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Displaying results 21 - 30 of 2175 in total
  1. Pathway

    Intracellular Signalling Through Adenosine Receptor A2b and Adenosine

    smpdb.ca/view/SMP0000321
    Signaling

    Adenosine is thought to play a role in the pathophysiology of asthma. Stimulation of A2B can induce production of interleukin-8 mast cells. The adenosine receptor A2b activates G(s) proteins which lead to the activation of adenylyl cycla...

    Drugs: ATP · Adenosine · Magnesium cation · Zinc · Cyclic adenosine monophosphate · Pyrophosphoric acid
  2. Pathway

    Ziconotide NMDA and Substance P Receptor Pain Inhibition Action Pathway

    smpdb.ca/view/SMP0126347
    Drug action

    such as intrathecal morphine and systemic analgesics. … This causes downstream nociceptive neuronal activity and pain perception. Substance P and CGRP both also induce inflammation, further exasperating chronic pain.

    Drugs: Glutamic acid · Calcium · Sar9, Met (O2)11-Substance P · Ziconotide
    Enzymes: Voltage-dependent L-type calcium channel subunit beta-4, Voltage-dependent L-type calcium channel subunit beta-1
  3. Pathway

    Metabolism and Physiological Effects of N-alpha-Acetyl-L-arginine

    smpdb.ca/view/SMP0125530
    Metabolic

    Arginnosuccinate is synthesized from citrulline and aspartic acid by the enzyme argininosuccinate synthase. That is catalyzed by argininosuccinate lyase to produce arginine and fumaric acid. … In the blood it works as a uremic toxin to cause kidney damage, cardiovascular disease and neurological deficits.

    Drugs: Pyridoxal phosphate · Arginine · Aspartic acid · Ornithine · L-Glutamine · Adenosine phosphate +10 more
    Enzymes: Calcium-binding mitochondrial carrier protein Aralar1
  4. Indication

    Calcium and Vitamin D Deficiencies

    go.drugbank.com/conditions/DBCOND0077928
    Drugs: Calcium Phosphate · Calcium carbonate · Cholecalciferol
    Synonyms: Calcium and Vitamin D Deficiencies
  5. Indication

    Combined Vitamin B1 and B12 deficiency

    go.drugbank.com/conditions/DBCOND0134819
    Drugs: Cyanocobalamin
    Synonyms: Combined Vitamin B1 and B12 deficiency
  6. Pathway

    Magnesium Salicylate Action Pathway

    smpdb.ca/view/SMP0000698
    Drug action

    Magnesium Salicylate can block prostaglandin synthesis by the action of inhibition of prostaglandin G/H synthase 1 and 2. … Magnesium Salicylate is a nonsteroidal anti-inflammatory drug. It can be used to treat mild to moderate muscular pain such as headaches, general back pain and other joint pain.

    Drugs: Glutamic acid · Glutathione · Dinoprostone · Calcium · Magnesium cation · Magnesium salicylate +5 more
  7. Pathway

    Magnesium Sulfate Action Pathway

    smpdb.ca/view/SMP0126350
    Drug action

    Magnesium sulfate is a drug used to treat convulsions during pregnancy, nephritis in children, magnesium deficiency, and tetany. … Excitation and contraction are uncoupled, which decreases the frequency and force of contractions. Magnesium is the second most plentiful cation of the intracellular fluids.

    Drugs: Choline · ATP · Magnesium sulfate · Potassium cation · Calcium · Magnesium cation +3 more
    Enzymes: Voltage-dependent L-type calcium channel subunit beta-4, Voltage-dependent L-type calcium channel subunit beta-1
  8. Indication

    Zinc Deficiency

    go.drugbank.com/conditions/DBCOND0037140
    Drugs: Ferrous gluconate · Magnesium · Zinc · Zinc cation · Zinc gluconate · Zinc orotate
    Synonyms: Zinc low, Zinc Deficiency
  9. Indication

    Manganese deficiency

    go.drugbank.com/conditions/DBCOND0166359
    Drugs: Manganese cation
    Synonyms: Manganese deficiency, Manganese deficiency (disorder)
  10. Drug

    Ascorbic acid

    go.drugbank.com/drugs/DB00126
    ApprovedInvestigationalNutraceutical

    It is found naturally in citrus fruits and many vegetables. Ascorbic acid is an essential nutrient in human diets, and necessary to maintain connective tissue and bone. … Its biologically active form, vitamin C, functions as a reducing agent and coenzyme in several metabolic pathways. Vitamin C is considered an antioxidant.

    Mixtures: CALCIUM AND MAGNESIUM PLUS C,POTASSIUM AND ZINC TABLET, Calcium Magnesium Avec Vitamine CCategories: ascorbic acid (vit C) and calcium, Alimentary Tract and Metabolism