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Displaying drugs 551 - 575 of 733 in total
Investigational
Matched Synonyms: … -4-yl]-4-methyl-1-oxopentan-2-yl]-4-[5-fluoro-2-(4-methylpiperazin-1-yl)-1,3-thiazol-4-yl]benzamide hydrochloride
The structure of adenosine was first described in 1931, though the vasodilating effects were not described in literature until the 1940s. Adenosine is indicated as an adjunct to thallium-201 in myocardial perfusion scintigraphy, though it is rarely used in this indication, having largely been replaced by dipyridamole and [regadenson].[A229833,A229838] Adenosine...
Approved
Investigational
Matched Description: … L31983] though it is rarely used in this indication, having largely been replaced by [dipyridamole] and
Matched Mixtures name: … Lip And Hand Camellia ... Lip And Hand Wild Rose ... Lip And Hand Shea Butter …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Matched Products: … misoli Power Snail and Collagen Hydrog el Mask Pack ... rootree Treetherapy Rejuvenating Eye and Neck Treatment …
Ethambutol is a bacteriostatic agent indicated alongside medications such as isoniazid, rifampin, and pyrazinamide in the treatment of pulmonary tuberculosis. Ethambutol was first described in the literature in 1961. It was developed out of a need for therapies active against isoniazid resistant strains of Mycobacterium tuberculosis. Ethambutol was granted FDA...
Approved
Matched Description: … Ethambutol is a bacteriostatic agent indicated alongside medications such as [isoniazid], [rifampin], and
Matched Salts name: … Ethambutol hydrochloride
Matched Categories: … ethambutol and isoniazid ... rifampicin, ethambutol and isoniazid ... rifampicin, pyrazinamide, ethambutol and isoniazid …
Matched Products: … Ethambutol Hydrochloride ... ETHAMBUTOL HYDROCHLORIDE
Diltiazem is a benzothiazepine derivative with antihypertensive and vasodilating properties. Approved in 1982 by the FDA, it is a member of the non-dihydropyridine calcium channel blockers drug class. It works through various mechanisms of action, but it primarily works by inhibiting the calcium influx into cardiac and vascular smooth muscle...
Approved
Investigational
Matched Description: … Approved in 1982 by the FDA, it is a member of the non-dihydropyridine calcium channel blockers drug ... It works through various mechanisms of action, but it primarily works by inhibiting the calcium influx ... into cardiac and vascular smooth muscle during depolarization. …
Matched Salts name: … Diltiazem hydrochloride
Matched Categories: … Calcium-Regulating Hormones and Agents ... Agents for Treatment of Hemorrhoids and Anal Fissures for Topical Use ... Calcium Channel Blockers ... Calcium Channel Blockers (Nondihydropyridine) ... Miscellaneous Calcium-channel Blocking Agents …
Matched Products: … Diltiazem Hydrochloride ... Diltiazem hydrochloride ... DILTIAZEM HYDROCHLORIDE
Investigational
Matched Synonyms: … Calcium,n,n'-1,2-ethanediylbis(n-((3-hydroxy-2-methyl-5-((phosphonooxy)methyl)-4-pyridinyl)methyl)glycine …
Matched Categories: … Enzymes and Coenzymes …
A narcotic used as a pain medication. It appears to be an agonist at kappa opioid receptors and an antagonist or partial agonist at mu opioid receptors. Nalbuphine is the only opioid analgesic that is not a controlled substance in the United States.
Approved
Matched Description: … It appears to be an agonist at kappa opioid receptors and an antagonist or partial agonist at mu opioid …
Matched Salts name: … Nalbuphine hydrochloride
Matched Products: … Nalbuphine Hydrochloride
Guanfacine, or BS 100-141,[A189838,A189841] is a selective alpha-A2 adrenergic receptor agonist initially indicated for the treatment of hypertension but is now indicated as an extended release tablet for the treatment of ADHD. Guanfacine was first described in the literature in 1974. Guanfacine was granted FDA approval on 27 October 1986.
Approved
Investigational
Matched Salts name: … Guanfacine hydrochloride
Matched Products: … Guanfacine hydrochloride ... Guanfacine Hydrochloride
Experimental
Matched Name: … PHENYLAMINOIMIDAZO(1,2-ALPHA)PYRIDINE
Valaciclovir (valacyclovir), also known as Valtrex, is an antiviral drug that has been used to manage and treat various herpes infections for more than 2 decades. It was initially approved by the FDA in 1995 [FDA label] and marketed by GlaxoSmithKline . Valacyclovir is the L-valine ester of aciclovir. It...
Approved
Investigational
Matched Description: … Valaciclovir (valacyclovir), also known as _Valtrex_, is an antiviral drug that has been used to manage and ... It was initially approved by the FDA in 1995 [FDA label] and marketed by GlaxoSmithKline [L5671]. ... This class of drugs forms an important part of hepatitis, HIV, and cytomegalovirus drug regimens [A175900 …
Matched Salts name: … Valaciclovir hydrochloride ... Valaciclovir hydrochloride monohydrate …
Matched Categories: … Acyclovir and prodrug ... Amino Acids, Peptides, and Proteins ... Nucleosides and Nucleotides ... Nucleosides and Nucleotides Excl. Reverse Transcriptase Inhibitors …
Matched Products: … Valacyclovir Hydrochloride ... Valacyclovir hydrochloride ... VALACICLOVIR HYDROCHLORIDE
Darigabat is under investigation in clinical trial NCT05941442 (A Study to Evaluate Efficacy, Safety, and Tolerability of Darigabat in Participants With Panic Disorder).
Investigational
Matched Synonyms: … 7-ethyl-4-(4'-(ethylsulfonyl)-6-fluoro-2'-methoxybiphenyl-3-yl)-7h-imidazo(4,5-c)-pyridazine ... 7h-imidazo(4,5-c)pyridazine, 7-ethyl-4-(4'-(ethylsulfonyl)-6-fluoro-2'-methoxy(1,1'-biphenyl)-3-yl)- …
Matched Description: … Darigabat is under investigation in clinical trial NCT05941442 (A Study to Evaluate Efficacy, Safety, and
A selective, irreversible inhibitor of Type B monoamine oxidase. It is used in newly diagnosed patients with Parkinson's disease. It may slow progression of the clinical disease and delay the requirement for levodopa therapy. It also may be given with levodopa upon onset of disability. (From AMA Drug Evaluations Annual,...
Approved
Investigational
Vet approved
Matched Description: … It may slow progression of the clinical disease and delay the requirement for levodopa therapy. …
Matched Salts name: … Selegiline hydrochloride
Matched Products: … Selegiline Hydrochloride
Ticlopidine is an effective inhibitor of platelet aggregation. It is a prodrug that is metabolised to an active form, which blocks the ADP receptor that is involved in GPIIb/IIIa receptor activation leading to platelet aggregation. Ticlopidine is marketed under the brand name Ticlid and is indicated for patients who cannot...
Approved
Matched Iupac: … 5-[(2-chlorophenyl)methyl]-4H,5H,6H,7H-thieno[3,2-c]pyridine
Matched Description: … Ticlopidine is marketed under the brand name Ticlid and is indicated for patients who cannot take aspirin ... includes a black-box warning of neutropenia, aplastic anemia, thrombotic thrombocytopenia purpura, and ... agranulocytosis, so it is necessary to monitor patients' WBC and platelets when they are taking ticlopidine …
Matched Salts name: … Ticlopidine hydrochloride
Matched Categories: … Blood and Blood Forming Organs ... Metabolic Side Effects of Drugs and Substances …
Matched Products: … Ticlopidine Hydrochloride ... Ticlopidine hydrochloride
Naftifine is a synthetic, broad spectrum, antifungal agent and allylamine derivative for the topical treatment of tinea pedis, tinea cruris, and tinea corporis caused by the organisms Trichophyton rubrum, Trichophyton mentagrophytes, Trichophyton tonsurans and Epidermophyton floccosum.
Approved
Matched Description: … , Trichophyton mentagrophytes, Trichophyton tonsurans and Epidermophyton floccosum. ... Naftifine is a synthetic, broad spectrum, antifungal agent and allylamine derivative for the topical ... treatment of tinea pedis, tinea cruris, and tinea corporis caused by the organisms Trichophyton rubrum …
Matched Salts name: … Naftifine Hydrochloride
Matched Products: … Naftifine Hydrochloride ... Naftifine hydrochloride
Cyclobenzaprine, a centrally-acting muscle relaxant, was first synthesized in 1961 and has been available for human use since 1977. It was initially studied for use as antidepressant given its structural similarity to tricyclic antidepressants - it differs from Amitriptyline by only a single double bond.[A185039,A184982] Since its approval, it has...
Approved
Matched Description: … Cyclobenzaprine, a centrally-acting muscle relaxant, was first synthesized in 1961[A185039] and has been …
Matched Salts name: … Cyclobenzaprine hydrochloride
Matched Products: … Cyclobenzaprine Hydrochloride ... Cyclobenzaprine hydrochloride
Melphalan is a nitrogen mustard or bischloroethylamine type alkylating agent. It was first synthesized in the early 1950s by substituting L-phenylalanine for the methyl group on nitrogen mustard.[A261150, A261155] Melphalan is used in the treatment of multiple myeloma and ovarian carcinoma. It is also used for high-conditioning before hematopoietic stem...
Approved
Matched Description: … [A261150, A261155] Melphalan is used in the treatment of multiple myeloma and ovarian carcinoma. …
Matched Salts name: … Melphalan hydrochloride
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents …
Matched Products: … Melphalan Hydrochloride ... Melphalan hydrochloride
Ketotifen is a benzocycloheptathiophene derivative with potent antihistaminic and mast cell stabilizing properties. It has a similar structure to some other first-generation antihistamines such as cyproheptadine and azatadine. Ketotifen was first developed in Switzerland in 1970 by Sandoz Pharmaceuticals and was initially marketed for the treatment of anaphylaxis. In the...
Approved
Matched Description: … allergic symptoms and disorders,[A231204] including urticaria, mastocytosis, and food allergy. ... Ketotifen is a benzocycloheptathiophene derivative[A231204] with potent antihistaminic and mast cell ... It has a similar structure to some other first-generation antihistamines such as [cyproheptadine] and
Matched Categories: … Decongestants and Antiallergics …
Matched Products: … Up and Up Eye Itch Relief …
Bendamustine is a nitrogen mustard drug which has been used in the treatment of chronic lymphocytic leukemia (CLL) and indolent B-cell non-Hodgkin lymphoma (NHL). Bendamustine is a bifunctional mechlorethamine derivative capable of forming electrophilic alkyl groups that covalently bond to other molecules. Through this function as an alkylating agent, bendamustine...
Approved
Investigational
Matched Description: … a nitrogen mustard drug which has been used in the treatment of chronic lymphocytic leukemia (CLL) and ... Through this function as an alkylating agent, bendamustine causes intra- and inter-strand crosslinks ... It is active against both active and quiescent cells, although the exact mechanism of action is unknown …
Matched Salts name: … Bendamustine hydrochloride ... Bendamustine hydrochloride monohydrate …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … Bendamustine Hydrochloride ... Bendamustine Hydrochloride for Injection ... Bendamustine Hydrochloride Kabi 25mg Powder for Concentrate for Solution for Infusion …
Pimasertib is under investigation in clinical trial NCT01378377 (Combination Trial of Pimasertib (MSC1936369B) With Temsirolimus).
Investigational
Matched Synonyms: … N-[(2S)-2,3-dihydroxypropyl]-3-(2-fluoro-4-iodoanilino)pyridine-4-carboxamide …
Matched Iupac: … N-[(2S)-2,3-dihydroxypropyl]-3-[(2-fluoro-4-iodophenyl)amino]pyridine-4-carboxamide …
Matched Salts name: … Pimasertib hydrochloride
Desloratadine is a second generation, tricyclic antihistamine that which has a selective and peripheral H1-antagonist action. It is the active descarboethoxy metabolite of loratidine (a second generation histamine). Desloratidine has a long-lasting effect and does not cause drowsiness because it does not readily enter the central nervous system.
Approved
Investigational
Matched Synonyms: … 8-Chloro-11-piperidin-4-ylidene-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridine ... 8-chloro-6,11-dihydro-11-(4-piperidinylidene)-5H-benzo(5,6)cyclohepta(1,2-b)pyridine
Matched Description: … Desloratadine is a second generation, tricyclic antihistamine that which has a selective and peripheral ... Desloratidine has a long-lasting effect and does not cause drowsiness because it does not readily enter …
Matched Categories: … Loratadine and derivatives …
Cefotaxime is a third-generation cephalosporin antibiotic. Like other third-generation cephalosporins, it has broad spectrum activity against Gram positive and Gram negative bacteria. In most cases, it is considered to be equivalent to ceftriaxone in terms of safety and efficacy. Cefotaxime sodium is marketed under various trade names including Claforan (Sanofi-Aventis).
Approved
Matched Description: … Like other third-generation cephalosporins, it has broad spectrum activity against Gram positive and ... In most cases, it is considered to be equivalent to ceftriaxone in terms of safety and efficacy. …
Matched Products: … Cefotaxime and Dextrose …
Sodium bicarbonate is a white, crystalline powder that is commonly used as a pH buffering agent, an electrolyte replenisher, systemic alkalizer and in topical cleansing solutions.
Approved
Matched Description: … powder that is commonly used as a pH buffering agent, an electrolyte replenisher, systemic alkalizer and
Matched Mixtures name: … bicaVera 1,5 % Glucose, 1,25 mmol/l Calcium, Peritonealdialyselösung ... bicaVera 2,3 % Glucose, 1,25 mmol/l Calcium, Peritonealdialyselösung ... bicaVera 4,25 % Glucose, 1,25 mmol/l Calcium, Peritonealdialyselösung …
Matched Categories: … Antacids and Adsorbents ... Blood and Blood Forming Organs ... Blood Substitutes and Perfusion Solutions …
Matched Products: … Arm and Hammer Baking Soda …
Methylphenidate is a central nervous system stimulant used most commonly in the treatment of Attention-Deficit/Hyperactivity Disorder (ADHD) and for narcolepsy. Also known as the marketed products Ritalin, Concerta, or Biphentin, methylphenidate is used with other treatment modalities (psychological, educational, cognitive behaviour therapy, etc) to improve the following group of developmentally...
Approved
Investigational
Matched Description: … and working memory. ... the most effective and widely used treatment for ADHD, and are considered first-line options for children ... addictive properties of psychostimulants such as methylphenidate, and even amplifies the potency and
Matched Salts name: … Methylphenidate hydrochloride
Matched Categories: … Methylphenidate and isomer ... Respiratory and CNS Stimulants ... Psychostimulants, Agents Used for ADHD and Nootropics …
Matched Products: … Methylphenidate Hydrochloride ... Methylphenidate hydrochloride ... Methylphenidate Hydrochloride SR …
Antihistamines such as azatadine appear to compete with histamine for histamine H1- receptor sites on effector cells. The antihistamines antagonize those pharmacological effects of histamine which are mediated through activation of H1- receptor sites and thereby reduce the intensity of allergic reactions and tissue injury response involving histamine release.
Approved
Matched Synonyms: … 11-(1-Methyl-4-piperidinylidene)-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridine ... 6,11-Dihydro-11-(1-methyl-4-piperidylidene)-5H-benzo(5,6)cyclohepta(1,2-b)pyridine
Matched Description: … those pharmacological effects of histamine which are mediated through activation of H1- receptor sites and ... thereby reduce the intensity of allergic reactions and tissue injury response involving histamine release …
A benzodiazepine derivative used mainly as a hypnotic.
Approved
Illicit
Investigational
Matched Salts name: … Flurazepam hydrochloride
Matched Categories: … Hypnotics and Sedatives ... Benzodiazepines and benzodiazepine derivatives …
Matched Products: … Flurazepam Hydrochloride
Avoralstat has been used in trials studying the prevention of HAE and Hereditary Angioedema.
Investigational
Matched Synonyms: … 3-(2-((4-Carbamimidoylphenyl)carbamoyl)-4-ethenyl-5-methoxyphenyl)-6-((cyclopropylmethyl)carbamoyl)pyridine ... 3-[2-(4-carbamimidoyl-phenylcarbamoyl)-5-methoxy-4-vinyl-phenyl]-6-(cyclopropylmethyl-carbamoyl)-pyridine ... 3-[2-[(4-carbamimidoylphenyl)carbamoyl]-4-ethenyl-5-methoxyphenyl]-6-(cyclopropylmethylcarbamoyl)pyridine
Matched Iupac: … 3-{2-[(4-carbamimidoylphenyl)carbamoyl]-4-ethenyl-5-methoxyphenyl}-6-[(cyclopropylmethyl)carbamoyl]pyridine
Matched Description: … Avoralstat has been used in trials studying the prevention of HAE and Hereditary Angioedema. …
Displaying drugs 551 - 575 of 733 in total