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Displaying drugs 51 - 75 of 8037 in total

Zinc sulfate, unspecified form

Zinc sulfate is a common zinc supplement in parenteral nutrition.[A216916,L12888]
Approved
Experimental
Matched Categories: … Agents for Treatment of Hemorrhoids and Anal Fissures for Topical Use …

Nutmeg

Nutmeg allergenic extract is used in allergenic testing.
Approved
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …

Lomifylline

Approved
Matched Categories: … combinations of xanthines …

Clodronic acid

Clodronic acid is a first generation bisphosphonate similar to etidronic acid and tiludronic acid. These drugs were developed to mimic the action of pyrophosphate, a regulator of calcification and decalcification. clodronate’s use has decreased over the years in favor of the third generation, nitrogen containing bisphosphonate zoledronic acid, ibandronic acid,...
Approved
Investigational
Vet approved
Matched Description: … [A203111] These drugs were developed to mimic the action of pyrophosphate, a regulator of calcification ... [A1923] clodronate’s use has decreased over the years in favor of the third generation, nitrogen containing …
Matched Categories: … Drugs for Treatment of Bone Diseases …

Gadolinium

Gadolinium is under investigation in Hypertension, ACUTE KIDNEY INJURY, and Chronic Kidney Disease. Gadolinium has been investigated for the basic science of CAD, Multiple Sclerosis, and Coronary Artery Disease.
Approved
Investigational
Matched Description: … Gadolinium has been investigated for the basic science of CAD, Multiple Sclerosis, and Coronary Artery …
Matched Categories: … Diagnostic Uses of Chemicals …

Triamcinolone

Triamcinolone is a corticosteroid used to treat various inflammatory conditions in the body from allergic rhinitis to acute exacerbations of multiple sclerosis. Triamcinolone can be used as a one time adjunct treatment of osteoarthritic knee pain, or first line as a topical treatment of corticosteroid responsive dermatoses. Triamcinolone is more...
Approved
Vet approved
Matched Description: … or first line as a topical treatment of corticosteroid responsive dermatoses. ... to treat various inflammatory conditions in the body from allergic rhinitis to acute exacerbations of ... [L8255] Triamcinolone can be used as a one time adjunct treatment of osteoarthritic knee pain,[L8264] …
Matched Mixtures name: … Point Of Care Kit KM …

Lanthanum carbonate

Lanthanum carbonate is a phosphate binder marketed under the trade name Fosrenol by Shire Pharmaceuticals. It is a large pill that requires thorough chewing to avoid choking and other gastrointestinal adverse effects. It is used to treat elevated phosphate levels, primarily in patients with chronic kidney disease, by binding to...
Approved
Matched Categories: … Drugs for Treatment of Hyperkalemia and Hyperphosphatemia …

Omadacycline

Omadacycline has been used in trials studying the treatment of Bacterial Pneumonia, Bacterial Infections, Community-Acquired Infections, and Skin Structures and Soft Tissue Infections. Omadacycline represents a significant advance over the well-known tetracycline family, and has been shown to be highly effective in animal models at treating increasingly problematic, clinically prevalent...
Approved
Investigational
Matched Description: … Omadacycline has been used in trials studying the treatment of Bacterial Pneumonia, Bacterial Infections ... gram-negative, atypical and anaerobic bacteria, including those resistant to currently available classes of …
Matched Categories: … combinations of tetracyclines …

Cefixime

Bacteria possess a cell wall comprising a glycopeptide polymer commonly known as peptidoglycan, which is synthesized and remodelled through the action of a family of enzymes known as "penicillin-binding proteins" (PBPs). β-lactam antibiotics, including cephalosporins, are PBP inhibitors that, through inhibition of essential PBPs, result in impaired cell wall homeostasis,...
Approved
Investigational
Matched Description: … a family of enzymes known as "penicillin-binding proteins" (PBPs). ... A232920] β-lactam antibiotics, including cephalosporins, are PBP inhibitors that, through inhibition of ... glycopeptide polymer commonly known as peptidoglycan, which is synthesized and remodelled through the action of …

Trypsin

Trypsin is a serine protease that plays an essential role in protein hydrolysis and absorption in mammals. When converted from its zymogen trypsinogen, trypsin is available as an active peptide hydrolase (EC 3.4.21.4) form to cleave peptide chains, mainly at the carboxyl side of the amino acids lysine or arginine....
Approved
Vet approved
Matched Description: … Therapeutic forms of trypsin is obtained from purified extracts of porcine or bovine pancreas and is ... an active peptide hydrolase (EC 3.4.21.4) form to cleave peptide chains, mainly at the carboxyl side of ... This nucleophilic attack is facilitated by the catalytic triad consisting of histidine-57, aspartate- …
Matched Categories: … Preparations for Treatment of Wounds and Ulcers …

Perflubutane

Perflubutane has been used in trials studying the diagnostic of Liver Mass, Liver Diseases, Liver Metastasis, Portal Hypertension, and Peripheral Artery Disease. It is a cardiovascular drug designed to enable ultrasound to compete more effectively with nuclear stress testing; currently the leading procedure for detecting coronary heart disease.
Approved
Investigational
Matched Description: … Perflubutane has been used in trials studying the diagnostic of Liver Mass, Liver Diseases, Liver Metastasis …
Matched Categories: … Diagnostic Uses of Chemicals …

Strontium ranelate

Strontium ranelate, a strontium (II) salt of ranelic acid, is a medication for osteoporosis. Some reports have shown that strontium ranelate can slow down the progression of osteoarthritis of the knee. This agent presents an atypical mechanism of action in which it increases deposition of new bone by osteoblasts and,...
Approved
Withdrawn
Matched Description: … Some reports have shown that strontium ranelate can slow down the progression of osteoarthritis of the ... intrinsic bone tissue quality and microarchitecture in osteoporosis by way of a number of cellular and ... This agent presents an atypical mechanism of action in which it increases deposition of new bone by osteoblasts …
Matched Categories: … Drugs for Treatment of Bone Diseases …

Technetium Tc-99m pertechnetate

Technetium Tc-99m pertechnetate is a radiopharmaceutical diagnostic agent composed of an oxoanion with the chemical formula TcO4-. Pertechnetate has a wide variety of uses within nuclear medicine as it distributes within the body to a similar extent as iodine. It also concentrates in the thyroid gland, salivary glands, gastric mucosa,...
Approved
Investigational
Matched Description: … Technetium Tc-99m pertechnetate is a radiopharmaceutical diagnostic agent composed of an oxoanion with ... Pertechnetate has a wide variety of uses within nuclear medicine as it distributes within the body to ... Currently marketed as the product Drytec, technetium-99m pertechnetate is indicated for imaging of the …
Matched Categories: … Diagnostic Uses of Chemicals …

Pantothenic acid

Pantothenic acid, also called pantothenate or vitamin B5 (a B vitamin), is a water-soluble vitamin discovered by Roger J. Williams in 1919. For many animals, pantothenic acid is an essential nutrient as it is required to synthesize coenzyme-A (CoA), as well as to synthesize and metabolize proteins, carbohydrates, and fats....
Approved
Nutraceutical
Vet approved
Matched Description: … (L) form may antagonize the effects of the dextrorotatory isomer. ... Small quantities of pantothenic acid are found in nearly every food, with high amounts in whole-grain ... Only the dextrorotatory (D) isomer of pantothenic acid possesses biological activity. while the levorotatory …
Matched Mixtures name: … Herbs of Gold B Complex Plus Softgel ... Harvest Of Values All B Complex Tab …
Matched Categories: … Preparations for Treatment of Wounds and Ulcers …

Gadobutrol

Gadobutrol is a second-generation extracellular non-ionic macrocyclic GBCA (gadolinium-based contrast agent) used in magnetic resonance imaging (MRI) in adults and children older than 2 years of age. Due to its physicochemical properties, gadobutrol is formulated at twice the gadolinium ion concentration compared to other GBCA and thus requires a lesser...
Approved
Matched Description: … of NSF thanks to the macrocyclic structures that limit dechelation of gadolinium. ... contrast agent) used in magnetic resonance imaging (MRI) in adults and children older than 2 years of ... [A7001] Like other GBCA, gadobutrol usage carries the risk of nephrogenic systemic fibrosis (NSF) …
Matched Categories: … Diagnostic Uses of Chemicals …

Latanoprost

Latanoprost is a prodrug analog of prostaglandin F2 alpha that is used to treat elevated intraocular pressure (IOP). It was initially approved by the FDA in 1998. Latanoprost is the first topical prostaglandin F2 alpha analog used for glaucoma treatment. It has been found to be well-tolerated and its use...
Approved
Investigational
Matched Description: … Latanoprost is a prodrug analog of prostaglandin F2 alpha that is used to treat elevated intraocular …

Lasofoxifene

Lasofoxifene is a non-steroidal 3rd generation selective estrogen receptor modulator (SERM) that selectively binds to both ERα and ERβ with high affinity. It is a naphthalene derivative marketed for prevention and treatment of osteoporosis and for the treatment of vaginal atrophy. It was initially developed as Oporia by Pfizer as...
Approved
Investigational
Matched Description: … of vaginal atrophy. ... It is a naphthalene derivative marketed for prevention and treatment of osteoporosis and for the treatment ... signed a license agreement with Sermonix Pharmaceuticals for the development and commercialization of …
Matched Categories: … Sex Hormones and Modulators of the Genital System …

Technetium Tc-99m tetrofosmin

Technetium Tc-99m tetrofosmin is a drug used in nuclear myocardial perfusion imaging. The radioisotope, technetium-99m, is chelated by two 1,2-bis[di-(2-ethoxyethyl)phosphino]ethane ligands which belong to the group of diphosphines and which are referred to as tetrofosmin. It is a lipophilic technetium phosphine dioxo cation that was formulated into a freeze-dried kit...
Approved
Matched Description: … 99m, is chelated by two 1,2-bis[di-(2-ethoxyethyl)phosphino]ethane ligands which belong to the group of …
Matched Categories: … Diagnostic Uses of Chemicals …

Cyclacillin

A cyclohexylamido analog of penicillanic acid.
Approved
Matched Description: … A cyclohexylamido analog of penicillanic acid. …
Matched Categories: … combinations of penicillins …

Meglumine

Approved
Matched Categories: … Diagnostic Uses of Chemicals …

Gadoversetamide

Gadoversetamide, marketed under the trade name OptiMARK, is a gadolinium compound used as a contrast agent in magnetic resonance imaging (MRI), particularly imaging of the brain, spine and liver.
Approved
Investigational
Matched Description: … gadolinium compound used as a contrast agent in magnetic resonance imaging (MRI), particularly imaging of …
Matched Categories: … Diagnostic Uses of Chemicals …

Torasemide

Torasemide is a high-ceiling loop diuretic. Structurally, it is a pyridine-sulfonylurea used as an antihypertensive agent. Torasemide was first approved for clinical use by the FDA in 1993.
Approved
Matched Categories: … combinations of sulfonamides ... Increased Diuresis at Loop of Henle …

Tapentadol

Tapentadol is a centrally-acting synthetic analgesic with a dual mechanism of action. It is a mu-opioid receptor agonist that also inhibits norepinephrine reuptake.[A260721, A36596] Tapentadol was first approved by the FDA on November 20, 2008. The extended-release formulation of tapentadol was also approved by the FDA on August 26, 2011....
Approved
Matched Description: … Tapentadol is a centrally-acting synthetic analgesic with a dual mechanism of action. ... The extended-release formulation of tapentadol was also approved by the FDA on August 26, 2011. ... [L47291] Used in the management of pain, tapentadol is typically reserved for patients who have limited …
Matched Categories: … Combined Inhibitors of Serotonin/Norepinephrine Reuptake ... Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …

Tetracaine

Tetracaine is an ester local anaesthetic currently available in combination with lidocaine as a cream and patch.
Approved
Vet approved
Matched Categories: … Esters of Aminobenzoic Acid ... Agents for Treatment of Hemorrhoids and Anal Fissures for Topical Use …

Burosumab

Burosumab (KRN23) is an entirely human monoclonal IgG1 antibody that binds excess fibroblast growth factor 23 (FGF23) and has been successfully tested in clinical trials in children with X-linked hypophosphatemic rickets . The U.S. Food and Drug Administration approved Crysvita (burosumab) in April 2018. This is the first drug approved...
Approved
Investigational
Matched Description: … X-linked hypophosphatemia causes low circulating levels of phosphorus in the blood. ... children ages 1 year and older with X-linked hypophosphatemia (XLH), which is a rare, inherited form of …
Matched Categories: … Drugs for Treatment of Bone Diseases …
Displaying drugs 51 - 75 of 8037 in total