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Displaying drugs 101 - 125 of 154 in total

Cyclopentolate

A parasympatholytic anticholinergic used solely to obtain mydriasis or cycloplegia.
Approved
Matched Mixtures name: … CYCLOMYDRIL OPHTHALMIC SOLUTION ... CYCLOMYDRIL STERILE OPHTHALMIC SOLUTION …
Matched Products: … CYCLOGYL STERILE OPHTHALMIC SOLUTION 1% ... CYCLOGYL 1%-STERILE OPHTHALMIC SOLUTION 15ML ... Dom-cyclopentolate HCl Ophthalmic Solution-1% …

Travoprost

Travoprost is a synthetic isopropyl ester prodrug of a prostaglandin F2alpha (F2α) analogue and selective FP prostanoid receptor agonist. It is used to decrease intraocular pressure in open-angle glaucoma and ocular hypertension. Unlike other prostaglandin analogues, travoprost demonstrates full agonism and high selectivity at the prostanoid receptor, reporting a higher...
Approved
Matched Products: … Travoprost Ophthalmic ... Travoprost Ophthalmic Solution ... Travoprost Ophthalmic Solution 0.004% …

Nepafenac

Nepafenac is a non-steroidal anti-inflammatory prodrug (NSAID) usually sold as a prescription eye drop. It is used to treat pain and inflammation associated with cataract surgery.
Approved
Investigational
Matched Products: … NEVANAC OPHTHALMIC SUSPENSION 0.1% ... Ilevro (Nepafenac Ophthalmic Suspension 0.3%) ... NEVANAC (NEPAFENAC OPHTHALMIC SUSPENSION) 0.1% …

Dorzolamide

Dorzolamide is a non-bacteriostatic sulfonamide derivative and topical carbonic anhydrase (CA) inhibitor that treats elevated intraocular pressure (IOP) associated with open-angle glaucoma and ocular hypertension. It works by blocking an enzyme in the ciliary process that regulates ion balance and fluid pressure in the eyes. Unlike oral CA inhibitors, dorzolamide...
Approved
Matched Description: … [A1304] First marketed in 1995,[A190624] dorzolamide is available in ophthalmic solutions as monotherapy …
Matched Mixtures name: … COSOPT OPHTHALMIC SOLUTION ... COSOPT OPHTHALMIC SOLUTION ... COSOPT-S OPHTHALMIC SOLUTION …
Matched Products: … Dorzolamide Hydrochloride Ophthalmic Solution 2%, 10mL Ophthalmic Solution 2%, 10mL ... TRUSOPT OPHTHALMIC SOLUTION ... TRUSOPT OPHTHALMIC SOLUTION 2% …

Timolol

Timolol is a nonselective beta-adrenergic antagonist given in an eye drop solution to reduce intraocular pressure, or pressure in the eyes. It is also used in tablet form as a drug to treat hypertension. Timolol was first approved by the FDA in 1978. This drug is marketed by several manufacturers...
Approved
Matched Mixtures name: … COSOPT OPHTHALMIC SOLUTION ... TAPCOM ophthalmic solution ... COSOPT OPHTHALMIC SOLUTION …
Matched Products: … TIMOPTOL XE 0.5% OPHTHALMIC SOLN ... TIMOPTOL OPHTHALMIC SOLUTION 0.5% ... TIMOPTOL-XE OPHTHALMIC SOLUTION 0.5% …

Tropicamide

Tropicamide is an alkaloid atropine‐derived anticholinergic drug and a non‐selective antagonist of muscarinic acetylcholine (mACh) receptors. Usually available in ophthalmic formulations, tropicamide is used to cause mydriasis and cycloplegia for eye exams or ocular procedures. It is also used in combination with hydroxyamphetamine for the same indication. Oral tropicamide has...
Approved
Investigational
Matched Description: … [A230103] Usually available in ophthalmic formulations, tropicamide is used to cause mydriasis and cycloplegia …
Matched Products: … MYDRIACYL 1% OPHTHALMIC PREPARATION ... MYDRIACYL STERILE OPHTHALMIC SOLUTION 1% ... MYDRIACYL STERILE OPHTHALMIC SOLUTION 0.5% …

Emedastine

Emedastine is an antihistamine used in eye drops to treat allergic conjunctivitis.
Approved
Matched Products: … Emadine Sterile Ophthalmic Solution 0.05% ... EMADINE 0.05% STERILE OPHTHALMIC SOLUTION …

Epinastine

Epinastine is used for the prevention of itching associated with allergic conjunctivitis. It has a multi-action effect that inhibits the allergic response in 3 ways: 1. stabilizes mast cells by preventing mast cell degranulation to control the allergic response, 2. prevents histamine binding to both the H1- and H2-receptors to...
Approved
Investigational
Matched Products: … RELESTAT OPHTHALMIC SOLUTION 0.5 mg/ml ... RELESTAT (EPINASTINE HYDROCHLORIDE OPHTHALMIC SOLUTION 0.5 MG/ML) …

Brinzolamide

Brinzolamide is a highly specific, non-competitive, reversible carbonic anhydrase II (CA-II) inhibitor indicated to reduce ocular pressure in patients with ocular hypertension or open-angle glaucoma. Although the exact pathophysiology of glaucoma is still unknown, one of the main hallmarks of this disease is vascular dysregulation and abnormalities.[A2049,A2051] The resulting vascular...
Approved
Matched Products: … AZOPT OPHTHALMIC SUSPENSION 1% ... AZOPT 10MG/ML OPHTHALMIC SUSPENSION …

Chlortetracycline

Chlortetracycline is a tetracycline antibiotic, and historically the first member of this class to be identified. It was discovered in 1945 by the scientist, Benjamin Minge Duggar, working at Lederle Laboratories under the supervision of Yellapragada Subbarow. He discovered that this antibiotic was the product of an actinomycete strain he...
Approved
Investigational
Vet approved
Matched Products: … CHLORTRALIM OPHTHALMIC OINTMENT 1% …

Moxifloxacin

Moxifloxacin is a synthetic fluoroquinolone antibiotic agent. Bayer AG developed the drug (initially called BAY 12-8039) and it is marketed worldwide (as the hydrochloride) under the brand name Avelox (in some countries also Avalox) for oral treatment.
Approved
Investigational
Matched Products: … Moxifloxacin Ophthalmic ... Moxifloxacin ophthalmic solution ... Moxifloxacin Ophthalmic Solution …

Carbamoylcholine

Carbamoylcholine, also known as carbachol, is a muscarinic agonist discovered in 1932. Carbamoylcholine was initially used as a treatment for migraines, induction of diuresis, and other parasympathetic effects. Carbamoylcholine was granted FDA approval on 28 September 1972.
Approved
Matched Products: … Miostat Ophthalmic Liq 0.01% …

Chloramphenicol

An antibiotic first isolated from cultures of Streptomyces venezuelae in 1947 but now produced synthetically. It has a relatively simple structure and was the first broad-spectrum antibiotic to be discovered. It acts by interfering with bacterial protein synthesis and is mainly bacteriostatic. (From Martindale, The Extra Pharmacopoeia, 29th ed, p106)...
Approved
Vet approved
Withdrawn
Matched Products: … OPTIVIS OPHTHALMIC OINTMENT ... PMS-chloramphenicol Ophthalmic Ointment ... PMS-chloramphenicol Ophthalmic Soln 0.5% …

Gentamicin

Gentamicin is a bactericidal aminoglycoside that was discovered and isolated from Micromonospora purpurea in 1963. It is one of the most frequently prescribed aminoglycosides due to its spectrum of activity, low cost, and availability.[A234339,A234354] Gentamicin is effective against both gram-positive and gram-negative organisms but is particularly useful for the treatment...
Approved
Vet approved
Matched Mixtures name: … Garasone Ophthalmic Ointment ... Betamycin Ophthalmic/otic Solution ... Garasone Ophthalmic and Otic Solution …
Matched Products: … Garatec Ophthalmic Dps 5mg/ml ... Garamycin Ophthalmic Drops 0.3% ... Garamycin Ophthalmic Ointment 0.3% …

Isosorbide

Isosorbide was previously available in an oral formulation for the reduction of intraocular pressure. It was approved by the FDA in 1980, but has since been discontinued. Currently, isosorbide is an organic nitrate currently available in the isosorbide mononitrate and isosorbide dinitrate forms, and is used for the prevention of...
Approved
Investigational

Ketotifen

Ketotifen is a benzocycloheptathiophene derivative with potent antihistaminic and mast cell stabilizing properties. It has a similar structure to some other first-generation antihistamines such as cyproheptadine and azatadine. Ketotifen was first developed in Switzerland in 1970 by Sandoz Pharmaceuticals and was initially marketed for the treatment of anaphylaxis. In the...
Approved
Matched Description: … [A231204] In the US, it is now used in an over-the-counter ophthalmic formulation for the treatment of …
Matched Products: … Jamp Ketotifen Ophthalmic ... Ketotifen Ophthalmic Solution ... ALAWAY OPHTHALMIC SOLUTION 0.25mg/mL …

Perfluorohexyloctane

Perfluorohexyloctane is a semifluorinated alkane that contains six perfluorinated carbon atoms and eight hydrogenated carbon atoms. It is an inert, slightly amphiphilic compound. Because it is a completely non-aqueous liquid, microbial growth is not possible; therefore, its drug products do not need to be combined with any preservative.[A259746, A259751] Perfluorohexyloctane...
Approved
Matched Categories: … Ophthalmic Solutions …

Dexamethasone

Dexamethasone, or MK-125, is a corticosteroid fluorinated at position 9 used to treat endocrine, rheumatic, collagen, dermatologic, allergic, ophthalmic, gastrointestinal, respiratory, hematologic, neoplastic, edematous, and other conditions. Developed in 1957, it is structurally similar to other corticosteroids like hydrocortisone and prednisolone. Dexamethasone was granted FDA approval on 30 October 1958....
Approved
Investigational
Vet approved
Matched Description: … corticosteroid fluorinated at position 9 used to treat endocrine, rheumatic, collagen, dermatologic, allergic, ophthalmic …
Matched Mixtures name: … TOBRADEX OPHTHALMIC OINTMENT ... TOBRADEX OPHTHALMIC SUSPENSION ... MAXITROL STERILE OPHTHALMIC OINTMENT …
Matched Products: … MAXIDEX OPHTHALMIC SUSPENSION ... MAXIDEX STERILE OPHTHALMIC OINTMENT 0.1% ... MAXIDEX STERILE OPHTHALMIC SUSPENSION 0.1% …

Erythromycin

Erythromycin is a bacteriostatic antibiotic drug produced by a strain of Saccharopolyspora erythraea (formerly Streptomyces erythraeus) and belongs to the macrolide group of antibiotics which consists of Azithromycin, Clarithromycin, Spiramycin and others. It was originally discovered in 1952. Erythromycin is widely used for treating a variety of infections, including those...
Approved
Investigational
Vet approved
Matched Products: … Erymycin Ophthalmic Ointment 5mg/g ... Erythromycin Ophthalmic Ointment USP ... Erythromycin Ophthalmic Ointment U.S.P. …

Loteprednol

Approved
Experimental
Matched Mixtures name: … ALREX STERILE OPHTHALMIC SUSPENSION 0.2% ... ZYLET (STERILE OPHTHALMIC SUSPENSION) ... LOTEMAX (STERILE OPHTHALMIC SUSPENSION 0.5%) …

Brilliant blue G

Brilliant Blue G is used in an ophthalmic solution for staining the internal limiting membrane (ILM) of the eye during ophthalmic procedures.[A188841,A188844] This membrane is thin and translucent, making it difficult to identify during eye surgeries that require high levels of visual accuracy. Brilliant blue G, like its name, imparts...
Approved
Matched Description: … of the eye during ophthalmic procedures. ... It was approved by the FDA for ophthalmic use on December 20, 2019.[L10830] ... Brilliant Blue G is used in an ophthalmic solution for staining the internal limiting membrane (ILM) …

Maribavir

Maribavir is an inhibitor of the cytomegalovirus (CMV; HHV5) pUL97 kinase which is used to treat CMV infections in patients post-transplantation. Most standard CMV therapies, such as ganciclovir or foscarnet, target CMV DNA polymerase - while generally effective, these medications tend to promote the development of CMV resistance to DNA...
Approved
Investigational
Matched Description: … [L39322] Most standard CMV therapies, such as [ganciclovir] or [foscarnet], target CMV DNA polymerase …

Prednisolone

Prednisolone is a glucocorticoid similar to cortisol used for its anti-inflammatory, immunosuppressive, anti-neoplastic, and vasoconstrictive effects. Prednisolone was granted FDA approval on 21 June 1955.
Approved
Vet approved
Matched Mixtures name: … EXOPRED (OPHTHALMIC SUSPENSION) …

Oxymetazoline

Oxymetazoline is an imidazole derivative and a potent, direct-acting alpha (α)-adrenergic agonist with affinity to both α1- and α2-adrenoceptors. Oxymetazoline is available in various formulations with a wide variety of clinical implications. The topical formulation of the drug is used to treat persistent facial redness in adults. As an effective...
Approved
Investigational
Matched Description: … [L15057] In July 2020, the FDA approved the use of an ophthalmic formulation of oxymetazoline (Upneeq …
Matched Products: … Ophthalmic Sol 0.025% …

Xylometazoline

Xylometazoline is an imidazoline derivative with sympathomimetic and nasal decongestant activity. Xylometazoline works by binding to alpha (α)-adrenergic receptors to cause vasoconstriction of nasal blood vessels. Xylometazoline is available in over-the-counter (OTC) nasal sprays or drops to temporarily relieve nasal congestion due to cold, hay fever or other respiratory allergies....
Approved
Investigational
Matched Mixtures name: … Ophtrivin A Ophthalmic Dps …
Displaying drugs 101 - 125 of 154 in total