Displaying drugs 251 - 275 of 646 in total
Glycopyrronium
Glycopyrronium, also known as NVA237 or glycopyrrolate, is a racemic mixture of two enantiomers. They are both quaternary ammonium compounds and long acting muscarinic antagonists. It is one of the most commonly prescribed anticholinergic medications.[A233535,A233540] Early research into glycopyrronium use was for its indication as an adjunct therapy in the...
Approved
Investigational
Vet approved
Matched Salts name: … Glycopyrronium bromide …
Matched Categories: … glycopyrronium bromide ... glycopyrronium bromide ... formoterol and glycopyrronium bromide ... indacaterol and glycopyrronium bromide ... glycopyrronium bromide and psycholeptics …
Matched Categories: … glycopyrronium bromide ... glycopyrronium bromide ... formoterol and glycopyrronium bromide ... indacaterol and glycopyrronium bromide ... glycopyrronium bromide and psycholeptics …
Bumetanide
Bumetanide is a sulfamyl diuretic.
Approved
Matched Categories: … bumetanide and potassium ... Non Potassium Sparing Diuretics ... bumetanide and potassium-sparing agents ... Sodium Potassium Chloride Symporter Inhibitors ... High-Ceiling Diuretics and Potassium-Sparing Agents …
Umeclidinium
Umeclidinium is a long-acting muscarinic antagonist (LAMA) used as a maintenance treatment for symptoms of chronic obstructive pulmonary disease (COPD). COPD is a progressive obstructive lung disease characterized by shortness of breath, cough, sputum production, and chronically poor airflow with a forced expiratory volume in 1 second (FEV1) of less...
Approved
Matched Salts name: … Umeclidinium bromide …
Matched Categories: … umeclidinium bromide ... vilanterol and umeclidinium bromide ... vilanterol, umeclidinium bromide and fluticasone furoate …
Matched Categories: … umeclidinium bromide ... vilanterol and umeclidinium bromide ... vilanterol, umeclidinium bromide and fluticasone furoate …
Cyclopenthiazide
Cyclopenthiazide is a thiazide diuretic with antihypertensive properties. In a double blind, randomized crossover study, cyclopenthiazide was effective in reducing diastolic blood pressure in mildly hypertensive non-insulin dependent diabetic patients . It is a positive allosteric modulator at AMPA-A receptors .
Approved
Matched Categories: … cyclopenthiazide and potassium ... cyclopenthiazide and potassium-sparing agents ... Low-Ceiling Diuretics and Potassium-Sparing Agents …
D-glucose
Glucose is a simple sugar (monosaccharide) generated during phosynthesis involving water, carbon and sunlight in plants. It is produced in humans via hepatic gluconeogenesis and breakdown of polymeric glucose forms (glycogenolysis). It circulates in human circulation as blood glucose and acts as an essential energy source for many organisms through...
Approved
Investigational
Vet approved
Matched Mixtures name: … Potassium Chloride ... Potassium Chloride ... Potassium Chloride in Dextrose …
Magnesium sulfate
A small colorless crystal used as an anticonvulsant, a cathartic, and an electrolyte replenisher in the treatment of pre-eclampsia and eclampsia. It causes direct inhibition of action potentials in myometrial muscle cells. Excitation and contraction are uncoupled, which decreases the frequency and force of contractions. (From AMA Drug Evaluations Annual,...
Approved
Investigational
Vet approved
Matched Mixtures name: … Sodium Sulfate, Potassium Sulfate, Magnesium Sulfate ... Sodium Sulfate, Potassium Sulfate, Magnesium Sulfate ... Sodium Sulfate, Potassium Sulfate and Magnesium Sulfate …
Sodium bicarbonate
Sodium bicarbonate is a white, crystalline powder that is commonly used as a pH buffering agent, an electrolyte replenisher, systemic alkalizer and in topical cleansing solutions.
Approved
Matched Mixtures name: … Prismasol 2 mmol/l Potassium ... Duosol without Potassium Solution for Haemofiltration ... multiBic® 2 mmol/L potassium Solution for Haemofiltration …
Sodium phosphate, dibasic
Approved
Matched Mixtures name: … Dibasic Sodium Phosphate, Monobasic Potassium Phosphate and Monobasic Sodium Phosphate ... Dibasic Sodium Phosphate, Monobasic Potassium Phosphate and Monobasic Sodium Phosphate ... Dibasic Sodium Phosphate, Monobasic Potassium Phosphate and Monobasic Sodium Phosphate …
Magnesium
Magnesium is classified as an alkaline earth metal and has 2 hydration shells. The element can be found in abundance in the hydrosphere and in mineral salts such as dolomite and magnesium carbonate. Common dietary sources of magnesium include nuts (cashews, peanuts, almonds), beans, bananas, apples, carrots, broccoli, and leafy...
Approved
Experimental
Investigational
Matched Mixtures name: … Calcium & Magnesium Plus Potassium & Zinc ... Calcium & Magnesium With Potassium & Zinc ... Calcium & Magnesium Plus Potassium & Zinc …
Aluminum zirconium octachlorohydrex gly
Aluminum zirconium octachlorohydrex gly is complex that consists of aluminum zirconium octachlorohydrate and glycine. It is an active antiperspirant agent , . It diffuses into the sweat pores and prevents perspiration (sweat) from leaving the pores. The anhydrous form of the compound also has water-absorbing properties. Currently, the FDA allows...
Approved
Aminobenzoic acid
A member of the vitamin B complex. It used to be common in sunscreening agents until found to also be a sensitizer. The potassium salt is used therapeutically in fibrotic skin disorders.
Approved
Experimental
Matched Description: … The potassium salt is used therapeutically in fibrotic skin disorders. …
Matched Salts name: … Aminobenzoate potassium …
Matched Categories: … aminobenzoate potassium …
Matched Salts name: … Aminobenzoate potassium …
Matched Categories: … aminobenzoate potassium …
Glyburide
Glyburide is a second generation sulfonylurea used to treat patients with diabetes mellitus type II. It is typically given to patients who cannot be managed with the standard first line therapy, metformin. Glyburide stimulates insulin secretion through the closure of ATP-sensitive potassium channels on beta cells, raising intracellular potassium and...
Approved
Matched Description: … on beta cells, raising intracellular potassium and calcium ion concentrations. ... [L8123] Glyburide stimulates insulin secretion through the closure of ATP-sensitive potassium channels …
Pheneticillin
Pheneticillin (or phenethicillin) is a penicillin antibiotic which is approved for use internationally.
Approved
Matched Salts name: … Pheneticillin potassium …
Cyclothiazide
As a diuretic, cyclothiazide inhibits active chloride reabsorption at the early distal tubule via the Na-Cl cotransporter, resulting in an increase in the excretion of sodium, chloride, and water. Thiazides like cyclothiazide also inhibit sodium ion transport across the renal tubular epithelium through binding to the thiazide sensitive sodium-chloride transporter....
Approved
Matched Description: … This results in an increase in potassium excretion via the sodium-potassium exchange mechanism. ... carbonic anhydrases in the smooth muscle or through its action on the large-conductance calcium-activated potassium …
Matched Categories: … cyclothiazide and potassium …
Matched Categories: … cyclothiazide and potassium …
Spironolactone
Spironolactone is a potassium-sparing diuretic. It binds to mineralocorticoid receptors and functions as aldosterone antagonists. It promotes sodium and water excretion and potassium retention. Spironolactone was originally developed purely for this ability before other pharmacodynamic properties of the drug were discovered.[A11837, A178246] It is indicated to treat several conditions, including...
Approved
Matched Description: … Spironolactone is a potassium-sparing diuretic. ... [A178192] It promotes sodium and water excretion and potassium retention. …
Matched Categories: … Potassium-Sparing Diuretics …
Matched Categories: … Potassium-Sparing Diuretics …
Bretylium
Bretylium blocks the release of noradrenaline from the peripheral sympathetic nervous system, and is used in emergency medicine, cardiology, and other specialties for the acute management of ventricular tachycardia and ventricular fibrillation. The primary mode of action for bretylium is thought to be inhibition of voltage-gated K(+) channels. Recent evidence...
Approved
Pinacidil
Pinacidil is a cyanoguanidine drug that acts by opening ATP-sensitive potassium channels, leading to peripheral vasodilatation of arterioles and decreasing peripheral vascular resistance. The above processes result in reduced blood pressure. This drug has been discontinued by the FDA.
Approved
Matched Description: … Pinacidil is a cyanoguanidine drug that acts by opening ATP-sensitive potassium channels, leading to …
Matched Categories: … Potassium Channel Opener …
Matched Categories: … Potassium Channel Opener …
Docusate
Docusate, or dioctyl sulfosuccinate, is a stool softener indicated for the treatment of constipation . Docusate acts by increasing the amount of water the stool absorbs in the gut, making the stool softer and easier to pass . Docusate can be orally or rectally administered. Docusate is on the World...
Approved
Matched Salts name: … Docusate potassium …
Amifampridine
Amifampridine, or 3,4-diaminopyridine (3,4-DAP), is a quaternary ammonium compound that blocks presynaptic potassium channels, and subsequently prolongs the action potential and increases presynaptic calcium concentrations . It was first discovered in Scotland in the 1970s and its clinical effectiveness for neuromuscular disorders, including Lambert–Eaton myasthenic syndrome (LEMS), has been investigated...
Approved
Investigational
Matched Description: … Amifampridine, or 3,4-diaminopyridine (3,4-DAP), is a quaternary ammonium compound that blocks presynaptic potassium …
Matched Categories: … Potassium Channel Blockers …
Matched Categories: … Potassium Channel Blockers …
Calcium gluconate
Calcium gluconate is used as mineral supplement and medication when there is insufficient calcium in the diet. Supplementation may be done to treat or prevent osteoporosis or rickets, consequences of hypocalcemia. It can also be taken by mouth but is not recommended by injection into a muscle.
Calcium Gluconate Injection,...
Approved
Vet approved
Benzoin
Benzoin is a white crystalline compound prepared by condensation of benzaldehyde in potassium cyanide, and is used in organic syntheses. This should not be confused with benzoin gum from STYRAX (see DB11222). Benzoin is an FDA-approved colour additive used for marking fruits and vegetables.
Approved
Experimental
Matched Description: … Benzoin is a white crystalline compound prepared by condensation of benzaldehyde in potassium cyanide …
Ethinylestradiol
Ethinylestradiol was first synthesized in 1938 by Hans Herloff Inhoffen and Walter Hohlweg at Schering. It was developed in an effort to create an estrogen with greater oral bioavailability. These properties were achieved by the substitution of an ethinyl group at carbon 17 of estradiol. Ethinylestradiol soon replaced mestranol in...
Approved
Calcium chloride
Calcium chloride is an ionic compound of calcium and chlorine. It is highly soluble in water and it is deliquescent. It is a salt that is solid at room temperature, and it behaves as a typical ionic halide. It has several common applications such as brine for refrigeration plants, ice...
Approved
Matched Mixtures name: … Potassium Chloride and Dextrose ... Prismasol 2 mmol/l Potassium ... Potassium Chlor 40meq 5% Dex & Lac Ring …
Oxyphenonium
A quaternary ammonium anticholinergic agent with peripheral side effects similar to those of atropine. It is used as an adjunct in the treatment of gastric and duodenal ulcer, and to relieve visceral spasms. The drug has also been used in the form of eye drops for mydriatic effect. [PubChem]
Approved
Matched Salts name: … Oxyphenonium bromide …
Displaying drugs 251 - 275 of 646 in total