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Displaying drugs 51 - 75 of 11729 in total
A centrally acting central muscle relaxant with sedative properties. It is claimed to inhibit muscle spasm by exerting an effect primarily at the level of the spinal cord and subcortical areas of the brain. (From Martindale, The Extra Pharmacopoea, 30th ed, p1202)
Approved
Matched Synonyms: … 5-chloro-2-benzoxazolol ... 5-chloro-2-benzoxazolone ... 5-chloro-2-benzoxazolinone …
Matched Iupac: … 5-chloro-2,3-dihydro-1,3-benzoxazol-2-one …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Balsalazide is an anti-inflammatory drug used in the treatment of Inflammatory Bowel Disease. It is sold under the name "Colazal" in the US and "Colazide" in the UK. The chemical name is (E)-5-[[-4-(2-carboxyethyl) aminocarbonyl] phenyl]azo] -2-hydroxybenzoic acid. It is usually administered as the disodium salt. Balsalazide works by deliverying mesalazine...
Approved
Investigational
Matched Synonyms: … (E)-5-({p-[(2-carboxyethyl)carbamoyl]phenyl}azo)-2-salicylic acid ... (E)-5-((4-(((2-carboxyethyl)amino)carbonyl)phenyl)azo)-2-hydroxybenzoic acid ... 5-[4-(2-carboxy-ethylcarbamoyl)-phenylazo]-2-hydroxy-benzoic acid …
Matched Iupac: … 5-[(1E)-2-{4-[(2-carboxyethyl)carbamoyl]phenyl}diazen-1-yl]-2-hydroxybenzoic acid …
Matched Description: … The chemical name is (E)-5-[[-4-(2-carboxyethyl) aminocarbonyl] phenyl]azo] -2-hydroxybenzoic acid. …
Matched Categories: … Non COX-2 selective NSAIDS …
A dideoxynucleoside compound in which the 3'-hydroxyl group on the sugar moiety has been replaced by a hydrogen. This modification prevents the formation of 5' to 3' phosphodiester linkages, which are needed for the elongation of DNA chains, thus resulting in the termination of viral DNA growth. The compound is...
Approved
Investigational
Matched Synonyms: … 2',3'-Dideoxycytidine ... 4-amino-1-[(2R,5S)-5-(hydroxymethyl)tetrahydrofuran-2-yl]pyrimidin-2(1H)-one …
Matched Iupac: … 4-amino-1-[(2R,5S)-5-(hydroxymethyl)oxolan-2-yl]-1,2-dihydropyrimidin-2-one …
Propiomazine, an atypical antipsychotic agent, is used to treat both negative and positive symptoms of schizophrenia, acute mania with bipolar disorder, agitation, and psychotic symptoms in dementia. Future uses may include the treatment of obsessive-compulsive disorder and severe behavioral disorders in autism. Structurally and pharmacologically similar to clozapine, propiomazine binds...
Approved
Matched Synonyms: … 10-(2-Dimethylaminopropyl)-2-propionylphenothiazine ... 2-Propionyl-10-(2-(dimethylamino)propyl)phenothiazine …
Matched Iupac: … 1-{10-[2-(dimethylamino)propyl]-10H-phenothiazin-2-yl}propan-1-one …
Matched Description: … to clozapine, propiomazine binds to alpha(1), dopamine, histamine H1, muscarinic, and serotonin type 2
Antiarrhythmic agent pharmacologically similar to lidocaine. It may have some anticonvulsant properties.
Approved
Investigational
Matched Synonyms: … 1-(2',6'-dimethylphenoxy)-2-aminopropane ... 1-methyl-2-(2,6-xylyloxy)ethanamine ... (±)-1-(2,6-dimethylphenoxy)propan-2-amine …
Matched Iupac: … 1-(2,6-dimethylphenoxy)propan-2-amine …
Viloxazine is a selective norepinephrine reuptake inhibitor. For decades, an immediate-release formulation of viloxazine has been used in Europe as an antidepressant. It was first approved in the UK in 1974; however, the immediate-release formulation was discontinued due to business reasons unrelated to drug safety and efficacy. In the US,...
Approved
Investigational
Withdrawn
Matched Synonyms: … 2-((2-Ethoxyphenoxy)methyl)morpholine …
Matched Iupac: … 2-[(2-ethoxyphenoxy)methyl]morpholine …
Matched Salts cas: … 35604-67-2
Povidone, also known as polyvinylpyrrolidone (PVP) or polyvidone, is a synthetic water-soluble polymer made from the monomer N-vinylpyrrolidone used as a binder in many pharmaceutical tablets and lubricant in eye drops. It is also used in many technical applications with various roles as an adhesive, additive, and emulsifier. When in...
Approved
Withdrawn
Matched Synonyms: … 1-vinyl-2-pyrrolidinone polymer ... 1-ethenyl-2-pyrrolidinone homopolymer …
Matched Products: … VIDISEPT 2% …
Eprosartan is an angiotensin II receptor antagonist used to treat hypertension. It performs 2 actions on the renin angiotensin system. By preventing the binding of angiotensin II to AT1, vascular smooth muscle relaxes and vasodilation occurs. By inhibiting norepinephrine production, blood pressure is further reduced.
Approved
Matched Synonyms: … (E)-3-[2-n-butyl-1-{(4-carboxyphenyl)methyl}-1H-imidazol-5-yl]-2-(2-thienyl)methyl-2-propenoic acid ... (E)-2-butyl-1-(p-carboxybenzyl)-α-2-thenylimidazole-5-acrylic acid ... (E)-α{[2-butyl-1-[(4-carboxyphenyl)methyl]-1H-imidazole-5-yl]methylene}-2-thiopheneproprionic acid …
Matched Iupac: … 4-({2-butyl-5-[(1E)-2-carboxy-2-[(thiophen-2-yl)methyl]eth-1-en-1-yl]-1H-imidazol-1-yl}methyl)benzoic …
Matched Description: … It performs 2 actions on the renin angiotensin system. …
Matched Categories: … Angiotensin 2 Receptor Blocker …
Lumiracoxib is a COX-2 selective non-steroidal anti-inflammatory drug (NSAID). On August 11, 2007, Australia's Therapeutic Goods Administration (TGA, the Australian equivalent of the FDA) cancelled the registration of lumiracoxib in Australia due to concerns that it may cause liver failure. New Zealand and Canada have also followed suit in recalling...
Approved
Investigational
Matched Synonyms: … 2-((2-chloro-6-fluorophenyl)amino)-5-methylbenzeneacetic acid …
Matched Iupac: … 2-{2-[(2-chloro-6-fluorophenyl)amino]-5-methylphenyl}acetic acid …
Matched Description: … Lumiracoxib is a COX-2 selective non-steroidal anti-inflammatory drug (NSAID). …
Matched Categories: … COX-2 Inhibitors ... Selective Cyclooxygenase 2 Inhibitors (NSAIDs) …
Approved
Matched Synonyms: … Iron(2+) gluconate (1:2) ... D-gluconic acid, iron(2+) salt (2:1) …
Matched Iupac: … lambda2-iron(2+) bis((2R,3S,4R,5R)-2,3,4,5,6-pentahydroxyhexanoate) …
Matched Mixtures name: … Swical-energy-2
Cisatracurium is a non-depolarising neuromuscular blocking agent of the benzylisoquinolinium class, available in its salt form, cisatracurium besylate.[A243416,A253592] Cisatracurium has an intermediate duration of action and is one of the most commonly used neuromuscular blocking agents in intensive care.[A253592,A253597]. Cisatracurium acts on cholinergic receptors, blocking neuromuscular transmission. This action is...
Approved
Investigational
Matched Synonyms: … -dimethoxy-2-methyl-1,2,3,4-tetrahydroisoquinolinium] ... (1r,2r,1'r,2'r)-2,2'-{pentane-1,5-diylbis[oxy(3-oxopropane-3,1-diyl)]}bis[1-(3,4-dimethoxybenzyl)-6,7 …
Matched Iupac: … -2-methyl-1,2,3,4-tetrahydroisoquinolin-2-ium ... -2-methyl-1,2,3,4-tetrahydroisoquinolin-2-ium-2-yl]propanoyl}oxy)pentyl]oxy}-3-oxopropyl)-6,7-dimethoxy ... (1R,2R)-1-[(3,4-dimethoxyphenyl)methyl]-2-(3-{[5-({3-[(1R,2R)-1-[(3,4-dimethoxyphenyl)methyl]-6,7-dimethoxy …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Products: … Nimbex Injection 2 mg/ml ... นิมเบ็กซ์ (ชนิดฉีด 2 มก./มล.) ... Nimbex 2 mg/ml - Injektions-/Infusionslösung …
Axitinib is a second generation tyrosine kinase inhibitor that works by selectively inhibiting vascular endothelial growth factor receptors (VEGFR-1, VEGFR-2, VEGFR-3). Through this mechanism of action, axitinib blocks angiogenesis, tumour growth and metastases. It is reported to exhibit potency that is 50-450 times higher than that of the first generation...
Approved
Investigational
Matched Synonyms: … N-methyl-2-[[3-[(E)-2-pyridin-2-ylethenyl]-1H-indazol-6-yl]sulfanyl]benzamide …
Matched Iupac: … N-methyl-2-({3-[(E)-2-(pyridin-2-yl)ethenyl]-1H-indazol-6-yl}sulfanyl)benzamide …
Matched Description: … inhibitor that works by selectively inhibiting vascular endothelial growth factor receptors (VEGFR-1, VEGFR-2, …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Tiaprofenic acid is a non-steroidal anti-inflammatory drug employed in the treatment of pain, particularly arthritis pain. It belongs to the arylpropionic acid (profen) group of nonsteroidal anti-inflammatory drugs (NSAIDs).
Approved
Matched Synonyms: … 2-(5-Benzyl-2-thienyl)propionsäure ... 2-(5-Benzoyl-thiophen-2-yl)-propionic acid ... 5-benzoyl-α-methyl-2-thiopheneacetic acid …
Matched Iupac: … 2-(5-benzoylthiophen-2-yl)propanoic acid …
Matched Categories: … Non COX-2 selective NSAIDS …
Tetryzoline, also known as tetrahydrozoline, is a derivative of imidazoline with central and peripheral alpha (α)-adrenergic properties. Available since the 1950s, tetryzoline is a selective α1-receptor agonist that is used as an ocular and nasal decongestant. Tetryzoline is found in a wide array of over-the-counter eye drops, including the most...
Approved
Matched Synonyms: … 2-(1,2,3,4-Tetrahydro-1-naphthyl)-2-imidazoline ... 2-Tetralin-1-yl-4,5-dihydro-1H-imidazole ... (RS)-2-(1,2,3,4-tetrahydronaphthalen-1-yl)-4,5-dihydro-1H-imidazole …
Matched Iupac: … 2-(1,2,3,4-tetrahydronaphthalen-1-yl)-4,5-dihydro-1H-imidazole …
Matched Products: … Murine Plus 2
Antazoline is a 1st generation antihistamine with anticholinergic activity. It is used to relieve nasal congestion. It is also formulated as eye drops with naphazoline to relieve allergic conjunctivitis.
Approved
Matched Synonyms: … 2-(N-Benzylanilinomethyl)-2-imidazoline ... 2-(N-Phenyl-N-benzylaminomethyl)imidazoline ... 4,5-Dihydro-N-phenyl-N-phenylmethyl-1H-imidazole-2-methanamine …
Matched Iupac: … N-benzyl-N-[(4,5-dihydro-1H-imidazol-2-yl)methyl]aniline …
Sulfasalazine is an anti-inflammatory drug structurally related to salicylates and other non-steroidal anti-inflammatory drugs. It is indicated for managing inflammatory diseases such as ulcerative colitis and rheumatoid arthritis (RA).[L39065, A255582] Metabolized by intestinal bacteria, sulfasalazine is broken down into mesalazine and sulfapyridine, 2 compounds that carry out the main pharmacological...
Approved
Matched Synonyms: … 2-Hydroxy-5-((4-((2-pyridinylamino)sulfonyl)phenyl)azo)benzoic acid ... 2-Hydroxy-5-[4-(pyridin-2-ylsulfamoyl)-phenylazo]-benzoic acid ... 5-(4-(2-Pyridylsulfamoyl)phenylazo)-2-hydroxybenzoic acid …
Matched Iupac: … 2-hydroxy-5-[(E)-2-{4-[(pyridin-2-yl)sulfamoyl]phenyl}diazen-1-yl]benzoic acid …
Matched Description: … Metabolized by intestinal bacteria, sulfasalazine is broken down into [mesalazine] and [sulfapyridine], 2
Matched Categories: … Non COX-2 selective NSAIDS …
A histamine congener, it competitively inhibits histamine binding to histamine H2 receptors. Cimetidine has a range of pharmacological actions. It inhibits gastric acid secretion, as well as pepsin and gastrins output. It also blocks the activity of cytochrome P-450 which might explain proposals for use in neoadjuvant therapy.
Approved
Investigational
Matched Synonyms: … 1-Cyano-2-methyl-3-(2-(((5-methyl-4-imidazolyl)methyl)thio)ethyl)guanidine ... 2-cyano-1-methyl-3-(2-(((5-methylimidazol-4-yl)methyl)thio)ethyl)guanidine ... N''-cyano-N-methyl-N'-(2-{[(5-methyl-1H-imidazol-4-yl)methyl]thio}ethyl)guanidine …
Matched Iupac: … (Z)-N''-cyano-N-methyl-N'-(2-{[(5-methyl-1H-imidazol-4-yl)methyl]sulfanyl}ethyl)guanidine …
Matched Salts cas: … 70059-30-2
Matched Mixtures name: … Cimetidine 5% / Ibuprofen 2% / Salicylic Acid 17% …
Matched Categories: … MATE 2 Inhibitors ... MATE 2 Substrates …
A semi-synthetic cephalosporin antibiotic.
Approved
Matched Synonyms: … oct-2-ene-2-carboxylic acid ... ]oct-2-ene-2-carboxylic acid ... 7-(D-2-Amino-2-(1,4-cyclohexadienyl)acetamide)desacetoxycephalosporanicacid …
Matched Iupac: … ]oct-2-ene-2-carboxylic acid ... (6R,7R)-7-[(2R)-2-amino-2-(cyclohexa-1,4-dien-1-yl)acetamido]-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0 …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Florbetapir (18F) is a radiopharmaceutical compound containing the radionuclide fluorine-18 bound to the compound florbetapir, a molecule that binds with high affinity to beta amyloid plaque, a peptide that plays a key role in Alzheimer's Disease pathogenesis. Marketed as the product Amyvid, florbetapir 18F is indicated for positron emission tomography...
Approved
Investigational
Matched Synonyms: … 4-{(E)-2-[6-(2-{2-[2-(18F)fluoroethoxy]ethoxy}ethoxy)pyridin-3-yl]ethenyl}-N-methylaniline …
Matched Iupac: … 4-[(E)-2-[6-(2-{2-[2-(¹⁸F)fluoroethoxy]ethoxy}ethoxy)pyridin-3-yl]ethenyl]-N-methylaniline …
Secnidazole is a second-generation 5-nitroimidazole antimicrobial agent. It is structurally related to other 5-nitroimidazoles, including DB00916 and DB00911, but displays improved oral absorption and a longer terminal elimination half-life than other drugs in this class. Secnidazole is selective against many anaerobic Gram-positive and Gram-negative bacteria as well as protozoa. Once...
Approved
Matched Synonyms: … 1-(2­ hydroxypropyl)-2-methyl-5-nitroimidazole ... 1-(2-methyl-5-nitro-1H-imidazol-1-yl) propan-2­ ol …
Matched Iupac: … 1-(2-methyl-5-nitro-1H-imidazol-1-yl)propan-2-ol …
Matched Products: … SECNIZOL® 2 G ... SECNIDOX 1000 MG FILM TABLET,2 ADET ... SECNIDOX 500 MG FILM TABLET ,2 FILM TABLET …
Methocarbamol was developed in the early 1950s as a treatment for muscle spasticity and the associated pain.[A178441,A178450] It is a guaiacol glyceryl ether. Methocarbamol tablets and intramuscular injections are prescription medicines indicated in the United States as an adjunct to rest, physical therapy, and other measures for the relief of...
Approved
Vet approved
Matched Synonyms: … (RS)-2-hydroxy-3-(2-methoxyphenoxy)propyl carbamate …
Matched Iupac: … 2-hydroxy-3-(2-methoxyphenoxy)propyl carbamate …
Matched Mixtures name: … Robaxisal C 1/2 ... Methoxisal-C 1/2
Carprofen is a non-steroidal anti-inflammatory drug (NSAID) that is used by veterinarians as a supportive treatment for the relief of arthritic symptoms in geriatric dogs. Carprofen was previously used in human medicine for over 10 years (1985-1995). It was generally well tolerated, with the majority of adverse effects being mild,...
Approved
Vet approved
Withdrawn
Matched Synonyms: … 2-(6-Chloro-9H-carbazol-2-yl)-propionic acid ... (±)-6-chloro-α-methylcarbazole-2-acetic acid ... (+/-)-2-(3-chloro-9H-carbazol-7-yl)propanoic acid …
Matched Iupac: … 2-(6-chloro-9H-carbazol-2-yl)propanoic acid …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... Selective Cyclooxygenase 2 Inhibitors (NSAIDs) …
Telmisartan is an angiotensin II receptor antagonist (ARB) used in the management of hypertension. Generally, angiotensin II receptor blockers (ARBs) such as telmisartan bind to the angiotensin II type 1 (AT1) receptors with high affinity, causing inhibition of the action of angiotensin II on vascular smooth muscle, ultimately leading to...
Approved
Investigational
Matched Synonyms: … 4'-((4-methyl-6-(1-methyl-2-benzimidazolyl)-2-propyl-1-benzimidazolyl)methyl)-2-biphenylcarboxylic acid ... 4'-((1,4'-dimethyl-2'-propyl(2,6'-bi-1H-benzimidazol)-1'-yl)methyl)-(1,1'-biphenyl)-2-carboxylic acid ... 4'-[(1,7'-dimethyl-2'-propyl-1H,3'H-2,5'-bibenzimidazol-3'-yl)methyl]biphenyl-2-carboxylic acid …
Matched Iupac: … ]-2-carboxylic acid ... 4'-{[4-methyl-6-(1-methyl-1H-1,3-benzodiazol-2-yl)-2-propyl-1H-1,3-benzodiazol-1-yl]methyl}-[1,1'-biphenyl …
Matched Categories: … Angiotensin 2 Receptor Blocker ... Heterocyclic Compounds, 2-Ring ... Angiotensin II Type 2 Receptor Blockers …
Profenamine (also known as ethopropazine) is a medication derived from phenothiazine. It is primarily used as an antidyskinetic to treat Parkinsonism. It is sold under the trade name Parsitan in Canada. In the US, the marketing of profenamine has been discontinued.
Approved
Matched Synonyms: … 10-[2-(diethylamino)-2-methylethyl]phenothiazine ... 10-(2-diethylaminopropyl)phenothiazine ... 10-[2-(diethylamino)propyl]phenothiazine …
Matched Iupac: … diethyl[1-(10H-phenothiazin-10-yl)propan-2-yl]amine …
Matched Salts cas: … 1094-08-2
Amikacin is a semi-synthetic aminoglycoside antibiotic that is derived from kanamycin A.[FDA label] Amikacin is synthesized by acylation with the l-(-)-γ-amino-α-hydroxybutyryl side chain at the C-1 amino group of the deoxystreptamine moiety of kanamycin A. Amikacin's unique property is that it exerts activity against more resistant gram-negative bacilli such as...
Approved
Investigational
Vet approved
Matched Synonyms: … -D-GLUCOPYRANOSYL-(1->4))-N(SUP 1)-(4-AMINO-2-HYDROXY-1-OXOBUTYL)-2-DEOXY-, (S)- ... -D-GLUCOPYRANOSYL-(1->6))-N(SUP 3)-(4-AMINO-L-2-HYDROXYBUTYRYL)-2-DEOXY-L-STREPTAMINE …
Matched Iupac: … ]-2-hydroxybutanamide ... oxan-2-yl]oxy}-4-{[(2R,3R,4S,5S,6R)-6-(aminomethyl)-3,4,5-trihydroxyoxan-2-yl]oxy}-3-hydroxycyclohexyl ... (2S)-4-amino-N-[(1R,2S,3S,4R,5S)-5-amino-2-{[(2S,3R,4S,5S,6R)-4-amino-3,5-dihydroxy-6-(hydroxymethyl) …
Matched Products: … AMIKACINA 100 MG/2 ML ... AMIKACINA 100 MG / 2 ML ... AMIKACINA 50 MG/ ML X 2 ML …
Displaying drugs 51 - 75 of 11729 in total