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Displaying drugs 76 - 100 of 154 in total

Lotilaner

Lotilaner is an ectoparasiticide that is a member of the isoxazoline family of compounds. Lotilaner has largely been used for veterinary uses as an antiparasitic agent to treat flea and tick infestations in animals.[A260746, L47556] Lotilaner consists of two enantiomers: the S-enantiomer is active in vivo, while the R-enantiomer is...
Approved
Vet approved

Cromoglicic acid

A chromone complex that acts by inhibiting the release of chemical mediators from sensitized mast cells. It is used in the prophylactic treatment of both allergic and exercise-induced asthma, but does not affect an established asthmatic attack.
Approved

Polyethylene glycol 300

Polyethylene glycol 300 (PEG 300) is a water-miscible polyether with an average molecular weight of 300 g/mol. It is a clear viscous liquid at room temperature with non-volatile, stable properties . Polyethylene glycols are widely used in biochemistry, structural biology, and medicine in addition to pharmaceutical and chemical industries. They...
Approved

Polymyxin B

Polymyxin B was discovered in the 1940s . They are basic polypeptides of about eight amino acids and have cationic detergent action on cell membranes . Polymyxin B is used for infections with gram-negative organisms, but may be neurotoxic and nephrotoxic[A176426,FDA Label]. All gram-positive bacteria, fungi, and the gram-negative cocci,...
Approved
Vet approved
Matched Mixtures name: … Cortisporin Ophthalmic ... Neo Bace Ophthalmic Ointment ... Polytrim Ophthalmic Solution …

Vidarabine

A nucleoside antibiotic isolated from Streptomyces antibioticus. It has some antineoplastic properties and has broad spectrum activity against DNA viruses in cell cultures and significant antiviral activity against infections caused by a variety of viruses such as the herpes viruses, the vaccinia VIRUS and varicella zoster virus.
Approved
Investigational

Gramicidin D

Gramcidin D is a heterogeneous mixture of three antibiotic compounds, gramicidins A, B and C, making up 80%, 6%, and 14% respectively all of which are obtained from the soil bacterial species Bacillus brevis and called collectively gramicidin D. Gramcidins are 15 residue peptides with alternating D and L amino...
Approved
Matched Description: … Gram-negative organisms, Gramicidin D is used primarily as a topical antibiotic and is also found in Polysporin ophthalmic …

Suprofen

An ibuprofen-type anti-inflammatory analgesic and antipyretic. It inhibits prostaglandin synthesis and has been proposed as an anti-arthritic. It is no longer approved for use in the United States.
Approved
Withdrawn

Polyvinyl alcohol

Polyvinyl alcohol is a water-soluble synthetic polymer obtained by polymerization of vinyl alcohol. It has varying roles in commercial and industrial applications such as papermaking, textiles, and printing. Polyvinyl alcohol is found in ophthalmic solutions as a lubricant to prevent irritation or to relieve dryness of the eyes .
Approved
Matched Description: … Polyvinyl alcohol is found in ophthalmic solutions as a lubricant to prevent irritation or to relieve …

Lodoxamide

Lodoxamide is a mast-cell stabilizer for topical administration into the eye. Mast-cell stabilizers, first one approved being cromolyn sodium, are used in treatment of ocular hypersensitivity reactions such as vernal conjunctivitis. These conditions often require treatment with anti-inflammatory medications such as ophthalmic NSAIDs or topical steroids which may cause systemic...
Approved
Matched Description: … These conditions often require treatment with anti-inflammatory medications such as ophthalmic NSAIDs …

Acyclovir

Acyclovir is a deoxynucleoside analog antiviral used to treat herpes simplex, Varicella zoster, herpes zoster, herpes labialis, and acute herpetic keratitis.[L7303,L7315,L7318,L7321,L7324,L7327] Acyclovir is generally used first line in the treatment of these viruses and some products are indicated for patients as young as 6 years old. Acyclovir was granted FDA...
Approved
Matched Products: … ZOVIRAX OPHTHALMIC OINTMENT 3% w/w …

Water

Water (chemical formula: H2O) is a transparent fluid which forms the world's streams, lakes, oceans and rain, and is the major constituent of the fluids of organisms. As a chemical compound, a water molecule contains one oxygen and two hydrogen atoms that are connected by covalent bonds. Water is a...
Approved
Matched Products: … PhysiciansCare Ophthalmic Solution Eyewash ... PhysiciansCare Ophthalmic Solution Eyewash Purified Water, 98.3% …

Epinephrine

Epinephrine, also known as adrenaline, is a hormone and neurotransmitter and produced by the adrenal glands that can also be used as a drug due to its various important functions. Though it has long been used in the treatment of hypersensitivity reactions, epinephrine in the auto-injector form (EpiPen) has been...
Approved
Vet approved
Matched Mixtures name: … E-pilo 4 Ophthalmic Solution ... E-pilo 1 Ophthalmic Solution ... E-pilo 2 Ophthalmic Solution …

Sulfacetamide

An anti-infective agent that is used topically to treat skin infections and orally for urinary tract infections.
Approved
Matched Mixtures name: … Vasocidin Ophthalmic Solution ... Vasocidin Ophthalmic Solution …

Cysteamine

Cystinosis is a rare disease caused by mutations in the CTNS gene that encodes for cystinosin, a protein responsible for transporting cystine out of the cell lysosome. A defect in cystinosin function is followed by cystine accumulation throughout the body, especially the eyes and kidneys. Several preparations of cysteamine exist...
Approved
Investigational
Matched Description: … [L15611] On August 25th 2020, the first ophthalmic solution for cystinosis requiring only 4 daily ... cysteamine exist for the treatment of cystinosis manifestations, some in capsule form, and others in ophthalmic …

Fluocinolone acetonide

Fluocinolone acetonide, with the formula 6-alpha, 9-alpha-difluoro-16-alpha, 17 alpha-acetonide, is a corticosteroid that presents a high lipophilicity. It has been used extensively in dermatological preparations and it has also been investigated thoroughly for its use in implantable corticosteroid devices. This type of device containing fluocinolone acetonide was developed by Taro...
Approved
Investigational
Vet approved

Polysorbate 20

Polysorbate 20 is a polysorbate-type nonionic surfactant used in many commercial, household and pharmaceutical products. It is composed of 20 repeated units of polyethylene glycol via ethoxylation. Polysorbate 20 is a wetting agent in food products, as well as washing agent, stabilizer and solubilizer in labratory assays and industrial applications....
Approved
Matched Description: … an excipient that stabilizes emulsions and suspensions in pharmaceutical products and lubricant in ophthalmic …

Cyclosporine

Cyclosporine is a calcineurin inhibitor known for its immunomodulatory properties that prevent organ transplant rejection and treat various inflammatory and autoimmune conditions. It is isolated from the fungus Beauveria nivea. Initially manufactured by Sandoz and approved for use by the FDA in 1983, cyclosporine is now available in various products...
Approved
Investigational
Vet approved
Matched Products: … RESTASIS 0.05% w/w OPHTHALMIC EMULSION …

Trimethoprim

Trimethoprim is an antifolate antibacterial agent that inhibits bacterial dihydrofolate reductase (DHFR), a critical enzyme that catalyzes the formation of tetrahydrofolic acid (THF) - in doing so, it prevents the synthesis of bacterial DNA and ultimately continued bacterial survival. Trimethoprim is often used in combination with sulfamethoxazole due to their...
Approved
Vet approved
Matched Mixtures name: … Polytrim Ophthalmic Solution …

Doxycycline

Doxycycline is a broad-spectrum antibiotic synthetically derived from oxytetracycline. It is a second-generation tetracycline that was first discovered in 1967. Second-generation tetracyclines exhibit lesser toxicity than first-generation tetracyclines. Doxycycline is used to treat a wide variety of gram-positive and gram-negative bacterial infections. It is also used to treat acne and...
Approved
Investigational
Vet approved

Calcium chloride

Calcium chloride is an ionic compound of calcium and chlorine. It is highly soluble in water and it is deliquescent. It is a salt that is solid at room temperature, and it behaves as a typical ionic halide. It has several common applications such as brine for refrigeration plants, ice...
Approved
Matched Mixtures name: … OSS (OPHTHALMIC BALANCED SALT SOLUTION) …

Tafluprost

A prostaglandin analogue ester prodrug used topically (as eye drops) to control the progression of glaucoma and in the management of ocular hypertension. Chemically, tafluprost is a fluorinated analog of prostaglandin F2-alpha. Tafluprost was approved for use in the U.S. on February 10, 2012.
Approved
Matched Mixtures name: … TAPCOM ophthalmic solution ... TAPCOM-S OPHTHALMIC SOLUTION ... TAPCOM-S ophthalmic solution 15 micrograms/ml + 5 mg/ml, solution in single-dose container …
Matched Products: … Tafluprost Ophthalmic ... TAFLOTAN ophthalmic solution 0.0015% ... Taflotan Ophthalmic Solution 0.0015% …

Pilocarpine

A naturally occurring alkaloid derived from the Pilocarpus plants, pilocarpine is a muscarinic acetylcholine agonist.[A262016, A262036] Pilocarpine is associated with parasympathomimetic effects by selectively working on muscarinic receptors. Pilocarpine is used to treat dry mouth and various ophthalmic conditions, including elevated intraocular pressure and glaucoma. The usage of glaucoma by...
Approved
Investigational
Matched Description: … [A262036] Pilocarpine is used to treat dry mouth and various ophthalmic conditions, including elevated …
Matched Mixtures name: … E-pilo 4 Ophthalmic Solution ... E-pilo 1 Ophthalmic Solution ... E-pilo 2 Ophthalmic Solution …
Matched Products: … Miocarpine Ophthalmic Solution 2% ... Miocarpine Ophthalmic Solution 4% ... Miocarpine Ophthalmic Solution 1% …

Levobunolol

A nonselective beta-adrenoceptor antagonist used in the treatment of glaucoma.
Approved
Matched Products: … Betagan 0.5% Ophthalmic Sol ... Levobunolol Hydrochloride Ophthalmic Solution ... Apo-levobunolol Ophthalmic Solution USP 0.5% …

Brimonidine

Brimonidine is an alpha-adrenergic agonist and 2-imidazoline derivative that was first introduced in 1996. It is considered to be a third generation alpha-2 aadrenergic receptor agonist, since it displays preferential binding at alpha-2 adrenoceptors over alpha-1 receptors. Brimonidine displays a higher selectivity toward the alpha-2 adrenergic receptors than clonidine or...
Approved
Matched Description: … [A36674] Brimonidine is also found in ophthalmic solutions in combination with [brinzolamide] under the ... [A178969] The ophthalmic solution of brimonidine was first approved by the FDA in 1996 as Alphagan [label …
Matched Mixtures name: … Brimonidine Tartrate/Timolol Maleate Ophthalmic Solution ... Brimonidine Tartrate/Timolol Maleate Ophthalmic Solution …
Matched Products: … Brimonidine Ophthalmic ... RIMONID Ophthalmic Solution 0.2% ... ALPHAGAN P Ophthalmic Solution 0.1% …

Gatifloxacin

Gatifloxacin is an antibiotic agent and a member of the fourth-generation fluoroquinolone family. It works by inhibiting the bacterial enzymes DNA gyrase and topoisomerase IV. It was first introduced by Bristol-Myers Squibb in 1999 under the brand name Tequin® for the treatment of respiratory tract infections. Gatifloxacin is available as...
Approved
Investigational
Withdrawn
Matched Description: … The FDA withdrew its approval for the use of non-ophthalmic drug products containing gatifloxacin due …
Matched Categories: … Ophthalmic Solutions …
Matched Products: … ZYMAR OPHTHALMIC SOLUTION 0.3% ... ZYMAR (OPHTHALMIC SOLUTION 0.3%) ... ZYMAXID (gatifloxacin ophthalmic solution) 0.5% …
Displaying drugs 76 - 100 of 154 in total