Conjunctivitis, Vernal (DBCOND0034753)

Identifiers

Synonyms

Vernal keratitis / Vernal conjunctivitis / Allergic keratitis / Vernal conjunctivitis (disorder) / Vernal keratoconjunctivitis / Keratoconjunctivitis, Vernal / Vernal keratoconjunctivitis (disorder)

Associated Data

Indicated Drugs and Targets

Drug	Description	Targets
Cromoglicic acid	A medication used to treat asthma, allergic reactions of the eyes and nose, as well as other mast cell reactions.	Protein S100-Ptarget Heat shock protein HSP 90-alphatarget
Lodoxamide	An ophthalmic agent used for the treatment of the ocular disorders referred to by the terms vernal keratoconjunctivitis, vernal conjunctivitis, and vernal keratitis.	No drug targets
Medrysone	A topical glucocorticoid applied ophthalmically for the treatment of various ocular inflammatory or allergic conditions.	Corticosteroid-binding globulincarrier Glucocorticoid receptortarget Cytochrome P450 3A4enzyme Cytochrome P450 3A5enzyme Solute carrier organic anion transporter family member 1A2transporter ATP-dependent translocase ABCB1transporter Organic anion transporter 3transporter Steroid hormone receptor ERR1target Steroid hormone receptor ERR2target Estrogen-related receptor gammatarget
Tetryzoline	An alpha-adrenergic agonist used in the temporary symptomatic relief of discomfort and redness of the eyes due to minor irritations, as well as alleviate nasal congestion.	Alpha-1 adrenergic receptorstarget Alpha-2 adrenergic receptorstarget Alpha-2C adrenergic receptortarget

Clinical Trials

Identifier	Title	Drug(s)	Purpose	Phase	Status
NCT00328653	Efficacy and Tolerance of Nova22007 Versus Vehicle in Patients With Vernal Keratoconjunctivitis (VKC)	Cyclosporine	Not Available	2 / 3	completed
NCT05038241	HORMONES IN VERNAL KERATOCONJUNCTIVITIS	No drug interventions	Not Available	Not Available	completed
NCT03186755	Clinical Evaluation of Hylo-Dual Versus Patanol in Children With Seasonal Allergic Conjunctivitis	Ectoine Hyaluronic acid Olopatadine	treatment	4	recruiting