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Displaying drugs 601 - 625 of 11979 in total
Cholesterol
The principal sterol of all higher animals, distributed in body tissues, especially the brain and spinal cord, and in animal fats and oils.
Approved
Investigational
Matched Description: … cord, and in animal fats and oils. ... The principal sterol of all higher animals, distributed in body tissues, especially the brain and spinal …
Crisaborole
Crisaborole is a novel oxaborole approved by FDA on December 14, 2016 as Eucrisa, a topical treatment of for mild to moderate atopic dermatitis.
This non-steroidal agent is efficacious in improving disease severity, reducing the risk of infection and reducing the signs and symptoms in patients 2 years old and...
Approved
Investigational
Matched Description: … and reducing the signs and symptoms in patients 2 years old and older. ... This non-steroidal agent is efficacious in improving disease severity, reducing the risk of infection ... It reduces the local inflammation in the skin and prevents further exacerbation of the disease with a …
Chymopapain
Chymopapain was first isolated in 1941 from the crude latex derived from the fruit of Carica papaya by squeezing the green papaya while on the plant prior to harvest. It is an extracellular plant cysteine proteinase similar to papain in specificity. Chymopapain was developed by Chart Medcl and FDA approved...
Approved
Withdrawn
Matched Description: … [L2482]It is an extracellular plant cysteine proteinase similar to papain in specificity. ... Chymopapain was first isolated in 1941 from the crude latex derived from the fruit of Carica papaya by …
Red king crab
Crab allergenic extract is used in allergenic testing.
Approved
Matched Description: … Crab allergenic extract is used in allergenic testing. …
Sweet cherry
Sweet cherry allergenic extract is used in allergenic testing.
Approved
Matched Description: … Sweet cherry allergenic extract is used in allergenic testing. …
Colchiceine
Colchiceine is one of several metabolites of the anti-gout medication colchicine.
Approved
Experimental
Cashew fruit
Cashew fruit extract is used in allergenic testing.
Approved
Matched Description: … Cashew fruit extract is used in allergenic testing. …
Cinnamon oil
Approved
Experimental
Chlorzoxazone
A centrally acting central muscle relaxant with sedative properties. It is claimed to inhibit muscle spasm by exerting an effect primarily at the level of the spinal cord and subcortical areas of the brain. (From Martindale, The Extra Pharmacopoea, 30th ed, p1202)
Approved
Aceclofenac
Aceclofenac is an oral non-steroidal anti-inflammatory drug (NSAID) with marked anti-inflammatory and analgesic properties used to treat osteoarthritis, rheumatoid arthritis and ankylosing spondylitis. It is reported to have a higher anti-inflammatory action or at least comparable effects than conventional NSAIDs in double-blind studies [A19667, A19668, A19670]. Aceclofenac potently inhibits the...
Approved
Investigational
Matched Description: … It is a more commonly prescribed drug in Europe. ... modification in effort to improve the gastrointestinal tolerability of the drug. ... It displays high permeability to penetrate into synovial joints where in patients with osteoarthritis …
Manganese citrate
Approved
Experimental
Chymotrypsin
Chymotrypsin (EC 3.4.21.1) is a digestive enzyme that promotes proteolysis, or the breakdown of proteins and polypeptides. It is a serine protease synthesized in the pancreas and is a vital component in the pancreatic juice. Like most proteolytic enzymes, chymotrypsin is activated from its inactive zymogen precursor, chymotrypsinogen, in presence...
Approved
Vet approved
Matched Description: … It is a serine protease synthesized in the pancreas and is a vital component in the pancreatic juice. ... proteolytic enzymes, chymotrypsin is activated from its inactive zymogen precursor, chymotrypsinogen, in …
Tetryzoline
Tetryzoline, also known as tetrahydrozoline, is a derivative of imidazoline with central and peripheral alpha (α)-adrenergic properties. Available since the 1950s, tetryzoline is a selective α1-receptor agonist that is used as an ocular and nasal decongestant. Tetryzoline is found in a wide array of over-the-counter eye drops, including the most...
Approved
Matched Description: … , corticosteroids, and glucocorticoids in other countries. ... Tetryzoline is found in a wide array of over-the-counter eye drops, including the most common brand, ... [L32579] Tetryzoline is also found in combination products with other lubricants and anti-irritants, …
Matched Mixtures name: … Rohto All-In-One …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Mixtures name: … Rohto All-In-One …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Cabotegravir
Cabotegravir, or GSK1265744, is an HIV-1 integrase inhibitor that is prescribed with the non-nucleoside reverse transcriptase inhibitor, rilpivirine.[A227668,L31188,L31193] Early research into cabotegravir showed it had lower oral bioavailability than dolutegravir, which resulted in the development of long acting monthly intramuscular injection formulation for cabotegravir.[A227668,L31193]
Cabotegravir was granted FDA approval on...
Approved
Investigational
Matched Description: … to treat HIV-1 infection in virologically suppressed individuals. ... cabotegravir showed it had lower oral bioavailability than [dolutegravir],[A227668] which resulted in ... [A227668,L31193]
Cabotegravir was granted FDA approval on 21 January 2021 in combination with rilpivirine …
Dostarlimab
Dostarlimab is an IgG4 humanized monoclonal antibody targeted against the human programmed death receptor-1 (PD-1). PD-1 receptors are found on T-cells and, when activated, serve to inhibit immune responses - some cancers leverage this system by overexpressing PD-1 ligands, thereby effectively inhibiting the anti-tumor immune response that would typically attempt...
Approved
Investigational
Matched Description: … resulted in all twelve patients exhibiting a complete clinical response. ... L45161] Dostarlimab-gxly was granted second accelerated approval for the treatment of solid tumours in ... A prospective phase II study in patients with mismatch repair-deficient locally advanced rectal cancer …
Zoledronic acid
Zoledronic acid, or CGP 42'446, is a third generation, nitrogen containing bisphosphonate similar to ibandronic acid, minodronic acid, and risedronic acid. Zoledronic acid is used to treat and prevent multiple forms of osteoporosis, hypercalcemia of malignancy, multiple myeloma, bone metastases from solid tumors, and Paget’s disease of bone.[L13712,L13715,L13721] Zoledronic acid...
Approved
Matched Description: … [L13712,L13715,L13721] Zoledronic acid was first described in the literature in 1994. …
Chloroprocaine
Chloroprocaine is an ester local anesthetic commonly available in its salt form, chloroprocaine hydrochloride. Similar to other local anesthetics, it increases the threshold for electrical excitation in nerves by slowing the propagation of the nerve impulse and reducing the rate of rise of the action potential. The pharmacological profile of...
Approved
Investigational
Matched Description: … Similar to other local anesthetics, it increases the threshold for electrical excitation in nerves by ... Chloroprocaine is an ester local anesthetic commonly available in its salt form, chloroprocaine hydrochloride ... [A252952,L43382] Topical chloroprocaine for ophthalmic use was approved by the FDA in September 2022 …
Corydalis ambigua tuber
Corydalis ambigua tuber is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Approved
Experimental
Matched Description: … Corydalis ambigua tuber is a plant/plant extract used in some OTC (over-the-counter) products. …
Tubocurarine
Tubocurarine is a non-depolarizing neuromuscular blocking agent and the first identified curare alkaloid. Curare is one of the names used to describe plant-derived poisons used by indigenous South Americans to coat the tips of hunting arrows and darts, which were typically derived from plants of the genera Chondrodendron and Strychnos....
Approved
Matched Description: … [A216028] It was first isolated by Harold King in 1935 and was used clinically to induce neuromuscular ... non-depolarizing neuromuscular blockers, such as [rocuronium], have largely replaced the use of tubocurarine in …
Rose bengal
Rose bengal is a pink stain derived as an analogue of fluorescein. Its disodium salt in ophthalmic solutions has been used as a diagnostic agent in suspected damage to conjunctival and corneal cells. It is also used in laboratory settings, including the preparation of Foraminifera for microscopic analysis and suppression...
Approved
Investigational
Matched Description: … Its disodium salt in ophthalmic solutions has been used as a diagnostic agent in suspected damage to ... and suppression of bacterial growth in several microbiological media. ... The clinical applications of rose bengal as injectable formulation under the name PV-10 in melanoma, …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Ethambutol
Ethambutol is a bacteriostatic agent indicated alongside medications such as isoniazid, rifampin, and pyrazinamide in the treatment of pulmonary tuberculosis. Ethambutol was first described in the literature in 1961. It was developed out of a need for therapies active against isoniazid resistant strains of Mycobacterium tuberculosis. Ethambutol was granted FDA...
Approved
Matched Description: … [L31743] Ethambutol was first described in the literature in 1961. ... bacteriostatic agent indicated alongside medications such as [isoniazid], [rifampin], and [pyrazinamide] in …
Chlorambucil
A nitrogen mustard alkylating agent used as antineoplastic agent for the treatment of various malignant and nonmalignant diseases. Although it is less toxic than most other nitrogen mustards, it has been listed as a known carcinogen in the Fourth Annual Report on Carcinogens (NTP 85-002, 1985). (Merck Index, 11th ed)
Approved
Matched Description: … Although it is less toxic than most other nitrogen mustards, it has been listed as a known carcinogen in …
Medroxyprogesterone acetate
Medroxyprogesterone acetate (MPA) is a progesterone derivative that is more resistant to metabolism for improved pharmacokinetic properties. MPA can be use to treat secondary amenorrhea, endometrial hyperplasia, abnormal uterine bleeding, osteoporosis, vasomotor symptoms in menopause, vulvar and vaginal atrophy, prevent pregnancy, manage pain in endometriosis, prevent pregnancy, and is also...
Approved
Investigational
Matched Description: … , and is also used in palliative care for endometrial and renal carcinoma. ... menopause, vulvar and vaginal atrophy, prevent pregnancy, manage pain in endometriosis, prevent pregnancy ... secondary amenorrhea, endometrial hyperplasia, abnormal uterine bleeding, osteoporosis, vasomotor symptoms in …
Cyclobenzaprine
Cyclobenzaprine, a centrally-acting muscle relaxant, was first synthesized in 1961 and has been available for human use since 1977. It was initially studied for use as antidepressant given its structural similarity to tricyclic antidepressants - it differs from Amitriptyline by only a single double bond.[A185039,A184982] Since its approval, it has...
Approved
Matched Description: … Cyclobenzaprine, a centrally-acting muscle relaxant, was first synthesized in 1961[A185039] and has been …
Displaying drugs 601 - 625 of 11979 in total