| Somatostatin receptor type 1 | Humans | Receptor for somatostatin with higher affinity for somatostatin-14 than -28. This receptor is coupled via pertussis t... more | 4 | Details |
| Somatostatin receptor type 2 | Humans | Receptor for somatostatin-14 and -28. This receptor is coupled via pertussis toxin sensitive G proteins to inhibition... more | 27 | Details |
| Somatostatin receptor type 3 | Humans | Receptor for somatostatin-14 and -28. This receptor is coupled via pertussis toxin sensitive G proteins to inhibition... more | 6 | Details |
| Somatostatin receptor type 4 | Humans | Receptor for somatostatin-14. The activity of this receptor is mediated by G proteins which inhibits adenylyl cyclase... more | 3 | Details |
| Somatostatin receptor type 5 | Humans | Receptor for somatostatin 28 and to a lesser extent for somatostatin-14. The activity of this receptor is mediated by... more | 13 | Details |
| Sorbitol dehydrogenase | Humans | Polyol dehydrogenase that catalyzes the reversible NAD(+)-dependent oxidation of various sugar alcohols. Is mostly ac... more | 3 | Details |
| Sorcin | Humans | Calcium-binding protein that modulates excitation-contraction coupling in the heart. Contributes to calcium homeostas... more | 3 | Details |
| Sortase B | Staphylococcus aureus (strain NCTC 8325) | Transpeptidase that anchors surface proteins to the cell wall. Recognizes and modifies its substrate by proteolytic c... more | 2 | Details |
| Sorting nexin-3 | Humans | Phosphoinositide-binding protein required for multivesicular body formation. Specifically binds phosphatidylinositol ... more | 1 | Details |
| SPARC | Humans | Appears to regulate cell growth through interactions with the extracellular matrix and cytokines. Binds calcium and c... more | 3 | Details |
| Spectrin beta chain, non-erythrocytic 1 | Humans | Fodrin, which seems to be involved in secretion, interacts with calmodulin in a calcium-dependent manner and is thus ... more | 2 | Details |
| Spermidine synthase | Humans | Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM). Has a strong ... more | 1 | Details |
| Spermidine synthase | Plasmodium falciparum (isolate 3D7) | Not Available | 1 | Details |
| Spermidine/putrescine-binding periplasmic protein | Escherichia coli (strain K12) | Required for the activity of the bacterial periplasmic transport system of putrescine and spermidine. Polyamine bindi... more | 1 | Details |
| Spermidine/spermine N(1)-acetyltransferase | Bacillus subtilis (strain 168) | Involved in the protection against polyamine toxicity by regulating their concentration. Could also be involved in th... more | 2 | Details |
| Spermine oxidase | Humans | Flavoenzyme which catalyzes the oxidation of spermine to spermidine. Can also use N(1)-acetylspermine and spermidine ... more | 2 | Details |
| Spermine synthase | Humans | Catalyzes the production of spermine from spermidine and decarboxylated S-adenosylmethionine (dcSAM) | 1 | Details |
| Sphingolipid delta(4)-desaturase DES1 | Humans | Has sphingolipid-delta-4-desaturase activity. Converts D-erythro-sphinganine to D-erythro-sphingosine (E-sphing-4-eni... more | 1 | Details |
| Sphingolipid delta(4)-desaturase/C4-monooxygenase DES2 | Humans | Bifunctional enzyme which acts both as a sphingolipid delta(4)-desaturase and a sphingolipid C4-monooxygenase | 1 | Details |
| Sphingomyelin phosphodiesterase | Humans | Converts sphingomyelin to ceramide. Exists as two enzymatic forms that arise from alternative trafficking of a single... more | 8 | Details |
| Sphingomyelin phosphodiesterase 2 | Humans | Catalyzes, at least in vitro, the hydrolysis of sphingomyelin to form ceramide and phosphocholine. Also hydrolyzes 1-... more | 1 | Details |
| Sphingomyelin phosphodiesterase 3 | Humans | Catalyzes the hydrolysis of sphingomyelin to form ceramide and phosphocholine. Ceramide mediates numerous cellular fu... more | 2 | Details |
| Sphingomyelin phosphodiesterase 4 | Humans | Catalyzes the hydrolysis of membrane sphingomyelin to form phosphorylcholine and ceramide. It has a relevant role in ... more | 2 | Details |
| Sphingosine 1-phosphate receptor 1 | Humans | G protein-coupled receptor for the bioactive lysosphingolipid sphingosine 1-phosphate (S1P) that seems to be coupled ... more | 14 | Details |
| Sphingosine 1-phosphate receptor 2 | Humans | Receptor for the lysosphingolipid sphingosine 1-phosphate (S1P). S1P is a bioactive lysophospholipid that elicits div... more | 2 | Details |