinations of xanthines …
Matched Products: … TEOFILINA R ® 200 MG ... TEOFILINA R CAPSULAS 100 MG ... DIFFUMAL R 200 MG TABLET, 30 ADET …

Tolvaptan

Tolvaptan is used to treat low blood sodium levels (hyponatremia) associated with various conditions like congestive heart failure, cirrhosis, and syndrome of inappropriate antidiuretic hormones (SIADH). FDA approved on May 19, 2009.
Approved
Matched Description: … hyponatremia) associated with various conditions like congestive heart failure, cirrhosis, and syndrome of …

Omidenepag isopropyl

Omidenepag isopropyl is a topical ocular hypotensive agent used to reduce intraocular pressure (IOP) in patients with glaucoma and ocular hypertension. Omidenepag isopropyl is quickly metabolized to its active metabolite, omidenepag, a molecule with high selectivity and agonistic activity towards the prostaglandin E2 (EP2) receptor.[A253263,A253268] Prostanoid FP receptor agonists (FP...
Approved
Investigational
Matched Description: … [A253268] In September 2022, the FDA approved the use of omidenepag isopropyl.[L43503] ... The use of an EP2 receptor agonist such as omidenepag represents an alternative in these scenarios. ... [A253263,A253268] Prostanoid FP receptor agonists (FP agonists), such as [latanoprost], are part of the …
Matched Categories: … combinations of sulfonamides …

Eladocagene exuparvovec

Eladocagene exuparvovec is a recombinant adeno-associated virus-2 (AAV2)-based gene therapy that expresses human aromatic L-amino acid decarboxylase (AADC), and it is used to treat AADC deficiency, a fatal and rare genetic disorder that causes severe disability in pediatric patients.[L43642,L43672] Patients with AADC have mutations in the dopa decarboxylase (DDC) gene...
Approved
Investigational
Matched Description: … By promoting the expression of AADC, eladocagene exuparvovec leads to the development of motor function ... [A253697,L43672] Before the approval of this gene therapy, the treatment options for patients with AADC …

Oxazepam

Oxazepam is an intermediate-acting, 3-hydroxybenzodiazepine used in the treatment of alcohol withdrawal and anxiety disorders. Oxazepam, like related 3-hydroxybenzodiazepine lorazepam, is considered less susceptible to pharmacokinetic variability based on patient-specific factors (e.g. age, liver disease) - this feature is advantageous as compared to other benzodiazepines, and is likely owing in...
Approved
Matched Description: … Oxazepam is an intermediate-acting, 3-hydroxybenzodiazepine used in the treatment of alcohol withdrawal ... [A203516] It is an active metabolite of both [diazepam] and [temazepam][A39486] and undergoes very little …

Reboxetine

Reboxetine is an antidepressant drug used in the treatment of clinical depression, panic disorder and ADD/ADHD. Its mesylate (i.e. methanesulfonate) salt is sold under tradenames including Edronax, Norebox, Prolift, Solvex, Davedax or Vestra. Reboxetine has two chiral centers, but it only exists as two enantiomers, (R,R)-(-)- and (S,S)-(+)-reboxetine.
Approved
Experimental
Matched Iupac: … (2R)-2-[(R)-(2-ethoxyphenoxy)(phenyl)methyl]morpholine …
Matched Description: … Reboxetine is an antidepressant drug used in the treatment of clinical depression, panic disorder and ... Reboxetine has two chiral centers, but it only exists as two enantiomers, (R,R)-(-)- and (S,S)-(+)-reboxetine …

Rabies immune globulin, human

IMOGAM Rabies Pasteurized is indicated for post-exposure prophylaxis in persons suspected of exposure to rabies, who have not previously received a complete immunization regimen with a cell culture produced rabies vaccine. Persons previously vaccinated with other types of rabies vaccines in whom adequate antibody levels have not been demonstrated should...
Approved
Matched Description: … IMOGAM Rabies Pasteurized is indicated for post-exposure prophylaxis in persons suspected of exposure ... Persons previously vaccinated with other types of rabies vaccines in whom adequate antibody levels have ... If IMOGAM Rabies Pasteurized is not administered as recommended at the initiation of the post-exposure …
Matched Products: … BERIRAB(R) P …

Etodolac

Etodolac is a non-steroidal anti-inflammatory drug (NSAID) with anti-inflammatory, analgesic and antipyretic properties. Its therapeutic effects are due to its ability to inhibit prostaglandin synthesis. It is indicated for relief of signs and symptoms of rheumatoid arthritis and osteoarthritis.
Approved
Investigational
Vet approved
Matched Description: … It is indicated for relief of signs and symptoms of rheumatoid arthritis and osteoarthritis. …

Mavacamten

Mavacamten is a myosin inhibitor indicated for the treatment of adults with symptomatic New York Heart Association (NYHA) class II-III obstructive hypertrophic cardiomyopathy (HCM). It received initial US FDA approval in 2022, and it is one of the first myosin inhibitors to be used in humans. Mavacamten was also approved...
Approved
Investigational
Matched Description: … Mavacamten is a myosin inhibitor indicated for the treatment of adults with symptomatic New York Heart ... It received initial US FDA approval in 2022, and it is one of the first myosin inhibitors to be used …

Prednicarbate

Prednicarbate is a relatively new topical corticosteroid drug that displays a similar potency as hydrocortisone. It is used in the treatment of inflammatory skin diseases, such as atopic dermatitis. It has a favorable benefit-risk ratio, with an inflammatory action similar to that of a medium potency corticosteroid, but with a...
Approved
Investigational
Matched Description: … The anti-inflammation action of corticosteroids is associated with the inhibition of the interleukin ... It is used in the treatment of inflammatory skin diseases, such as atopic dermatitis. ... It has a favorable benefit-risk ratio, with an inflammatory action similar to that of a medium potency …
Matched Products: … DERMATOP (R) CREAM …

Glymidine

Glycodiazine is used with diet to lower blood glucose by increasing the secretion of insulin from pancreas and increasing the sensitivity of peripheral tissues to insulin. The mechanism of action of glycodiazine in lowering blood glucose appears to be dependent on stimulating the release of insulin from functioning pancreatic beta...
Approved
Investigational
Matched Description: … The mechanism of action of glycodiazine in lowering blood glucose appears to be dependent on stimulating ... the release of insulin from functioning pancreatic beta cells, and increasing sensitivity of peripheral ... and increasing the sensitivity of peripheral tissues to insulin. …
Matched Categories: … combinations of sulfonamides …

D-glucose

Glucose is a simple sugar (monosaccharide) generated during phosynthesis involving water, carbon and sunlight in plants. It is produced in humans via hepatic gluconeogenesis and breakdown of polymeric glucose forms (glycogenolysis). It circulates in human circulation as blood glucose and acts as an essential energy source for many organisms through...
Approved
Investigational
Vet approved
Matched Description: … Its aldohexose stereoisomer, dextrose or D-glucose, is the most commonly occurring isomer of glucose ... It is produced in humans via hepatic gluconeogenesis and breakdown of polymeric glucose forms (glycogenolysis ... [T28] The unspecified form of glucose is commonly supplied as an injection for nutritional supplementation …
Matched Mixtures name: … Reveos Select CPD/AS-5 Red Cell Preservative For Collection Of Blood ... CAPD 18 ... CAPD 18 …

Butoconazole

Butoconazole is an imidazole antifungal used in gynecology.
Approved
Matched Categories: … combinations of imidazole derivatives …

Sodium cellulose phosphate

Sodium cellulose phosphate is used to treat hypercalcemia and hypercalciuria. It has been used to prevent kidney stones. This compound is an ion-exchange resin that can not be absorbed by the body. However, it can be used to restore normal intestinal calcium absorption.
Approved
Matched Categories: … Drugs for Treatment of Hypercalcemia …

Tiludronic acid

Tiludronate, or (4-chlorophenyl)thio-methylene-1,1-bisphosphonate, is a first generation bisphosphonate similar to etidronic acid and clodronic acid.[A1923,A203111] These drugs were developed to mimic the action of pyrophosphate, a regulator of calcification and decalcification. Tiludronic acid was first described in the literature in 1988 as a potential treatment for Paget's disease of bone....
Approved
Investigational
Vet approved
Matched Description: … [A1923,A203111] These drugs were developed to mimic the action of pyrophosphate, a regulator of calcification ... Tiludronic acid was first described in the literature in 1988 as a potential treatment for Paget's disease of …
Matched Categories: … Drugs for Treatment of Bone Diseases …

Diclofenamide

A carbonic anhydrase inhibitor that is used in the treatment of glaucoma.
Approved
Investigational
Matched Description: … A carbonic anhydrase inhibitor that is used in the treatment of glaucoma. …
Matched Categories: … combinations of sulfonamides …

Mazindol

Mazindol is a tricyclic anorexigenic agent that is unrelated to and less toxic than amphetamine, but with some similar side effects. It inhibits uptake of catecholamines and blocks the binding of cocaine to the dopamine uptake transporter. Mazindol is only approved in the United States for the treatment of Duchenne...
Approved
Investigational
Matched Description: … It inhibits uptake of catecholamines and blocks the binding of cocaine to the dopamine uptake transporter ... is not marketed or available in the United States for use in the treatment of obesity. ... Mazindol is only approved in the United States for the treatment of Duchenne muscular dystrophy, and …
Matched Categories: … Combined Inhibitors of Serotonin/Norepinephrine Reuptake ... Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …

Lymecycline

Lymecycline is a broad-spectrum second-generation tetracycline antibiotic used for the treatment of acne and other susceptible bacterial infections.[L13880,L13883] It has been proven a cost-effective alternative to treatment with minocycline with comparable safety and efficacy. Lymecycline was initially discovered in 1961. It is marketed by Galderma and used in the UK...
Approved
Investigational
Matched Description: … Lymecycline is a broad-spectrum second-generation tetracycline antibiotic used for the treatment of acne …
Matched Categories: … combinations of tetracyclines …

Methohexital

An intravenous anesthetic with a short duration of action that may be used for induction of anesthesia.
Approved
Matched Description: … An intravenous anesthetic with a short duration of action that may be used for induction of anesthesia …
Matched Categories: … combinations of barbiturates …

Rolitetracycline

A pyrrolidinylmethyl tetracycline.
Approved
Matched Categories: … combinations of tetracyclines …

Propyliodone

Radiopaque medium usually in oil; used in bronchography.
Approved
Matched Categories: … Diagnostic Uses of Chemicals …
Displaying drugs 2651 - 2675 of 9732 in total