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Displaying drugs 1101 - 1125 of 15375 in total
A cholinesterase inhibitor that is rapidly absorbed through membranes. It can be applied topically to the conjunctiva. It also can cross the blood-brain barrier and is used when central nervous system effects are desired, as in the treatment of severe anticholinergic toxicity.
Approved
Investigational
Matched Description: … It also can cross the blood-brain barrier and is used when central nervous system effects are desired …
Matched Categories: … Antiglaucoma Preparations and Miotics …
Technetium Tc-99m exametazime is a radiopharmaceutical sold under the trade name Ceretec used in the detection of altered regional cerebral perfusion in stroke and other cerebrovascular diseases. It can also be used for the labelling of leukocytes to localise intra-abdominal infections and inflammatory bowel disease. Exametazime, also known as hexamethylpropyleneamine...
Approved
Matched Description: … under the trade name Ceretec used in the detection of altered regional cerebral perfusion in stroke and ... It can also be used for the labelling of leukocytes to localise intra-abdominal infections and inflammatory …
Matched Categories: … Indicators and Reagents …
Crisaborole is a novel oxaborole approved by FDA on December 14, 2016 as Eucrisa, a topical treatment of for mild to moderate atopic dermatitis. This non-steroidal agent is efficacious in improving disease severity, reducing the risk of infection and reducing the signs and symptoms in patients 2 years old and...
Approved
Investigational
Matched Description: … reducing the signs and symptoms in patients 2 years old and older. ... It reduces the local inflammation in the skin and prevents further exacerbation of the disease with a ... This non-steroidal agent is efficacious in improving disease severity, reducing the risk of infection and
Human papillomavirus type 11 L1 capsid protein antigen is contained in Gardasil, or a recombinant Human Papillomavirus Quadrivalent (Types 6, 11, 16, and 18) vaccine for intramuscular injection. It is an immunization for young men and women 9-26 years of age for the prevention of diseases caused by Human Papillomavirus...
Approved
Matched Description: … by Human Papillomavirus (HPV) types 6, 11, 16 and 18. ... antigen is contained in Gardasil, or a recombinant Human Papillomavirus Quadrivalent (Types 6, 11, 16, and ... It is an immunization for young men and women 9-26 years of age for the prevention of diseases caused …
Enprofylline is a derivative of theophylline which shares bronchodilator properties. Enprofylline is used in asthma, chronic obstructive pulmonary disease, and in the management of cerebrovascular insufficiency, sickle cell disease, and diabetic neuropathy. Long-term enprofylline administration may be associated with elevation in liver enzyme levels and unpredictable blood levels.
Approved
Experimental
Matched Description: … insufficiency, sickle cell disease, and diabetic neuropathy. ... Enprofylline is used in asthma, chronic obstructive pulmonary disease, and in the management of cerebrovascular ... Long-term enprofylline administration may be associated with elevation in liver enzyme levels and unpredictable …
Hydroxypropyl cellulose is an ether of cellulose where some of the hydroxyl groups of the cellulose have been hydroxypropylated forming -OCH2CH(OH)CH3 groups. Lacrisertis a formulation of hydroxypropyl cellulose that is used for artificial tears. It is used to treat syndromes characterized by insufficient tear production (keratoconjunctivitis sicca), recurrent corneal erosions,...
Approved
Matched Description: … neuroparalytic keratitis, and as a lubricant for artificial eyes. ... As a food additive, hydroxypropyl cellulose is used as a thickener and as an emulsion stabilizer. ... production (keratoconjunctivitis sicca), recurrent corneal erosions, decreased corneal sensitivity, exposure and
Samarium Sm 153 lexidronam is a radioactive medication used to treat pain caused by cancer that has spread to the bone. It is a radiopharmaceutical. Radiopharmaceuticals are radioactive agents that may be used to diagnose some diseases by studying the function of the body's organs or to treat certain diseases.Samarium...
Approved
Investigational
Matched Iupac: … hydrogen {[(hydrogen phosphonomethyl)({2-[(hydrogen phosphonomethyl)(phosphonomethyl)amino]ethyl})amino]methyl
Matched Description: … The radioactive samarium is taken up in the bone cancer area and gives off radiation that helps provide …
Rose bengal is a pink stain derived as an analogue of fluorescein. Its disodium salt in ophthalmic solutions has been used as a diagnostic agent in suspected damage to conjunctival and corneal cells. It is also used in laboratory settings, including the preparation of Foraminifera for microscopic analysis and suppression...
Approved
Investigational
Matched Description: … skin conditions such as eczema and psoriasis are being investigated in clinical trials. ... salt in ophthalmic solutions has been used as a diagnostic agent in suspected damage to conjunctival and ... also used in laboratory settings, including the preparation of Foraminifera for microscopic analysis and
Matched Categories: … Indicators and Reagents …
Levocabastine is a selective second-generation H1-receptor antagonist used for allergic conjunctivitis. Levocabastine was discovered at Janssen Pharmaceutica in 1979.
Approved
Investigational
Matched Iupac: … (3S,4R)-3-methyl-4-phenyl-1-[(1s,4s)-4-cyano-4-(4-fluorophenyl)cyclohexyl]piperidine-4-carboxylic acid …
Matched Categories: … Decongestants and Antiallergics …
Chikungunya virus (CHIKV) is a member of the Alphavirus genus that was first identified in Tanzania in 1952. It is spread primarily by the bite of infected mosquitos of the Aedes genus. Infection with CHIKV causes chikungunya fever, an illness characterized by acute fever and severe, persistent arthralgia. Prior to...
Approved
Matched Description: … , Asia, Europe, and the Indian and Pacific Oceans. ... In late 2013, the first cases were identified in the Caribbean, and it has since spread to most of the ... [A262051] Prior to 2013, chikungunya virus cases and outbreaks had been identified in countries in Africa …
A specific blocker of dopamine receptors. It speeds gastrointestinal peristalsis, causes prolactin release, and is used as antiemetic and tool in the study of dopaminergic mechanisms.
Approved
Investigational
Vet approved
Matched Description: … It speeds gastrointestinal peristalsis, causes prolactin release, and is used as antiemetic and tool …
Matched Categories: … Alimentary Tract and Metabolism …
Ethotoin is a hydantoin derivative and anticonvulsant. Ethotoin exerts an antiepileptic effect without causing general central nervous system depression. The mechanism of action is probably very similar to that of phenytoin. The latter drug appears to stabilize rather than to raise the normal seizure threshold, and to prevent the spread...
Approved
Matched Description: … Ethotoin is a hydantoin derivative and anticonvulsant. ... The latter drug appears to stabilize rather than to raise the normal seizure threshold, and to prevent …
Haloprogin is used as a topical ointment or cream in the treatment of Tinea infections. Tinea infections are superficial fungal infections caused by three species of fungi collectively known as dermatophytes (Trichophyton, Microsporum and Epidermophyton). Commonly these infections are named for the body part affected, including tinea corporis (general skin),...
Approved
Withdrawn
Matched Description: … of yeast membrane structure and function. ... Haloprogin is no longer available in the United States and has been discontinued. ... are named for the body part affected, including tinea corporis (general skin), tinea cruris (groin), and
Lumefantrine Co-Artemether (Riamet) has been investigated for the treatment of Malaria, Malaria, Falciparum, Malaria in Pregnancy, Uncomplicated Malaria, and Uncomplicated Knowlesi Malaria. Lumefantrine Co-Artemether is a tablet formulation of artemether and lumefantrine, a well-tolerated, fast-acting and effective blood schizontocidal drug that serves primarily in the treatment of uncomplicated falciparum malaria...
Approved
Investigational
Matched Description: … the production of free radicals to reduce blood antioxidants and glutathione. ... Lumefantrine Co-Artemether is a tablet formulation of artemether and lumefantrine, a well-tolerated, ... investigated for the treatment of Malaria, Malaria, Falciparum, Malaria in Pregnancy, Uncomplicated Malaria, and
A sulfone active against a wide range of bacteria but mainly employed for its actions against mycobacterium leprae. Its mechanism of action is probably similar to that of the sulfonamides which involves inhibition of folic acid synthesis in susceptible organisms. It is also used with pyrimethamine in the treatment of...
Approved
Investigational
Matched Categories: … dapsone and rifampicin ... dapsone, rifampicin and clofazimine …
An adrenergic agonist that acts predominantly at alpha adrenergic receptors and also stimulates the release of norepinephrine. It has been used primarily as a vasoconstrictor in the treatment of hypotension.
Approved
Investigational
Matched Description: … An adrenergic agonist that acts predominantly at alpha adrenergic receptors and also stimulates the release …
Matched Categories: … Adrenergic and Dopaminergic Agents …
Protokylol is a β-adrenergic receptor agonist used as a bronchodilator in Europe and the United States.
Approved
Vet approved
Matched Description: … Protokylol is a β-adrenergic receptor agonist used as a bronchodilator in Europe and the United States …
Matched Categories: … Epinephrine and similars …
Persistent forms of tuberculosis (TB) have proven to be a major cause of global morbidity and mortality and a cause for significant concern. Research in recent years has been geared toward the development of novel therapies that target persistent forms of this disease, which have shown resistance to standard therapy...
Approved
Matched Description: … and a cause for significant concern. ... Persistent forms of tuberculosis (TB) have proven to be a major cause of global morbidity and mortality ... It was the first TB drug developed by a nonprofit organization, known as TB Alliance, and was granted …
Gadolinium is under investigation in Hypertension, ACUTE KIDNEY INJURY, and Chronic Kidney Disease. Gadolinium has been investigated for the basic science of CAD, Multiple Sclerosis, and Coronary Artery Disease.
Approved
Investigational
Matched Description: … Gadolinium is under investigation in Hypertension, ACUTE KIDNEY INJURY, and Chronic Kidney Disease. ... Gadolinium has been investigated for the basic science of CAD, Multiple Sclerosis, and Coronary Artery …
Dibenzepin is approved for use in Europe.
Approved
Matched Iupac: … 9-[2-(dimethylamino)ethyl]-2-methyl-2,9-diazatricyclo[9.4.0.0^{3,8}]pentadeca-1(15),3,5,7,11,13-hexaen …
In recent years, various extended half-life factor VIII and factor IX preparations have been studied and gained approval. In order to extend half-lives, techniques such as fusion to protein conjugates (Fc part of IgG1 or albumin), chemical modification (PEGylation), and protein sequence modification have been utilized. Also known as, BAY94-9027,...
Approved
Investigational
Matched Description: … and gained approval. ... has been filed with the FDA in August 2017 and FDA approved in August 2018. ... In recent years, various extended half-life factor VIII and factor IX preparations have been studied …
Nitrofurantoin is a nitrofuran antibiotic used to treat uncomplicated urinary tract infections.[L6856,L6859,L6862] Nitrofurantoin is converted by bacterial nitroreductases to electrophilic intermediates which inhibit the citric acid cycle as well as synthesis of DNA, RNA, and protein. This drug is more resistant to the development of bacterial resistance because it acts...
Approved
Vet approved
Matched Description: … to electrophilic intermediates which inhibit the citric acid cycle as well as synthesis of DNA, RNA, and
Evolocumab is a monoclonal antibody designed for the treatment of hyperlipidemia by Amgen. It is a subcutaneous injection approved by the FDA for individuals on maximum statin therapy who still require additional LDL-cholesterol lowering. It is approved for both homozygous and heterozygous familial cholesterolemia as an adjunct to other first-line...
Approved
Matched Description: … Evolocumab is designed to bind to PCSK9 and inhibit PCSK9 from binding to LDL receptors on the liver ... It is approved for both homozygous and heterozygous familial cholesterolemia as an adjunct to other first-line …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Nylidrin, also known as buphenine belongs to the category of drugs called vasodilators, which relax blood vessels and increase blood flow. Nylidrin is a peripheral vasodilator. Some studies show the evidence of improving cognitive impairment in selected individuals, such as geriatric patients with mild to moderate symptoms of cognitive, emotional...
Approved
Matched Description: … known as _buphenine_ belongs to the category of drugs called _vasodilators_, which relax blood vessels and ... This effect may help to improve memory/judgment, improve walking ability, and support the healing of ... selected individuals, such as geriatric patients with mild to moderate symptoms of cognitive, emotional and
Matched Categories: … Genito Urinary System and Sex Hormones …
Chromium picolinate has a chemical formula CrPic3 and reddish-pink color. It is a coordination complex consisting of chromium(III) and picolinic acid. Chromium picolinate is used as a nutritional supplement for optimal insulin function in patients with Type 2 diabetes or promotion of weight loss. Chromium ions are shown to regulate...
Approved
Matched Description: … Chromium picolinate has a chemical formula CrPic3 and reddish-pink color. ... It is a coordination complex consisting of chromium(III) and picolinic acid. ... Chromium ions are shown to regulate insulin by promoting glucose utilization and increasing the sensitivity …
Displaying drugs 1101 - 1125 of 15375 in total