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Displaying drugs 51 - 75 of 161 in total

Lifitegrast

Lifitegrast is a FDA approved drug for the treatment of keratoconjunctivitis sicca (dry eye syndrome). It is a tetrahydroisoquinoline derivative and lymphocyte function-associated antigen-1 ( LFA-1) antagonist that was discovered through the rational design process. The ophthalmic solution was approved in July, 2016 under the trade name Xiidra. It has...
Approved
Matched Description: … onset of action and well tolerated profile in both local and systemic setting [A18805]. ... It is a tetrahydroisoquinoline derivative and lymphocyte function-associated antigen-1 ( LFA-1) antagonist ... It has shown to protect the corneal surface and alleviate the symptoms of dry eye syndrome with fast …
Matched Salts name: … Lifitegrast sodium …
Matched Categories: … Amino Acids, Peptides, and Proteins …

Levetiracetam

Levetiracetam is a drug within the pyrrolidine class that is used to treat various types of seizures stemming from epileptic disorders. It was first approved for use in the United States in 1999 and is structurally and mechanistically unrelated to other anti-epileptic drugs (AEDs).[L8606,L8600,L8615] Levetiracetam possesses a wide therapeutic index[L8615,A185918]...
Approved
Matched Description: … It was first approved for use in the United States in 1999 and is structurally and mechanistically unrelated ... [L8606,L8600,L8615] Levetiracetam possesses a wide therapeutic index[L8615,A185918] and little-to-no ... choice over other AEDs, a class of drugs notorious for having generally narrow therapeutic indexes and …
Matched Products: … Levetiracetam in Sodium Chloride …

Potassium gluconate

Potassium gluconate is a salt of DB01345 and is classified as a food additive by the FDA . It is also used as a potassium supplement . Potassium is an essential nutrient. It is the most abundant cation in the intracellular fluid, where it plays a key role in maintaining...
Approved
Matched Synonyms: … Potassium gluconate ... potassium D-gluconate …
Matched Name: … Potassium gluconate …
Matched Iupac: … potassium (2R,3S,4R,5R)-2,3,4,5,6-pentahydroxyhexanoate …
Matched Description: … Potassium gluconate is believed to be more palatable and non-acidifying than potassium chloride (KCl) ... In dietary supplements, potassium is often present as potassium chloride, but many other forms—including ... Potassium gluconate is a salt of [DB01345] and is classified as a food additive by the FDA [L2654]. …
Matched Mixtures name: … Iode-potassium ... Potassium W Folic Acid Tab ... Potassium Plus Vit B Complex …
Matched Categories: … Alimentary Tract and Metabolism ... Potassium Salt ... potassium gluconate …
Matched Products: … Potassium Tab 8.3mg ... Potassium Rougier ... Potassium Tab 99mg …

Potassium nitrate

Potassium nitrate is an inorganic salt with a chemical formula of KNO3. It is a natural source of nitrate and has been used as a constituent for several different purposes, including food preservatives, fertilizers, tree stump removal, rocket propellants, and fireworks. Potassium nitrate is a common active ingredient in toothpaste,...
Approved
Matched Synonyms: … Potassium nitrate …
Matched Name: … Potassium nitrate …
Matched Iupac: … potassium nitrate …
Matched Description: … In addition, potassium nitrate is used as a diuretic in pigs, cattle, and horses. ... Potassium nitrate is an inorganic salt with a chemical formula of KNO3. ... It is a natural source of nitrate and has been used as a constituent for several different purposes, …
Matched Mixtures name: … Sodium Fluoride and Potassium Nitrate ... Silver Nitrate Potassium Nitrate ... Sodium Fluoride 5000 ppm Sensitive …
Matched Categories: … Potassium Salt …
Matched Products: … Schmidts WONDERMINT TOOTH AND MOUTH ... SprinJene Natural Sensitivity and Gum …

Sodium bicarbonate

Sodium bicarbonate is a white, crystalline powder that is commonly used as a pH buffering agent, an electrolyte replenisher, systemic alkalizer and in topical cleansing solutions.
Approved
Matched Synonyms: … Sodium bicarbonate ... Sodium acid carbonate ... Sodium hydrogencarbonate …
Matched Name: … Sodium bicarbonate …
Matched Iupac: … sodium hydrogen carbonate …
Matched Description: … replenisher, systemic alkalizer and in topical cleansing solutions. ... Sodium bicarbonate is a white, crystalline powder that is commonly used as a pH buffering agent, an electrolyte …
Matched Mixtures name: … Polyethylene Glycol-3350, Sodium Chloride, Potassium Chloride and Sodium Bicarbonate ... PEG-3350, sodium chloride, sodium bicarbonate and potassium chloride ... PEG-3350, sodium chloride, sodium bicarbonate and potassium chloride …
Matched Categories: … Sodium Compounds ... Antacids and Adsorbents ... sodium bicarbonate ... sodium bicarbonate ... Blood and Blood Forming Organs …
Matched Products: … Arm and Hammer Baking Soda ... Sodium Bicarbonate ... Sodium Bicarbonate 5 gr …

Sodium phosphate, dibasic

Approved
Matched Synonyms: … Sodium phosphate dibasic ... Sodium phosphate, dibasic ... Dibasic sodium phosphate anhydrous …
Matched Name: … Sodium phosphate, dibasic …
Matched Mixtures name: … Heparin Sodium In 0.9% Sodium Chloride Injection ... Dibasic Sodium Phosphate, Monobasic Potassium Phosphate and Monobasic Sodium Phosphate ... Dibasic Sodium Phosphate, Monobasic Potassium Phosphate and Monobasic Sodium Phosphate …
Matched Salts name: … Sodium phosphate, dibasic dihydrate ... Sodium phosphate, dibasic dodecahydrate ... Sodium phosphate, dibasic, heptahydrate ... Sodium phosphate, dibasic, monohydrate …

Sodium chloride

Sodium chloride, also known as salt, common salt, table salt or halite, is an ionic compound with the chemical formula NaCl, representing a 1:1 ratio of sodium and chloride ions. Sodium chloride is the primary salt in seawater and in the extracellular fluid of many multicellular organisms. It is listed...
Approved
Vet approved
Matched Synonyms: … Sodium chloride …
Matched Name: … Sodium chloride …
Matched Iupac: … sodium chloride …
Matched Description: … chemical formula NaCl, representing a 1:1 ratio of sodium and chloride ions. ... Sodium chloride is the primary salt in seawater and in the extracellular fluid of many multicellular ... Sodium chloride, also known as salt, common salt, table salt or halite, is an ionic compound with the …
Matched Mixtures name: … Potassium Chloride in Dextrose and Sodium Chloride ... Potassium Chloride in Dextrose and Sodium Chloride ... Potassium Chloride in Dextrose and Sodium Chloride …
Matched Categories: … sodium chloride ... sodium chloride ... sodium chloride ... Alimentary Tract and Metabolism ... Blood and Blood Forming Organs …
Matched Products: … Walgreens Infants and Childrens Saline Nasal ... Sodium Chloride ... Sodium chloride …

Calcium gluconate

Calcium gluconate is used as mineral supplement and medication when there is insufficient calcium in the diet. Supplementation may be done to treat or prevent osteoporosis or rickets, consequences of hypocalcemia. It can also be taken by mouth but is not recommended by injection into a muscle. Calcium Gluconate Injection,...
Approved
Vet approved
Matched Description: … Hydrochloric acid and/or sodium hydroxide may have been added for pH adjustment (6.0 to 8.2). ... Calcium gluconate is used as mineral supplement and medication when there is insufficient calcium in ... Calcium saccharate provides 6% of the total calcium and stabilizes the supersaturated solution of calcium …
Matched Categories: … Alimentary Tract and Metabolism …
Matched Products: … Calcium Gluconate in Sodium Chloride ... 2% Calcium Gluconate In Sodium Chloride Injection …

D-glucose

Glucose is a simple sugar (monosaccharide) generated during phosynthesis involving water, carbon and sunlight in plants. It is produced in humans via hepatic gluconeogenesis and breakdown of polymeric glucose forms (glycogenolysis). It circulates in human circulation as blood glucose and acts as an essential energy source for many organisms through...
Approved
Investigational
Vet approved
Matched Description: … through aerobic or anaerobic respiration and fermentation. ... Glucose is a simple sugar (monosaccharide) generated during phosynthesis involving water, carbon and ... L-glucose is a synthesized enantiomer that is used as a low-calorie sweetener and laxative. …
Matched Mixtures name: … Potassium Chloride in Dextrose and Sodium Chloride ... Potassium Chloride in Dextrose and Sodium Chloride ... Potassium Chloride in Dextrose and Sodium Chloride …
Matched Categories: … Diet, Food, and Nutrition …

Docusate

Docusate, or dioctyl sulfosuccinate, is a stool softener indicated for the treatment of constipation . Docusate acts by increasing the amount of water the stool absorbs in the gut, making the stool softer and easier to pass . Docusate can be orally or rectally administered. Docusate is on the World...
Approved
Matched Description: … Docusate acts by increasing the amount of water the stool absorbs in the gut, making the stool softer and …
Matched Mixtures name: … Senna and Docusate Sodium ... Senna and Docusate Sodium ... Docusate Sodium and Senna …
Matched Salts name: … Docusate sodium ... Docusate potassium …
Matched Categories: … Alimentary Tract and Metabolism ... Softener and Emollient Laxatives …
Matched Products: … Up and up stool softener ... Stool Softener easy and gentle ... Docusate Sodium …

Cyclothiazide

As a diuretic, cyclothiazide inhibits active chloride reabsorption at the early distal tubule via the Na-Cl cotransporter, resulting in an increase in the excretion of sodium, chloride, and water. Thiazides like cyclothiazide also inhibit sodium ion transport across the renal tubular epithelium through binding to the thiazide sensitive sodium-chloride transporter....
Approved
Matched Description: … Na-Cl cotransporter, resulting in an increase in the excretion of sodium, chloride, and water. ... This results in an increase in potassium excretion via the sodium-potassium exchange mechanism. ... binding to the thiazide sensitive sodium-chloride transporter. …
Matched Categories: … cyclothiazide and potassium ... Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics …

Bumetanide

Bumetanide is a sulfamyl diuretic.
Approved
Matched Categories: … Sodium Potassium Chloride Symporter Inhibitors ... bumetanide and potassium ... bumetanide and potassium-sparing agents ... High-Ceiling Diuretics and Potassium-Sparing Agents ... Non Potassium Sparing Diuretics …

Dyclonine

Dyclonine is an oral anaesthetic found in Sucrets, an over the counter throat lozenge. It may also be found in some Cepacol sore throat spray products.
Approved
Matched Mixtures name: … Benzethonium Chloride and Dyclonine Hydrochloride ... Benzethonium chloride and Dyclonine hydrochloride ... Benzethonium Chloride and Dyclonine Hydrochloride …

Phenobarbital

A barbituric acid derivative that acts as a nonselective central nervous system depressant. It promotes binding to inhibitory gamma-aminobutyric acid subtype receptors, and modulates chloride currents through receptor channels. It also inhibits glutamate induced depolarizations.
Approved
Investigational
Matched Description: … It promotes binding to inhibitory gamma-aminobutyric acid subtype receptors, and modulates chloride currents …
Matched Mixtures name: … Phenobarbital, Hyoscyamine Sulfate, Atropine Sulfate and Scopolamine Hydrobromide ... Phenobarbital, Hyoscyamine Sulfate, Atropine Sulfate and Scopolamine Hydrobromide …
Matched Salts name: … Phenobarbital sodium …
Matched Categories: … Barbiturates and Derivatives ... Hypnotics and Sedatives ... Phenobarbital and similars ... Metabolic Side Effects of Drugs and Substances …
Matched Products: … Phenobarbital Sodium ... PHENOBARBITAL SODIUM ... Phenobarbital Sodium Injection, USP …

Micafungin

Micafungin is an antifungal drug. It belongs to the antifungal class of compounds known as echinocandins and exerts its effect by inhibiting the synthesis of 1,3-beta-D-glucan, an integral component of the fungal cell wall.
Approved
Investigational
Matched Description: … It belongs to the antifungal class of compounds known as echinocandins and exerts its effect by inhibiting …
Matched Salts name: … Micafungin sodium …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Products: … Micafungin in Sodium Chloride ... Micafungin Sodium for Injection …

Polythiazide

A thiazide diuretic with actions and uses similar to those of hydrochlorothiazide. (From Martindale, The Extra Pharmacopoeia, 30th ed, p826)
Approved
Matched Description: … A thiazide diuretic with actions and uses similar to those of hydrochlorothiazide. …
Matched Categories: … Sodium Chloride Symporter Inhibitors ... polythiazide and potassium ... Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics …

Lubiprostone

Lubiprostone is a medication used in the management of idiopathic chronic constipation. A prostaglandin E1 derivative, lubiprostone is a bicyclic fatty acid that activates ClC-2 chloride channels located on the apical side of the gastrointestinal epithelial cells. Activation of these channels promotes the secretion of a chloride-rich fluid that soften...
Approved
Investigational
Matched Description: … gastrointestinal motility, and induce spontaneous bowel movements (SBM). ... A prostaglandin E1 derivative, lubiprostone is a bicyclic fatty acid that activates ClC-2 chloride channels ... Activation of these channels promotes the secretion of a chloride-rich fluid that soften the stool, increase …
Matched Categories: … Chloride Channel Agonists ... Alimentary Tract and Metabolism …

Benzocaine

Benzocaine is an ester local anesthetic that acts by preventing transmission of impulses along nerve fibers and at nerve endings. It is commonly used for local anesthesia in many over the counter products.[L32454,L32459,L32464] Benzocaine was first used for local anesthesia in dentistry.
Approved
Investigational
Matched Description: … Benzocaine is an ester local anesthetic that acts by preventing transmission of impulses along nerve fibers and …
Matched Mixtures name: … Benzocaine, Menthol, Zinc Chloride ... Benzocaine, Menthol, Zinc Chloride ... Benzocaine, Menthol, Zinc Chloride …
Matched Categories: … Antipruritics and Local Anesthetics ... Agents for Treatment of Hemorrhoids and Anal Fissures for Topical Use …
Matched Products: … Sting and Bite ... Bite and Sting relief ... Medicaine Sting and Bite …

Cyclopenthiazide

Cyclopenthiazide is a thiazide diuretic with antihypertensive properties. In a double blind, randomized crossover study, cyclopenthiazide was effective in reducing diastolic blood pressure in mildly hypertensive non-insulin dependent diabetic patients . It is a positive allosteric modulator at AMPA-A receptors .
Approved
Matched Categories: … Sodium Chloride Symporter Inhibitors ... cyclopenthiazide and potassium ... cyclopenthiazide and potassium-sparing agents ... Low-Ceiling Diuretics and Potassium-Sparing Agents ... Genito Urinary System and Sex Hormones …

Tobramycin

Aminoglycosides, many of which are derived directly from Streptomyces spp., are concentration-dependent bactericidal antibiotics with a broad spectrum of activity against Gram-positive and Gram-negative organisms. Inhaled tobramycin is notable for its use in treating chronic Pseudomonas aeruginosa infections in cystic fibrosis patients, as P. aeruginosa is notoriously inherently resistant to...
Approved
Investigational
Matched Description: … concentration-dependent bactericidal antibiotics with a broad spectrum of activity against Gram-positive and ... [A232294, A232299, L32739] However, tobramycin can also be administered intravenously and topically to ... L32744, L32749] Its use is limited in some cases by characteristic toxicities such as nephrotoxicity and …
Matched Mixtures name: … Tobramycin and Dexamethasone ... Tobramycin and Dexamethasone ... Tobramycin and Dexamethasone …
Matched Products: … Tobramycin in Sodium Chloride …

Chloramphenicol succinate

Chloramphenicol succinate is an ester prodrug of chloramphenicol. Chloramphenicol is a bacteriostatic antibiotic. Use of chloramphenicol succinate and chloramphenicol has decreased due to the risk of potentially fatal blood dyscrasias. Chloramphenicol succinate was granted FDA approval on 20 February 1959.
Approved
Matched Description: … [A204065] Use of chloramphenicol succinate and chloramphenicol has decreased due to the risk of potentially …
Matched Salts name: … Chloramphenicol sodium succinate …
Matched Products: … Chloromycetin Sodium Succinate ... Chloramphenicol Sodium Succinate ... CHLORAMPHENICOL SODIUM SUCCINATE …

Lumacaftor

Lumacaftor is a drug used in combination with DB08820 as the fixed dose combination product Orkambi for the management of Cystic Fibrosis (CF) in patients aged 6 years and older. Cystic Fibrosis is an autosomal recessive disorder caused by one of several different mutations in the gene for the Cystic...
Approved
Matched Description: … and sodium ions across cell membranes of the lungs, pancreas, and other organs. ... Transmembrane Conductance Regulator (CFTR) protein, a transmembrane ion channel involved in the transport of chloride ... Approved for use by the Food and Drug Administration in July 2015 and by Health Canada in January 2016 …
Matched Categories: … ivacaftor and lumacaftor …

Tranexamic acid

Tranexamic acid is a synthetic derivative of lysine used as an antifibrinolytic in the treatment and prevention of major bleeding. It possesses a similar mechanism of action to aminocaproic acid but is approximately 10-fold more potent. It was first patented in 1957 and received its initial US approval in 1986.
Approved
Matched Description: … Tranexamic acid is a synthetic derivative of [lysine] used as an antifibrinolytic in the treatment and ... [L31883] It was first patented in 1957[A230108] and received its initial US approval in 1986. …
Matched Categories: … Blood and Blood Forming Organs ... Amino Acids, Peptides, and Proteins …
Matched Products: … Tranexamic Acid In Sodium Chloride …

Midazolam

Midazolam is a short-acting hypnotic-sedative drug with anxiolytic, muscle relaxant, anticonvulsant, sedative, hypnotic, and amnesic properties. It belongs to a class of drugs called benzodiazepines. This drug is unique from others in this class due to its rapid onset of effects and short duration of action. Midazolam is available by...
Approved
Illicit
Matched Description: … and endoscopic procedures as pre-anesthetic medication, and as an adjunct to local anesthesia. ... This drug is unique from others in this class due to its rapid onset of effects and short duration of ... short-acting hypnotic-sedative drug with anxiolytic, muscle relaxant, anticonvulsant, sedative, hypnotic, and …
Matched Categories: … Hypnotics and Sedatives ... Benzodiazepine hypnotics and sedatives ... Benzodiazepines and benzodiazepine derivatives …
Matched Products: … Midazolam in Sodium Chloride …

Bromotheophylline

Bromotheophylline is the active moiety of pamabrom, a mixture of 2-amino-2-methyl-propanol and bromotheophylline. From this mixture, bromotheophylline acts as a weak diuretic that has been used along with some analgesics to relieve the symptoms of premenstrual syndrome. Bromotheophylline is categorized on the FDA as a drug substance with an inactive...
Approved
Matched Description: … Bromotheophylline is the active moiety of pamabrom, a mixture of 2-amino-2-methyl-propanol and bromotheophylline …
Displaying drugs 51 - 75 of 161 in total