Displaying drugs 3451 - 3475 of 8030 in total
Hypromellose
Hypromellose, or hydroxypropyl methylcellulose (HPMC) , is a semisynthetic, inert, and viscoelastic polymer that forms a colloid solution when dissolved in water. It acts as a thickening agent, coating polymer, bioadhesive, solubility enhancer in solid dispersions, and binder in the process of granulation and in modified release formulations . It...
Approved
Matched Description: … a drug in a controlled fashion, effectively increasing the duration of release of a drug to prolong ... , coating polymer, bioadhesive, solubility enhancer in solid dispersions, and binder in the process of ... is a commonly used as a delivery component in oral pharmaceutical products that provides the release of …
Anthoxanthum odoratum
Anthoxanthum odoratum allergenic extract is used in allergenic testing.
Approved
Interferon gamma-1b
Human Interferon gamma-1b (140 residues), produced from E. coli. Production of Actimmune is achieved by fermentation of a genetically engineered Escherichia coli bacterium containing the DNA which encodes for the human protein. Purification of the product is achieved by conventional column chromatography.
The sequence displayed is a cDNA sequence which...
Approved
Investigational
Matched Description: … Production of Actimmune is achieved by fermentation of a genetically engineered Escherichia coli bacterium ... Purification of the product is achieved by conventional column chromatography. …
Methantheline
Methantheline is a synthetic antispasmodic. Antispasmodics are used to relieve cramps or spasms of the stomach, intestines, and bladder. Methantheline is used to treat intestine or stomach ulcers (peptic ulcer disease), intestine problems (irritable bowel syndrome), pancreatitis, gastritis, biliary dyskinesia, pylorosplasm, or urinary problems (reflex neurogenic bladder in children).
Approved
Investigational
Matched Description: … Antispasmodics are used to relieve cramps or spasms of the stomach, intestines, and bladder. …
Ichthammol
Ichthammol is also referred to as ammonium bituminosulfonate or ammonium bituminosulphonate. It is an ammonium salt of dark sulfonated shale oil (bituminous schists) produced via distillation of the oil followed by sulfonation and neutralization. It is available in OTC products as an active ingredient for the treatment of skin disorders...
Approved
Matched Description: … It is an ammonium salt of dark sulfonated shale oil (bituminous schists) produced via distillation of ... It is available in OTC products as an active ingredient for the treatment of skin disorders such as eczema …
Nitrogen
Nitrogen is a chemical element with symbol N and atomic number 7. At room temperature, it is a transparent, odorless diatomic gas.
Liquid nitrogen is used principally in cryotherapy for removal of diseased skin. Liquid nitrogen helps in removal of skin lesions through necrosis, which results from the freezing and...
Approved
Vet approved
Matched Description: … thawing of cells. ... Liquid nitrogen is used principally in cryotherapy for removal of diseased skin. ... Liquid nitrogen helps in removal of skin lesions through necrosis, which results from the freezing and …
Lonoctocog alfa
Approved
Investigational
Acetophenazine
Acetophenazine is an antipsychotic drug of moderate-potency. It is used in the treatment of disorganized and psychotic thinking. It is also used to help treat false perceptions (e.g. hallucinations or delusions). It primarily targets the dopamine D2 receptor.
Approved
Matched Description: … Acetophenazine is an antipsychotic drug of moderate-potency. ... It is used in the treatment of disorganized and psychotic thinking. …
Bordetella pertussis toxoid antigen (formaldehyde, glutaraldehyde inactivated)
Bordetella pertussis toxoid antigen (formaldehyde, glutaraldehyde inactivated) is a vaccine that is used in the prophylaxis of Pertussis (whooping cough), which is caused by a small Gram-negative coccobacillus that infects the mucosal layers of the human respiratory tract.
Approved
Matched Description: … toxoid antigen (formaldehyde, glutaraldehyde inactivated) is a vaccine that is used in the prophylaxis of ... whooping cough), which is caused by a small Gram-negative coccobacillus that infects the mucosal layers of …
Crotalus scutulatus antivenin
Crotalus scutulatus antivenin is derived and purified immunoglobulin fragments obtained from other domestic animals such as sheep previously immunized with Crotalus scutulatus (also known as the Mojave rattlesnake ).
The final purified antivenin product is obtained by mixing other different monospecific snake antivenins and isolating the antivenin of interest through...
Approved
Experimental
Matched Description: … Mojave rattlesnakes inhabit desert areas of the southwestern United States and central Mexico. ... product is obtained by mixing other different monospecific snake antivenins and isolating the antivenin of ... Specimens with type A venom, which cause a different pattern of injury than other rattlesnakes, have …
Tilactase
Tilactase is a beta-D-galactosidase obtained from Aspergillus oryzae. It is produced as a chewable tablet that has to be taken before the consumption of a lactose-containing meal. The beta-D-galactosidase us a large monomeric multi-domain enzyme of 985 residues that presents a catalytic (alpha/beta)8-barrel domain. It is considered by the WHO...
Approved
Experimental
Matched Description: … It is produced as a chewable tablet that has to be taken before the consumption of a lactose-containing ... [A27172] The beta-D-galactosidase us a large monomeric multi-domain enzyme of 985 residues that presents ... [A32591] It is considered by the WHO as part of the International Nonpropietary Names for Pharmaceutical …
Exemestane
Exemestane is an oral steroidal aromatase inhibitor used in the adjuvant treatment of hormonally-responsive (also called hormone-receptor-positive, estrogen-responsive) breast cancer in postmenopausal women. It irreversibly binds to the active site of the enzyme resulting in permanent inhibition.
Approved
Investigational
Matched Description: … It irreversibly binds to the active site of the enzyme resulting in permanent inhibition. ... Exemestane is an oral steroidal aromatase inhibitor used in the adjuvant treatment of hormonally-responsive …
Asfotase alfa
Asfotase alfa is a first-in-class bone-targeted enzyme replacement therapy designed to address the underlying cause of hypophosphatasia (HPP)—deficient alkaline phosphatase (ALP). Hypophosphatasia is almost always fatal when severe skeletal disease is obvious at birth. By replacing deficient ALP, treatment with Asfotase Alfa aims to improve the elevated enzyme substrate levels...
Approved
Investigational
Matched Description: … The annual average price of Asfotase Alfa treatment is $285,000. ... a first-in-class bone-targeted enzyme replacement therapy designed to address the underlying cause of ... Asfotase alfa was first approved by Pharmaceuticals and Medicals Devices Agency of Japan (PMDA) on July …
Gastric intrinsic factor
Intrinsic factor (IF), also known as gastric intrinsic factor (GIF), is a glycoprotein produced by the parietal cells of the stomach that is necessary for the absorption of vitamin B12 (cobalamin) later on in the small intestine. When vitamin B12 is provided in combination with intrinsic factor, intrinsic factor reduces...
Approved
Experimental
Matched Description: … IF), also known as gastric intrinsic factor (GIF), is a glycoprotein produced by the parietal cells of ... the stomach that is necessary for the absorption of vitamin B12 (cobalamin) later on in the small intestine ... with cyanocobalamin (synthetic Vitamin B12), ferrous fumarate, and ascorbic acid for the treatment of …
Pancrelipase protease
Pancrelipase, in general, is composed of a mixture of pancreatic enzymes which include amylases, lipases, and proteases. These enzymes are extracted from porcine pancreatic glands. The pancrelipase protease is a mix of enzymes, formed by trypsin and chymotrypsin, that proteolytically cleave peptide bonds and are involved in food digestion.[A32742, L2543]...
Approved
Matched Description: … Pancrelipase, in general, is composed of a mixture of pancreatic enzymes which include amylases, lipases ... [L2509] The pancrelipase protease is a mix of enzymes, formed by trypsin and chymotrypsin, that proteolytically …
Calcium glycerophosphate
Calcium glycerophosphate is a DB01373 salt of glycerophosphoric acid that forms a white, fine, slightly hygroscopic powder. The commercial product is a mixture of calcium beta-, and D-, and L -alpha-glycerophosphate. By FDA, calcium glycerophosphate is considered a generally recognized as safe (GRAS) food ingredient as a nutrient supplement (source...
Approved
Matched Description: … The commercial product is a mixture of calcium beta-, and D-, and L -alpha-glycerophosphate. ... Calcium glycerophosphate is a [DB01373] salt of glycerophosphoric acid that forms a white, fine, slightly ... is considered a generally recognized as safe (GRAS) food ingredient as a nutrient supplement (source of …
Duvelisib
Duvelisib, also known as IPI-145 and INK-1197, is a small-molecule inhibitor of phosphoinositide-3 kinases that was designed initially to prove that simultaneous inhibition of the isoforms delta and gamma can produce a broad adaptative and innate immune cell inhibitory activity. All the work around duvelisib showed that this agent is...
Approved
Investigational
Matched Description: … All the work around duvelisib showed that this agent is a potent inhibitor of both forms. ... Duvelisib, also known as IPI-145 and INK-1197, is a small-molecule inhibitor of phosphoinositide-3 kinases ... that was designed initially to prove that simultaneous inhibition of the isoforms delta and gamma can …
Isopropamide
Isopropamide iodide is a long-acting quaternary anticholinergic drug. It is used in the treatment of peptic ulcer and other gastrointestinal disorders marked by hyperacidity and hypermotility.
Approved
Vet approved
Matched Description: … It is used in the treatment of peptic ulcer and other gastrointestinal disorders marked by hyperacidity …
Pancrelipase lipase
Pancrelipase, in general, is composed of a mixture of pancreatic enzymes which include amylases, lipases, and proteases. These enzymes are extracted from porcine pancreatic glands. The pancrelipase lipase is an enzyme secreted by the pancreas that is responsible for the hydrolysis of dietary fat molecules in the human digestive system....
Approved
Matched Description: … Pancrelipase, in general, is composed of a mixture of pancreatic enzymes which include amylases, lipases ... The pancrelipase lipase is an enzyme secreted by the pancreas that is responsible for the hydrolysis of …
Nitrite
Nitrite is under investigation for the treatment of Heart Failure.
Approved
Investigational
Matched Description: … Nitrite is under investigation for the treatment of Heart Failure. …
Agkistrodon piscivorus antivenin
Agkistrodon piscivorus antivenin is derived and purified immunoglobulin fragments obtained from other domestic animals such as sheep previously immunized with Agkistrodon piscivorus (Cottonmouth or Water Moccasin snake). The final purified antivenin product is obtained by mixing other different monospecific snake antivenins and isolating the antivenin of interest through fractionation and...
Approved
Experimental
Matched Description: … This species of snake is endemic to the United States. ... In North America, members of the family Crotalidae belong to three genera: the rattlesnakes (Crotalus ... Approximately 99% of all venomous snake bites in the United States are caused by Crotalidae, also known …
Allogeneic cultured keratinocytes and dermal fibroblasts in murine collagen
Stratagraft (allogeneic cultured keratinocytes and dermal fibroblasts in murine collagen-dsat) is an allogeneic cellularized scaffold product used for the treatment of adults with thermal burns containing intact dermal elements for which surgical intervention is clinically indicated (also known as deep partial-thickness burns). It was developed as an alternative to autografting...
Approved
Matched Description: … [L35525]
Stratagraft consists of two kinds of lab-grown skin cells, keratinocytes and dermal fibroblasts ... fibroblasts in murine collagen-dsat) is an allogeneic cellularized scaffold product used for the treatment of ... which a patient's own skin is harvested and grafted onto the burn site - which has the disadvantage of …
Seractide acetate
Seractide acetate is the acetate salt of full length human corticotropin.
Approved
Matched Description: … Seractide acetate is the acetate salt of full length human corticotropin. …
Levallorphan
An opioid antagonist with properties similar to those of naloxone; in addition it also possesses some agonist properties. It should be used cautiously; levallorphan reverses severe opioid-induced respiratory depression but may exacerbate respiratory depression such as that induced by alcohol or other non-opioid central depressants. (From Martindale, The Extra Pharmacopoeia,...
Approved
Matched Description: … An opioid antagonist with properties similar to those of naloxone; in addition it also possesses some …
Displaying drugs 3451 - 3475 of 8030 in total