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Displaying drugs 1701 - 1725 of 15232 in total

Mitomycin

Mitomycin is an antineoplastic antibiotic first isolated by Japanese microbiologists in the 1950s from cultures of Streptomyces caespitosus.[L12867,A193419] It is an alkylating agent that inhibits DNA synthesis (and, at higher concentrations, RNA and protein synthesis) by cross-linking the complementary strands of the DNA double helix. Few other antibiotics have been...
Approved
Matched Iupac: … -1(9),11-dien-8-yl]methyl carbamate ... [(4S,6S,7R,8S)-11-amino-7-methoxy-12-methyl-10,13-dioxo-2,5-diazatetracyclo[7.4.0.0^{2,7}.0^{4,6}]trideca …
Matched Description: … , RNA and protein synthesis) by cross-linking the complementary strands of the DNA double helix. ... [L12867,A193419] It is an alkylating agent that inhibits DNA synthesis (and, at higher concentrations …
Matched Categories: … Indicators and Reagents ... Antineoplastic and Immunomodulating Agents ... Cytotoxic Antibiotics and Related Substances …
Matched Products: … MITOMICINA 20 ... MUTAMYCIN 20 MG ... RIPTAM 20 MG POLVO LIOFILIZADO …

Naphazoline

Naphazoline is a rapid acting imidazoline sympathomimetic vasoconstrictor of ocular or nasal artierioles[L5804,L5807]. It acts to decrease congestion and is found in many over the counter (OTC) eye drops and nasal preparations[L5804,L5807]. Naphazoline was first developed in 1942 as a nasal formulation for congestion .
Approved
Investigational
Matched Iupac: … 2-[(naphthalen-1-yl)methyl]-4,5-dihydro-1H-imidazole …
Matched Description: … It acts to decrease congestion and is found in many over the counter (OTC) eye drops and nasal preparations …
Matched Mixtures name: … SULFARHIN BURUN MERHEMI, 20 G ... Lubricant and Redness Reliever ... Eye Drops Redness and Dry Eye Relief …
Matched Categories: … Decongestants and Antiallergics …

Monobenzone

Monobenzone is the monobenzyl ether of hydroquinone used medically for depigmentation. Monobenzone occurs as a white, almost tasteless crystalline powder, soluble in alcohol and practically insoluble in water. It exerts a depigmenting effect on skin of mammals by increasing the excretion of melanin from the melanocytes. It may also cause...
Approved
Matched Description: … It may also cause destruction of melanocytes and permanent depigmentation. ... Monobenzone occurs as a white, almost tasteless crystalline powder, soluble in alcohol and practically …
Matched Products: … Benoquin Crm 20% ... MONOTONE %20 KREM, 113,5 GR …

Lornoxicam

Lornoxicam (chlortenoxicam) is a new nonsteroidal anti-inflammatory drug (NSAID) of the oxicam class with analgesic, anti-inflammatory and antipyretic properties. Lornoxicam differs from other oxicam compounds in its potent inhibition of prostaglandin biosynthesis, a property that explains the particularly pronounced efficacy of the drug. Lornoxicam is approved for use in Japan.
Approved
Investigational
Matched Iupac: … 6-chloro-4-hydroxy-2-methyl-1,1-dioxo-N-(pyridin-2-yl)-2H-1λ⁶-thieno[2,3-e][1,2]thiazine-3-carboxamide …
Matched Description: … new nonsteroidal anti-inflammatory drug (NSAID) of the oxicam class with analgesic, anti-inflammatory and …
Matched Mixtures name: … LORNOPAR 8/300 MG EFERVESAN TABLET ,20 ADET …
Matched Categories: … Antiinflammatory and Antirheumatic Products ... Antiinflammatory and Antirheumatic Products, Non-Steroids …
Matched Products: … XEFO 4 MG FILM KAPLI TABLET, 20 ADET ... XEFO 8 MG FILM KAPLI TABLET, 20 ADET ... QUANDO 8 MG FILM KAPLI TABLET, 20 ADET …

Trospium

Trospium is an antispasmodic agent used to treat the symptoms of overactive bladder, a condition that causes the bladder muscles to contract uncontrollably. An overactive bladder leads to an increased urge to urinate, frequent urination, and sometimes, loss of control over urination. Trospium is manufactured by Indevus Pharmaceutical Inc. and...
Approved
Matched Description: … [L6208] An overactive bladder leads to an increased urge to urinate, frequent urination, and sometimes ... [L6208] Trospium is manufactured by _Indevus Pharmaceutical Inc._ and was granted FDA approval in 2007 …
Matched Categories: … trospium and analgesics ... Alimentary Tract and Metabolism ... Genito Urinary System and Sex Hormones ... Drugs for Urinary Frequency and Incontinence …
Matched Products: … SPASMOLYT TABLET 20 MG ... สปัสโม-ลิท 20 มิลลิกรัม ... Trospium Sandoz 20 mg - Filmtabletten …

Acemetacin

Acemetacin is a carboxymethyl ester of indometacin. It is a potent non-steroidal anti-inflammatory drug, derived from the indol-3-acetic acid, whose activity is thought to be mainly through its active metabolite indomethacin. In clinical trials, acemetacin exhibits a better gastric tolerability compared to its active metabolite indometacin. It was developed by...
Approved
Investigational
Matched Iupac: … 2-({2-[1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl]acetyl}oxy)acetic acid …
Matched Description: … Merck and Company in Germany as an attempt to provide a safer drug but other than the amelioration on ... the gastrointestinal effects, the metabolism of acetamicin led to the formation of indomethacin and …
Matched Categories: … Acetic Acid Derivatives and Related Substances ... Antiinflammatory and Antirheumatic Products ... Antiinflammatory and Antirheumatic Products, Non-Steroids …
Matched Products: … ACETUDIL FORTE 60 MG KAPSÜL, 20 ADET ... RANTUDIL FORTE 60 MG KAPSUL, 20 ADET ... ROMACTİL FORTE 60 MG KAPSÜL, 20 ADET …

Poloxamer 188

Poloxamer 188 (P188) is a nonionic block linear copolymer that exhibits rheologic, anti-thrombotic, anti-inflammatory, and cytoprotective activities in various tissue injury models . Composed of two hydrophilic side-chains attached to a hydrophobic center core , its average molecular weight is 8400 Daltons. P188 was originally approved by the FDA in...
Approved
Investigational
Matched Description: … mouthwash, and used in various cosmetic, industrial and pharmaceutical applications. ... of _in vivo_ and _in vitro_ models [A27218]. ... ) is a nonionic block linear copolymer that exhibits rheologic, anti-thrombotic, anti-inflammatory, and …
Matched Products: … Shur-clens Soln 20% …

Trimebutine

Trimebutine is a spasmolytic agent that regulates intestinal and colonic motility and relieves abdominal pain with antimuscarinic and weak mu opioid agonist effects. It is marketed for the treatment of irritable bowel syndrome (IBS) and lower gastrointestinal tract motility disorders, with IBS being one of the most common multifactorial GI...
Approved
Matched Description: … Trimebutine is a spasmolytic agent that regulates intestinal and colonic motility and relieves abdominal ... pain with antimuscarinic and weak mu opioid agonist effects. ... Trimebutine is not a FDA-approved drug, but it is available in Canada and several other international …
Matched Categories: … Alimentary Tract and Metabolism ... Synthetic Anticholinergics, Esters With Tertiary Amino Group …
Matched Products: … DEBRIDAT 100 MG TABLET, 20 ADET ... DEBRUTIN 100 MG TABLET, 20 ADET ... TRIBUDAT 100MG TABLET, 20 ADET …

Potassium guaiacolsulfonate

Guaiacolsulfonate is an aromatic sulfonic acid. Potassium guaiacolsulfonate salt is an expectorant that thins the mucus in the lungs and reduces chest congestion.
Approved
Experimental
Matched Description: … Potassium guaiacolsulfonate salt is an expectorant that thins the mucus in the lungs and reduces chest …
Matched Categories: … Methyl Ethers …

Obinutuzumab

Obinutuzumab is a humanized monoclonal antibody used as a combination treatment with chlorambucil to treat patients with untreated chronic lymphocytic leukemia. It was approved by the FDA in November 2013 and is marketed under the brand name Gazyva. There is a black box warning of fatal Hepatitis B Virus (HBV)...
Approved
Investigational
Matched Description: … It was approved by the FDA in November 2013 and is marketed under the brand name Gazyva. ... There is a black box warning of fatal Hepatitis B Virus (HBV) reactivation and fatal Progressive Multifocal …
Matched Categories: … CD20 (Clusters of Differentiation 20) inhibitors ... Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES …

Idarubicin

An orally administered anthracycline antineoplastic. The compound has shown activity against breast cancer, lymphomas and leukemias, together with the potential for reduced cardiac toxicity.
Approved
Matched Description: … The compound has shown activity against breast cancer, lymphomas and leukemias, together with the potential …
Matched Categories: … Anthracyclines and Related Substances ... Antineoplastic and Immunomodulating Agents ... Cytotoxic Antibiotics and Related Substances …
Matched Products: … Idarubicin Accord 20 mg/20 ml Injektionslösung ... İDAMEN IV 20 MG/20 ML ENJEKSİYONLUK ÇÖZELTİ İÇEREN FLAKON, 1 FLAKON ... ZADOSS 20 MG/20 ML I.V. ENJEKSIYONLUK ÇÖZELTI IÇEREN FLAKON, 1 ADET …

Edetate calcium disodium anhydrous

Edetate calcium disodium is a metal ion chelator used to reduce blood concentrations and depot stores of lead from the body. It is on the World Health Organization Model List of Essential Medicines. Edetate calcium disodium was granted FDA approval on 16 July 1953.
Approved
Matched Description: … Edetate calcium disodium is a metal ion chelator used to reduce blood concentrations and depot stores …
Matched Categories: … Diet, Food, and Nutrition …
Matched Products: … EDETATO CALCICO DISODICO 20% ... โซเดียมแคลเซียมเอดีเตท ชนิดฉีด (20%) …

Aurothioglucose

Aurothioglucose, also known as gold thioglucose, was formerly used to treat rheumatoid arthritis. Contemporary research on the effect of gold salts treatment began in 1935, primarily to reduce inflammation and to slow disease progression in patients with rheumatoid arthritis . The use of gold compounds has decreased since the 1980s...
Approved
Withdrawn
Matched Description: … use of gold compounds has decreased since the 1980s owing to numerous side effects, limited efficacy, and ... Contemporary research on the effect of gold salts treatment began in 1935, primarily to reduce inflammation and ... replaced with the use of various current disease modifying anti-rheumatic drugs (DMARDs) like methotrexate and …
Matched Categories: … Antiinflammatory and Antirheumatic Products …

Rimexolone

Rimexolone is a 1% eye drop solution is a glucocorticoid steroid. It is used to treat inflammation in the eye. It is marketed as Vexol.
Approved
Matched Categories: … Sex Hormones and Insulins ... Hormones, Hormone Substitutes, and Hormone Antagonists …

Meradimate

Meradimate, before known as menthyl anthranilate, is used in a maximal concentration of 5% in different products as a UV filter. It is currently required to be named as meradimate in all FDA approved OTC products. Meradimate is approved by the FDA and Health Canada to be used as an...
Approved
Matched Iupac: … 5-methyl-2-(propan-2-yl)cyclohexyl 2-aminobenzoate …
Matched Description: … Meradimate is approved by the FDA and Health Canada to be used as an ingredient in sunblocking products …
Matched Mixtures name: … Principal Secret Reclaim Sunscreen For Face and Body SPF 30 ... Laura mercier Tinted Moisturizer SPF-20 Walnut SPF-20 Walnut ... Pro-Tect Sports Sunscreen SPF 20 …

Ademetionine

Physiologic methyl radical donor involved in enzymatic transmethylation reactions and present in all living organisms. It possesses anti-inflammatory activity and has been used in treatment of chronic liver disease. (From Merck, 11th ed)
Approved
Investigational
Nutraceutical
Matched Iupac: … (2S)-2-amino-4-({[(2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl}(methyl)sulfaniumyl …
Matched Description: … Physiologic methyl radical donor involved in enzymatic transmethylation reactions and present in all ... It possesses anti-inflammatory activity and has been used in treatment of chronic liver disease. …
Matched Categories: … Amino Acids and Derivatives ... Alimentary Tract and Metabolism ... Amino Acids, Peptides, and Proteins ... Nucleic Acids, Nucleotides, and Nucleosides …

Finerenone

Finerenone, or BAY 94-8862, is a mineralocorticoid receptor antagonist indicated to reduce the risk of sustained decline in glomerular filtration rate, end stage kidney disease, cardiovascular death, heart attacks, and hospitalization due to heart failure in adults with chronic kidney disease associated with type II diabetes mellitus.[A236519,L34739] Patients with kidney...
Approved
Investigational
Matched Description: … [A236544] Spironolactone has low selectivity and affinity for the receptor; it dissociates quickly and ... [A236544] Eplerenone is more selective and has longer lasting effects. ... can also have effects at the androgen, progesterone, and glucocorticoid receptors. …
Matched Products: … KERENDİA 20 MG FİLM KAPLI TABLET, 28 ADET ... KERENDİA 20 MG FİLM KAPLI TABLET, 98 ADET ... KERENDİA 10 MG FİLM KAPLI TABLET, 28 ADET …

Sodium phosphate, dibasic

Approved
Matched Mixtures name: … Aminosyn II 8.5% M In 20% Dextrose (dual Chamber) ... Aminosyn II and Dextrose ... Monobasic Sodium Phosphate and Dibasic Sodium Phosphate …

Cefaclor

Semisynthetic, broad-spectrum antibiotic derivative of cephalexin.
Approved
Matched Mixtures name: … SEFKLAV 250/62.5 MG EFERVESAN TABLET, 20 ADET ... SEFKLAV 500/125 MG EFERVESAN TABLET, 20 ADET ... SEFKLAV 1000/125 MG EFERVESAN TABLET, 20 ADET …
Matched Products: … CEFEC 250 MG EFERVESAN TABLET, 20 ADET ... CEC 250 MG EFERVESAN TABLET, 20 ADET ... CEC 500 MG EFERVESAN TABLET, 20 ADET …

Asenapine

Developed by Schering-Plough after its merger with Organon International, asenapine is a sublingually administered, atypical antipsychotic for treatment of schizophrenia and acute mania associated with bipolar disorder. Asenapine also belongs to the dibenzo-oxepino pyrrole class. It is also for severe post-traumatic stress disorder nightmares in soldiers as an off-label use....
Approved
Matched Iupac: … 9-chloro-4-methyl-13-oxa-4-azatetracyclo[12.4.0.0^{2,6}.0^{7,12}]octadeca-1(14),7,9,11,15,17-hexaene …
Matched Description: … International, asenapine is a sublingually administered, atypical antipsychotic for treatment of schizophrenia and …
Matched Categories: … Diazepines, Oxazepines, Thiazepines and Oxepines …
Matched Products: … SYCREST 10MG DILALTI TABLET, TABLET, 20 ADET ... SYCREST 5MG DILALTI TABLET, TABLET, 20 ADET …

Methylprednisolone aceponate

Approved
Vet approved
Matched Products: … ADVANTAN S % 0.1 COZELTI, 20 ML …

Pregnenolone

A 21-carbon steroid, derived from cholesterol and found in steroid hormone-producing tissues. Pregnenolone is the precursor to gonadal steroid hormones and the adrenal corticosteroids.
Approved
Experimental
Matched Description: … A 21-carbon steroid, derived from cholesterol and found in steroid hormone-producing tissues. ... Pregnenolone is the precursor to gonadal steroid hormones and the adrenal corticosteroids. …
Matched Categories: … Hormones, Hormone Substitutes, and Hormone Antagonists …

Baclofen

Baclofen is a gamma-aminobutyric acid (GABA) agonist used as a skeletal muscle relaxant. Although originally designed in 1962 to treat epilepsy, baclofen was not effective in treating this condition but instead was shown to reduce spasticity in selected patients. Baclofen was reintroduced in 1971 as a treatment for spasticity and...
Approved
Matched Description: … [A245338] Baclofen was reintroduced in 1971 as a treatment for spasticity and was later approved by the ... [L39429] Baclofen was investigated for use in alcohol dependence and withdrawal; however, evidence ... used to manage severe muscle spasms of cerebral or spinal cord origins, including multiple sclerosis and …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Products: … Baclofen-20 ... BACLOFEN 10 MG/ 20 ML ... BACLOFEN 40 MG / 20 ML …

Apremilast

Apremilast, also known as Otezla, is a phosphodiesterase 4 (PDE4) inhibitor used to treat various types of symptoms resulting from certain inflammatory autoimmune diseases. It belongs to the same drug class as Roflumilast and Crisaborole.[A181244,L7495] Initially approved in 2014, it is marketed by Celgene. In July 2019, apremilast was granted...
Approved
Investigational
Matched Description: … It belongs to the same drug class as [Roflumilast] and [Crisaborole]. ... associated with Behcet's disease, an autoimmune condition that causes recurrent skin, blood vessel, and …
Matched Mixtures name: … OTEZLA (10 MG 20 MG 30 MG) ... OTEZLA (10 MG 20 MG 30 MG) ... OTEZLA (10 MG 20 MG 30 MG) …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … OTEZLA FILM-COATED TABLETS 20 MG …

Methylprednisolone hemisuccinate

A water-soluble ester of methylprednisolone used for cardiac, allergic, and hypoxic emergencies.
Approved
Matched Description: … A water-soluble ester of methylprednisolone used for cardiac, allergic, and hypoxic emergencies. …
Matched Categories: … Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … CORTİPOL 20 MG I.M./I.V. ... METICURE 20 MG IM/IV ENJEKSIYON ICIN LIYOFIZE TOZ ICEREN FLAKON, 1 ADET ... PRECORT-LIYO 20 MG IM/IV ENJEKSIYON ICIN LIYOFILIZE TOZ ICEREN AMPUL, 1 AMPUL …
Displaying drugs 1701 - 1725 of 15232 in total