Retinoids
- Name
- Retinoids
- Accession Number
- DBCAT000355 (DBCAT003007)
- Description
A group of tetraterpenes, with four terpene units joined head-to-tail. Biologically active members of this class are used clinically in the treatment of severe cystic ACNE; PSORIASIS; and other disorders of keratinization.
- Drugs
Drug Drug Description 13-cis-12-(3'-Carboxyphenyl)retinoic acid Not Annotated 4-Oxoretinol Not Available Acitretin An oral retinoid used in the treatment of severe psoriasis. Adapalene A third-generation topical retinoid with anti-comedogenic, comedolytic, and anti-inflammatory properties used to treat acne vulgaris in adolescents and adults. Alitretinoin A vitamin A derivative used to treat Kaposi's sarcoma and used off label to treat chronic hand eczema and psoriasis. Anhydrovitamin A Not Available Bexarotene A retinoid drug used for cutaneous manifestations of T-cell lymphoma in patients who have not responded well to previous systemic therapy. Etretinate For the treatment of severe psoriasis in adults. Fenretinide Investigated for use/treatment in macular degeneration. Isotretinoin A retinoid used to treat severe recalcitrant acne. Motretinide Not Annotated N-Ethylretinamide N-Ethylretinamide is the ethylamide of all-trans B-retinoic acid. Palovarotene A selective agonist of retinoic acid receptor gamma (RARĪ³) used to reduce heterotopic ossification in patients with Fibrodysplasia Ossificans Progressiva (FOP). Ro 12-7310 Not Available Tazarotene An acetylenic retinoid used to treat fine wrinkles, mottled pigmentation of the skin, acne vulgaris, and plaque psoriasis. Transcrocetinate Investigated for use/treatment in cancer/tumors (unspecified), hemorrhage, hypoxia, respiratory failure, and strokes. Tretinoin A vitamin A derivative used to treat acne vulgaris and certain types of promyelocytic leukemia, as well as various skin conditions in over-the-counter medications. Trifarotene A topical retinoid indicated for the treatment of acne vulgaris. Vitamin A A vitamin important for retinal function that is used clinically to correct vitamin A deficiency. Zuretinol acetate Zuretinol acetate has been used in trials studying the treatment of Impaired Dark Adaptation, RP (Retinitis Pigmentosa), Retinitis Pigmentosa (RP), and LCA (Leber Congenital Amaurosis). - Drugs & Drug Targets