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Displaying drugs 176 - 200 of 1455 in total

Ivosidenib

Ivosidenib is a first-in-class isocitrate dehydrogenase-1 (IDH1) inhibitor. IDH1 is an enzyme that is often mutated and overexpressed in some cancers, leading to aberrant cell growth and proliferation. Ivosidenib inhibits mutated IDH1, blocking the enzymatic activity and further differentiation of cancer cells. Ivosidenib was granted accelerated approval by the FDA...
Approved
Investigational

Flucloxacillin

Antibiotic analog of cloxacillin.
Approved
Investigational

Infigratinib

Infigratinib is a pan-fibroblast growth factor receptor (FGFR) kinase inhibitor. By inhibiting the FGFR pathway, which is often aberrated in cancers such as cholangiocarcinoma, infigratinib suppresses tumour growth. Cholangiocarcinoma is the most common primary malignancy affecting the biliary tract and the second most common primary hepatic malignancy. Infitratinib is a...
Approved
Investigational

Loracarbef

Loracarbef is a carbacephem antibiotic sometimes grouped together with the second-generation cephalosporin antibiotics. It is marketed under the trade name Lorabid.
Approved
Investigational
Withdrawn

Lifitegrast

Lifitegrast is a FDA approved drug for the treatment of keratoconjunctivitis sicca (dry eye syndrome). It is a tetrahydroisoquinoline derivative and lymphocyte function-associated antigen-1 ( LFA-1) antagonist that was discovered through the rational design process. The ophthalmic solution was approved in July, 2016 under the trade name Xiidra. It has...
Approved

Aripiprazole lauroxil

Aripiprazole lauroxil is a long-acting injectable atypical antipsychotic drug used in the treatment of schizophrenia in adult patients. It is a prodrug of aripiprazole, which acts as a partial agonist at the D2 and 5-HT1A receptors, and as an antagonist at the 5-HT2A receptors . Affecting about 1% of the...
Approved
Investigational

Ketoconazole

Ketoconazole is an imidazole antifungal agent used in the prevention and treatment of a variety of fungal infections.[FDA Label] It functions by preventing the synthesis of ergosterol, the fungal equivalent of cholesterol, thereby increasing membrane fluidity and preventing growth of the fungus.[A181802,T116] Ketoconazole was first approved in an oral formulation...
Approved
Investigational

Dasatinib

Dasatinib is an orally available multikinase inhibitor indicated for the treatment of Philadelphia chromosome (Ph)-positive leukemias.[A2224,L45171] Ph is a chromosomal abnormality found in patients with chronic myelogenous leukemia (CML) and acute lymphocytic leukemia (ALL), where the ABL tyrosine kinase and the breakpoint cluster region (BCR) gene transcribe the chimeric protein...
Approved
Investigational

Niclosamide

Niclosamide is an antihelminthic used for the treatment of tapeworm infections. Helminths (worms) are multicellular organisms that infect very large numbers of humans and cause a broad range of diseases. Over 1 billion people are infected with intestinal nematodes, and many millions are infected with filarial nematodes, flukes, and tapeworms....
Approved
Investigational
Vet approved

Phloxine B

Phloxine B (commonly known simply as phloxine, also known as D&C RED NO. 28) is a color additive which is used both as an inactive ingredient to provide color to products, or as a colorant in dental disclosing tablets. These tablets allow patients to visualise areas where more brushing and...
Approved

Levetiracetam

Levetiracetam is a drug within the pyrrolidine class that is used to treat various types of seizures stemming from epileptic disorders. It was first approved for use in the United States in 1999 and is structurally and mechanistically unrelated to other anti-epileptic drugs (AEDs).[L8606,L8600,L8615] Levetiracetam possesses a wide therapeutic index[L8615,A185918]...
Approved
Matched Products: … Levetiracetam in Sodium Chloride …

Cetrorelix

Cetrorelix is a man-made hormone that blocks the effects of Gonadotropin Releasing Hormone (GnRH). GnRH controls another hormone that is called luteinizing hormone (LH), which is the hormone that starts ovulation during the menstrual cycle. When undergoing hormone treatment sometimes premature ovulation can occur, leading to eggs that are not...
Approved
Investigational

Ascorbic acid

A six carbon compound related to glucose. It is found naturally in citrus fruits and many vegetables. Ascorbic acid is an essential nutrient in human diets, and necessary to maintain connective tissue and bone. Its biologically active form, vitamin C, functions as a reducing agent and coenzyme in several metabolic...
Approved
Nutraceutical
Matched Mixtures name: … Peg-3350, Sodium Sulfate, Sodium Chloride, Potassium Chloride, Sodium Ascorbate and Ascorbic Acid …

Oritavancin

Oritavancin is a glycopeptide antibiotic used for the treatment of skin infections. It was developed by The Medicines Company (acquired by Novartis). Oritavancin was initially approved by the FDA in 2014 and formulated to combat susceptible gram-positive bacteria that cause skin and skin structure infections. It boasts the option of...
Approved
Investigational

Degarelix

Degarelix is used for the treatment of advanced prostate cancer. Degarelix is a synthetic peptide derivative drug which binds to gonadotropin-releasing hormone (GnRH) receptors in the pituitary gland and blocks interaction with GnRH. This antagonism reduces luteinising hormone (LH) and follicle-stimulating hormone (FSH) which ultimately causes testosterone suppression. Reduction in...
Approved

Cupric Chloride

Cupric chloride, for injection, is a sterile, nonpyrogenic solution intended for use as an additive to solutions for Total Parenteral Nutrition (TPN).
Approved
Investigational
Matched Synonyms: … Copper chloride ... Copper(2+) chloride ... copper(II) chloride …
Matched Name: … Cupric Chloride …
Matched Description: … Cupric chloride, for injection, is a sterile, nonpyrogenic solution intended for use as an additive to …
Matched Salts name: … Cupric chloride dihydrate …
Matched Products: … Cupric Chloride …

Magnesium chloride

Magnesium chloride salts are highly soluble in water and the hydrated form of magnesium chloride can be extracted from brine or sea water.
Approved
Matched Synonyms: … Anhydrous magnesium chloride ... Magnesium chloride anhydrous …
Matched Name: … Magnesium chloride …
Matched Description: … Magnesium chloride salts are highly soluble in water and the hydrated form of magnesium chloride can …
Matched Mixtures name: … Magnesium Chloride …
Matched Salts name: … Magnesium chloride hydrate ... Magnesium chloride hexahydrate …
Matched Categories: … magnesium chloride ... magnesium chloride …
Matched Products: … Magnesium Chloride ... Magnesium Chloride 606.5mg ... MAGNESIUM CHLORIDE Dietary Supplement …

Thallous chloride

Thallous chloride (also known as Thallium(I) chloride) is a colourless solid intermediate in the isolation of thallium from its ores. It is created from the treatment of thallium(I) sulfate with hydrochloric acid. This solid crystallizes in the caesium chloride motif. It is used as a diagnostic radiopharmaceutical. It is used...
Approved
Matched Synonyms: … Thallium chloride ... Thallium(I) chloride …
Matched Name: … Thallous chloride …
Matched Description: … Thallous chloride (also known as Thallium(I) chloride) is a colourless solid intermediate in the isolation ... This solid crystallizes in the caesium chloride motif. …
Matched Products: … THALLOUS CHLORIDE (Tl201) INJECTION 37 MBq/ml …

Zinc chloride

Zinc chloride is a solution of ions indicated for use in total parenteral nutrition to maintain zinc levels and prevent deficiency syndromes. Zinc chloride was granted FDA approval before 26 June 1986.
Approved
Investigational
Matched Synonyms: … Zinc chloride …
Matched Name: … Zinc chloride …
Matched Description: … [L14189] Zinc chloride was granted FDA approval before 26 June 1986.[L14189] ... Zinc chloride is a solution of ions indicated for use in total parenteral nutrition to maintain zinc …
Matched Mixtures name: … Benzocaine, Menthol, Zinc Chloride ... Benzocaine, Menthol, Zinc Chloride ... Benzocaine, Menthol, Zinc Chloride …
Matched Categories: … zinc chloride …
Matched Products: … Zinc Chloride ... Perioselect Zinc Chloride Solution 1% …

Ferric chloride

Approved
Experimental
Matched Synonyms: … Iron chloride ... Iron (III) chloride ... Ferric chloride, anhydrous …
Matched Name: … Ferric chloride …
Matched Salts name: … Ferric chloride hexahydrate …

Stannous chloride

Stannous chloride is used as a source of tin in radiopharmaceutical kits. Tin reduces technetium-99m, the active radiological agent, allowing it to form a complex with phosphate-containing moeities . These complexes localize primarily in bone (40-50%) and infracted myocardium (0.01-0.02%/g of tissue) allowing for imaging of areas of altered osteogenesis...
Approved
Matched Synonyms: … Stannous chloride anhydrous ... Stannous chloride,anhydrous …
Matched Name: … Stannous chloride …
Matched Description: … Stannous chloride is used as a source of tin in radiopharmaceutical kits. …
Matched Salts name: … Stannous chloride dihydrate …

Ethyl chloride

Ethyl chloride, or chloroethane, has a chemical formula C2H5Cl. It was commonly used in the production of tetraethyllead (TEL), which is an additive for gasoline. It was also used in other commerical applications as a chemical reagent. It is still used in the treatment of cellulose to make ethylcellulose for...
Approved
Experimental
Investigational
Matched Synonyms: … Ethyl chloride …
Matched Name: … Ethyl chloride …
Matched Description: … Ethyl chloride, or chloroethane, has a chemical formula C2H5Cl. ... Ethyl chloride is used as a diagnostic tool to detect a dead tooth with nonviable pulp. …
Matched Categories: … ethyl chloride …
Matched Products: … ETHYL CHLORIDE …

Sodium chloride

Sodium chloride, also known as salt, common salt, table salt or halite, is an ionic compound with the chemical formula NaCl, representing a 1:1 ratio of sodium and chloride ions. Sodium chloride is the primary salt in seawater and in the extracellular fluid of many multicellular organisms. It is listed...
Approved
Vet approved
Matched Synonyms: … Sodium chloride …
Matched Name: … Sodium chloride …
Matched Iupac: … sodium chloride …
Matched Description: … chemical formula NaCl, representing a 1:1 ratio of sodium and chloride ions. ... Sodium chloride, also known as salt, common salt, table salt or halite, is an ionic compound with the ... Sodium chloride is the primary salt in seawater and in the extracellular fluid of many multicellular …
Matched Mixtures name: … Potassium Chloride in Dextrose and Sodium Chloride ... Potassium Chloride in Dextrose and Sodium Chloride ... Potassium Chloride in Dextrose and Sodium Chloride …
Matched Categories: … sodium chloride ... sodium chloride ... sodium chloride …
Matched Products: … Sodium Chloride ... Sodum Chloride ... Sodium chloride …

Colestilan chloride

Colestilan is an ingredient in the EMA-withdrawn product BindRen.
Approved
Investigational
Withdrawn
Matched Synonyms: … Colestilan chloride …
Matched Name: … Colestilan chloride …

Strontium chloride Sr-89

Strontium chloride (Sr-89), initially FDA-approved in 1993, is used as a paliative therapeutic option to help relieve the pain from bone metastases. Strontium chloride is mainly used in cases of metastatic castrate-resistant prostate cancer. Bone metastases is a common and severe complication presented in advanced stages of the disease. It...
Approved
Investigational
Matched Synonyms: … Strontium (89Sr) chloride ... Strontium-89 chloride ... Strontium chloride Sr 89 …
Matched Name: … Strontium chloride Sr-89 …
Matched Description: … Strontium chloride is mainly used in cases of metastatic castrate-resistant prostate cancer. ... Strontium chloride (Sr-89), initially FDA-approved in 1993, is used as a paliative therapeutic option …
Matched Categories: … strontium (89Sr) chloride …
Matched Products: … STRONTIUM CHLORIDE Sr-89 …
Displaying drugs 176 - 200 of 1455 in total