Hormone-Refractory Prostate Cancer (DBCOND0030169)

Identifiers

Synonyms
Hormone Refractory Prostate Cancer Disease / Hormone Refractory Prostate Cancer / Hormone-refractory prostate cancer / Castration-resistant prostate cancer / Hormone refractory prostate cancer (disorder)

Associated Data

Indicated Drugs and Targets
DrugDescriptionTargets
Epirubicin
An anthracycline topoisomerase II inhibitor used as an adjuvant to treating axillary node metastases in patients who have undergone surgical resection of primary breast cancer.
Clinical Trials
IdentifierTitleDrug(s)PurposePhaseStatus
NCT00419536
Safety of LBH589 Alone and in Combination With Intravenous Docetaxel and Prednisonetreatment1terminated
NCT00411853
Efficacy of FWGE in Combination With Hormone Therapy for the Treatment of Hormone-Refractory Prostate Cancer PatientsNo drug interventionstreatment2unknown_status
NCT02867345
PD-1 Knockout Engineered T Cells for Castration Resistant Prostate CancerNot AvailableNot Availablewithdrawn
NCT02208583
Molecular Phenotype Changes and Personalized Treatment for CRPCNot AvailableNot Availableunknown_status
NCT01260688
Cediranib Maleate With or Without Dasatinib in Patients With HRPC-Resistant to Treatment With Docetaxeltreatment2completed
NCT01083615
A Study Evaluating the Pain Palliation Benefit of Adding Custirsen to Docetaxel Retreatment or Cabazitaxel as Second Line Therapy in Men With Metastatic Castrate Resistant Prostate Cancer (mCRPC)treatment3terminated
NCT00928252
Chemotherapy Response Monitoring With 18F-choline PET/CT in Hormone Refractory Prostate Cancerdiagnostic1 / 2completed
NCT00133900
Circulating Tumor Cells and Survival in Hormone Refractory Prostate Cancer (HRPC) Patients Receiving ChemotherapyNo drug interventionsNot AvailableNot Availableunknown_status
NCT02691975
A Safety and Efficacy Study of SHR3680 in Metastatic Castration-Resistant Prostate Cancer Patientstreatment1 / 2unknown_status
NCT00571675
A Study Comparing AT-101 in Combination With Docetaxel and Prednisone Versus Docetaxel and Prednisone in Men With Chemotherapy-Naïve Metastatic Hormone Refractory Prostate Cancer (HRPC)treatment2completed
NCT01215799
Study of Bafetinib (INNO-406) as Treatment for Patients With Hormone-Refractory Prostate Cancertreatment2completed
NCT00667199
BAY88-8223, Does Response Study in HRPC Patientstreatment2completed
NCT00286806
A Study of Single-Agent AT-101 in Men With Hormone Refractory Prostate Cancertreatment1 / 2completed
NCT00510718
A Phase 1 Study of MDV3100 in Patients With Castration-Resistant (Hormone-Refractory) Prostate Cancertreatment1completed
NCT00583024
Phase II Study of Adenovirus/PSA Vaccine in Men With Hormone - Refractory Prostate CancerNo drug interventionstreatment2completed
NCT01487863
Concurrent vs. Sequential Sipuleucel-T & Abiraterone Treatment in Men With Metastatic Castrate Resistant Prostate Cancerbasic_science2completed
NCT00629525
RAD001 in Patients With Metastatic, Hormone-Refractory Prostate Cancertreatment2completed
NCT00313482
PII Trial of Docetaxel/Prednisone w/Sargramostim for HRPCtreatment2terminated
NCT00156884
A Trial of Strontium +/- Cisplatin for the Palliation of Bone Pain Secondary to Hormone Refractory Prostate Cancertreatment2completed
NCT00699751
A Phase III Study of Radium-223 Dichloride in Patients With Symptomatic Hormone Refractory Prostate Cancer With Skeletal Metastasestreatment3completed
NCT00407251
Study of Patupilone in Prostate Cancer Patients Who Progress After Hormone Therapy and Docetaxel Chemotherapytreatment2completed
NCT00987753
Study Evaluating the Safety and Tolerability of L-377202treatment1 / 2completed
NCT00069745
Satraplatin in Hormone Refractory Prostate Cancer Patients Previously Treated With One Cytotoxic Chemotherapy Regimentreatment3completed
NCT01590498
Radiotherapy vs Observation for CRPCNo drug interventionsNot AvailableNot Availableunknown_status
NCT01518283
Study of Weekly Cabazitaxel for Advanced Prostate Cancertreatment2completed
NCT00795171
Biomarker Study for Sunitinib and Docetaxel in Prostate Cancerbasic_science2unknown_status
NCT00448734
A Study of Picoplatin and Docetaxel in Subjects With Prostate Cancertreatment1 / 2unknown_status
NCT01741116
Dovitinib(TKI258) in Patients With Castration-resistant Prostate Cancertreatment2completed
NCT00493766
Safety of LBH589 Alone and in Combination With IV Docetaxel and Prednisonetreatment1terminated
NCT02955082
The BARCODE 2 Study - The Use of Genetic Profiling to Guide Prostate Cancer Treatmenttreatment2recruiting
NCT01194960
TroVax® In Subjects With Hormone Refractory Prostate Cancer (HRPC)treatment2terminated
NCT00286091
Study on Prolonging Bone Metastasis-Free Survival in Men With Hormone Refractory Prostate Cancerprevention3completed
NCT00477529
ABI-008 Trial in Patients With Hormone-refractory Prostate Cancertreatment1 / 2completed
NCT00525408
A Study of Mycobacterium w Plus Docetaxel for Hormone Refractory Metastatic Prostate Cancertreatment2terminated
NCT00906243
RNActive®-Derived Therapeutic VaccineNo drug interventionstreatment1 / 2terminated
NCT00891345
Safety Study of a Cytotoxic Lymphocytes (CTL) Based Prostate Cancer Therapytreatment1completed
NCT01631552
Study of Sacituzumab Govitecan-hziy (IMMU-132) in Adults With Epithelial Cancertreatment1 / 2completed
NCT02288936
Analyze the Predictive Value of Gene TMPRSS2-ETS in Response to Enzalutamide in Patients With Prostate Cancertreatment2completed
NCT00082134
Study of ILX651 in Patients With Hormone-Refractory Prostate Cancer Previously Treated With DocetaxelNo drug interventionstreatment2completed
NCT03658434
Palliative Radiotherapy to Dominant Symptomatic Lesion in Patients With Hormone Refractory Prostate CancerNo drug interventionstreatmentNot Availableunknown_status
NCT00201357
An Open Trial to Assess the Efficacy and Safety of Oral Thalidomide in Patients With Hormone-Refractory Prostate Cancertreatment2completed
NCT00151073
Estramustine, Docetaxel and Zoledronate Treatment in Hormone-Refractory Adenocarcinoma of the Prostatetreatment2completed
NCT01133704
Immunotherapy With APC8015 (Sipuleucel-T, Provenge) for Asymptomatic, Metastatic, Hormone-Refractory Prostate Cancertreatment3completed
NCT01422850
Safety Study of Repeated Dosing of a Cytotoxic Lymphocytes (CTL) Based Prostate Cancer Therapytreatment1completed
NCT00337077
Eribulin Mesylate in Treating Patients With Metastatic Prostate Cancer That Did Not Respond to Hormone Therapytreatment2completed
NCT00675545
A Phase II Study of Docetaxel Plus Carboplatin in Chemonaive Hormone-Refractory Prostate Cancer (HRPC) Patientstreatment2completed
NCT01020305
Temsirolimus to Reverse Androgen Insensitivity for Castration-resistant Prostate Cancertreatment1 / 2terminated
NCT01450683
Study of Itraconazole in Castrate-resistant Prostate Cancer (CRPC) Post-chemotherapytreatment2terminated
NCT05997615
Safety, Pharmacokinetics, and Preliminary Efficacy of AMX-500 in Metastatic Castration Resistant Prostate Cancer (mCRPC)No drug interventionstreatment1 / 2recruiting
NCT00570700
Trial of Dasatinib (Sprycel®) in Subjects With Hormone-refractory Prostate Cancertreatment2completed
NCT00048659
YM598 Added to Mitoxantrone/Prednisone to Control Pain in Metastatic Prostate Cancer Patients No Longer Responding to Hormone TherapyNo drug interventionstreatment2terminated
NCT03016741
Cognitive Effects of Androgen Receptor Directed Therapies for Advanced Prostate Cancersupportive_care4unknown_status
NCT00636740
Multi-Center Phase II Study to Compare MER-101 20mg Tablets to Intravenous Zometa 4mg in Male Bisphosphonate-Naive, Hormone Refractory Prostate Cancer Patientstreatment2completed
NCT03076203
Phase IB Trial of Radium-223 and Niraparib in Patients With Castrate Resistant Prostate Cancer (NiraRad)treatment1completed