Displaying drugs 51 - 75 of 96 in total
Codeine
The relief of pain (analgesia) is a primary goal for enhancing the quality of life of patients and for increasing the ability of patients to engage in day to day activities. Codeine, an opioid analgesic, was originally approved in the US in 1950 and is a drug used to decrease...
Approved
Illicit
Matched Salts name: … Codeine phosphate hemihydrate …
Matched Products: … CODEINE PHOSPHATE HEMIHYDRATE …
Matched Products: … CODEINE PHOSPHATE HEMIHYDRATE …
Levofloxacin
Levofloxacin is a fluoroquinolone antibiotic and the optical S-(-) isomer of racemic ofloxacin. It reportedly carries 8 to 128-fold more activity against both gram-negative and gram-positive bacteria compared to R-(+)-ofloxacin and remains stereochemically stable following administration (i.e. it does not invert to the inactive isomer). Levofloxacin, along with other quinolones...
Approved
Investigational
Matched Salts name: … Levofloxacin hemihydrate …
Matched Products: … LEVOFLOXACIN HEMIHYDRATE …
Matched Products: … LEVOFLOXACIN HEMIHYDRATE …
Pentaerythritol tetranitrate
Pentaerythritol tetranitrate is the nitrate ester of pentaerythritol that possesses explosive properties. When mixed with a plasticizer, this chemical forms a plastic explosive. It is recognized by the FDA to be a coronary vasodilator in the treatment of heart conditions such as angina .
It is a pentaerythritol nitrate in...
Approved
Matched Iupac: … 3-(nitrooxy)-2,2-bis[(nitrooxy)methyl]propyl nitrate …
Matched Description: … to the corresponding nitrate ester. ... Pentaerythritol tetranitrate is the nitrate ester of pentaerythritol that possesses explosive properties ... It is a pentaerythritol nitrate in which all four hydroxy groups of pentaerythritol have been converted …
Matched Description: … to the corresponding nitrate ester. ... Pentaerythritol tetranitrate is the nitrate ester of pentaerythritol that possesses explosive properties ... It is a pentaerythritol nitrate in which all four hydroxy groups of pentaerythritol have been converted …
Butoconazole
Butoconazole is an imidazole antifungal used in gynecology.
Approved
Matched Salts name: … Butoconazole nitrate …
Dipyridamole
A phosphodiesterase inhibitor that blocks uptake and metabolism of adenosine by erythrocytes and vascular endothelial cells. Dipyridamole also potentiates the antiaggregating action of prostacyclin. (From AMA Drug Evaluations Annual, 1994, p752)
Approved
Nitrous acid
Nitrous acid (as sodium nitrite) is used as part of an intravenous mixture with sodium thiosulfate to treat cyanide poisoning. It is on the World Health Organization's List of Essential Medicines, a list of the most important medications needed in a basic health system. There is also research to investigate...
Approved
Investigational
Nitric Oxide
Nitric oxide or Nitrogen monoxide is a chemical compound with chemical formula NO. This gas is an important signaling molecule in the body of mammals including humans and is an extremely important intermediate in the chemical industry. It is also a toxic air pollutant produced by automobile engines and power...
Approved
Berdazimer
Berdazimer is a polymeric substance consisting of a polysiloxane backbone (Si-O-Si bonds) with covalently bound N-diazeniumdiolate nitric oxide (NO) donors. It releases NO through exposure to proton donors like water, which will degrade the N-diazeniumdiolate entity. Berdazimer was previously investigated as a potential treatment for molluscum contagiosum, a viral cutaneous...
Approved
Copper Cu-64
Copper-64 is a radiopharmaceutical usually found in the +2 oxidation state as the complexes including the +1 state tend to be more unstable. It is used in molecular radiotherapy and positron emission tomography.
Approved
Matched Salts name: … Cupric chloride anhydrous Cu-64 …
Canagliflozin
Canagliflozin, also known as Invokana, is a sodium-glucose cotransporter 2 (SGLT2) inhibitor used in the management of type 2 diabetes mellitus along with lifestyle changes including diet and exercise [FDA label].
It was initially approved by the FDA in 2013 for the management of diabetes and later approved in 2018...
Approved
Silver sulfadiazine
Silver sulfadiazine is a sulfa derivative topical antibacterial used primarily on second- and third-degree burns.
Approved
Vet approved
Estradiol
Estradiol is a naturally occurring hormone circulating endogenously in females. It is commercially available in several hormone therapy products for managing conditions associated with reduced estrogen, such as vulvovaginal atrophy and hot flashes. Some available forms of estradiol include oral tablets, injections, vaginal rings, transdermal patches, sprays, gels, and creams.[L11485,L11488,L11491,...
Approved
Investigational
Vet approved
Matched Salts name: … Estradiol hemihydrate …
Chromium
Chromium is a transition element with the chemical symbol Cr and atomic number 24 that belongs to Group 6 of the periodic table. It is used in various chemical, industrial and manufacturing applications such as wood preservation and metallurgy. The uses of chromium compounds depend on the valency of chromium,...
Approved
Naphazoline
Naphazoline is a rapid acting imidazoline sympathomimetic vasoconstrictor of ocular or nasal artierioles[L5804,L5807]. It acts to decrease congestion and is found in many over the counter (OTC) eye drops and nasal preparations[L5804,L5807].
Naphazoline was first developed in 1942 as a nasal formulation for congestion .
Approved
Investigational
Matched Salts name: … Naphazoline nitrate …
Aluminum zirconium octachlorohydrex gly
Aluminum zirconium octachlorohydrex gly is complex that consists of aluminum zirconium octachlorohydrate and glycine. It is an active antiperspirant agent , . It diffuses into the sweat pores and prevents perspiration (sweat) from leaving the pores. The anhydrous form of the compound also has water-absorbing properties. Currently, the FDA allows...
Approved
Procaine
A local anesthetic of the ester type that has a slow onset and a short duration of action. It is mainly used for infiltration anesthesia, peripheral nerve block, and spinal block. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1016). Procaine has also been investigated as an oral entry inhibitor in...
Approved
Investigational
Vet approved
Matched Salts name: … Procaine nitrate …
Sodium fluoride
Sodium fluoride is an inorganic chemical compound that is a source of the fluoride ion in many applications, including dental care and radiographic imaging when it is used as Fluoride ion F-18. Sodium fluoride's benefits on dental health were first observed in the 1930s, when individuals in communities with fluoridated...
Approved
Matched Mixtures name: … Sodium Fluoride and Potassium Nitrate …
Cefadroxil
Long-acting, broad-spectrum, water-soluble, cephalexin derivative.
Approved
Vet approved
Withdrawn
Matched Salts name: … Cefadroxil hemihydrate …
Doxycycline
Doxycycline is a broad-spectrum antibiotic synthetically derived from oxytetracycline. It is a second-generation tetracycline that was first discovered in 1967. Second-generation tetracyclines exhibit lesser toxicity than first-generation tetracyclines. Doxycycline is used to treat a wide variety of gram-positive and gram-negative bacterial infections. It is also used to treat acne and...
Approved
Investigational
Vet approved
Sitagliptin
Sitagliptin is an oral dipeptidyl peptidase-4 (DPP-4) inhibitor used in conjunction with diet and exercise to improve glycemic control in patients with type 2 diabetes mellitus[FDA label,A2260,A2255,A2256]. The effect of this medication leads to glucose dependent increases in insulin and decreases in glucagon to improve control of blood sugar[FDA label,A2255]....
Approved
Investigational
Matched Salts name: … Sitagliptin tartrate hemihydrate …
Nitrate
Experimental
Investigational
Matched Synonyms: … Nitrate ion …
Matched Name: … Nitrate …
Matched Iupac: … nitrate …
Matched Name: … Nitrate …
Matched Iupac: … nitrate …
Aminoethyl nitrate
Experimental
Matched Synonyms: … Aminoethyl nitrate ... 2-aminoethyl nitrate …
Matched Name: … Aminoethyl nitrate …
Matched Iupac: … 2-aminoethyl nitrate …
Matched Name: … Aminoethyl nitrate …
Matched Iupac: … 2-aminoethyl nitrate …
Cupric glycinate
Vet approved
Matched Synonyms: … Cupric glycinate ... Cupric aminoacetate …
Matched Name: … Cupric glycinate …
Matched Name: … Cupric glycinate …
Propatyl nitrate
Experimental
Investigational
Matched Synonyms: … Propatyl nitrate …
Matched Name: … Propatyl nitrate …
Matched Name: … Propatyl nitrate …
Displaying drugs 51 - 75 of 96 in total