Displaying drugs 476 - 500 of 12845 in total
Cetalkonium
Cetalkonium is a C16 alkyl benzalkonium chloride derivative with an amphipathic property which allows it to be used in different types of formulations. It is a quaternary ammonium salt that acts as an antiseptic against a variety of bacteria and fungi. Cetalkonium is approved by the FDA for its use...
Approved
Gadobutrol
Gadobutrol is a second-generation extracellular non-ionic macrocyclic GBCA (gadolinium-based contrast agent) used in magnetic resonance imaging (MRI) in adults and children older than 2 years of age. Due to its physicochemical properties, gadobutrol is
formulated at twice the gadolinium ion concentration compared to other GBCA and thus requires a lesser...
Approved
Matched Iupac: … 4,7,10-tris(carboxymethyl)-1-[(2S,3R)-1,3,4-trihydroxybutan-2-yl]-1,4,7,10-tetraaza-13-gadolinatetracyclo …
Azithromycin
Azithromycin is a broad-spectrum macrolide antibiotic with a long half-life and a high degree of tissue penetration . It was initially approved by the FDA in 1991 .
It is primarily used for the treatment of respiratory, enteric and genitourinary infections and may be used instead of other macrolides for...
Approved
Matched Iupac: … ,6S)-5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy}-3,5,6,8,10,12,14-heptamethyl-1-oxa-6-azacyclopentadecan ... ,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy}-2-ethyl-3,4,10-trihydroxy-13-{[(2R,4R,5S …
Matched Products: … ZIROMIN 500 MG IV LIYOFILIZE ENJEKSIYONLUK TOZ IÇEREN FLAKON, 1 FLAKON + 1 ÇÖZÜCÜ AMPUL ... ENJEKSİYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN LİYOFİLİZE TOZ, 1 ADET ... ZIROMIN 500 MG IV LIYOFILIZE ENJEKSIYONLUK TOZ IÇEREN FLAKON,1 ADET …
Matched Products: … ZIROMIN 500 MG IV LIYOFILIZE ENJEKSIYONLUK TOZ IÇEREN FLAKON, 1 FLAKON + 1 ÇÖZÜCÜ AMPUL ... ENJEKSİYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN LİYOFİLİZE TOZ, 1 ADET ... ZIROMIN 500 MG IV LIYOFILIZE ENJEKSIYONLUK TOZ IÇEREN FLAKON,1 ADET …
Curcumin
Curcumin, also known as diferuloylmethane, is an active component in the golden spice turmeric (Curcuma longa) and in Curcuma xanthorrhiza oil. It is a highly pleiotropic molecule that exhibits antibacterial, anti-inflammatory, hypoglycemic, antioxidant, wound-healing, and antimicrobial activities . Due to these properties, curcumin has been investigated for the treatment and...
Approved
Investigational
Selenious acid
Selenious acid is the acid form of sodium selenite, a form of selenium .
Selenium is an essential trace element and antioxidant. It is a cofactor metabolic enzyme regulation. It also plays an important role in maintaining the general health of tissue and muscle and has antioxidant properties. Selenium is...
Approved
Investigational
Matched Salts cas: … 26970-82-1 …
Matched Mixtures name: … Vege 1 Daily Tab ... Multitrace-5 ... Multitrace-5 …
Matched Mixtures name: … Vege 1 Daily Tab ... Multitrace-5 ... Multitrace-5 …
Cefixime
Bacteria possess a cell wall comprising a glycopeptide polymer commonly known as peptidoglycan, which is synthesized and remodelled through the action of a family of enzymes known as "penicillin-binding proteins" (PBPs). β-lactam antibiotics, including cephalosporins, are PBP inhibitors that, through inhibition of essential PBPs, result in impaired cell wall homeostasis,...
Approved
Investigational
Matched Iupac: … -1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid ... (6R,7R)-7-[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-[(carboxymethoxy)imino]acetamido]-3-ethenyl-8-oxo-5-thia …
Matched Mixtures name: … MOLCEF PLUS 100/62.5/5 ML ORAL SUSPANSIYON HAZIRLAMAK ICIN KURU TOZ, 100 ML ... MOLCEF PLUS 200 MG+62.5/5 ML ORAL SÜSPANSİYON HAZIRLAMAK İÇİN KURU TOZ, 100 ML …
Matched Products: … CEFIXIM AL 100 MG/5 ML PSE ... Zifi Dry Syrup 100 mg/5 ml ... Tricef 100 mg/5 ml - Trockensaft …
Matched Mixtures name: … MOLCEF PLUS 100/62.5/5 ML ORAL SUSPANSIYON HAZIRLAMAK ICIN KURU TOZ, 100 ML ... MOLCEF PLUS 200 MG+62.5/5 ML ORAL SÜSPANSİYON HAZIRLAMAK İÇİN KURU TOZ, 100 ML …
Matched Products: … CEFIXIM AL 100 MG/5 ML PSE ... Zifi Dry Syrup 100 mg/5 ml ... Tricef 100 mg/5 ml - Trockensaft …
Burosumab
Burosumab (KRN23) is an entirely human monoclonal IgG1 antibody that binds excess fibroblast growth factor 23 (FGF23) and has been successfully tested in clinical trials in children with X-linked hypophosphatemic rickets .
The U.S. Food and Drug Administration approved Crysvita (burosumab) in April 2018. This is the first drug approved...
Approved
Investigational
Matched Description: … This is the first drug approved to treat adults and children ages 1 year and older with X-linked hypophosphatemia …
Drostanolone propionate
Approved
Illicit
Matched Iupac: … (1S,3aS,3bR,5aS,8R,9aS,9bS,11aS)-8,9a,11a-trimethyl-7-oxo-hexadecahydro-1H-cyclopenta[a]phenanthren-1- …
Desipramine
Desipramine hydrochloride is a dibenzazepine-derivative tricyclic antidepressant (TCA). TCAs are structurally similar to phenothiazines. They contain a tricyclic ring system with an alkyl amine substituent on the central ring. In non-depressed individuals, desipramine does not affect mood or arousal, but may cause sedation. In depressed individuals, desipramine exerts a positive...
Approved
Investigational
Matched Synonyms: … 5-(γ-methylaminopropyl)iminodibenzyl ... 5-(gamma-methylaminopropyl)iminodibenzyl …
Matched Iupac: … (3-{2-azatricyclo[9.4.0.0^{3,8}]pentadeca-1(15),3,5,7,11,13-hexaen-2-yl}propyl)(methyl)amine …
Matched Description: … TCAs also block histamine-H1 receptors, α1-adrenergic receptors and muscarinic …
Matched Categories: … Serotonin 5-HT2 Receptor Antagonists ... Serotonin 5-HT2A Receptor Antagonists …
Matched Iupac: … (3-{2-azatricyclo[9.4.0.0^{3,8}]pentadeca-1(15),3,5,7,11,13-hexaen-2-yl}propyl)(methyl)amine …
Matched Description: … TCAs also block histamine-H1 receptors, α1-adrenergic receptors and muscarinic …
Matched Categories: … Serotonin 5-HT2 Receptor Antagonists ... Serotonin 5-HT2A Receptor Antagonists …
Dapsone
A sulfone active against a wide range of bacteria but mainly employed for its actions against mycobacterium leprae. Its mechanism of action is probably similar to that of the sulfonamides which involves inhibition of folic acid synthesis in susceptible organisms. It is also used with pyrimethamine in the treatment of...
Approved
Investigational
Matched Mixtures name: … Dapsone 6% / Niacinamide 2% / Spironolactone 5% ... Dapsone 8.5% / Niacinamide 2% / Spironolactone 5% ... 011503 Dapsone 6% / Niacinamide 2% / Spironolactone 5% …
Matched Products: … DAPTOMIX® 5% GEL ... ACNEWELL %5 JEL, 30 GRAM …
Matched Products: … DAPTOMIX® 5% GEL ... ACNEWELL %5 JEL, 30 GRAM …
Diflunisal
Diflunisal, a salicylate derivative, is a nonsteroidal anti-inflammatory agent (NSAIA) with pharmacologic actions similar to other prototypical NSAIAs. Diflunisal possesses anti-inflammatory, analgesic and antipyretic activity. Though its mechanism of action has not been clearly established, most of its actions appear to be associated with inhibition of prostaglandin synthesis via the...
Approved
Investigational
Matched Synonyms: … 5-(2,4-difluorophenyl)salicylic acid ... 2-(hydroxy)-5-(2,4-difluorophenyl)benzoic acid …
Lopinavir
Lopinavir is an antiretroviral protease inhibitor used in combination with other antiretrovirals in the treatment of HIV-1 infection. Lopinavir is marketed and administered exclusively in combination with ritonavir - this combination, first marketed by Abbott under the brand name Kaletra in 2000, is necessary due to lopinavir's poor oral bioavailability...
Approved
Matched Iupac: … (2S)-N-[(2S,4S,5S)-5-[2-(2,6-dimethylphenoxy)acetamido]-4-hydroxy-1,6-diphenylhexan-2-yl]-3-methyl-2- ... (2-oxo-1,3-diazinan-1-yl)butanamide …
Matched Description: … antiretroviral protease inhibitor used in combination with other antiretrovirals in the treatment of HIV-1 ... protease enzyme but which itself cannot be cleaved, thus preventing the activity of the HIV-1 protease ... it contains a hydroxyethylene scaffold that mimics the peptide linkage typically targeted by the HIV-1 …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Description: … antiretroviral protease inhibitor used in combination with other antiretrovirals in the treatment of HIV-1 ... protease enzyme but which itself cannot be cleaved, thus preventing the activity of the HIV-1 protease ... it contains a hydroxyethylene scaffold that mimics the peptide linkage typically targeted by the HIV-1 …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Elbasvir
Elbasvir is a direct-acting antiviral medication used as part of combination therapy to treat chronic hepatitis C, an infectious liver disease caused by infection with hepatitis C virus (HCV). HCV is a single-stranded RNA virus that is categorized into nine distinct genotypes, with genotype 1 being the most common in...
Approved
Matched Iupac: … methyl N-[(2S)-1-[(2S)-2-{5-[(9S)-14-{2-[(2S)-1-[(2S)-2-[(methoxycarbonyl)amino]-3-methylbutanoyl]pyrrolidin ... ,3,5,11(16),12,14-heptaen-5-yl]-1H-imidazol-2-yl}pyrrolidin-1-yl]-3-methyl-1-oxobutan-2-yl]carbamate ... -2-yl]-1H-imidazol-5-yl}-9-phenyl-8-oxa-10-azatetracyclo[8.7.0.0^{2,7}.0^{11,16}]heptadeca-1(17),2(7) …
Matched Description: … HCV is a single-stranded RNA virus that is categorized into nine distinct genotypes, with genotype 1 ... Approved in January 2016 by the FDA, Zepatier is indicated for the treatment of HCV genotypes 1 and 4 ... sustained virologic response (SVR), and have been shown to achieve a SVR between 94% and 97% for genotype 1 …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Description: … HCV is a single-stranded RNA virus that is categorized into nine distinct genotypes, with genotype 1 ... Approved in January 2016 by the FDA, Zepatier is indicated for the treatment of HCV genotypes 1 and 4 ... sustained virologic response (SVR), and have been shown to achieve a SVR between 94% and 97% for genotype 1 …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Daprodustat
Daprodustat is a small-molecule hypoxia-inducible factor (HIF) prolyl hydroxylase (PHD) inhibitor that was developed by GSK.[A254167,A254162] Patients with CKD cannot induce erythropoietin (EPO) production in response to hypoxia or anemia. As a potent inhibitor of PHD1, PHD2 and PHD3 (≥ 1000-fold selectivity), daprodustat stabilizes cellular HIF1α and HIF2α and the induces...
Approved
Investigational
Matched Synonyms: … Glycine, N-((1,3-dicyclohexylhexahydro-2,4,6-trioxo-5-pyrimidinyl)carbonyl)- …
Matched Iupac: … 2-[(1,3-dicyclohexyl-2,4,6-trioxo-1,3-diazinan-5-yl)formamido]acetic acid …
Matched Description: … [L43857] On February 1, 2023, daprodustat was fully approved by the FDA as the first oral treatment for …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Iupac: … 2-[(1,3-dicyclohexyl-2,4,6-trioxo-1,3-diazinan-5-yl)formamido]acetic acid …
Matched Description: … [L43857] On February 1, 2023, daprodustat was fully approved by the FDA as the first oral treatment for …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Quinine
An alkaloid derived from the bark of the cinchona tree. It is used as an antimalarial drug, and is the active ingredient in extracts of the cinchona that have been used for that purpose since before 1633. Quinine is also a mild antipyretic and analgesic and has been used in...
Approved
Matched Iupac: … (R)-[(1S,2S,4S,5R)-5-ethenyl-1-azabicyclo[2.2.2]octan-2-yl](6-methoxyquinolin-4-yl)methanol …
Matched Mixtures name: … IRUDERM 1 …
Matched Mixtures name: … IRUDERM 1 …
Anthrax vaccine
Anthrax vaccine is a vaccine used for the pre- or post-exposure prophylaxis of disease in those at high risk of, suspected or confirmed exposure to Bacillus anthracis. It is subcutaneously or intramuscularly administered. It is derived from cell-free filtrates of microaerophilic cultures of an avirulent, nonencapsulated strain of Bacillus anthracis...
Approved
Oxytocin
Sir Henry H. Dale first identified oxytocin and its uterine contractile properties in 1906.[A229008,A228593,A229108] Like all other neurohypophysial hormones, oxytocin is composed of nine amino acids with a disulfide bridge between the Cys 1 and 6 residues.[A229008,A228593] In the mid-1950s, synthetic oxytocin was successfully synthesized by a biochemist named Vincent...
Approved
Vet approved
Matched Description: … neurohypophysial hormones, oxytocin is composed of nine amino acids with a disulfide bridge between the Cys 1 …
Matched Mixtures name: … Bakumokon 5% Minoxidil …
Matched Products: … Oxytocin-Richter solution for injection 10 I.U / 1 ml ... SYNTOCINON® 5 U.I. ... Syntocinon 5 I.E. Lösung zur Injektion …
Matched Mixtures name: … Bakumokon 5% Minoxidil …
Matched Products: … Oxytocin-Richter solution for injection 10 I.U / 1 ml ... SYNTOCINON® 5 U.I. ... Syntocinon 5 I.E. Lösung zur Injektion …
Parecoxib
Parecoxib is a water-soluble and injectable prodrug of valdecoxib. It is marketed as Dynastat in the European Union. Parecoxib is a COX2 selective inhibitor in the same category as celecoxib (Celebrex) and rofecoxib (Vioxx). As it is injectable, it can be used perioperatively when patients are unable to take oral...
Approved
Matched Synonyms: … N-((p-(5-methyl-3-phenyl-4-isoxazolyl)phenyl)sulfonyl)propionamide …
Matched Iupac: … N-[4-(5-methyl-3-phenyl-1,2-oxazol-4-yl)benzenesulfonyl]propanamide …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Iupac: … N-[4-(5-methyl-3-phenyl-1,2-oxazol-4-yl)benzenesulfonyl]propanamide …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Metipranolol
A beta-adrenergic antagonist effective for both beta-1 and beta-2 receptors. It is used as an antiarrhythmic, antihypertensive, and antiglaucoma agent.
Approved
Matched Description: … A beta-adrenergic antagonist effective for both beta-1 and beta-2 receptors. …
Matched Salts cas: … 36592-77-5 …
Matched Salts cas: … 36592-77-5 …
Lifitegrast
Lifitegrast is a FDA approved drug for the treatment of keratoconjunctivitis sicca (dry eye syndrome). It is a tetrahydroisoquinoline derivative and lymphocyte function-associated antigen-1 ( LFA-1) antagonist that was discovered through the rational design process. The ophthalmic solution was approved in July, 2016 under the trade name Xiidra. It has...
Approved
Matched Iupac: … (2S)-2-{[2-(1-benzofuran-6-carbonyl)-5,7-dichloro-1,2,3,4-tetrahydroisoquinolin-6-yl]formamido}-3-(3- …
Matched Description: … It is a tetrahydroisoquinoline derivative and lymphocyte function-associated antigen-1 ( LFA-1) antagonist …
Matched Categories: … Lymphocyte Function-Associated Antigen-1 ... Lymphocyte Function-Associated Antigen-1 Antagonist ... Lymphocyte Function-Associated Antigen-1 Antagonists …
Matched Description: … It is a tetrahydroisoquinoline derivative and lymphocyte function-associated antigen-1 ( LFA-1) antagonist …
Matched Categories: … Lymphocyte Function-Associated Antigen-1 ... Lymphocyte Function-Associated Antigen-1 Antagonist ... Lymphocyte Function-Associated Antigen-1 Antagonists …
Flutamide
An antiandrogen with about the same potency as cyproterone in rodent and canine species.
Approved
Investigational
Thiosulfuric acid
Thiosulfuric acid is available in its salt forms sodium thiosulfate and sodium thiosulfate pentahydrate. Sodium thiosulfate is part of the World Health Organization’s list of essential medicines, and it has a variety of industrial uses, including food preservative, water de-chlorinator and paper pulp bleaching agent. Sodium thiosulfate is rapidly degraded...
Approved
Investigational
Matched Synonyms: … Sulfurothioic S-acid …
Matched Iupac: … dihydroxy-1lambda6-disulfen-1-one …
Matched Mixtures name: … Sodium Polysulthionate, 5-mthf ... Sodium polysulthionate, 5-methyltetrahydrofolate ... Sodium Polysulthionate, 5-methyltetrahydrofolate …
Matched Iupac: … dihydroxy-1lambda6-disulfen-1-one …
Matched Mixtures name: … Sodium Polysulthionate, 5-mthf ... Sodium polysulthionate, 5-methyltetrahydrofolate ... Sodium Polysulthionate, 5-methyltetrahydrofolate …
Turpentine
Turpentine, also known as spirit of turpentine, oil of turpentine, and wood turpentine, is a liquid extracted from live trees, mainly pine, through distillation of resin. It is used as a solvent and base material in organic synthesis reactions. Turpentine is composed of terpenes, mainly the monoterpenes alpha-pinene and beta-pinene...
Approved
Experimental
Matched Mixtures name: … VICKS VAPORUB BUHARLASAN MERHEM, 1 ADET …
Ensulizole
Ensulizole, also known as 2-phenylbenzimidazole-5-sulfonic acid, is a water-soluble sunscreen agent that absorbs strongly at UV-B wavelengths. It is commonly found in cosmetic products and sunscreen formulas in combination with other UV filter compounds due to its minimal protection against UV-A wavelengths. Due to its water solubility, ensulizole is commonly...
Approved
Matched Description: … Ensulizole, also known as 2-phenylbenzimidazole-5-sulfonic acid, is a water-soluble sunscreen agent that …
Matched Mixtures name: … Careone Anti Aging Vitamin Complex 7 in 1 ... Elements Anti Aging Vitamin Complex 7 In 1 ... Shiseido Urban Environment Tinted Uv Protector 1 …
Matched Products: … Covergirl Outlast All Day Stay Fabulous 3-IN-1 Foundation …
Matched Mixtures name: … Careone Anti Aging Vitamin Complex 7 in 1 ... Elements Anti Aging Vitamin Complex 7 In 1 ... Shiseido Urban Environment Tinted Uv Protector 1 …
Matched Products: … Covergirl Outlast All Day Stay Fabulous 3-IN-1 Foundation …
Displaying drugs 476 - 500 of 12845 in total