Displaying drugs 426 - 450 of 13476 in total
Tapinarof
Tapinarof is a novel, first-in-class, small-molecule AhR agonist that is indicated for the treatment of adult psoriasis. It is available as a topical cream to be applied to the affected area once daily.[L41845, A248790] Tapiranof was first discovered as a metabolite (3,5-dihydroxy-4-isopropylstilbene) produced in Photorhabdus luminescens, a gram-negative bacillus that...
Approved
Investigational
Matched Synonyms: … 3,5-Dihydroxy-4-isopropyl-trans-stilbene …
Matched Iupac: … 5-[(E)-2-phenylethenyl]-2-(propan-2-yl)benzene-1,3-diol …
Matched Description: … [L41845, A248790] Tapiranof was first discovered as a metabolite (3,5-dihydroxy-4-isopropylstilbene) ... [A248790] In 1959, it was noticed that _Heterorhabditis_ with a high amount of 3,5-dihydroxy-4-isopropylstilbene …
Matched Iupac: … 5-[(E)-2-phenylethenyl]-2-(propan-2-yl)benzene-1,3-diol …
Matched Description: … [L41845, A248790] Tapiranof was first discovered as a metabolite (3,5-dihydroxy-4-isopropylstilbene) ... [A248790] In 1959, it was noticed that _Heterorhabditis_ with a high amount of 3,5-dihydroxy-4-isopropylstilbene …
Desipramine
Desipramine hydrochloride is a dibenzazepine-derivative tricyclic antidepressant (TCA). TCAs are structurally similar to phenothiazines. They contain a tricyclic ring system with an alkyl amine substituent on the central ring. In non-depressed individuals, desipramine does not affect mood or arousal, but may cause sedation. In depressed individuals, desipramine exerts a positive...
Approved
Investigational
Matched Iupac: … (3-{2-azatricyclo[9.4.0.0^{3,8}]pentadeca-1(15),3,5,7,11,13-hexaen-2-yl}propyl)(methyl)amine …
Streptococcus pneumoniae type 4 capsular polysaccharide diphtheria CRM197 protein conjugate antigen
Streptococcus pneumoniae type 4 capsular polysaccharide diphtheria CRM197 protein conjugate antigen is a sterile vaccine that contains saccharides of the capsular antigens of Streptococcus pneumoniae serotype 4 individually conjugated to the CRM197 protein, a nontoxic variant of diphtheria toxin isolated from cultures of Corynebacterium diphtheriae strain C7 (β197). It is...
Approved
Investigational
Matched Synonyms: … Streptococcus pneumoniae serotype 4 capsular antigen diphtheria CRM197 protein conjugate vaccine …
Matched Name: … Streptococcus pneumoniae type 4 capsular polysaccharide diphtheria CRM197 protein conjugate antigen …
Matched Description: … Streptococcus pneumoniae type 4 capsular polysaccharide diphtheria CRM197 protein conjugate antigen is ... contained in the vaccine under the market name Prevnar that contains the saccharides for serotypes 4, ... sterile vaccine that contains saccharides of the capsular antigens of *Streptococcus pneumoniae* serotype 4 …
Matched Name: … Streptococcus pneumoniae type 4 capsular polysaccharide diphtheria CRM197 protein conjugate antigen …
Matched Description: … Streptococcus pneumoniae type 4 capsular polysaccharide diphtheria CRM197 protein conjugate antigen is ... contained in the vaccine under the market name Prevnar that contains the saccharides for serotypes 4, ... sterile vaccine that contains saccharides of the capsular antigens of *Streptococcus pneumoniae* serotype 4 …
Taurine
Taurine, whose chemical name is 2-aminoethanesulfonic acid, is one of the most abundant amino acids in several organs. It plays important role in essential biological processes. This conditional amino acid can be either be manufactured by the body or obtained in the diet mainly by the consumption of fish and...
Approved
Nutraceutical
Matched Iupac: … 2-aminoethane-1-sulfonic acid …
Matched Description: … Taurine, whose chemical name is 2-aminoethanesulfonic acid, is one of the most abundant amino acids in …
Matched Mixtures name: … AMINOMIX 2 NOVUM 1000 ML ... AMINOMIX 2 NOVUM 1500 ML ... AMINOMIX 2 NOVUM 2000 ML …
Matched Description: … Taurine, whose chemical name is 2-aminoethanesulfonic acid, is one of the most abundant amino acids in …
Matched Mixtures name: … AMINOMIX 2 NOVUM 1000 ML ... AMINOMIX 2 NOVUM 1500 ML ... AMINOMIX 2 NOVUM 2000 ML …
Remoxipride
Remoxipride is an atypical antipsychotic agent that is specific for dopamine D2 receptors. It gained approval in the UK in 1989 but was withdrawn in 1993 after it was found to be associated with an increased incidence of aplastic anemia.[A215422,A215512]
Approved
Withdrawn
Matched Iupac: … 3-bromo-N-{[(2S)-1-ethylpyrrolidin-2-yl]methyl}-2,6-dimethoxybenzamide …
Matched Description: … Remoxipride is an atypical antipsychotic agent that is specific for dopamine D2 receptors. …
Matched Salts cas: … 117591-79-4 …
Matched Description: … Remoxipride is an atypical antipsychotic agent that is specific for dopamine D2 receptors. …
Matched Salts cas: … 117591-79-4 …
Acer rubrum pollen
Acer rubrum pollen is the pollen of the Acer rubrum plant. Acer rubrum pollen is mainly used in allergenic testing.
Approved
Matched Mixtures name: … 2 Maple Pollen Mix ... 2 Maple Pollen Mix ... 2 Maple Pollen Mix …
Oseltamivir
Oseltamivir (marketed as the product TamifluⓇ), is an antiviral neuraminidase inhibitor used for the treatment and prophylaxis of infection with influenza viruses A (including pandemic H1N1) and B. Oseltamivir exerts its antiviral activity by inhibiting the activity of the viral neuraminidase enzyme found on the surface of the virus, which...
Approved
Matched Synonyms: … Ethyl (3R,4R,5S)-4-acetamido-5-amino-3-(1-ethylpropoxy)-1-cyclohexene-1-carboxylate ... 1-Cyclohexene-1-carboxylic acid, 4-(acetylamino)-5-amino-3-(1-ethylpropoxy)-, ethyl ester, (3R-(3alpha …
Matched Iupac: … ethyl (3R,4R,5S)-5-amino-4-acetamido-3-(pentan-3-yloxy)cyclohex-1-ene-1-carboxylate …
Matched Description: … oseltamivir in people with a higher risk of developing complications including children younger than 2 …
Matched Iupac: … ethyl (3R,4R,5S)-5-amino-4-acetamido-3-(pentan-3-yloxy)cyclohex-1-ene-1-carboxylate …
Matched Description: … oseltamivir in people with a higher risk of developing complications including children younger than 2 …
Amitriptyline
Amitriptyline is a tricyclic antidepressant that has been used to treat depression for decades. ELAVIL, a previously approved branded product of amitriptyline, was first approved by the FDA in 1961. Amitriptyline has been investigated in the treatment of pain-related conditions, attributed to its analgesic properties.
Approved
Matched Iupac: … dimethyl(3-{tricyclo[9.4.0.0^{3,8}]pentadeca-1(15),3,5,7,11,13-hexaen-2-ylidene}propyl)amine …
Matched Salts cas: … 17086-03-2 …
Matched Mixtures name: … โพลีบอน 4-10 ... PMS-levazine 4/25 Tab ... Etrafon 2 10 …
Matched Salts cas: … 17086-03-2 …
Matched Mixtures name: … โพลีบอน 4-10 ... PMS-levazine 4/25 Tab ... Etrafon 2 10 …
Technetium Tc-99m pertechnetate
Technetium Tc-99m pertechnetate is a radiopharmaceutical diagnostic agent composed of an oxoanion with the chemical formula TcO4-. Pertechnetate has a wide variety of uses within nuclear medicine as it distributes within the body to a similar extent as iodine. It also concentrates in the thyroid gland, salivary glands, gastric mucosa,...
Approved
Investigational
Matched Mixtures name: … POLGENTEC 2-120 GBQ GENERADOR DE RADIONUCLEIDOS ... GENERADOR DE SOLUCION INYECTABLE DE PERTECNETATO (99MTC) DE SODIO. 2-50GBQ …
Cilgavimab
SARS-CoV-2, the causative agent of COVID-19, enters cells via the interaction between the trimeric spike (S) glycoprotein and host cell angiotensin-converting enzyme 2 (ACE2). Blocking the interaction between the receptor-binding domain (RBD) of the S1 subunit and ACE2 inhibits viral host cell entry; animal studies indicate that antibodies capable of...
Approved
Investigational
Matched Description: … (S) glycoprotein and host cell angiotensin-converting enzyme 2 (ACE2). ... SARS-CoV-2, the causative agent of COVID-19, enters cells via the interaction between the trimeric spike ... overlap with that of [tixagevimab], the two can be administered to synergistically impair SARS-CoV-2 …
Tixagevimab
SARS-CoV-2, the causative agent of COVID-19, enters cells via the interaction between the trimeric spike (S) glycoprotein and host cell angiotensin-converting enzyme 2 (ACE2). Blocking the interaction between the receptor-binding domain (RBD) of the S1 subunit and ACE2 inhibits viral host cell entry; animal studies indicate that antibodies capable of...
Approved
Investigational
Matched Description: … (S) glycoprotein and host cell angiotensin-converting enzyme 2 (ACE2). ... SARS-CoV-2, the causative agent of COVID-19, enters cells via the interaction between the trimeric spike ... cells derived from a neutralizing antibody isolated from a patient with a natural history of SARS-CoV-2 …
Azithromycin
Azithromycin is a broad-spectrum macrolide antibiotic with a long half-life and a high degree of tissue penetration . It was initially approved by the FDA in 1991 .
It is primarily used for the treatment of respiratory, enteric and genitourinary infections and may be used instead of other macrolides for...
Approved
Matched Iupac: … (2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-11-{[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl ... ]oxy}-2-ethyl-3,4,10-trihydroxy-13-{[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy}-3,5,6,8,10,12,14 …
Matched Salts cas: … 121470-24-4 …
Matched Products: … ZARET 4% POLVO PARA RECONSTITUIR (AZITROMICINA) ... ZITROTEK FILM KAPLI TABLET, 2 ADET ... AZİTROTEK 500 MG FİLM TABLET, 2 TABLET …
Matched Salts cas: … 121470-24-4 …
Matched Products: … ZARET 4% POLVO PARA RECONSTITUIR (AZITROMICINA) ... ZITROTEK FILM KAPLI TABLET, 2 ADET ... AZİTROTEK 500 MG FİLM TABLET, 2 TABLET …
Doxercalciferol
Doxercalciferol is a synthetic vitamin D2 analog that undergoes metabolic activation in vivo to form 1α,25-dihydroxyvitamin D2 (1α,25-(OH)2D2), a naturally occurring, biologically active form of vitamin D2. Doxercalciferol is indicated for the treatment of secondary hyperparathyroidism in patients with chronic kidney disease on dialysis, as well as for the treatment...
Approved
Matched Iupac: … -4-ylidene]ethylidene}-4-methylidenecyclohexane-1,3-diol ... (1R,3S,5Z)-5-{2-[(1R,3aS,4E,7aR)-1-[(2R,3E,5R)-5,6-dimethylhept-3-en-2-yl]-7a-methyl-octahydro-1H-inden …
Matched Description: … dialysis, as well as for the treatment of secondary hyperparathyroidism in patients with Stage 3 or Stage 4 …
Matched Description: … dialysis, as well as for the treatment of secondary hyperparathyroidism in patients with Stage 3 or Stage 4 …
Sodium sulfide
Sodium sulfide is a chemical compound with a chemical formula Na2S. Sodium sulfide is used in the pulp and paper industry, water treatment, textile industry, and various chemical manufacturing processes including the production of rubber chemicals, sulfur dyes and oil recovery. Along with its hydrate form, sodium sulfide releases hydrogen...
Approved
Dimethyl sulfoxide
A highly polar organic liquid, that is used widely as a chemical solvent. Because of its ability to penetrate biological membranes, it is used as a vehicle for topical application of pharmaceuticals. It is also used to protect tissue during cryopreservation. Dimethyl sulfoxide shows a range of pharmacological activity including...
Approved
Vet approved
Matched Synonyms: … S(O)Me2 …
Rufinamide
Rufinamide is a triazole derivative and an anticonvulsant medication to treat seizure disorders like Lennox-Gastuat syndrome, a form of childhood epilepsy. Clinical trials suggest its efficacy in the treatment of partial seizures.
Approved
Matched Iupac: … 1-[(2,6-difluorophenyl)methyl]-1H-1,2,3-triazole-4-carboxamide …
Interferon alfa-n3
Purified, natural (n is for natural) human interferon alpha proteins (consists of 3 forms or polymorphisms including 2a, 2b and 2c). 166 residues, some are glycosylated (MW range from 16 kD to 27 kD).
Approved
Investigational
Iohexol
Iohexol is an effective non-ionic, water-soluble contrast agent which is used in myelography, arthrography, nephroangiography, arteriography, and other radiographic procedures. Its low systemic toxicity is the combined result of low chemotoxicity and low osmolality.
Approved
Bismuth subgallate
Bismuth subgallate is a yellow colored substance that presents as an odorless powder that undergoes discoloration when exposed to sunlight. It is a heavy metal salt of gallic acid that is highly insoluble and poorly absorbed. Possessing protective effects on the gastric mucosa, strong astringent effects, and not as yet...
Approved
Matched Iupac: … 2,7-dihydroxy-2H-benzo[d]1,3-dioxa-2-bismacyclopentane-5-carboxylic acid …
Antithrombin III human
A plasma alpha 2 glycoprotein that accounts for the major antithrombin activity of normal plasma and also inhibits several other enzymes. It is a member of the serpin superfamily.
Approved
Matched Description: … A plasma alpha 2 glycoprotein that accounts for the major antithrombin activity of normal plasma and …
Lactitol
Lactitol, also known as 4-β-D-galactopyranosyl-D-glucitol, is a sugar alcohol synthesized from lactose. It is used in food manufacturing as a nutritive sweetener and is approximately 35% as sweet as table sugar (i.e. sucrose). Clinically, lactitol has been investigated for use as an osmotic laxative and, along with other non-absorbable disaccharides...
Approved
Investigational
Matched Iupac: … (2S,3R,4R,5R)-4-{[(2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}hexane-1,2,3,5,6-pentol …
Matched Description: … Lactitol, also known as 4-β-D-galactopyranosyl-D-glucitol, is a sugar alcohol synthesized from [lactose …
Matched Description: … Lactitol, also known as 4-β-D-galactopyranosyl-D-glucitol, is a sugar alcohol synthesized from [lactose …
Artesunate
Artesunate is indicated for the initial treatment of severe malaria. The World Health Organization recommends artesunate as first line treatment for severe malaria. Artesunate was developed out of a need for a more hydrophilic derivative of artemisinin. Artesunate was granted FDA approval on 26 May 2020.
Approved
Investigational
Matched Iupac: … 4-oxo-4-{[(1R,4S,5R,8S,9R,10S,12R,13R)-1,5,9-trimethyl-11,14,15,16-tetraoxatetracyclo[10.3.1.0⁴,¹³.0⁸,¹³ …
Matched Salts cas: … 82864-68-4 …
Matched Salts cas: … 82864-68-4 …
Famtozinameran
The Omicron variant of SARS-CoV-2 is a variant of concern that was first reported in November 2021. It tends to cause less severe disease but is significantly more virulent than both the original virus and earlier variants (e.g. Delta). As of November 2022, it is the primary circulating variant of...
Approved
Investigational
Matched Description: … [L43917]
Famtozinameran is an mRNA vaccine encoding the S glycoprotein of SARS-CoV-2 Omicron variant ... lineages BA.4 and BA.5. ... including infection caused by Omicron BA.4/BA.5. …
Matched Mixtures name: … Comirnaty Original & Omicron Ba.4/ba.5 ... Comirnaty Original & Omicron Ba.4/ba.5 ... Comirnaty Original & Omicron Ba.4/ba.5 …
Matched Mixtures name: … Comirnaty Original & Omicron Ba.4/ba.5 ... Comirnaty Original & Omicron Ba.4/ba.5 ... Comirnaty Original & Omicron Ba.4/ba.5 …
Acer saccharum pollen
Acer saccharum pollen is the pollen of the Acer saccharum plant. Acer saccharum pollen is mainly used in allergenic testing.
Approved
Matched Mixtures name: … 2 Maple Pollen Mix ... 2 Maple Pollen Mix ... 2 Maple Pollen Mix …
Diiodohydroxyquinoline
Diiodohydroxyquinoline, also known as uidoquinol and iodoquinol, is a quinoline derivative that can be used in the treatment of amoebiasis. The exact mechanism of action is unknown. Iodoquinol is not currently available in any FDA-approved products.
Approved
Matched Mixtures name: … Hydrocortisone 2.5% / Iodoquinol 1% / Ketoconazole 2% ... Iodoquinol 1% - Hydrocortisone Acetate 2% - Aloe Polysaccharides 1% …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Displaying drugs 426 - 450 of 13476 in total