Alcohol Withdrawal Delirium (DBCOND0003708)

Identifiers

Synonyms

Delirium Tremens (DTs) / Delirium tremens / Alcohol withdrawal delirium / Alcohol withdrawal delirium (disorder)

Associated Data

Indicated Drugs and Targets

Drug	Description	Targets
Diazepam	A long-acting benzodiazepine with rapid onset commonly used to treat panic disorders, severe anxiety, alcohol withdrawal, and seizures.	Cytochrome P450 3A4enzyme Albumincarrier Cytochrome P450 2C9enzyme Cytochrome P450 2C19enzyme Cytochrome P450 3A5enzyme Cytochrome P450 3A7enzyme ATP-dependent translocase ABCB1transporter Cytochrome P450 2B6enzyme Prostaglandin G/H synthase 1enzyme Cytochrome P450 2C18enzyme Cytochrome P450 2C8enzyme GABA(A) Receptortarget GABA(A) Receptor Benzodiazepine Binding Sitetarget Translocator proteintarget
Lorazepam	A short-acting benzodiazepine commonly used to treat panic disorders, severe anxiety, and seizures.	UDP-glucuronosyltransferase 2B15enzyme GABA(A) Receptortarget GABA(A) Receptor Benzodiazepine Binding Sitetarget Translocator proteintarget

Clinical Trials

Identifier	Title	Drug(s)	Purpose	Phase	Status
NCT03470168	Hyperbaric Oxygenation in Treatment of Alcohol Dependence Syndrome	No drug interventions	health_services_research	Not Available	completed
NCT04156464	Phenobarbital vs Ativan for Alcohol Withdrawal in the Intensive Care Unit	Lorazepam Phenobarbital	treatment	4	unknown_status
NCT01362205	Dexmedetomidine (Precedex®) for Severe Alcohol Withdrawal Syndrome (AWS) and Alcohol Withdrawal Delirium (AWD)	Dexmedetomidine	treatment	4	terminated
NCT03877120	Treatment Of Alcohol Withdrawal Syndrome: Dexmedetomidine Vs Diazepam In A Hospital O'horán	Dexmedetomidine Diazepam	treatment	4	completed
NCT03586089	Phenobarbital for Severe Acute Alcohol Withdrawal Syndrome	Diazepam Phenobarbital	treatment	Not Available	terminated
NCT00597701	Treating Alcohol Withdrawal With Oral Baclofen	Baclofen Lorazepam	prevention	Not Available	completed