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eye discomfort (DBCOND0094620)
Identifiers
Synonyms
Ocular discomfort
Associated Data
Indicated Drugs and Targets
Drug
Description
Targets
Boric acid
No FDA- or EMA-approved therapeutic indications on its own.
No drug targets
Hyaluronic acid
A glycosaminoglycan used for the relief of joint pain, wound healing, ophthalmologic treatment, cosmetic treatment, and various other applications.
CD44 antigen
target
Intercellular adhesion molecule 1
target
Hyaluronan mediated motility receptor
target
Neurocan core protein
target
Versican core protein
target
Complement component 1 Q subcomponent-binding protein, mitochondrial
target
Hyaluronan and proteoglycan link protein 1
target
Hyaluronan and proteoglycan link protein 3
target
Hyaluronan-binding protein 2
target
Layilin
target
Stabilin-2
target
Tumor necrosis factor-inducible gene 6 protein
target
Interphotoreceptor matrix proteoglycan 2
target
Intracellular hyaluronan-binding protein 4
target
Hyaluronidase enzymes
enzyme
ATP-binding cassette sub-family C member 5
transporter
Lymphatic vessel endothelial hyaluronic acid receptor 1
target
Polysorbate 80
It is used as a solubilizer, antimicrobial preservative and disinfectant .
No drug targets
Tetryzoline
An alpha-adrenergic agonist used in the temporary symptomatic relief of discomfort and redness of the eyes due to minor irritations, as well as alleviate nasal congestion.
Alpha-1 adrenergic receptors
target
Alpha-2 adrenergic receptors
target
Alpha-2C adrenergic receptor
target
Clinical Trials
Not Available