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Displaying drugs 251 - 275 of 1338 in total

Fingolimod

Multiple sclerosis, or MS, is a devastating inflammatory disease that often progresses and causes severe neurological, physical, and cognitive effects. Fingolimod is a sphingosine 1-phosphate receptor modulator for the treatment of relapsing-remitting multiple sclerosis. It was developed by Novartis and initially approved by the FDA in 2010. Fingolimod was also...
Approved
Investigational
Matched Description: … [A176474] Fingolimod is a sphingosine 1-phosphate receptor modulator for the treatment of relapsing-remitting …
Matched Categories: … Sphingosine 1-phosphate Receptor Modulator ... Sphingosine 1 Phosphate Receptor Modulators ... Sphingosine-1-phosphate (S1P) receptor modulators …

Nitrendipine

Nitrendipine is a calcium channel blocker with marked vasodilator action. It is an effective antihypertensive agent and differs from other calcium channel blockers in that it does not reduce glomerular filtration rate and is mildly natriuretic, rather than sodium retentive.
Approved
Investigational
Matched Description: … does not reduce glomerular filtration rate and is mildly natriuretic, rather than sodium retentive. ... Nitrendipine is a calcium channel blocker with marked vasodilator action. ... It is an effective antihypertensive agent and differs from other calcium channel blockers in that it …
Matched Categories: … Calcium Channel Blockers ... ACE Inhibitors and Calcium Channel Blockers ... Calcium-Regulating Hormones and Agents ... Selective Calcium Channel Blockers With Mainly Vascular Effects …

Lercanidipine

Lercanidipine is a calcium channel blocker of the dihydropyridine class. It is sold under various commercial names including Zanidip.
Approved
Investigational
Matched Description: … Lercanidipine is a calcium channel blocker of the dihydropyridine class. …
Matched Categories: … Calcium Channel Blockers ... ACE Inhibitors and Calcium Channel Blockers ... Calcium-Regulating Hormones and Agents ... Angiotensin II receptor blockers (ARBs) and calcium channel blockers ... Selective Calcium Channel Blockers With Mainly Vascular Effects …

Amifampridine

Amifampridine, or 3,4-diaminopyridine (3,4-DAP), is a quaternary ammonium compound that blocks presynaptic potassium channels, and subsequently prolongs the action potential and increases presynaptic calcium concentrations . It was first discovered in Scotland in the 1970s and its clinical effectiveness for neuromuscular disorders, including Lambert–Eaton myasthenic syndrome (LEMS), has been investigated...
Approved
Investigational
Matched Description: … Amifampridine phosphate is a more stable salt that serves as an active ingredient of EMA-approved Firdapse ... , leading to decreased presynaptic calcium levels and reduced quantal release of acetylcholine, which ... presynaptic potassium channels, and subsequently prolongs the action potential and increases presynaptic calcium …
Matched Salts name: … Amifampridine phosphate …

Alendronic acid

Alendronic acid is a second generation bisphosphonate that is used for the treatment of some forms of osteoperosis and Paget's disease[FDA Label][A959,A203111]. It functions by preventing resorption of bone[FDA Label] .
Approved
Matched Salts name: … Alendronate calcium ... Alendronate sodium ... Alendronate sodium anhydrous …
Matched Categories: … alendronic acid, calcium and colecalciferol, sequential …
Matched Products: … Alendronate Sodium ... Ag-alendronate Sodium ... Jamp Alendronate Sodium …

Clevidipine

Clevidipine is a dihydropyridine L-type calcium channel blocker that is selective for vascular smooth muscle and is indicated for blood pressure reduction when oral therapy is not an option.
Approved
Investigational
Matched Description: … Clevidipine is a dihydropyridine L-type calcium channel blocker that is selective for vascular smooth …
Matched Categories: … Calcium Channel Blockers ... Calcium-Regulating Hormones and Agents ... Calcium Channel Blockers (Dihydropyridine) ... Selective Calcium Channel Blockers With Mainly Vascular Effects …

Carvedilol

Carvedilol is a racemic mixture where the S(-) enantiomer is both a beta and alpha-1 adrenoceptor blocker, and the R(+) enantiomer is an alpha-1 adrenoceptor blocker.[L7889,L7892] It is currently used to treat heart failure, left ventricular dysfunction, and hypertension.[L7889,L7892] The dual action of carvedilol is advantageous in combination therapies as...
Approved
Investigational
Matched Salts name: … Carvedilol phosphate …
Matched Categories: … Calcium Channel Blockers ... Calcium-Regulating Hormones and Agents …
Matched Products: … Carvedilol Phosphate …

Doxycycline

Doxycycline is a broad-spectrum antibiotic synthetically derived from oxytetracycline. It is a second-generation tetracycline that was first discovered in 1967. Second-generation tetracyclines exhibit lesser toxicity than first-generation tetracyclines. Doxycycline is used to treat a wide variety of gram-positive and gram-negative bacterial infections. It is also used to treat acne and...
Approved
Investigational
Vet approved
Matched Salts name: … Doxycycline calcium …
Matched Products: … Vibramycin Calcium …

Pitavastatin

Pitavastatin, also known as the brand name product Livalo, is a lipid-lowering drug belonging to the statin class of medications. By inhibiting the endogenous production of cholesterol within the liver, statins lower abnormal cholesterol and lipid levels and ultimately reduce the risk of cardiovascular disease. More specifically, statin medications competitively...
Approved
Matched Salts name: … Pitavastatin calcium ... Pitavastatin sodium …
Matched Products: … Pitavastatin Calcium …

Ziconotide

Ziconotide (also known as SNX-111) is a neurotoxic peptide derived from the cone snail Conus magus comprising 25 amino acids with three disulphide bonds.[A202835, L13389] Other such peptides, collectively termed conotoxins, exist, and some have shown efficacy in binding specific subsets of calcium channels; ziconotide is used in part because...
Approved
Matched Description: … [L13389] To date, ziconotide is the only calcium channel blocking peptide approved for use by the FDA ... collectively termed conotoxins, exist, and some have shown efficacy in binding specific subsets of calcium ... used to manage severe chronic pain refractory to other methods, through its ability to inhibit N-type calcium …
Matched Categories: … Calcium Channel Blockers ... Calcium Channels, N-Type ... Calcium-Regulating Hormones and Agents ... N-Calcium Channel Receptor Antagonists …

Cinnarizine

First synthesized by Janssen Pharmaceuticals in 1955, cinnarizine is an anti-histaminic drug mainly used for the control of vestibular disorders and motion sickness. Cinnarizine is a specific calcium channel blocker that primarily works on the central vestibular system to interfere with the signal transmission between vestibular apparatus of the inner...
Approved
Investigational
Matched Description: … Cinnarizine is a specific calcium channel blocker that primarily works on the central vestibular system ... Cinnarizine could be also viewed as a nootropic drug because of its vasorelaxating abilities (due to calcium …
Matched Categories: … Calcium Channel Blockers ... Calcium-Regulating Hormones and Agents …

Patiromer

Patiromer is a powder for suspension in water for oral administration, approved in the U.S. as Veltassa in October, 2015. Patiromer is supplied as patiromer sorbitex calcium which consists of the active moiety, patiromer, a non-absorbed potassium-binding polymer, and a calcium-sorbitol counterion. Each gram of patiromer is equivalent to a...
Approved
Investigational
Matched Description: … The chemical name for patiromer sorbitex calcium is cross-linked polymer of calcium 2-fluoroprop-2-enoate ... non-absorbed potassium-binding polymer, and a calcium-sorbitol counterion. ... Patiromer is supplied as patiromer sorbitex calcium which consists of the active moiety, patiromer, a …
Matched Salts name: … Patiromer sorbitex calcium …

Magnesium

Magnesium is classified as an alkaline earth metal and has 2 hydration shells. The element can be found in abundance in the hydrosphere and in mineral salts such as dolomite and magnesium carbonate. Common dietary sources of magnesium include nuts (cashews, peanuts, almonds), beans, bananas, apples, carrots, broccoli, and leafy...
Approved
Experimental
Investigational
Matched Description: … element can be found in abundance in the hydrosphere and in mineral salts such as dolomite and magnesium carbonate …
Matched Mixtures name: … Calcium Magnesium Sulfur Silicon - Tab ... Active Calcium Plus Magnesium, Vitamin D and Silicon ... Actical Plus Calcium-magnesium-vitamin D3-silicon Chewable …

Mecobalamin

Approved
Investigational
Matched Mixtures name: … Levomefolate Calcium-Pyridoxal Phosphate-Mecobalamin ... Levomefolate Calcium Pyridoxal-5 Phosphate Mecobalamin Algal ... Levomefolate Calcium, Pyridoxal 5-phosphate, Methylcobalamin and Schizochytrium DHA Oil …

Zofenopril

Zofenopril is employed as both a cardioprotective and anti-hypertensive agent. It is an angiotensin-converting enzyme (ACE) inhibitor.
Approved
Matched Salts name: … Zofenopril calcium …

Gallium nitrate

Gallium nitrate is a nitrate salt of DB14524, a heavy metal that has been used as a diagnostic agent. Gallium nitrate is reported to possess antiresorptive and hypocalcemic effects on bone. GANITE, a product of gallium nitrate previously used to treat cancer-related hypercalcemia, was discontinued from marketing in the US...
Approved
Investigational
Matched Categories: … Calcium Resorption Inhibitor ... Calcium-Regulating Hormones and Agents …

Sulfacetamide

An anti-infective agent that is used topically to treat skin infections and orally for urinary tract infections.
Approved
Matched Mixtures name: … Sulfacetamide Sodium and Prednisolone Sodium Phosphate ... Sulfacetamide Sodium and Prednisolone Sodium Phosphate ... Sulfacetamide Sodium and Prednisolone Sodium Phosphate …
Matched Salts name: … Sulfacetamide sodium …
Matched Products: … Sulfacetamide Sodium ... Sodium Sulfacetamide ... Sodium sulfacetamide …

Magnesium gluconate

Magnesium gluconate is a magnesium salt of gluconate. It demonstrates the highest oral bioavailability of magnesium salts and is used as a mineral supplement. Magnesium is ubiquitous in the human body, and is naturally present in many foods, added to other food products, available as a dietary supplement and used...
Approved
Investigational

Sitagliptin

Sitagliptin is an oral dipeptidyl peptidase-4 (DPP-4) inhibitor used in conjunction with diet and exercise to improve glycemic control in patients with type 2 diabetes mellitus[FDA label,A2260,A2255,A2256]. The effect of this medication leads to glucose dependent increases in insulin and decreases in glucagon to improve control of blood sugar[FDA label,A2255]....
Approved
Investigational
Matched Mixtures name: … Sitagliptin Phosphate/Metformin Hydrochloride ... JANUMET 50/850MG (SITAGLIPTIN PHOSPHATE/METFORMIN HCI) ... JANUMET 50/500MG (SITAGLIPTIN PHOSPHATE/METFORMIN HCI) …
Matched Salts name: … Sitagliptin phosphate …

D-glucose

Glucose is a simple sugar (monosaccharide) generated during phosynthesis involving water, carbon and sunlight in plants. It is produced in humans via hepatic gluconeogenesis and breakdown of polymeric glucose forms (glycogenolysis). It circulates in human circulation as blood glucose and acts as an essential energy source for many organisms through...
Approved
Investigational
Vet approved
Matched Mixtures name: … DIANEAL Low Calcium with Dextrose ... DIANEAL Low Calcium with Dextrose ... Haemonetics Anticoagulant Citrate Phosphate Double Dextrose Solution (CP2D) …

Siponimod

Siponimod, also known as Mayzent, by Novartis, is a new drug formulated for the management of Multiple Sclerosis (MS). It was approved by the FDA on March 26, 2019 and by Health Canada on February 20, 2020. This drug is considered a sphingosine-1-phosphate (S1P) receptor modulator and is thought to...
Approved
Investigational
Matched Description: … [L12171] This drug is considered a _sphingosine-1-phosphate (S1P) receptor modulator_ and is thought …
Matched Categories: … Sphingosine 1-phosphate Receptor Modulator ... Sphingosine 1 Phosphate Receptor Modulators ... Sphingosine-1-phosphate (S1P) receptor modulators …

Chloramphenicol succinate

Chloramphenicol succinate is an ester prodrug of chloramphenicol. Chloramphenicol is a bacteriostatic antibiotic. Use of chloramphenicol succinate and chloramphenicol has decreased due to the risk of potentially fatal blood dyscrasias. Chloramphenicol succinate was granted FDA approval on 20 February 1959.
Approved
Matched Salts name: … Chloramphenicol sodium succinate …
Matched Products: … Chloromycetin Sodium Succinate ... Chloramphenicol Sodium Succinate ... CHLORAMPHENICOL SODIUM SUCCINATE …

Glyburide

Glyburide is a second generation sulfonylurea used to treat patients with diabetes mellitus type II. It is typically given to patients who cannot be managed with the standard first line therapy, metformin. Glyburide stimulates insulin secretion through the closure of ATP-sensitive potassium channels on beta cells, raising intracellular potassium and...
Approved
Matched Description: … the closure of ATP-sensitive potassium channels on beta cells, raising intracellular potassium and calcium …

Cyanocobalamin

Cyanocobalamin (commonly known as Vitamin B12) is a highly complex, essential vitamin, owing its name to the fact that it contains the mineral, cobalt. This vitamin is produced naturally by bacteria , and is necessary for DNA synthesis and cellular energy production. Vitamin B12 has many forms, including the cyano-,...
Approved
Nutraceutical
Matched Mixtures name: … Phytofortis + Calcium A-D ... Iron Aspartate, Glycinate, Ascorbic Calcium, Vitamin B12, Calcium Threonate and Succinic Acid ... Calcium Folic Acid Plus D Chewable …

Etrasimod

Etrasimod is a synthetic next-generation selective Sphingosine 1-phosphate (S1P) receptor modulator that targets the S1P1,4,5 with no detectable activity on S1P2 and S1P3 receptors. S1P receptors are membrane-derived lysophospholipid signaling molecules that are involved in the sequestration of circulating peripheral lymphocytes in lymph nodes. Therefore, S1P receptor modulators like etrasimod...
Approved
Matched Description: … Etrasimod is a synthetic next-generation selective Sphingosine 1-phosphate (S1P) receptor modulator that …
Matched Categories: … Sphingosine-1-phosphate (S1P) receptor modulators …
Displaying drugs 251 - 275 of 1338 in total