Quinolizines

Name
Quinolizines
Accession Number
DBCAT001626
Description
Not Available
Drugs
DrugDrug Description
TetrabenazineA vesicular monoamine transporter 2 (VMAT) inhibitor used for the management of chorea associated with Huntington's Disease.
SparteineSparteine is a plant alkaloid derived from Cytisus scoparius and Lupinus mutabilis which may chelate calcium and magnesium. It is a sodium channel blocker so it falls under the category...
ValbenazineA vesicular monoamine transporter 2 inhibitor used to treat tardive dyskinesia.
ORM-12741ORM-12741 has been used in trials studying the basic science and treatment of Alzheimer's Disease.
DeutetrabenazineA vesicular monoamine transporter 2 inhibitor used for the symptomatic treatment of chorea in Huntington's disease and tardive dyskinesia.
Drugs & Drug Targets
DrugTargetType
TetrabenazineSynaptic vesicular amine transportertarget
TetrabenazineCytochrome P450 2D6enzyme
TetrabenazineDopamine D2 receptortarget
TetrabenazineCarbonyl reductase [NADPH] 1enzyme
SparteineCytochrome P450 2D6enzyme
Valbenazinevesicular monoamine transporter 2 (VMAT2)target
ValbenazineCytochrome P450 2D6enzyme
ValbenazineCytochrome P450 3A4enzyme
ValbenazineCytochrome P450 3A5enzyme
DeutetrabenazineSynaptic vesicular amine transportertarget
DeutetrabenazineCarbonyl reductase [NADPH] 1enzyme
DeutetrabenazineCarbonyl reductase [NADPH] 3enzyme
DeutetrabenazineCytochrome P450 2D6enzyme
DeutetrabenazineCytochrome P450 1A2enzyme
DeutetrabenazineCytochrome P450 3A5enzyme
DeutetrabenazineCytochrome P450 3A4enzyme