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Displaying drugs 2701 - 2725 of 9554 in total

Tolevamer

Sodium polystyrene sulfonate is a medication used to treat abnormally high potassium levels. It may be taken orally or by rectum, as an enema, and functions as a potassium-binding resin in the intestines. It is also an effective topical microbicide and spermicide, inhibiting the genital transfection of, among others, HIV.
Approved
Investigational
Matched Description: … It is also an effective topical microbicide and spermicide, inhibiting the genital transfection of, among …
Matched Categories: … Drugs for Treatment of Hyperkalemia and Hyperphosphatemia …

Raltegravir

Raltegravir is an antiretroviral drug produced by Merck & Co., used to treat HIV infection. It received approval by the U.S. Food and Drug Administration (FDA) on 12 October 2007, the first of a new class of HIV drugs, the integrase inhibitors, to receive such approval.
Approved
Matched Description: … Food and Drug Administration (FDA) on 12 October 2007, the first of a new class of HIV drugs, the integrase …
Matched Categories: … Antivirals used in combination for the treatment of HIV infections …

Dextromethorphan

Dextromethorphan is a levorphanol derivative and codeine analog commonly used as a cough suppressant and also a drug of abuse. Although similar in structure to other opioids, it has minimal interaction with opioid receptors. Dextromethorphan was granted FDA approval before 3 December 1957.[A215412,L14997]
Approved
Matched Description: … is a levorphanol derivative and codeine analog commonly used as a cough suppressant and also a drug of …
Matched Mixtures name: … Regular Strength Cold Medication(daytime R.) ... Hot Lemon Relief for Symptoms Of Cough and Cold ... Hot Liquid Relief for Symptoms Of Cold and Cough …
Matched Categories: … Combined Inhibitors of Serotonin/Norepinephrine Reuptake ... Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …

Rituximab

Rituximab is a genetically engineered chimeric murine/human monoclonal antibody directed against the CD20 antigen found on the surface of normal and malignant B lymphocytes. The antibody is an IgG1 kappa immunoglobulin containing murine light and heavy-chain variable region sequences and human constant region sequences , [FDA label]. It was originally...
Approved
Matched Description: … engineered chimeric murine/human monoclonal antibody directed against the CD20 antigen found on the surface of ... patients with B-cell Non-Hodgkin's Lymphoma (NHL) [L4811], however, has now been approved for a variety of …
Matched Categories: … CHOP-R chemotherapy regimen ... CD20 (Clusters of Differentiation 20) inhibitors …

Sparfloxacin

Sparfloxacin is a fluoroquinolone antibiotic indicated for bacterial infections. Sparfloxacin exerts its antibacterial activity by inhibiting DNA gyrase, a bacterial topoisomerase. DNA gyrase is an essential enzyme which controls DNA topology and assists in DNA replication, repair, deactivation, and transcription.
Approved
Investigational
Withdrawn
Matched Categories: … Drugs for Treatment of Tuberculosis …

Polythiazide

A thiazide diuretic with actions and uses similar to those of hydrochlorothiazide. (From Martindale, The Extra Pharmacopoeia, 30th ed, p826)
Approved
Matched Description: … A thiazide diuretic with actions and uses similar to those of hydrochlorothiazide. …
Matched Mixtures name: … Renese-R …
Matched Categories: … combinations of sulfonamides …

Venlafaxine

Venlafaxine is an antidepressant and a serotonin and norepinephrine reuptake inhibitor (SNRI). Its active metabolite, desvenlafaxine, works by blocking the reuptake of serotonin and norepinephrine, which are key neurotransmitters in mood regulation. Venlafaxine is officially approved to treat major depressive disorder (MDD), generalized anxiety disorder (GAD), social anxiety disorder, and...
Approved
Matched Description: … for the management of neuropathic pain (although there is only minimal evidence of efficacy for this ... Its active metabolite, [desvenlafaxine], works by blocking the reuptake of serotonin and norepinephrine ... [L43030] The immediate formulation of the drug, marketed as Effexor, was first approved by the FDA in …
Matched Categories: … Combined Inhibitors of Serotonin/Norepinephrine Reuptake ... Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …
Matched Products: … VENLAFAXIN AXUNIO 37.5MG R …

Doravirine

Doravirine is an HIV-1 non-nucleoside reverse transcriptase inhibitor (NNRTI) intended to be administered in combination with other antiretroviral medicines.[L12729,L4562] Doravirine is available by itself or as a combination product of doravirine (100 mg), lamivudine (300 mg), and tenofovir disoproxil fumarate (300 mg). Doravirine is formally indicated for the treatment of...
Approved
Investigational
Matched Description: … treatments available for the management of HIV-1 infection. ... [L12729,L4562] Doravirine is available by itself or as a combination product of doravirine (100 mg), ... [L4562] Doravirine is formally indicated for the treatment of HIV-1 infection in adult patients with …
Matched Categories: … Antivirals used in combination for the treatment of HIV infections …

Fluorescein

A phthalic indicator dye that appears yellow-green in normal tear film and bright green in a more alkaline medium, such as the aqueous humor, and is used therapeutically as a diagnostic aid in corneal injuries and corneal trauma. It has been approved by FDA for use in externally applied drugs...
Approved
Matched Categories: … Diagnostic Uses of Chemicals …

Fenfluramine

Dravet syndrome is a pediatric encephalopathy that typically manifests within the first year of life following exposure to elevated temperatures. It is characterized by recurrent pharmacoresistant seizures, which increase in frequency and severity with disease progression. Concomitantly with these seizures, patients typically display delayed development and neurocognitive impairment.[A214694, A214709, A214712,...
Approved
Illicit
Investigational
Withdrawn
Matched Description: … Dravet syndrome is a pediatric encephalopathy that typically manifests within the first year of life ... in 1973 prior to its withdrawal; it was granted a new FDA approval on June 25, 2020, for treatment of …
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …

Oxiconazole

Oxiconazole is an antifungal agent that is commonly found in topical formulations. It is marketed under the brand names Oxistat and Oxistat, and is used in the treatment of various skin infections such as athlete's foot, jock itch and ringworm.
Approved
Matched Description: … It is marketed under the brand names Oxistat and Oxistat, and is used in the treatment of various skin …
Matched Categories: … combinations of imidazole derivatives …

Sulfanilamide

Sulfanilamide is a molecule containing the sulfonamide functional group attached to an aniline.
Approved
Matched Categories: … combinations of sulfonamides …

Remifentanil

Remifentanil (marketed by Abbott as Ultiva) is a potent ultra short-acting synthetic opioid given to patients during surgery for pain relief and adjunctive to an anaesthetic. Remifentanil is a specific mu-type-opioid receptor agonist which means it reduces sympathetic nervous system tone, and causes respiratory depression and analgesia.
Approved
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …

Sulfamethoxazole

Sulfamethoxazole is a bacteriostatic sulfonamide antibiotic that interferes with folic acid synthesis in susceptible bacteria. It is generally given in combination with trimethoprim, which inhibits a sequential step in bacterial folic acid synthesis - these agents work synergistically to block two consecutive steps in the biosynthesis of nucleic acids and...
Approved
Matched Description: … [L11830] In this combination, sulfamethoxazole is useful for the treatment of a variety of bacterial ... infections, including those of the urinary, respiratory, and gastrointestinal tracts. ... acid synthesis - these agents work synergistically to block two consecutive steps in the biosynthesis of …
Matched Mixtures name: … SOLASTEM(R) TABLETAS ... MEDIPRIM F (R) TABLETA ... MEDIPRIM F (R) TABLETA …
Matched Categories: … combinations of sulfonamides ... Drugs for Treatment of Tuberculosis …

Flibanserin

Flibanserin is the first drug to be approved for hypoactive sexual desire disorder (HSDD) in premenopausal women by the FDA in August 2015. It was originally developed as an antidepressant medication by Boehringer Ingelheim, but showed lack of efficacy in trials and was further developed as a hypoactive sexual disorder...
Approved
Investigational
Matched Description: … It was originally developed as an antidepressant medication by Boehringer Ingelheim, but showed lack of ... Flibanserin's mechanism of action is attributed to its high affinity for 5-HTA1 and 5-HTA2 receptors, ... displaying agonist activity on 5-HTA1 and antagonist on 5-HTA2, resulting in lowering of serotonin in …
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …

Cinchocaine

A local anesthetic of the amide type now generally used for surface anesthesia. It is one of the most potent and toxic of the long-acting local anesthetics and its parenteral use is restricted to spinal anesthesia. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1006)
Approved
Vet approved
Matched Description: … It is one of the most potent and toxic of the long-acting local anesthetics and its parenteral use is ... A local anesthetic of the amide type now generally used for surface anesthesia. …
Matched Categories: … Agents for Treatment of Hemorrhoids and Anal Fissures for Topical Use …

Thiamylal

A barbiturate that is administered intravenously for the production of complete anesthesia of short duration, for the induction of general anesthesia, or for inducing a hypnotic state. (From Martindale, The Extra Pharmacopoeia, 30th ed, p919)
Approved
Vet approved
Matched Description: … A barbiturate that is administered intravenously for the production of complete anesthesia of short duration ... , for the induction of general anesthesia, or for inducing a hypnotic state. …
Matched Categories: … combinations of barbiturates …

Dexfenfluramine

Dexfenfluramine, also marketed under the name Redux, is a serotoninergic anorectic drug. For a fairly limited time during the middle of the nineties, the US FDA had approved it for use in managing weight loss. However, following multiple concerns about the cardiovascular side-effects of the drug, such approval was withdrawn.
Approved
Illicit
Investigational
Withdrawn
Matched Description: … However, following multiple concerns about the cardiovascular side-effects of the drug, such approval ... For a fairly limited time during the middle of the nineties, the US FDA had approved it for use in managing …
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …

Norgestrel

Norgestrel is synthetic steroidal progestin that is used in combination with ethinyl estradiol for oral contraception. Norgestrel is composed of a racemic mixture of two stereoisomers, dextronorgestrel and levonorgestrel. However, only the levorotary enantiomer (levonorgestrel) is biologically active.
Approved
Matched Description: … Norgestrel is composed of a racemic mixture of two stereoisomers, dextronorgestrel and levonorgestrel …
Matched Categories: … Sex Hormones and Modulators of the Genital System …

Lithium carbonate

Lithium has been used to treat manic episodes since the 19th century . Though it is widely used, its mechanism of action is still unknown[FDA Label][A14585,A176642,A176651,L5843]. Lithium carbonate has a narrow therapeutic range and so careful monitoring is required to avoid adverse effects[FDA Label].
Approved
Matched Description: … Though it is widely used, its mechanism of action is still unknown[FDA Label][A14585,A176642,A176651, …
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …

Nefazodone

Nefazodone hydrochloride (trade name Serzone) is an antidepressant drug marketed by Bristol-Myers Squibb. Its sale was discontinued in 2003 in some countries, due to the small possibility of hepatic (liver) injury. Drug-induced hepatic injuries were associated with an risk of elevated need for a liver transplant, or even death, with...
Approved
Withdrawn
Matched Description: … On May 20, 2004, Bristol-Myers Squibb discontinued the sale of Serzone in the United States. ... Its sale was discontinued in 2003 in some countries, due to the small possibility of hepatic (liver) ... Drug-induced hepatic injuries were associated with an risk of elevated need for a liver transplant, or …
Matched Categories: … Combined Inhibitors of Serotonin/Norepinephrine Reuptake ... Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …

Dantron

Withdrawn from the Canadian, US, and UK markets in 1998 due to genotoxicity.
Approved
Investigational
Withdrawn

Pseudoephedrine

Pseudoephedrine is structurally related to ephedrine but exerts a weaker effect on the sympathetic nervous system.[A188820,A188823] Both drugs naturally occur in in ephedra plant which have a history of use in traditional Eastern medicine and were first researched in the west in 1889. The decongestant effect of pseudoephedrine was described...
Approved
Matched Description: … [A188823] The decongestant effect of pseudoephedrine was described in dogs in 1927.[A188823] ... [A188820,A188823] Both drugs naturally occur in in ephedra plant which have a history of use in traditional …
Matched Mixtures name: … DOSITAN (R) TABLETAS ... Regular Strength Cold Medication(daytime R.) ... FLURINOL(R) D COMPRIMIDOS DE LIBERACION MODIFICADA …
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …

Sulfamethizole

A sulfathiazole antibacterial agent.
Approved
Investigational
Vet approved
Matched Categories: … combinations of sulfonamides …

Zotepine

Zotepine, with the formula (2-chloro-11-(2-dimethyl-amino-ethoxy)-dibenzo thiepin, is a neuroleptic drug. It was designed and synthesized by Fujisawa Pharmaceutical Co Ltd. It has been used as an antipsychotic in Japan, India and some places in Europe like UK and Germany since 1980's. Zotepine was never approved by the FDA. In 1993,...
Approved
Investigational
Withdrawn
Matched Description: … inactive drug substance (Status I, Type II) and in 1995 the FDA studied the manufacturing procedures of ... In the EMA, by 2015 it was under pharmacovigilance studies for the potential treatment of acute renal ... [L1082] When the analysis of antipsychotics was retaken in 2016 by the FDA, zotepine did not reach the …
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …
Displaying drugs 2701 - 2725 of 9554 in total