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Displaying drugs 451 - 475 of 6316 in total
Recombinant human coagulation Factor VIIa (rFVIIa), intended for promoting hemostasis by activating the extrinsic pathway of the coagulation cascade. NovoSeven is a vitamin K-dependent glycoprotein consisting of 406 amino acid residues. Cloned and expressed in hamster kidney cells, the protein is catalytically active in a two-chain form.
Approved
Matched Description: … NovoSeven is a vitamin K-dependent glycoprotein consisting of 406 amino acid residues. ... Cloned and expressed in hamster kidney cells, the protein is catalytically active in a two-chain form …
Matched Products: … NOVOSEVEN RT 1 MG ... NOVOSEVEN® RT 2 MG ... NOVOSEVEN RT 1 MG (50 KIU) ENJEKSİYONLUK ÇÖZELTİ İÇİN TOZ VE ÇÖZÜCÜ …
Naproxen is classified as a nonsteroidal anti-inflammatory dug (NSAID) and was initially approved for prescription use in 1976 and then for over-the-counter (OTC) use in 1994. It can effectively manage acute pain as well as pain related to rheumatic diseases, and has a well studied adverse effect profile. Given its...
Approved
Vet approved
Matched International brands: … Bumaflex N
Matched Synonyms: … (+)-2-(6-Methoxy-2-naphthyl)propionic acid ... (+)-2-(Methoxy-2-naphthyl)-propionsäure ... (+)-2-(Methoxy-2-naphthyl)-propionic acid …
Matched Iupac: … (2S)-2-(6-methoxynaphthalen-2-yl)propanoic acid …
Matched Description: … for a variety of clinical situations requiring analgesia. ... Naproxen is classified as a nonsteroidal anti-inflammatory dug (NSAID) and was initially approved for ... A178975] It can effectively manage acute pain as well as pain related to rheumatic diseases, and has a
Matched Salts cas: … 26159-34-2
Matched Categories: … Non COX-2 selective NSAIDS …
Matched Products: … NAPROXENO 3 % ... NAPROXENO SUSPENSION 3% ... A-NOX FORT 550 MG TABLET, 20 ADET …
Tixocortol is a 21-thiol derivative of hydrocortisone classified as a class A corticosteroid. It is a synthetic steroid with topical anti-inflammatory properties without the systemic glucocorticoid and mineralocorticoid activities and toxicity.
Approved
Withdrawn
Matched Iupac: … (1S,2R,10S,11S,14R,15S,17S)-14,17-dihydroxy-2,15-dimethyl-14-(2-sulfanylacetyl)tetracyclo[8.7.0.0²,⁷.0¹¹,¹⁵ …
Matched Description: … Tixocortol is a 21-thiol derivative of hydrocortisone classified as a class A corticosteroid. ... It is a synthetic steroid with topical anti-inflammatory properties without the systemic glucocorticoid …
Matched Categories: … 11-Hydroxycorticosteroids …
Berotralstat is a selective inhibitor of plasma kallikrein used in the prophylaxis of attacks of hereditary angioedema (HAE). It works by blocking the enzymatic activity of plasma kallikrein in releasing bradykinin, the major biologic peptide that promotes swelling and pain associated with attacks of HAE. Berotralstat is strictly used to...
Approved
Matched Synonyms: … (+)-1-(3-(aminomethyl) phenyl)-N-(5-((3-cyanophenyl)(cyclopropylmethylamino)methyl)-2-fluorophenyl)-3 ... (R)-1-(3-(aminomethyl) phenyl)-N-(5-((3- cyanophenyl)(cyclopropylmethylamino)methyl)-2-fluorophenyl)- ... 2-[3-(aminomethyl)phenyl]-N-[5-[(R)-(3-cyanophenyl)-(cyclopropylmethylamino)methyl]-2-fluorophenyl]-5 …
Matched Iupac: … 1-[3-(aminomethyl)phenyl]-N-{5-[(R)-(3-cyanophenyl)[(cyclopropylmethyl)amino]methyl]-2-fluorophenyl}- ... 3-(trifluoromethyl)-1H-pyrazole-5-carboxamide …
Matched Description: … Berotralstat is a selective inhibitor of plasma kallikrein used in the prophylaxis of attacks of hereditary ... [A225106] Berotralstat was first approved by the FDA on December 3, 2020, as the first once-daily oral …
Matched Salts cas: … 1809010-52-3
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Tetracycline is a broad spectrum polyketide antibiotic produced by the Streptomyces genus of Actinobacteria. It exerts a bacteriostatic effect on bacteria by binding reversible to the bacterial 30S ribosomal subunit and blocking incoming aminoacyl tRNA from binding to the ribosome acceptor site. It also binds to some extent to the...
Approved
Vet approved
Withdrawn
Matched Synonyms: … 12aS)-4-(Dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-2- …
Matched Iupac: … dimethylamino)-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2- …
Matched Description: … Tetracycline is a broad spectrum polyketide antibiotic produced by the Streptomyces genus of Actinobacteria ... It exerts a bacteriostatic effect on bacteria by binding reversible to the bacterial 30S ribosomal subunit ... for the use of all liquid oral drug products formulated for pediatric use containing tetracycline in a
Matched Products: … Tetracycline 3 percent a First Aid Antibiotic ... Achromycin Ont Oph 1% ... Tetracycline 1% Ophthalmic Ointment …
Becaplermin is produced by recombinant DNA technology by insertion of the gene for the B chain of platelet derived growth factor (PDGF) into the yeast, Saccharomyces cerevisiae. Becaplermin has a molecular weight of approximately 25 KD and is a homodimer composed of two identical polypeptide chains that are bound together...
Approved
Investigational
Matched Synonyms: … PDGF-2
Matched Description: … Becaplermin has a molecular weight of approximately 25 KD and is a homodimer composed of two identical ... Becaplermin is produced by recombinant DNA technology by insertion of the gene for the B chain of platelet …
Unfractionated heparin (UH) is a heterogenous preparation of anionic, sulfated glycosaminoglycan polymers with weights ranging from 3000 to 30,000 Da. It is a naturally occurring anticoagulant released from mast cells. It binds reversibly to antithrombin III (ATIII) and greatly accelerates the rate at which ATIII inactivates coagulation enzymes thrombin (factor...
Approved
Investigational
Matched Description: … It is a naturally occurring anticoagulant released from mast cells. ... Unfractionated heparin (UH) is a heterogenous preparation of anionic, sulfated glycosaminoglycan polymers ... infusions; activated partial prothrombin time (aPTT) monitoring is required when using UH; and UH has a
Matched Mixtures name: … BARICUS 50 IU/%1/%10 JEL , 50 G …
Matched Products: … THROMBOCUTAN 30000IE GEL N ... THROMBOCUTAN 30000IE SAL N ... B. BRAUN HEPARINISED SALINE 10IU/ML SOLUTION FOR INJECTION …
A glucocorticoid employed, usually as eye drops, in the treatment of allergic and inflammatory conditions of the eye. It has also been used topically in the treatment of various skin disorders. (From Martindale, The Extra Pharmacopoeia, 30th ed, p732)
Approved
Investigational
Matched Synonyms: … (1R,2S,8S,10S,11S,14R,15S,17S)-14-acetyl-1-fluoro-14,17-dihydroxy-2,8,15-trimethyltetracyclo[8.7.0.02,7.011,15 …
Matched Iupac: … ,4H,5H,7H,9aH,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-7-one ... (1R,3aS,3bS,5S,9aS,9bR,10S,11aS)-1-acetyl-9b-fluoro-1,10-dihydroxy-5,9a,11a-trimethyl-1H,2H,3H,3aH,3bH …
Matched Description: … A glucocorticoid employed, usually as eye drops, in the treatment of allergic and inflammatory conditions …
Pantethine is a naturally occurring compound synthesized in the body from pantothenic acid (vitamin B5) via addition of cysteamine. It consists of two molecules of pantetheine that form a dimer via disufide linkages, and acts as an intermediate in the production of Coenzyme A. Coenzyme A plays an essential role...
Approved
Investigational
Matched Synonyms: … D-Bis(N-pantothenyl-beta-aminoethyl) disulfide …
Matched Iupac: … (2R)-N-[2-({2-[(2-{3-[(2R)-2,4-dihydroxy-3,3-dimethylbutanamido]propanamido}ethyl)disulfanyl]ethyl}carbamoyl …
Matched Description: … in the production of Coenzyme A. ... Coenzyme A plays an essential role as a cofactor in the metabolism of lipids and carbohydrates including ... Pantethine is a naturally occurring compound synthesized in the body from pantothenic acid (vitamin B5 …
Matched Categories: … Vitamin B Complex …
A benzimidazole broad-spectrum anthelmintic structurally related to mebendazole that is effective against many diseases. (From Martindale, The Extra Pharmacopoeia, 30th ed, p38)
Approved
Vet approved
Matched International brands: … Ben-A
Matched Synonyms: … O-methyl N-(5-(propylthio)-2-benzimidazolyl)carbamate ... 5-(propylthio)-2-carbomethoxyaminobenzimidazole ... (5-(propylthio)-1H-benzimidazol-2-yl)carbamic acid methyl ester …
Matched Iupac: … methyl N-[6-(propylsulfanyl)-1H-1,3-benzodiazol-2-yl]carbamate …
Matched Description: … A benzimidazole broad-spectrum anthelmintic structurally related to mebendazole that is effective against …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Products: … A-zole Suspension (Strawberry) 200mg/5ml ... ANDAZOL 400 MG FILM KAPLI TABLET, 1 ADET ... HELMADOL 400 MG FİLM KAPLI TABLET, 3 ADET …
Baricitinib is a Janus kinase (JAK) inhibitor. JAKs are tyrosine protein kinases that play an important role in pro-inflammatory signaling pathways. Overactive JAKs have been implicated in autoimmune disorders, such as rheumatoid arthritis. By inhibiting the actions of JAK1 and JAK2, baricitinib attenuates JAK-mediated inflammation and immune responses. Baricitinib was...
Approved
Investigational
Matched Iupac: … 2-[1-(ethanesulfonyl)-3-(4-{7H-pyrrolo[2,3-d]pyrimidin-4-yl}-1H-pyrazol-1-yl)azetidin-3-yl]acetonitrile …
Matched Description: … Baricitinib is a Janus kinase (JAK) inhibitor. ... for the treatment of rheumatoid arthritis in adults [A248395] and was later approved by the FDA in 2018 ... [A248405] While baricitinib was granted emergency use as a treatment for COVID-19 in combination with …
Matched Categories: … MATE 2 Substrates with a Narrow Therapeutic Index ... Heterocyclic Compounds, 1-Ring ... MATE 2 Inhibitors ... MATE 2 Substrates ... Heterocyclic Compounds, 2-Ring …
Matched Products: … โอลูเมียนท์ (2 มก.) ... UNAMİTY 2 MG FİLM KAPLI TABLET, 7 ADET ... UNAMİTY 2 MG FİLM KAPLI TABLET, 28 ADET …
Trypan blue is a diazo dye used in ophthalmic cataract surgery to stain the anterior capsule in the presence of a mature cataract. This is done to aid in visualization before creating the continuous curvilinear capsulorhexis.
Approved
Matched Iupac: … 5-amino-3-[(E)-2-{4'-[(E)-2-(8-amino-1-hydroxy-3,6-disulfonaphthalen-2-yl)diazen-1-yl]-3,3'-dimethyl- ... [1,1'-biphenyl]-4-yl}diazen-1-yl]-4-hydroxynaphthalene-2,7-disulfonic acid …
Matched Description: … of a mature cataract. ... Trypan blue is a diazo dye used in ophthalmic cataract surgery to stain the anterior capsule in the presence …
Matched Salts cas: … 72-57-1
Matched Categories: … Compounds used in a research, industrial, or household setting …
Ibrutinib is a small molecule that acts as an irreversible potent inhibitor of Burton's tyrosine kinase. It is designated as a targeted covalent drug and presented as a promising activity in B-cell malignancies in clinical trials. Ibrutinib was developed by Pharmacyclics Inc and was first approved by the FDA in...
Approved
Matched Synonyms: … 1-[(3R)-3-[4-Amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]piperidin-1-yl]prop-2-en-1-one …
Matched Iupac: … 1-[(3R)-3-[4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]piperidin-1-yl]prop-2-en-1-one …
Matched Description: … It is designated as a targeted covalent drug and presented as a promising activity in B-cell malignancies ... Ibrutinib is a small molecule that acts as an irreversible potent inhibitor of Burton's tyrosine kinase …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Heterocyclic Compounds, 2-Ring …
A clear, colorless liquid rapidly absorbed from the gastrointestinal tract and distributed throughout the body. It has bactericidal activity and is used often as a topical disinfectant. It is widely used as a solvent and preservative in pharmaceutical preparations as well as serving as the primary ingredient in alcoholic beverages.
Approved
Matched Synonyms: … 1-Hydroxyethane …
Matched Description: … It has bactericidal activity and is used often as a topical disinfectant. ... A clear, colorless liquid rapidly absorbed from the gastrointestinal tract and distributed throughout ... It is widely used as a solvent and preservative in pharmaceutical preparations as well as serving as …
Matched Mixtures name: … Adventure Medical Kits 1-2 Person First Aid ... Adventure Medical Kits 1-2 Person National Ski Patrol First Aid ... Dr.Mollis Anti-Virus Wet Wipes …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Products: … Orchid By H E B Vanilla Brown Sugar ... Orchid By H E B Jasmine Tea and Basil ... Aloe Scent A B Hand Sanitizing …
Miglustat, commonly marketed under the trade name Zavesca, is a drug used to treat Gaucher disease. It inhibits the enzyme glucosylceramide synthase, an essential enzyme for the synthesis of most glycosphingolipids. It is only used for patients who cannot be treated with enzyme replacement therapy with imiglucerase. Miglustat is now...
Approved
Matched Synonyms: … N-butyl-1-deoxynojirimycin ... N-(n-Butyl)deoxynojirimycin ... N-Butylmoranoline …
Matched Iupac: … (2R,3R,4R,5S)-1-butyl-2-(hydroxymethyl)piperidine-3,4,5-triol …
Matched Description: … Miglustat, commonly marketed under the trade name Zavesca, is a drug used to treat Gaucher disease. ... with miglustat showed that therapeutic levels of the drug could not be achieved in patients without a
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Human varicella-zoster immune globulin is a solvent/detergent-treated sterile liquid preparation of purified human immune globulin G (IgG) containing antibodies to varicella zoster virus (anti-VZV). It is prepared from pools of healthy human donors' plasma via anion-exchange column chromatography and was approved in 2012 under the name VariZIG to reduce the...
Approved
Matched Synonyms: … Human herpesvirus 3 immune globulin …
Matched Description: … Human varicella-zoster immune globulin is a solvent/detergent-treated sterile liquid preparation of purified ... human immune globulin G (IgG) containing antibodies to varicella zoster virus (anti-VZV). ... The therapeutic efficacy is proven if administered within 4 days of exposure to varicella zoster virus
Propiolactone is a lactone compound with a four-membered ring. It is a colorless liquid with a pungent slightly sweet odor. Propiolactone is a disinfectant used for the sterilization of blood plasma, vaccines, tissue grafts, surgical instruments, and enzymes. It has been used against bacteria, fungi, and virus. It is currently...
Approved
Withdrawn
Matched Synonyms: … 3-propanolide …
Matched Iupac: … oxetan-2-one …
Matched Description: … It has been used against bacteria, fungi, and virus. ... Propiolactone is a lactone compound with a four-membered ring. ... It is a colorless liquid with a pungent slightly sweet odor. …
Matched Categories: … Compounds used in a research, industrial, or household setting …
There is a great deal of evidence indicating that vascular endothelial growth factor (VEGF) is important for the survival and proliferation of cancer cells.[A192939,A192837,A192891,A193275] VEGF plays an important role in angiogenesis, lymphangiogenesis, and tumor growth, which are all factors that contribute to its attractiveness as a therapeutic target for anti-cancer...
Approved
Investigational
Matched Description: … neutralizing VEGF-A. ... There is a great deal of evidence indicating that vascular endothelial growth factor (VEGF) is important ... lymphangiogenesis, and tumor growth, which are all factors that contribute to its attractiveness as a
Matched Products: … ZİRABEV 100 MG/4 ML İNFÜZYONLUK ÇÖZELTİ, 1 ADET ... ZİRABEV 400 MG/16 ML İNFÜZYONLUK ÇÖZELTİ, 1 ADET ... ALTUZAN 100MG/4ML KONSANTRE INFÜZYON COZELTİSİ, 1 ADET …
Antilipemic agent that lowers cholesterol and triglycerides. It decreases low density lipoproteins and increases high density lipoproteins.
Approved
Investigational
Matched Synonyms: … 2-(p-(2-(p-Chlorobenzamido)ethyl)phenoxy)-2-methylpropionic acid …
Matched Iupac: … 2-(4-{2-[(4-chlorophenyl)formamido]ethyl}phenoxy)-2-methylpropanoic acid …
Bilastine is a novel new-generation antihistamine that is highly selective for the H1 histamine receptor, has a rapid onset and prolonged duration of action.
Approved
Investigational
Matched Iupac: … 2-[4-(2-{4-[1-(2-ethoxyethyl)-1H-1,3-benzodiazol-2-yl]piperidin-1-yl}ethyl)phenyl]-2-methylpropanoic …
Matched Description: … , has a rapid onset and prolonged duration of action. ... Bilastine is a novel new-generation antihistamine that is highly selective for the H1 histamine receptor …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Heterocyclic Compounds, 2-Ring …
Approved
Experimental
Matched Mixtures name: … Le 100 B
Remimazolam is an ultra short-acting benzodiazepine used in the induction and maintenance of sedation during short (<30 minute) procedures. Recent trends in anesthesia-related drug development have touted the benefits of so-called "soft drugs" - these agents, such as remifentanil, are designed to be metabolically fragile and thus susceptible to rapid...
Approved
Investigational
Matched Iupac: … methyl 3-[(7S)-12-bromo-3-methyl-9-(pyridin-2-yl)-2,5,8-triazatricyclo[8.4.0.0^{2,6}]tetradeca-1(14), …
Matched Description: … [A214857] These "soft drugs" are useful in the context of surgical procedures, wherein a rapid onset/ …
Matched Salts cas: … 1001415-66-2
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Zoledronic acid, or CGP 42'446, is a third generation, nitrogen containing bisphosphonate similar to ibandronic acid, minodronic acid, and risedronic acid. Zoledronic acid is used to treat and prevent multiple forms of osteoporosis, hypercalcemia of malignancy, multiple myeloma, bone metastases from solid tumors, and Paget’s disease of bone.[L13712,L13715,L13721] Zoledronic acid...
Approved
Matched Synonyms: … (1-hydroxy-2-imidazol-1-ylethylidene)diphosphonic acid ... (1-hydroxy-2-(1H-imidazol-1-yl)ethylidene)bisphosphonic acid …
Matched Iupac: … [1-hydroxy-2-(1H-imidazol-1-yl)-1-phosphonoethyl]phosphonic acid …
Matched Description: … Zoledronic acid, or CGP 42'446,[A203120] is a third generation, nitrogen containing bisphosphonate similar …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Products: … N/A ... ICIN KON.COZELTI ICEREN KUL.HAZIR SIRINGA, 3 ADET ... Zoledronic Acid - A
Intravenous immunoglobulin (IVIg) is a mixture of IgG1 and other antibodies derived from healthy human plasma via Cohn fractionation. The purification process includes cold alcohol fractionation, polyethylene glycol precipitation, and ion exchange chromatography. IVIg contains the same distribution of IgG antibody subclasses as is found in the general human population....
Approved
Investigational
Matched Description: … Intravenous immunoglobulin (IVIg) is a mixture of IgG1 and other antibodies derived from healthy human …
Matched Categories: … Antigen Neutralization …
Matched Products: … BERIGLOBINA P X 2 ML INYECTABLE ... Gamimune N 5% (iv) ... Gamimune N 10% (iv) …
Multiple Sclerosis (MS) is a chronic and inflammatory autoimmune disease of the central nervous system, disrupting communication between the brain and other parts of the body. Most patients diagnosed with this illness experience their initial disease symptoms between the age of 20 to 40, often the most productive years of...
Approved
Matched Description: … Multiple Sclerosis (MS) is a chronic and inflammatory autoimmune disease of the central nervous system …
Matched Mixtures name: … ADET 63 MGC/0.5 ML+1 ADET 94 MCG/0.5 ML ... ADET 63 MGC/0.5 ML+1 ADET 94 MCG/0.5 ML ... 0.5 ML+94 MCG/0.5 ML SC ENJEKSİYONLUK ÇÖZELTİ İÇEREN KULLANIMA HAZIR KALEM TEDAVİYE BAŞLAMA PAKETİ , 1
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Products: … PLEGRİDY 125 MCG/0.5 ML SC ENJEKSİYONLUK ÇÖZELTİ İÇEREN KULLANIMA HAZIR KALEM, 2 ADET …
Displaying drugs 451 - 475 of 6316 in total