- Accession Number
- DBCAT000355 (DBCAT003007)
A group of tetraterpenes, with four terpene units joined head-to-tail. Biologically active members of this class are used clinically in the treatment of severe cystic ACNE; PSORIASIS; and other disorders of keratinization.
Drug Drug Description Acitretin An oral retinoid used in the treatment of severe psoriasis. Alitretinoin A vitamin A derivative used to treat Kaposi's sarcoma and used off label to treat chronic hand eczema and psoriasis. Tretinoin A vitamin A derivative used to treat acne vulgaris, certain types of promyelocytic leukemia, and fine wrinkles. Tazarotene An acetylenic retinoid used to treat fine wrinkles, mottled pigmentation of the skin, acne vulgaris, and plaque psoriasis. Isotretinoin A retinoid used to treat severe recalcitrant acne. Vitamin A A vitamin important for retinal function that is used clinically to correct vitamin A deficiency. Etretinate For the treatment of severe psoriasis in adults. 4-Oxoretinol Not Available Fenretinide Investigated for use/treatment in macular degeneration. Ro 12-7310 Not Available Zuretinol acetate Zuretinol acetate has been used in trials studying the treatment of Impaired Dark Adaptation, RP (Retinitis Pigmentosa), Retinitis Pigmentosa (RP), and LCA (Leber Congenital Amaurosis). Motretinide Not Annotated 13-cis-12-(3'-Carboxyphenyl)retinoic acid Not Annotated Adapalene A third-generation topical retinoid with anti-comedogenic, comedolytic, and anti-inflammatory properties used to treat acne vulgaris in adolescents and adults. Bexarotene A retinoid drug used for cutaneous manifestations of T-cell lymphoma in patients who have not responded well to previous systemic therapy. Anhydrovitamin A Not Available Trifarotene A topical retinoid indicated for the treatment of acne vulgaris. N-Ethylretinamide N-Ethylretinamide is the ethylamide of all-trans B-retinoic acid. Palovarotene A selective agonist of retinoic acid receptor gamma (RARγ) used to reduce heterotopic ossification in patients with Fibrodysplasia Ossificans Progressiva (FOP).
- Drugs & Drug Targets