Displaying drugs 526 - 550 of 10991 in total
Verapamil
Verapamil is a phenylalkylamine calcium channel blocker used in the treatment of high blood pressure, heart arrhythmias, and angina, and was the first calcium channel antagonist to be introduced into therapy in the early 1960s. It is a member of the non-dihydropyridine class of calcium channel blockers, which includes drugs...
Approved
Matched Iupac: … 2-(3,4-dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino}-2-(propan-2-yl)pentanenitrile …
Matched Salts cas: … 152-11-4 …
Matched Mixtures name: … TARKA® SR240/4 TABLETAS. ... VERACOMB MR 240/4 MG KAPSÜL, 28 ADET ... TARKA FORTE 240/4 FILM TABLET, 28 ADET …
Matched Products: … VECLORAN 5 MG/2 ML ... Isoptin 5 mg - Ampullen ... ISOPAMIL 5 MG/2 ML AMPUL, 2 ADET …
Matched Salts cas: … 152-11-4 …
Matched Mixtures name: … TARKA® SR240/4 TABLETAS. ... VERACOMB MR 240/4 MG KAPSÜL, 28 ADET ... TARKA FORTE 240/4 FILM TABLET, 28 ADET …
Matched Products: … VECLORAN 5 MG/2 ML ... Isoptin 5 mg - Ampullen ... ISOPAMIL 5 MG/2 ML AMPUL, 2 ADET …
Nitrofurantoin
Nitrofurantoin is a nitrofuran antibiotic used to treat uncomplicated urinary tract infections.[L6856,L6859,L6862] Nitrofurantoin is converted by bacterial nitroreductases to electrophilic intermediates which inhibit the citric acid cycle as well as synthesis of DNA, RNA, and protein. This drug is more resistant to the development of bacterial resistance because it acts...
Approved
Vet approved
Matched Synonyms: … 5-Nitrofurantoin ... 1-((5-nitrofurfurylidene)amino)hydantoin ... N-(5-Nitrofurfurylidene)-1-aminohydantoin …
Matched Iupac: … 1-[(E)-[(5-nitrofuran-2-yl)methylidene]amino]imidazolidine-2,4-dione …
Matched Salts cas: … 54-87-5 …
Matched Products: … PIYELOSEPTYL 25 MG/5 ML ORAL SUSPANSIYON, 100 ML ... PIYELOSEPTYL 25 MG/5 ML ORAL SUSPANSIYON, 200 ML ... PIYELOSEPTYL 25 MG/5 ML ORAL SUSPANSIYON, 300 ML …
Matched Iupac: … 1-[(E)-[(5-nitrofuran-2-yl)methylidene]amino]imidazolidine-2,4-dione …
Matched Salts cas: … 54-87-5 …
Matched Products: … PIYELOSEPTYL 25 MG/5 ML ORAL SUSPANSIYON, 100 ML ... PIYELOSEPTYL 25 MG/5 ML ORAL SUSPANSIYON, 200 ML ... PIYELOSEPTYL 25 MG/5 ML ORAL SUSPANSIYON, 300 ML …
Thiosulfuric acid
Thiosulfuric acid is available in its salt forms sodium thiosulfate and sodium thiosulfate pentahydrate. Sodium thiosulfate is part of the World Health Organization’s list of essential medicines, and it has a variety of industrial uses, including food preservative, water de-chlorinator and paper pulp bleaching agent. Sodium thiosulfate is rapidly degraded...
Approved
Investigational
Matched Mixtures name: … Sodium Polysulthionate, 5-mthf ... Sodium polysulthionate, 5-methyltetrahydrofolate ... Sodium Polysulthionate, 5-methyltetrahydrofolate …
Deflazacort
Deflazacort, also known as Emflaza, is a corticosteroid prodrug used as an agent to manage Duchenne Muscular Dystrophy (DMD). It is marketed by Marathon Pharmaceuticals and was approved in February 2017 by the FDA.[L6694,FDA label]
Duchenne Muscular Dystrophy is an inherited disorder resulting from mutations of the dystrophin gene, which...
Approved
Investigational
Matched Iupac: … 2-[(1S,2S,4R,8S,9S,11S,12S,13R)-11-hydroxy-6,9,13-trimethyl-16-oxo-5-oxa-7-azapentacyclo[10.8.0.0²,⁹.0⁴,⁸.0¹³,¹⁸ …
Matched Products: … FLANTADIN 30 MG TABLET, 10 ADET …
Matched Products: … FLANTADIN 30 MG TABLET, 10 ADET …
Chlorquinaldol
Chlorquinaldol was used historically as a topical antiseptic under the trade name Sterosan. It was marketed in the 1950s as an iodine-free alternative which was also unrelated to sulfa drugs or hormones. Chlorquinaldol is currently approved by the European Medicines Agency as a combination tablet with promestriene for the treatment...
Approved
Matched Mixtures name: … IMPETEX %0.1 + %1 KREM, 10 G ... NERISONA-C %0,1 + %1 KREM, 10 GR …
Indocyanine green
Approved
Experimental
Matched Iupac: … }-1,1-dimethyl-3-(4-sulfonatobutyl)-1H-benzo[e]indol-3-ium ... sodium 2-{7-[1,1-dimethyl-3-(4-sulfonatobutyl)-1H,2H,3H-benzo[e]indol-2-ylidene]hepta-1,3,5-trien-1-yl …
Dacomitinib
Dacomitinib, designed as (2E)-N-16-4-(piperidin-1-yl) but-2-enamide, is an oral highly selective quinazalone part of the second-generation tyrosine kinase inhibitors which are characterized by the irreversible binding at the ATP domain of the epidermal growth factor receptor family kinase domains. Dacomitinib was developed by Pfizer Inc and approved by the FDA on...
Approved
Investigational
Matched Iupac: … (2E)-N-{4-[(3-chloro-4-fluorophenyl)amino]-7-methoxyquinazolin-6-yl}-4-(piperidin-1-yl)but-2-enamide …
Matched Description: … Dacomitinib, designed as (2E)-N-16-4-(piperidin-1-yl) but-2-enamide, is an oral highly selective quinazalone …
Matched Description: … Dacomitinib, designed as (2E)-N-16-4-(piperidin-1-yl) but-2-enamide, is an oral highly selective quinazalone …
Bioallethrin
Bioallethrin refers to a mixture of two of the allethrin isomers (1R,trans;1R and 1R,trans;1S) in an approximate ratio of 1:1, where both isomers are active ingredients. A mixture of the two same stereoisomers, but in an approximate ratio of R:S in 1:3, is called esbiothrin. A mixture containing only S-forms...
Approved
Experimental
Matched Iupac: … 2-methyl-4-oxo-3-(prop-2-en-1-yl)cyclopent-2-en-1-yl 2,2-dimethyl-3-(2-methylprop-1-en-1-yl)cyclopropane …
Matched Description: … A mixture of the two same stereoisomers, but in an approximate ratio of R:S in 1:3, is called esbiothrin …
Matched Description: … A mixture of the two same stereoisomers, but in an approximate ratio of R:S in 1:3, is called esbiothrin …
Alogliptin
Alogliptin is a selective, orally-bioavailable inhibitor of enzymatic activity of dipeptidyl peptidase-4 (DPP-4). Chemically, alogliptin is prepared as a benzoate salt and exists predominantly as the R-enantiomer (>99%). It undergoes little or no chiral conversion in vivo to the (S)-enantiomer. FDA approved January 25, 2013.
Approved
Matched Iupac: … 2-({6-[(3R)-3-aminopiperidin-1-yl]-3-methyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl}methyl)benzonitrile …
Matched Description: … (DPP-4). ... Alogliptin is a selective, orally-bioavailable inhibitor of enzymatic activity of dipeptidyl peptidase-4 …
Matched Description: … (DPP-4). ... Alogliptin is a selective, orally-bioavailable inhibitor of enzymatic activity of dipeptidyl peptidase-4 …
Dapsone
A sulfone active against a wide range of bacteria but mainly employed for its actions against mycobacterium leprae. Its mechanism of action is probably similar to that of the sulfonamides which involves inhibition of folic acid synthesis in susceptible organisms. It is also used with pyrimethamine in the treatment of...
Approved
Investigational
Matched Synonyms: … 4-(4-aminophenylsulfonyl)aniline ... 4-(4-amino-benzenesulfonyl)-phenylamine ... 4-(4-aminophenylsulfonyl)benzenamine …
Matched Iupac: … 4-(4-aminobenzenesulfonyl)aniline …
Matched Mixtures name: … Dapsone 6% / Niacinamide 4% ... Dapsone 8.5% / Niacinamide 4% ... 011504 Dapsone 8.5% / Niacinamide 4% …
Matched Products: … DAPTOMIX® 5% GEL ... ACNEWELL %5 JEL, 30 GRAM …
Matched Iupac: … 4-(4-aminobenzenesulfonyl)aniline …
Matched Mixtures name: … Dapsone 6% / Niacinamide 4% ... Dapsone 8.5% / Niacinamide 4% ... 011504 Dapsone 8.5% / Niacinamide 4% …
Matched Products: … DAPTOMIX® 5% GEL ... ACNEWELL %5 JEL, 30 GRAM …
Flavone
Approved
Experimental
Matched Synonyms: … 2-Phenyl-4-chromone ... 2-Phenyl-4-benzopyron ... 2-Phenylbenzopyran-4-one …
Matched Iupac: … 2-phenyl-4H-chromen-4-one …
Matched Iupac: … 2-phenyl-4H-chromen-4-one …
Lorazepam
Lorazepam is a short-acting and rapidly cleared benzodiazepine used commonly as a sedative and anxiolytic. It was developed by DJ Richards, presented and marketed initially by Wyeth Pharmaceuticals in the USA in 1977. The first historic FDA label approval is reported in 1985 by the company Mutual Pharm.
Approved
Matched Iupac: … 7-chloro-5-(2-chlorophenyl)-3-hydroxy-2,3-dihydro-1H-1,4-benzodiazepin-2-one …
Matched Products: … Lorazepam Macure 4 mg/ml Injektionslösung …
Matched Products: … Lorazepam Macure 4 mg/ml Injektionslösung …
Gemeprost
Gemeprost is a prostaglandin E1 (PGE1) analog and antiprogestogen used for preoperative dilation of the cervix before surgical abortion. It is available as vaginal suppositories and also used in combination with the antiprogestin and mifepristone for termination of 1st- and 2nd-trimester pregnancy . It is not FDA-approved but available in...
Approved
Withdrawn
Matched Iupac: … methyl (2E)-7-[(1R,2R,3R)-3-hydroxy-2-[(1E,3R)-3-hydroxy-4,4-dimethyloct-1-en-1-yl]-5-oxocyclopentyl] …
Dichlorobenzyl alcohol
Dichlorobenzyl alcohol is a mild antiseptic with a broad spectrum for bacterial and virus associated with mouth and throat infections. Dichlorobenzyl alcohol is considered as an active ingredient found in several marketed OTC products by Health Canada which has categorized this agent as an anatomical therapeutic chemical. On the other...
Approved
Etelcalcetide
Etelcalcetide is a calcimimetic drug for the treatment of secondary hyperparathyroidism in patients undergoing hemodialysis. Etelcalcetide was approved (trade name Parsabiv) for the treatment of secondary hyperparathyroidism (HPT) in adult patients with chronic kidney disease (CKD) on hemodialysis in February, 2017.
Approved
Investigational
Matched Iupac: … (2R)-2-amino-3-{[(2S)-2-{[(1R)-1-{[(1R)-4-carbamimidamido-1-{[(1R)-4-carbamimidamido-1-{[(1R)-4-carbamimidamido ... -1-{[(1R)-1-{[(1R)-4-carbamimidamido-1-carbamoylbutyl]carbamoyl}ethyl]carbamoyl}butyl]carbamoyl}butyl …
Matched Products: … PARSABIV SOLUTION FOR INJECTION 5 mg/mL ... PARSABIV SOLUTION FOR INJECTION 10 mg/2 mL ... PARSABİV 5 MG/1 ML I.V. ENJEKSİYONLUK ÇÖZELTİ, 1 ADET …
Matched Products: … PARSABIV SOLUTION FOR INJECTION 5 mg/mL ... PARSABIV SOLUTION FOR INJECTION 10 mg/2 mL ... PARSABİV 5 MG/1 ML I.V. ENJEKSİYONLUK ÇÖZELTİ, 1 ADET …
Thyrotropin alfa
Thyrotropin alfa is a recombinant form of thyroid stimulating hormone used in performing certain tests in patients who have or have had thyroid cancer. It is also used along with a radioactive agent to destroy remaining thyroid tissue in certain patients who have had their thyroid gland removed because of...
Approved
Vet approved
Von Willebrand factor human
The human von Willebrand factor (vWF) is a human plasma-derived vWF, an endogenous large multimeric plasma glycoprotein involved in hemostasis. It serves a dual role in hemostasis by mediating platelet adhesion and aggregation at the site of blood vessel injury and stabilizing procoagulant factor VIII (FVIII). Exogenous sources of vWF...
Approved
Investigational
Nirsevimab
Nirsevimab (MEDI8897) is a recombinant human immunoglobulin G1 kappa (IgG1ĸ) monoclonal antibody used to prevent respiratory syncytial virus (RSV) lower respiratory tract disease in neonates and infants. It binds to the prefusion conformation of the RSV F protein, a glycoprotein involved in the membrane fusion step of the viral entry...
Approved
Investigational
Daridorexant
Daridorexant, formerly known as nemorexant, is a selective dual orexin receptor antagonist used to treat insomnia. Insomnia is characterized by difficulties with sleep onset and/or sleep maintenance and impairment of daytime functioning. It chronically affects the person's daily functioning and long-term health effects, as insomnia is often associated with comorbidities...
Approved
Matched Iupac: … 5-chloro-2-[(2S)-1-[5-methoxy-2-(2H-1,2,3-triazol-2-yl)benzoyl]-2-methylpyrrolidin-2-yl]-4-methyl-1H- …
Matched Description: … [A244225] It was approved by the FDA on January 10, 2022, under the name QUVIVIQ. ... [A244280] Daridorexant was approved by the European Commission on May 3, 2022, as the first dual orexin …
Matched Description: … [A244225] It was approved by the FDA on January 10, 2022, under the name QUVIVIQ. ... [A244280] Daridorexant was approved by the European Commission on May 3, 2022, as the first dual orexin …
Tivozanib
Renal cell carcinoma (RCC) is responsible for 3% of cancer cases and is one of the 10 most common cancers in adults. The average age of diagnosis is between age 65 to 74. Tivozanib, also known as FOTIVDA, is a kinase inhibitor developed to treat adult patients with relapsed or...
Approved
Investigational
Matched Iupac: … 1-{2-chloro-4-[(6,7-dimethoxyquinolin-4-yl)oxy]phenyl}-3-(5-methyl-1,2-oxazol-3-yl)urea …
Matched Description: … Renal cell carcinoma (RCC) is responsible for 3% of cancer cases[A231314] and is one of the 10 most common ... It was approved on March 10, 2021 by the FDA. …
Matched Description: … Renal cell carcinoma (RCC) is responsible for 3% of cancer cases[A231314] and is one of the 10 most common ... It was approved on March 10, 2021 by the FDA. …
Perflubutane
Perflubutane has been used in trials studying the diagnostic of Liver Mass, Liver Diseases, Liver Metastasis, Portal Hypertension, and Peripheral Artery Disease. It is a cardiovascular drug designed to enable ultrasound to compete more effectively with nuclear stress testing; currently the leading procedure for detecting coronary heart disease.
Approved
Investigational
Varenicline
Varenicline is a prescription medication used to treat smoking addiction. This medication is the first approved nicotinic receptor partial agonist. Specifically, varenicline is a partial agonist of the alpha4/beta2 subtype of the nicotinic acetylcholine receptor. In addition it acts on alpha3/beta4 and weakly on alpha3beta2 and alpha6-containing receptors. A full...
Approved
Investigational
Matched Description: … On March 9, 2015, the U.S. …
Matched Salts cas: … 375815-87-5 …
Matched Salts cas: … 375815-87-5 …
Plicamycin
Plicamycin is an antineoplastic antibiotic produced by Streptomyces plicatus. It has been used in the treatment of testicular cancer, Paget's disease of bone, and, rarely, the management of hypercalcemia. The manufacturer discontinued plicamycin in 2000.
Approved
Investigational
Withdrawn
Matched Iupac: … -2-yl]oxy}-6-{[(2S,4R,5R,6R)-4-{[(2S,4R,5S,6R)-4,5-dihydroxy-6-methyloxan-2-yl]oxy}-5-hydroxy-6-methyloxan ... (2S,3S)-3-[(1S,3S,4R)-3,4-dihydroxy-1-methoxy-2-oxopentyl]-2-{[(2S,4R,5R,6R)-4-{[(2S,4R,5S,6R)-4-{[(2S ... ,4S,5R,6R)-4,5-dihydroxy-4,6-dimethyloxan-2-yl]oxy}-5-hydroxy-6-methyloxan-2-yl]oxy}-5-hydroxy-6-methyloxan …
Simeprevir
Simeprevir is a hepatitis C virus (HCV) NS3/4A protease inhibitor indicated in patient's with HCV genotype 1 for the treatment of chronic hepatitis C virus (HCV) infection. HCV is a single-stranded RNA virus that is categorized into nine distinct genotypes, with genotype 1 being the most common in the United...
Approved
Matched Iupac: … -2-yl]quinolin-4-yl}oxy)-13-methyl-2,14-dioxo-3,13-diazatricyclo[13.3.0.0^{4,6}]octadec-7-ene-4-carboxamide ... (1R,4R,6R,7Z,15R,17R)-N-(cyclopropanesulfonyl)-17-({7-methoxy-8-methyl-2-[4-(propan-2-yl)-1,3-thiazol …
Matched Description: … Simeprevir is also used in treatment of HCV genotype 4 patients with or without cirrhosis and is taken ... sofosbuvir treatment for genotype 1 or PEG-Interferon/ribavirin combination therapy for genotype 1 or 4. …
Matched Salts cas: … 1241946-89-3 …
Matched Categories: … Heterocyclic Compounds, 3-Ring …
Matched Description: … Simeprevir is also used in treatment of HCV genotype 4 patients with or without cirrhosis and is taken ... sofosbuvir treatment for genotype 1 or PEG-Interferon/ribavirin combination therapy for genotype 1 or 4. …
Matched Salts cas: … 1241946-89-3 …
Matched Categories: … Heterocyclic Compounds, 3-Ring …
Methylphenidate
Methylphenidate is a central nervous system stimulant used most commonly in the treatment of Attention-Deficit/Hyperactivity Disorder (ADHD) and for narcolepsy. Also known as the marketed products Ritalin, Concerta, or Biphentin, methylphenidate is used with other treatment modalities (psychological, educational, cognitive behaviour therapy, etc) to improve the following group of developmentally...
Approved
Investigational
Matched Description: … children with ADHD have an abnormality in the dopamine transporter gene (DAT1), the D4 receptor gene (DRD-4) ... Concerta also provides a sustained 10-12 hour effect, allowing for once-daily dosing. ... The MLRTM release system allows for a sustained effect for 10-12 hours, allowing for once-daily dosing …
Matched Salts cas: … 23655-65-4 …
Matched Categories: … Heterocyclic Compounds, 3-Ring …
Matched Products: … Medikinet 5 mg Tabletten ... Medikinet retard 5 mg Hartkapseln mit veränderter Wirkstofffreisetzung ... PROHIPER 10 …
Matched Salts cas: … 23655-65-4 …
Matched Categories: … Heterocyclic Compounds, 3-Ring …
Matched Products: … Medikinet 5 mg Tabletten ... Medikinet retard 5 mg Hartkapseln mit veränderter Wirkstofffreisetzung ... PROHIPER 10 …
Displaying drugs 526 - 550 of 10991 in total