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Citric Acid Cycle
smpdb.ca/view/SMP0000057MetabolicThe citric acid cycle is named after citrate or citric acid, a tricarboxylic acid that is both consumed and regenerated through this pathway. … as amino acid synthesis and oxidative phosphorylation (OxPhos).
Enzymes: Succinyl-CoA ligase [GDP-forming] subunit beta, mitochondrial, Succinyl-CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrialFatty Acid Biosynthesis
smpdb.ca/view/SMP0000456MetabolicThe production of palmitic acid can be summarized as the successive addition of two carbons to an initial acetyl moiety primer. After 7 cycles palimitic acid is released. … The biosynthesis of fatty acids primarily occurs in liver and lactating mammary glands.
Drugs: Biotin · Acetoacetic acid · Butenoic Acid · Malonic acid · (R)-3-hydroxytetradecanoic acid · Lauric acid +8 moreEnzymes: Fatty acid synthaseGadoteric acid Metabolism
smpdb.ca/view/SMP0126924MetabolicGadoteric acid is indicated for intravenous use with magnetic resonance imaging (MRI) in brain (intracranial), spine and associated tissues in adult and pediatric patients (2 years of age and older) to … Gadoteric acid is a diagnostic contrast agent used with magnetic resonance imaging to provide contrast enhancement for intracranial and spinal lesions with abnormal blood brain barrier or abnormal vascularity
Drugs: Gadoteric acidSelenoamino Acid Metabolism
smpdb.ca/view/SMP0000029Metabolic3-phosphate (lysophosphatidic acid). … These 2 products combine to produce a cardiolipin and an ethanolamine. The L-1 phosphatidyl-glycerol can also interact with cardiolipin synthase resulting in a glycerol and a cardiolipin.
Arachidonic Acid Metabolism
smpdb.ca/view/SMP0000075MetabolicThis pathway describes the production and subsequent metabolism of arachidonic acid, an omega-6 fatty acid. … The newly formed eicosanoids may also exit the cell of origin and bind to G-protein-coupled receptors present on nearby neurons or glial cells.
Gastric Acid Production
smpdb.ca/view/SMP0000589PhysiologicalThis digestive fluid is formed in the stomach (specifically by the parietal cells) and is mainly composed of hydrochloric acid (HCl). … HCl and/or KCl, which are both constituents of stomach acid.
Gadoxetic acid Metabolism
smpdb.ca/view/SMP0126873MetabolicGadoxetic acid is a gadolinium-based contrast agent used in magnetic resonance imaging (MRI) to help characterize lesions in the liver. … The water protons in the vicinity are disrupted such that the change the proton density and spin characteristics are detected and visualized by a device.
Drugs: Gadoxetic acidTranexamic Acid Action Pathway
smpdb.ca/view/SMP0000287Drug actionTranexamic acid is a synthetic version of an amino acid found in the body called lysine that plays a role in antifibrinolytic processes. It is used to stop bleeding and hemorrhaging in patients. … Tranexamic acid inhibits plasminogen.
Lysophosphatidic Acid LPA1 Signalling
smpdb.ca/view/SMP0063746SignalingLysophosphatidic acid (LPA) is a water-soluble phospholipid derivative and a potent signalling molecule that binds to six known lysophosphatidic acid receptors (LPARs), named LPA1-LPA6. … LPC, LPE, LPS) into LPA via autotaxin (ATX/Enpp2) and (2) the conversion of phosphatidic acid (PA) into LPA via phospholipase A1 or A2 (PLA1/PLA2).
Enzymes: Lysophosphatidic acid receptor 1