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A non-essential amino acid present abundantly throughout the body and is involved in many metabolic processes. It is synthesized from glutamic acid and ammonia. It is the principal carrier of nitrogen in the body and is an important energy source for many cells. An oral formulation of L-glutamine was approved...
Approved
Investigational
Nutraceutical
Matched Synonyms: … Glutamic acid amide ... Glutamic acid 5-amide ... L-glutamic acid γ-amide …
Matched Iupac: … (2S)-2-amino-4-carbamoylbutanoic acid
Matched Description: … It is synthesized from glutamic acid and ammonia. ... A non-essential amino acid present abundantly throughout the body and is involved in many metabolic processes ... It is the principal carrier of nitrogen in the body and is an important energy source for many cells. …
Matched Salts name: … Glutamine sodium
Matched Categories: … Amino Acids and Derivatives ... Alimentary Tract and Metabolism ... Amino Acids, Peptides, and Proteins …
Brilliant Blue G is used in an ophthalmic solution for staining the internal limiting membrane (ILM) of the eye during ophthalmic procedures.[A188841,A188844] This membrane is thin and translucent, making it difficult to identify during eye surgeries that require high levels of visual accuracy. Brilliant blue G, like its name, imparts...
Approved
Matched Synonyms: … Acid Blue 90 ... Acid Blue 90 …
Matched Iupac: … sodium 3-({[4-({4-[(4-ethoxyphenyl)amino]phenyl}[(1E,4E)-4-{ethyl[(3-sulfonatophenyl)methyl]iminiumyl …
Matched Description: … [A188841,A188844] This membrane is thin and translucent, making it difficult to identify during eye surgeries …
Matched Categories: … Indicators and Reagents …
Sulbactam is a beta (β)-lactamase inhibitor and a derivative of the basic penicillin nucleus. When given in combination with β-lactam antibiotics, sulbactam produces a synergistic effect as it blocks the enzyme responsible for drug resistance by hydrolyzing β-lactams.
Approved
Matched Synonyms: … Penicillanic acid sulfone ... Penicillanic acid 1,1-dioxide ... (2S,5R)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid 4,4-dioxide …
Matched Iupac: … (2S,5R)-3,3-dimethyl-4,4,7-trioxo-4lambda6-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
Matched Description: … Sulbactam is a beta (β)-lactamase inhibitor and a derivative of the basic penicillin nucleus. …
Matched Mixtures name: … Ampicillin Sodium and Sulbactam Sodium ... Ampicillin Sodium and Sulbactam Sodium ... Ampicillin Sodium and Sulbactam Sodium
Matched Salts name: … Sulbactam sodium
Furosemide is a potent loop diuretic that acts on the kidneys to ultimately increase water loss from the body. It is an anthranilic acid derivative. Furosemide is used for edema secondary to various clinical conditions, such as congestive heart failure exacerbation, liver failure, renal failure, and high blood pressure. It...
Approved
Vet approved
Matched Synonyms: … 2-Furfurylamino-4-chloro-5-sulfamoylbenzoic acid ... 4-Chloro-5-sulfamoyl-N-furfuryl-anthranilic acid ... 4-Chloro-N-furfuryl-5-sulfamoylanthranilic acid
Matched Iupac: … 4-chloro-2-{[(furan-2-yl)methyl]amino}-5-sulfamoylbenzoic acid
Matched Description: … It is an anthranilic acid derivative. ... Furosemide has a fast onset and short duration of action and has been used safely and effectively in ... both pediatric and adult patients. …
Matched Salts name: … Furosemide sodium
Matched Categories: … Sodium Potassium Chloride Symporter Inhibitors ... furosemide and potassium ... furosemide and potassium-sparing agents ... High-Ceiling Diuretics and Potassium-Sparing Agents …
Butabarbital, or Butisol, is a fast onset barbiturate with short duration of action compared to other barbiturates.[A201977,L13613] This makes butabarbital a useful drug for treating severe insomnia and pre-operative anxiety.[A201977,L13613] Butabarbital is less commonly used in recent years, as more patients are typically prescribed benzodiazepines. Its short duration of action...
Approved
Illicit
Matched Synonyms: … 5-sec-butyl-5-ethylbarbituric acid ... 5-ethyl-5-(1-methylpropyl)barbituric acid
Matched Description: … [A201977,L13613] This makes butabarbital a useful drug for treating severe insomnia and pre-operative …
Matched Mixtures name: … Phenazopyridine Hydrochloride, Hyoscyamine Hydrobromide, and Butabarbital …
Matched Salts name: … Butabarbital sodium
Matched Categories: … Hypnotics and Sedatives …
Matched Products: … Butisol Sodium ... Butisol Sodium Tab 30mg ... Butisol Sodium Tab 15mg …
Methyl nicotinate is the methyl ester of DB00627 that is used as an active ingredient as a rubefacient in over-the-counter topical preparations indicated for muscle and joint pain. The action of methyl nicotinate as a rubefacient is thought to involve peripheral vasodilation. For veterinary purposes, methyl nicotinate is used to...
Approved
Matched Synonyms: … Nicotinic acid, methyl ester ... 3-pyridinecarboxylic acid methyl ester …
Matched Description: … muscle and joint pains [F64]. ... an active ingredient as a rubefacient in over-the-counter topical preparations indicated for muscle and ... methyl nicotinate is used to treat respiratory diseases, vascular disorders, rheumatoid arthritis, and
An anti-inflammatory agent, structurally related to the salicylates and non-steroidal anti-inflammatory drugs like acetylsalicylic acid, which is active in inflammatory bowel disease . Although demonstrably effective in treating and maintaining remission for ulcerative colitis, mesalazine has historically faced a number of issues regarding its lack of stability as a pharmaceutical...
Approved
Matched Synonyms: … 5-aminosalicylic acid ... m-Aminosalicylic acid
Matched Iupac: … 5-amino-2-hydroxybenzoic acid
Matched Description: … drugs like acetylsalicylic acid, which is active in inflammatory bowel disease [A174022]. ... An anti-inflammatory agent, structurally related to the salicylates and non-steroidal anti-inflammatory ... Although demonstrably effective in treating and maintaining remission for ulcerative colitis, mesalazine …
Matched Products: … Ntp-5-aminosalicylic Acid
Phenylalanine is an essential aromatic amino acid that is a precursor of melanin, dopamine, noradrenalin (norepinephrine), and thyroxine.
Approved
Investigational
Nutraceutical
Matched Synonyms: … (S)-2-Amino-3-phenylpropionic acid ... (S)-alpha-Amino-beta-phenylpropionic acid
Matched Iupac: … (2S)-2-amino-3-phenylpropanoic acid
Matched Description: … ] (norepinephrine), and [thyroxine]. ... Phenylalanine is an essential aromatic amino acid that is a precursor of melanin, [dopamine], [noradrenalin …
Matched Mixtures name: … Aminosyn II and Dextrose ... Aminosyn II and Dextrose ... Travasol Amino Acid Inj 8.5% …
Matched Salts name: … Phenylalanine sodium
Matched Categories: … Amino Acids, Peptides, and Proteins …
An important compound functioning as a component of the coenzyme NAD. Its primary significance is in the prevention and/or cure of blacktongue and pellagra. Most animals cannot manufacture this compound in amounts sufficient to prevent nutritional deficiency and it therefore must be supplemented through dietary intake.
Approved
Investigational
Matched Synonyms: … Nicotinic acid amide …
Matched Description: … Its primary significance is in the prevention and/or cure of blacktongue and pellagra. ... Most animals cannot manufacture this compound in amounts sufficient to prevent nutritional deficiency and
Matched Mixtures name: … Calcipotriene 0.005% / Diclofenac Sodium 3% / Hyaluronic Acid Sodium Salt 2% / Niacinamide 2% ... Hyaluronic Acid Sodium Salt 1% / Niacinamide 4% / Tacrolimus 0.1% ... Hyaluronic Acid Sodium Salt 0.5% / Niacinamide 4% / Tretinoin 0.1% …
Matched Categories: … Alimentary Tract and Metabolism …
Matched Products: … Dr.g Lock and More A-clear Mask ... P8 Tone - Up and Brightening CreamEX ... HANSKIN BiO FILL PEP MASK Firming and Moisture …
Nedosiran is an RNA interference targeting hepatic lactate dehydrogenase, the enzyme responsible for the conversion of glyoxylate to oxalate. Oxalate, particularly calcium oxalate, precipitation is the main cause of kidney stones formation; therefore, blocking the production of oxalate can help alleviate renal symptoms. Nedosiran was approved by the FDA on...
Approved
Investigational
Matched Synonyms: … DCR-PHXC free acid
Matched Description: … older and adults with primary hyperoxaluria type 1 (PH1) and relatively preserved kidney function. ... sup>, 2023, under the brand name RIVFLOZA to lower urinary oxalate levels in children 9 years of age and ... This approval is based on the favorable results from the pivotal phase 2 PHYOXTM2 and interim …
Matched Salts name: … Nedosiran sodium
Originally approved by the FDA in 1989, omeprazole is a proton-pump inhibitor, used to treat gastric acid-related disorders. These disorders may include gastroesophageal reflux disease (GERD), peptic ulcer disease, and other diseases characterized by the oversecretion of gastric acid. This drug was the first clinical useful drug in its class,...
Approved
Investigational
Vet approved
Matched Description: … characterized by the oversecretion of gastric acid. ... Omeprazole is generally effective and well-tolerated, promoting its popular use in children and adults ... Originally approved by the FDA in 1989, omeprazole is a _proton-pump inhibitor_, used to treat gastric acid-related …
Matched Mixtures name: … Omeprazole and Sodium Bicarbonate ... Omeprazole and Sodium Bicarbonate ... Omeprazole and Sodium Bicarbonate
Matched Salts name: … Omeprazole sodium
Matched Categories: … Acid Reducers ... Gastric Acid Lowering Agents ... Drugs for Acid Related Disorders ... Alimentary Tract and Metabolism ... Omeprazole and enantiomer …
Matched Products: … OMEPRAZOLE SODIUM ... Acid Reducer ... OMEPRAZOLE SODIUM MONOHYDRATE …
Dasabuvir is a direct acting antiviral medication used as part of combination therapy to treat chronic Hepatitis C, an infectious liver disease caused by infection with Hepatitis C Virus (HCV). HCV is a single-stranded RNA virus that is categorized into nine distinct genotypes, with genotype 1 being the most common...
Approved
Matched Synonyms: … Sodium 3-(3-tert-butyl-4-methoxy-5-{6­ [(methylsulfonyl)amino]naphthalene-2-yl}phenyl)-2,6-dioxo-3,6 …
Matched Description: … [DB00503] for genotype 1b and with [DB00811] for genotype 1a of Hepatitis C [L852]. ... categorized into nine distinct genotypes, with genotype 1 being the most common in the United States, and ... recommendation published in 2016, the American Association for the Study of Liver Diseases (AASLD) and
Matched Salts name: … Dasabuvir sodium ... Dasabuvir sodium monohydrate …
Matched Categories: … dasabuvir, ombitasvir, paritaprevir and ritonavir …
A semisynthetic cephalosporin antibiotic which can be administered intravenously or by suppository. The drug is highly resistant to a broad spectrum of beta-lactamases and is active against a wide range of both aerobic and anaerobic gram-positive and gram-negative organisms. It has few side effects and is reported to be safe...
Approved
Withdrawn
Matched Synonyms: … syn-7-(2-(2-Amino-4-thiazolyl)-2-methoxyiminoacetamido)-3-cephem-4-carboxylic acid ... Amino-thiazol-4-yl)-2-methoxyimino-acetylamino]-8-oxo-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid
Matched Iupac: … 1,3-thiazol-4-yl)-2-(methoxyimino)acetamido]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
Matched Description: … It has few side effects and is reported to be safe and effective in aged patients and in patients with ... of both aerobic and anaerobic gram-positive and gram-negative organisms. ... The drug is highly resistant to a broad spectrum of beta-lactamases and is active against a wide range …
Matched Salts name: … Ceftizoxime sodium
Matched Products: … CEFTIZOXIME SODIUM
Cefalotin is a cephalosporin antibiotic.
Approved
Investigational
Vet approved
Matched Synonyms: … 7-(2-Thienylacetamido)cephalosporanic acid ... 7-(2'-thienylacetamido)cephalosporanic acid ... 3-Acetoxymethyl-7-(2-thienylacetamido)-3-cephem-4-carboxylic acid
Matched Iupac: … acetyloxy)methyl]-8-oxo-7-[2-(thiophen-2-yl)acetamido]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
Matched Salts name: … Cefalotin sodium
Cilastatin is an inhibitor of renal dehydropeptidase, an enzyme responsible for both the metabolism of thienamycin beta-lactam antibiotics as well as conversion of leukotriene D4 to leukotriene E4. Since the antibiotic, imipenem, is one such antibiotic that is hydrolyzed by dehydropeptidase, cilastatin is used in combination with imipenem to prevent...
Approved
Investigational
Matched Synonyms: … (L)-7-(2-Amino-2-carboxy-ethylsulfanyl)-2-[(2,2-dimethyl-cyclopropanecarbonyl)-amino]-hept-2-enoic acid ... (R)-2-Amino-2-carboxy-ethylsulfanyl)-2-[((S)-2,2-dimethyl-cyclopropanecarbonyl)-amino]-hept-2-enoic acid
Matched Iupac: … )-7-{[(2R)-2-amino-2-carboxyethyl]sulfanyl}-2-{[(1S)-2,2-dimethylcyclopropyl]formamido}hept-2-enoic acid
Matched Mixtures name: … IMIPENEM MONOHYDRATE - CILASTATIN SODIUM ... IMIPENEM MONOHYDRATE / CILASTATIN SODIUM ... Imipenem and Cilastatin …
Matched Salts name: … Cilastatin sodium
Matched Categories: … imipenem and cilastatin ... imipenem, cilastatin and relebactam …
Matched Products: … Cilastatin Sodium Sterile …
Dorzolamide is a non-bacteriostatic sulfonamide derivative and topical carbonic anhydrase (CA) inhibitor that treats elevated intraocular pressure (IOP) associated with open-angle glaucoma and ocular hypertension. It works by blocking an enzyme in the ciliary process that regulates ion balance and fluid pressure in the eyes. Unlike oral CA inhibitors, dorzolamide...
Approved
Matched Synonyms: … 6S)-4-ethylamino-6-methyl-7,7-dioxo-4,5,6,7-tetrahydro-7lambda*6*-thieno[2,3-b]thiopyran-2-sulfonic acid ... 4-Ethylamino-6-methyl-7,7-dioxo-4,5,6,7-tetrahydro-7lambda*6*-thieno[2,3-b]thiopyran-2-sulfonic acid ... 4-ethylamino-6-methyl-7,7-dioxo-4,5,6,7-tetrahydro-7lambda6-thieno[2,3-b]thiopyran-2-sulfonic acid amide …
Matched Description: … [A1303] Unlike oral CA inhibitors, dorzolamide has negligible effects of acid-base or electrolyte disturbances ... and other systemic adverse effects. ... Dorzolamide is a non-bacteriostatic sulfonamide derivative [A1304] and topical carbonic anhydrase (CA …
Matched Mixtures name: … Dorzolamide and Timolol ... Dorzolamide and Timolol ... Dorzolamide HCl and Timolol Maleate …
Matched Categories: … Antiglaucoma Preparations and Miotics ... Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics …
Propylparaben is used in allergenic testing.
Approved
Experimental
Matched Synonyms: … 4-Hydroxybenzoic acid propyl ester ... 4-Hydroxybenzoic acid, propyl ester ... p-Hydroxybenzoic acid propyl ester …
Matched Salts name: … Propylparaben sodium
An antibiotic similar to flucloxacillin used in resistant staphylococci infections.
Approved
Investigational
Matched Synonyms: … 6β-(5-methyl-3-phenylisoxazol-4-yl)penicillanic acid ... 5-methyl-3-phenylisoxazol-4-yl)carbonyl]amino}-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
Matched Iupac: … dimethyl-6-(5-methyl-3-phenyl-1,2-oxazole-4-amido)-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
Matched Salts name: … Oxacillin sodium ... Oxacillin sodium monohydrate …
Iodipamide is a water-soluble radiographic contrast media for cholecystography and intravenous cholangiography.
Approved
Matched Synonyms: … 3,3'-(adipoyldiimino)bis(2,4,6-triiodobenzoic acid) …
Matched Iupac: … 3-{5-[(3-carboxy-2,4,6-triiodophenyl)carbamoyl]pentanamido}-2,4,6-triiodobenzoic acid
Matched Description: … Iodipamide is a water-soluble radiographic contrast media for cholecystography and intravenous cholangiography …
Matched Salts name: … Iodipamide sodium
Montelukast was first approved for clinical use by the US FDA in 1998 as Merck's brand name Singulair. The medication is a member of the leukotriene receptor antagonist (LTRA) category of drugs.[L6301,L6304,L6307,L6310,L6325,L6328,L6331] Although capable of demonstrating effectiveness, the use of such LTRAs like montelukast is typically in addition to or...
Approved
Matched Synonyms: … quinolinyl)ethenyl)phenyl)-3-(2-(1-hydroxy-1-methylethyl)phenyl)propyl)thio)methyl)cyclopropaneacetic acid ... quinolinyl)ethenyl] phenyl]-3-[2-(1-hydroxy-1-methylethyl)phenyl]propyl]sulfanyl]methyl]cyclopropaneacetic acid
Matched Iupac: … chloroquinolin-2-yl)ethenyl]phenyl}-3-[2-(2-hydroxypropan-2-yl)phenyl]propyl]sulfanyl}methyl)cyclopropyl]acetic acid
Matched Description: … has since become available as a generic and as a brand name product. ... montelukast to elicit neuropsychiatric effects like agitation, hallucinations, suicidal behaviour, and ... L6325,L6328,L6331] the drug still sees extensive use worldwide via millions of prescriptions annually and
Matched Salts name: … Montelukast sodium
Matched Categories: … Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … Montelukast Sodium ... Montelukast sodium ... MONTELUKAST SODIUM
Approved
Investigational
Matched Synonyms: … Sulfuric acid, dipotassium salt …
Matched Mixtures name: … Sodium Sulfate, Potassium Sulfate and Magnesium Sulfate ... Sodium Sulfate, Potassium Sulfate and Magnesium Sulfate ... Sodium Sulfate, Potassium Sulfate and Magnesium Sulfate …
Secobarbital (marketed by Eli Lilly and Company under the brand names Seconal and Tuinal) is a barbiturate derivative drug with anaesthetic, anticonvulsant, sedative and hypnotic properties. It is commonly known as quinalbarbitone in the United Kingdom.
Approved
Vet approved
Matched Synonyms: … 5-allyl-5-(1-methylbutyl)barbituric acid
Matched Description: … Secobarbital (marketed by Eli Lilly and Company under the brand names Seconal and Tuinal) is a barbiturate ... derivative drug with anaesthetic, anticonvulsant, sedative and hypnotic properties. …
Matched Salts name: … Secobarbital sodium
Matched Categories: … Hypnotics and Sedatives …
Matched Products: … Seconal Sodium ... Seconal Sodium Pulvule 240 0.1gm …
Sulindac is a nonsteroidal anti-inflammatory drug (NSAID) of the arylalkanoic acid class that is marketed by Merck under the brand name Clinoril. Like other NSAIDs, it may be used in the treatment of acute or chronic inflammatory conditions. Sulindac is a prodrug, derived from sulfinylindene, that is converted in vivo...
Approved
Investigational
Matched Synonyms: … cis-5-Fluoro-2-methyl-1-((p-methylsulfinyl)benzylidene)indene-3-acetic acid ... (Z)-5-Fluoro-2-methyl-1-((p-(methylsulfinyl)phenyl)methylene)-1H-indene-3-acetic acid ... cis-5-Fluoro-2-methyl-1-((4-(methylsulfinyl)phenyl)methylene)-1H-indene-3-acetic acid
Matched Iupac: … 2-[(1Z)-5-fluoro-1-[(4-methanesulfinylphenyl)methylidene]-2-methyl-1H-inden-3-yl]acetic acid
Matched Description: … Sulindac is a nonsteroidal anti-inflammatory drug (NSAID) of the arylalkanoic acid class that is marketed ... is thought to primarily mediate its action by inhibiting prostaglandin synthesis by inhibiting COX-1 and ... levels of the compound without inducing gastrointestinal effects, where the drug is excreted in the bile and
Matched Salts name: … Sulindac sodium
Matched Categories: … Acetic Acid Derivatives and Related Substances ... Antiinflammatory and Antirheumatic Products ... Antiinflammatory and Antirheumatic Products, Non-Steroids …
Hypochlorite is an ion composed of chlorine and oxygen with the chemical formula ClO−. Being unstable in the pure form, hypochlorite is most commonly used for bleaching, disinfectation, and water treatment purposes in its salt form, sodium hypochlorite. Hypochlorite is often used as a chemical reagent for chlorination and oxidation...
Approved
Matched Description: … water treatment purposes in its salt form, sodium hypochlorite. ... Hypochlorite is an ion composed of chlorine and oxygen with the chemical formula ClO−. ... Hypochlorite is often used as a chemical reagent for chlorination and oxidation reactions. …
Matched Salts name: … Sodium hypochlorite …
Matched Categories: … Antiseptics and Disinfectants ... Sodium Compounds ... sodium hypochlorite …
Matched Products: … SUPERCLEAN Micro Acid Hypochlorite Disinfectant ... Sodium hypochlorite disinfectant ... (Qiqing) Sodium Hypochlorite Disinfectant …
Indometacin, or indomethacin, is a non-steroidal anti-inflammatory drug (NSAID) with anti-inflammatory, analgesic, and antipyretic properties. NSAIDs consist of agents that are structurally unrelated; the NSAID chemical classification of indometacin is an indole-acetic acid derivative with the chemical name 1- (p-chlorobenzoyl)25-methoxy-2-methylindole-3-acetic acid. The pharmacological effect of indometacin is not fully understood,...
Approved
Investigational
Matched Synonyms: … 1-(p-chlorobenzoyl)-5-methoxy-2-methylindole-3-acetic acid ... {1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl-1H-indol-3-yl}acetic acid
Matched Iupac: … 2-[1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl]acetic acid
Matched Description: … Drug Administration in 1965, [A486] along with other acetic acid derivatives such as [diclofenac] and ... thromboxane biosynthesis via the arachidonic acid (AA) pathway. ... derivative with the chemical name 1- (p-chlorobenzoyl)25-methoxy-2-methylindole-3-acetic acid. …
Matched Salts name: … Indomethacin sodium
Matched Categories: … Acetic Acid Derivatives and Related Substances ... indometacin and antiinfectives ... Antiinflammatory and Antirheumatic Products ... Topical Products for Joint and Muscular Pain ... Antiinflammatory and Antirheumatic Products, Non-Steroids …
Displaying drugs 226 - 250 of 655 in total