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Displaying drugs 376 - 400 of 14564 in total
Ciprofloxacin is a second generation fluoroquinolone that has spawned many derivative antibiotics. It is formulated for oral, intravenous, intratympanic, ophthalmic, and otic administration for a number of bacterial infections.[L6469,L6472,L6475,L6478,L6481,L6484,L6487,L6490,L6493] The first ciprofloxacin containing product was FDA approved on 22 October 1987.
Approved
Investigational
Matched Synonyms: … 1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic acid ... 1-cyclopropyl-6-fluoro-4-oxo-7-piperazin-1-ylquinoline-3-carboxylic acid ... 1-cyclopropyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylic acid …
Matched Iupac: … 1-cyclopropyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylic acid …
Matched Description: … number of bacterial infections. ... [L6469,L6472,L6475,L6478,L6481,L6484,L6487,L6490,L6493] The first ciprofloxacin containing product ... Ciprofloxacin is a second generation fluoroquinolone that has spawned many derivative antibiotics. …
Matched Categories: … Metabolic Side Effects of Drugs and Substances ... MATE 1 Inhibitors ... MATE 1 Substrates …
Matched Products: … N/A ... Ciprofloxacin in Dextrose ... CIPROFLAXACINA 1 % …
Zucapsaicin, the cis-isomer of capsaicin, is a topical analgesic used to treat osteoarthritis of the knee and other neuropathic pain. It is a modulator of transient receptor potential cation channel subfamily V member 1 (TRPV-1), also known as the vanilloid or capsaicin receptor 1, that reduces pain and improves articular...
Approved
Investigational
Matched Description: … Zucapsaicin was approved by the Health Canada in 2010 as topical cream marketed under the brand name ... It is a modulator of transient receptor potential cation channel subfamily V member 1 (TRPV-1), also ... Zucapsaicin, the cis-isomer of capsaicin, is a topical analgesic used to treat osteoarthritis of the
Silicon dioxide, or silica, is an oxide of silicon with the chemical formula SiO2. It is found in nature as agate, amethyst, chalcedony, cristobalite, flint, sand, QUARTZ, and tridymite as transparent and tasteless crystals. Inhalation of fine crystals is toxic to humans leading to respiratory toxicity. In powdered food products...
Approved
Matched Description: … Silicon dioxide, or silica, is an oxide of silicon with the chemical formula SiO2. ... In powdered food products and pharmaceutical tablets, silicon dioxide is added as a flow agent to absorb ... Inhalation of fine crystals is toxic to humans leading to respiratory toxicity. …
Matched Mixtures name: … Exoden All In One ... Calcium and Magnesium 1:1 Plus Tablets ... the naked object DeBlack PackToothpaste …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Ammonia N 13 Injection, USP is a positron emitting radiopharmaceutical that is used for diagnostic purposes in conjunction with positron emission tomography (PET) imaging. The active ingredient, [13N] ammonia, has the molecular formula of 13NH3 with a molecular weight of 16.02. Ammonia N 13 Injection, USP is used for imaging...
Approved
Matched Description: … The active ingredient, [13N] ammonia, has the molecular formula of 13NH3 with a molecular weight of 16.02 ... Ammonia N 13 Injection, USP is used for imaging of the myocardium under rest or pharmacologic stress ... in conjunction with positron emission tomography (PET) imaging. …
A local anesthetic that is chemically related to bupivacaine but pharmacologically related to lidocaine. It is indicated for infiltration, nerve block, and epidural anesthesia. Mepivacaine is effective topically only in large doses and therefore should not be used by this route. (From AMA Drug Evaluations, 1994, p168)
Approved
Vet approved
Matched Synonyms: … 1-methyl-2',6'-pipecoloxylidide ... (+-)-1-Methyl-2',6'-pipecoloxylidide ... N-(2,6-Dimethylphenyl)-1-methyl-2-piperidinecarboxamide …
Matched Iupac: … N-(2,6-dimethylphenyl)-1-methylpiperidine-2-carboxamide …
Matched Description: … Mepivacaine is effective topically only in large doses and therefore should not be used by this route ... A local anesthetic that is chemically related to bupivacaine but pharmacologically related to lidocaine …
Matched Mixtures name: … 2% Polocaine Dental With Levonordefrin 1:20,000 …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Products: … A. T. O. MEPIVACAINE 3% PLAIN. SOLUCION INYECTYABLE ... Carbocaine 1% ... Carbocaine Liq 1% …
A mixture of fish oil and primrose oil, doconexent is used as a high-docosahexaenoic acid (DHA) supplement. DHA is a 22 carbon chain with 6 cis double bonds with anti-inflammatory effects. It can be biosythesized from alpha-linolenic acid or commercially manufactured from microalgae. It is an omega-3 fatty acid and...
Approved
Investigational
Matched Description: … A mixture of fish oil and primrose oil, doconexent is used as a high-docosahexaenoic acid (DHA) supplement ... It is an omega-3 fatty acid and primary structural component of the human brain, cerebral cortex, skin ... The amino-phospholipid DHA is found at a high concentration across several brain subcellular fractions …
Matched Mixtures name: … UltimateCare ONE NF ... Herbs of Gold Salmon Oil 1000 mg …
Sulfisoxazole acetyl is an ester of sulfisoxazole, a broad-spectrum sulfanilamide and a synthetic analog of para-aminobenzoic acid (PABA) with antibacterial activity. Sulfisoxazole acetyl competes with PABA for the bacterial enzyme, dihydropteroate synthase, preventing the incorporation of PABA into dihydrofolic acid, which is the precursor of folic acid. This process causes...
Approved
Vet approved
Matched Description: … and pyrimidines, resulting in cell growth arrest and cell death [L2788]. ... Sulfisoxazole acetyl is an ester of _sulfisoxazole_, a broad-spectrum sulfanilamide and a synthetic analog ... It is often combined with erythromycin to treat acute otitis media caused by the bacteria, haemophilus …
Matched Categories: … combinations of sulfonamides …
Physiologic methyl radical donor involved in enzymatic transmethylation reactions and present in all living organisms. It possesses anti-inflammatory activity and has been used in treatment of chronic liver disease. (From Merck, 11th ed)
Approved
Investigational
Nutraceutical
Matched Description: … It possesses anti-inflammatory activity and has been used in treatment of chronic liver disease. ... Physiologic methyl radical donor involved in enzymatic transmethylation reactions and present in all …
Matched Salts cas: … 200393-05-1
Human Rho(D) immune globulin is a medicine given by intramuscular or intravenous injection that is used to prevent the immunological condition known as Rh disease (or hemolytic disease of newborn). Rho (D) immune globulin is available as a sterile, lyophilized or liquid gamma globulin (IgG) fraction containing antibodies to the...
Approved
Investigational
Matched Description: … Human Rho(D) immune globulin is a medicine given by intramuscular or intravenous injection that is used ... It was approved by FDA as treatment for suppression of rhesus (Rh) isoimmunization or chronic immune ... thrombocytopenic purpura (ITP) in adults. …
Matched Products: … rhophylac 300 microgram/2ml,solution for injection in pre-filled syringe ... WIN RHO SDF 300 MCG FLAKON, 1 ADET ... IMMUNORHO 300 MCG (1500 IU)/ 2 ML IM ENJEKSIYON ICIN LIYOFILIZE TOZ ICEREN FLAKON, 1 ADET …
Glycopyrronium, also known as NVA237 or glycopyrrolate, is a racemic mixture of two enantiomers. They are both quaternary ammonium compounds and long acting muscarinic antagonists. It is one of the most commonly prescribed anticholinergic medications.[A233535,A233540] Early research into glycopyrronium use was for its indication as an adjunct therapy in the...
Approved
Investigational
Vet approved
Matched Iupac: … 3-[(2-cyclopentyl-2-hydroxy-2-phenylacetyl)oxy]-1,1-dimethylpyrrolidin-1-ium …
Matched Description: … the treatment of peptic ulcers. ... [A233570,L33090] Later research, taking advantage of the systemic distribution of muscarinic receptors ... [L33110] It is one of the most commonly prescribed anticholinergic medications. …
Matched Salts cas: … 1624259-25-1
Matched Categories: … MATE 1 Substrates ... Heterocyclic Compounds, 1-Ring …
Poa pratensis pollen is the pollen of the Poa pratensis plant. Poa pratensis pollen is mainly used in allergenic testing.
Approved
Matched Description: … Poa pratensis pollen is the pollen of the Poa pratensis plant. ... Poa pratensis pollen is mainly used in allergenic testing. …
Matched Mixtures name: … Mixture of Six Standardized Grasses ... Mixture of Four Standardized Grasses ... Mixture of Five Standardized Grasses …
Remifentanil (marketed by Abbott as Ultiva) is a potent ultra short-acting synthetic opioid given to patients during surgery for pain relief and adjunctive to an anaesthetic. Remifentanil is a specific mu-type-opioid receptor agonist which means it reduces sympathetic nervous system tone, and causes respiratory depression and analgesia.
Approved
Matched Iupac: … methyl 1-(3-methoxy-3-oxopropyl)-4-(N-phenylpropanamido)piperidine-4-carboxylate …
Matched Description: … Remifentanil (marketed by Abbott as Ultiva) is a potent ultra short-acting synthetic opioid given to ... Remifentanil is a specific mu-type-opioid receptor agonist which means it reduces sympathetic nervous …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …
Matched Products: … REMIFENTANILO 2 MG POLVO PARA RECONSTITUIR A SOLUCION INYECTABLE ... REMIFENTANILO 2MG POLVO PARA RECONSTITUIR A SOLUCION INYECTABLE O INFUSION INTRAVENOSA ... REMIFENTANILO 1 MG/ML …
Tamoxifen is a non-steroidal antiestrogen used to treat estrogen receptor positive breast cancers as well as prevent the incidence of breast cancer in high risk populations.[A1025,L7799,L7802] Tamoxifen is used alone or as an adjuvant in these treatments.[L7799,L7802] Tamoxifen may no longer be the preferred treatment for these types of cancers...
Approved
Matched Synonyms: … 1-p-beta-Dimethylaminoethoxyphenyl-trans-1,2-diphenylbut-1-ene ... 1-para-beta-Dimethylaminoethoxyphenyl-trans-1,2-diphenylbut-1-ene ... (Z)-2-(4-(1,2-Diphenyl-1-butenyl)phenoxy)-N,N-dimethylethanamine …
Matched Iupac: … (2-{4-[(1Z)-1,2-diphenylbut-1-en-1-yl]phenoxy}ethyl)dimethylamine …
Matched Description: … well as prevent the incidence of breast cancer in high risk populations. ... [L7799,L7802] Tamoxifen may no longer be the preferred treatment for these types of cancers as patients ... Tamoxifen is a non-steroidal antiestrogen used to treat estrogen receptor positive breast cancers as …
Matched Salts cas: … 54965-24-1
Matched Categories: … UGT2B7 Substrates with a Narrow Therapeutic Index ... P-glycoprotein substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP1A2 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP2A6 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP2B6 Substrates with a Narrow Therapeutic Index …
Quizartinib is an oral and potent fms-like tyrosine kinase 3 (FLT3) inhibitor and it is the first drug developed specifically targeting FLT3, as other agents with FLT3 inhibition activities were investigated with other targets in mind. Additionally, quizartinib also demonstrates inhibitory activity toward FLT3 with internal tandem duplication (ITD), although...
Approved
Investigational
Matched Iupac: … ]dodeca-1(8),3,5,9,11-pentaen-4-yl}phenyl)urea ... 3-(5-tert-butyl-1,2-oxazol-3-yl)-1-(4-{10-[2-(morpholin-4-yl)ethoxy]-7-thia-2,5-diazatricyclo[6.4.0.0²,⁶ …
Matched Description: … a maintenance monotherapy resulted in a 22% reduction in the risk of death. ... [L47426] FLT3-ITD mutation is present in 75% of FLT3-mutated AML, leading to constitutively active FLT3 ... [A260641] Quizartinib was approved by the FDA in July 2023 and developed under the brand name VANFLYTA …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Prucalopride is a dihydrobenzofurancarboxamide derivative from the benzofurane family that selectively stimulates 5-HT4 receptors and thus, it presents enterokinetic properties. The high selectivity of prucalopride allowed further development as it prevented the cardiac adverse reactions observed due to non-target effects of precedent therapies. Prucalopride was developed by Shire Development LLC...
Approved
Matched Iupac: … 4-amino-5-chloro-N-[1-(3-methoxypropyl)piperidin-4-yl]-2,3-dihydro-1-benzofuran-7-carboxamide …
Matched Description: … A40250] in Canada on December 7, 2011 and by the FDA on December 17, 2018. ... [A40254] Prucalopride was developed by Shire Development LLC and approved for use in Europe in 2009,[ ... Prucalopride is a dihydrobenzofurancarboxamide derivative from the benzofurane family that selectively …
Matched Products: … Resolor Film-coated Tablet 1 mg ... รีโซลอร์ ยาเม็ดเคลือบฟิล์ม (1 มิลลิกรัม) ... RESOLOR ® TABLETAS RECUBIERTAS DE 1 MG …
Hypromellose, or hydroxypropyl methylcellulose (HPMC) , is a semisynthetic, inert, and viscoelastic polymer that forms a colloid solution when dissolved in water. It acts as a thickening agent, coating polymer, bioadhesive, solubility enhancer in solid dispersions, and binder in the process of granulation and in modified release formulations . It...
Approved
Matched Description: … of a drug in a controlled fashion, effectively increasing the duration of release of a drug to prolong ... , and binder in the process of granulation and in modified release formulations [A24840]. ... It is a commonly used as a delivery component in oral pharmaceutical products that provides the release …
Matched Mixtures name: … Rohto All-In-One ... TEARS NATURALE II 1 MG/ML + 3 MG/ML GÖZ DAMLASI …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Products: … Alcon Tears 1% ... Sandoz Eyelube 1% ... Mc Methylcellulose Solution 1% …
Losartan is an angiotensin II receptor blocker (ARB) used to treat hypertension. Angiotensin-converting enzyme (ACE) inhibitors are used for a similar indication but are associated with a cough. When patients with ACE inhibitor associated coughs are switched to ARBs like losartan, they have an incidence of cough similar to placebo...
Approved
Matched Synonyms: … (2-butyl-4-chloro-1-{[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl}-1H-imidazol-5-yl)methanol ... 2-n-butyl-4-chloro-5-hydroxymethyl-1-[(2'-(1H-tetrazol-5-yl)biphenyl-4-yl)methyl]imidazole …
Matched Iupac: … (2-butyl-4-chloro-1-{[2'-(2H-1,2,3,4-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl]methyl}-1H-imidazol-5-yl)methanol …
Matched Description: … [L7423] Losartan is available as losartan potassium oral tablets as well as a combination tablet of losartan ... with a cough. ... patients with ACE inhibitor associated coughs are switched to ARBs like losartan, they have an incidence of
Matched Categories: … Agents Acting on the Renin-Angiotensin System ... Heterocyclic Compounds, 1-Ring ... Angiotensin II Type 1 Receptor Blockers …
Matched Products: … A-Losartan 50mg Tablets ... A-Losartan 100mg Tablets …
Dienestrol is a synthetic, non-steroidal estrogen. It is an estrogen receptor agonist. Estrogens work partly by increasing a normal clear discharge from the vagina and making the vulva and urethra healthy. Using or applying an estrogen relieves or lessens: dryness and soreness in the vagina, itching, redness, or soreness of...
Approved
Investigational
Matched Description: … Estrogens work partly by increasing a normal clear discharge from the vagina and making the vulva and ... , or soreness of the vulva. ... inflammation of the vagina (atrophic vaginitis), and inflammation of the urethra (atrophic urethritis …
Matched Categories: … Sex Hormones and Modulators of the Genital System …
Celecoxib, a selective cyclooxygenase-2 (COX-2) inhibitor, is a nonsteroidal anti-inflammatory drug (NSAID) which is known for its decreased risk of causing gastrointestinal bleeding compared to other NSAIDS. It is used to manage symptoms of various types of arthritis pain and in familial adenomatous polyposis (FAP) to reduce precancerous polyps in...
Approved
Investigational
Matched Synonyms: … p-(5-p-Tolyl-3-(trifluoromethyl)pyrazol-1-yl)benzenesulfonamide …
Matched Iupac: … 4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]benzene-1-sulfonamide …
Matched Description: … [A181532] It is marketed by Pfizer under the brand name Celebrex, and was initially granted FDA approval ... polyposis (FAP) to reduce precancerous polyps in the colon. ... clinical trials for a variety of malignancies. …
Matched Categories: … combinations of sulfonamides …
Ioxitalamate is an ionic iodinated contrast medium. It is a first-generation contrast media formed by an ionic monomer with a high osmolarity of 1500-1800 mOsm/kg. Ioxitalamic acid in the salt forms of sodium and meglumine was developed by Liebel-Flarshem Canada Inc and approved by Health Canada in 1995. Until the...
Approved
Matched Description: … [A33006] Ioxitalamic acid in the salt forms of sodium and meglumine was developed by Liebel-Flarshem ... [A27209] It is a first-generation contrast media formed by an ionic monomer with a high osmolarity of ... Until the last review in 2015, this drug is still available in the market.[L1113] …
Matched Salts cas: … 29288-99-1
Matched Categories: … Compounds used in a research, industrial, or household setting ... Diagnostic Uses of Chemicals …
Gadoxetic acid (gadoxetate) is a paramagnetic gadolinium-containing ionic linear contrast agent in which its salt form, gadoxetate disodium, is used for intravenous injection. Ethoxybenzyl diethylenetriaminepentaacetic acid is the moiety that chelates with a gadolinium ion and forms a stable complex with it to make up the drug. Gadoxetate is a...
Approved
Matched Description: … under the brand name EOVIST and FDA approved in 2008. ... liver tumor cells lack OATPs, liver tumors show a lack of contrast of enhancement and therefore heightening ... Gadoxetic acid (gadoxetate) is a paramagnetic gadolinium-containing ionic linear contrast agent in which …
Matched Categories: … Compounds used in a research, industrial, or household setting ... Diagnostic Uses of Chemicals …
Matched Products: … PRIMOVIST 0,25 MMOL/ML ENJEKSIYON ICIN COZELTI ICEREN KULLANIMA HAZIR ENJEKTOR, 1 ADET …
Phenol is an antiseptic and disinfectant. It is active against a wide range of micro-organisms including some fungi and viruses, but is only slowly effective against spores. Phenol has been used to disinfect skin and to relieve itching. Phenol is also used as an oral analgesic or anesthetic in products...
Approved
Experimental
Matched Description: … During the second world war, phenol injections were used as a means of execution by the Nazis. ... It is active against a wide range of micro-organisms including some fungi and viruses, but is only slowly ... Additionally, phenol and its related compounds are used in surgical ingrown toenail treatment, a process …
Matched Mixtures name: … Kank-A with Blistex Medicated Lip …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Products: … Pain A Lay …
An antiarrhythmia agent that is particularly effective in ventricular arrhythmias. It also has weak beta-blocking activity. The drug is generally well tolerated.
Approved
Matched Synonyms: … 1-(2-(2-hydroxy-3-(propylamino)propoxy)phenyl)-3-phenyl-1-propanone …
Matched Iupac: … 1-{2-[2-hydroxy-3-(propylamino)propoxy]phenyl}-3-phenylpropan-1-one …
Matched Description: … The drug is generally well tolerated. ... An antiarrhythmia agent that is particularly effective in ventricular arrhythmias. …
Thermomyces lanuginosus allergenic extract is used in allergenic testing.
Approved
Matched Description: … Thermomyces lanuginosus allergenic extract is used in allergenic testing. …
Fluciclovine is a [18F]-tagged synthetic analog of the amino acid L-leucine. It presents excellent diagnostic properties to be used in positron emission tomography (PET) imaging. The structure of fluciclovine allows it to be uptaken by the tumoral cells by its amino acid transporter without incorporating in the metabolism within the...
Approved
Matched Synonyms: … (1R,3R)-1-amino-3(18F)fluorocyclobutane-1-carboxylic acid ... Anti-1-amino-3-(18F)fluorocyclobutane-1-carboxylic acid …
Matched Iupac: … (1r,3r)-1-amino-3-(¹⁸F)fluorocyclobutane-1-carboxylic acid …
Matched Description: … Fluciclovine is a [18F]-tagged synthetic analog of the amino acid L-leucine. ... [A31384] The structure of fluciclovine allows it to be uptaken by the tumoral cells by its amino acid ... transporter without incorporating in the metabolism within the body. …
Displaying drugs 376 - 400 of 14564 in total