Displaying drugs 301 - 325 of 10489 in total
Simethicone
Simethicone is a silicon based surfactant that decreases the surface tension of gastrointestinal gas bubbles to facilitate their elimination. It has a favourable safety profile as it is not systemically absorbed. Simethicone has been in use since the 1940s but was granted FDA approval in 1952.
Approved
Matched Description: … Simethicone is a silicon based surfactant that decreases the surface tension of gastrointestinal gas …
Matched Mixtures name: … MUVETT S ... MUVETT S ... GASPRID-S …
Matched Mixtures name: … MUVETT S ... MUVETT S ... GASPRID-S …
Betaine
Betaine is a methyl group donor that functions in the normal metabolic cycle of methionine. It is a naturally occurring choline derivative commonly ingested through diet, with a role in regulating cellular hydration and maintaining cell function.[A252235,A252240] Homocystinuria is an inherited disorder that leads to the accumulation of homocysteine in...
Approved
Investigational
Nutraceutical
Matched Description: … Betaine is a methyl group donor that functions in the normal metabolic cycle of methionine. ... Currently, no treatments are available to correct the genetic causes of homocystinuria. ... [A252235,A252240] Homocystinuria is an inherited disorder that leads to the accumulation of homocysteine …
Matched Mixtures name: … KORDEL`S NUTRITIME TABLET …
Matched Mixtures name: … KORDEL`S NUTRITIME TABLET …
Nabumetone
Nabumetone was originally developed as a non-acidic non-steroidal anti-inflammatory drug (NSAID).[label] It was thought to avoid trapping of the drug in the stomach by making it unable to dissociate into ions which was believed to reduce GI toxicity by limiting local action. While slightly reduced, possibly due to a degree...
Approved
Matched Description: … [label] It was thought to avoid trapping of the drug in the stomach by making it unable to dissociate ... [A179077] While slightly reduced, possibly due to a degree of cyclooxygenase-2 selectivity (COX-2), nabumetone …
Scorpion (centruroides) immune Fab2 antivenin (equine)
Centruroides (scorpion) Immune F(ab')2 (equine) is a purified preparation of immune globulin F(ab’)2 fragments that are derived from plasma of the horses immunized with venom of C. noxius, C. l. limpidus, C. l. tecomanus, and C. s. suffusus. It is intravenously administered patients with clinical signs of scorpion envenomation so...
Approved
Matched Description: … *, *C. l. tecomanus*, and *C. s. suffusus*. ... fragments that are derived from plasma of the horses immunized with venom of *C. noxius*, *C. l. limpidus ... Centruroides (scorpion) Immune F(ab')2 (equine) is a purified preparation of immune globulin F(ab’)2 …
Becaplermin
Becaplermin is produced by recombinant DNA technology by insertion of the gene for the B chain of platelet derived growth factor (PDGF) into the yeast, Saccharomyces cerevisiae. Becaplermin has a molecular weight of approximately 25 KD and is a homodimer composed of two identical polypeptide chains that are bound together...
Approved
Investigational
Matched Description: … Becaplermin is produced by recombinant DNA technology by insertion of the gene for the B chain of platelet ... Becaplermin has a molecular weight of approximately 25 KD and is a homodimer composed of two identical …
Matched Categories: … Preparations for Treatment of Wounds and Ulcers …
Matched Categories: … Preparations for Treatment of Wounds and Ulcers …
Ombitasvir
Ombitasvir is a direct acting antiviral medication used as part of combination therapy to treat chronic Hepatitis C, an infectious liver disease caused by infection with Hepatitis C Virus (HCV). HCV is a single-stranded RNA virus that is categorized into nine distinct genotypes, with genotype 1 being the most common...
Approved
Investigational
Matched Description: … class of DAAs [A19593]. ... The barrier for develoment of resistance to NS5A inhibitors is lower than that of NS5B inhibitors, another ... Lack of significant side effects and short duration of therapy is a considerable advantage over older …
Matched Categories: … Antivirals for treatment of HCV infections …
Matched Categories: … Antivirals for treatment of HCV infections …
Estetrol
Naturally or synthetically produced steroid estrogens have a wide range of pharmaceutical uses ranging from hormonal contraception to the treatment of menopausal symptoms. Estetrol (E4) is a native estrogen occurring naturally during pregnancy, but can be synthesized from a plant source and used for contraception. It is more potent and...
Approved
Investigational
Matched Description: … from hormonal contraception to the treatment of menopausal symptoms. ... Naturally or synthetically produced steroid estrogens have a wide range of pharmaceutical uses ranging ... L33179] It is more potent and is safer than the synthetic estrogen ethinylestradiol (EE2) found in 97% of …
Matched Categories: … Sex Hormones and Modulators of the Genital System …
Matched Categories: … Sex Hormones and Modulators of the Genital System …
Butorphanol
A synthetic morphinan analgesic with narcotic antagonist action. It is used in the management of severe pain.
Approved
Illicit
Vet approved
Matched Description: … It is used in the management of severe pain. …
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …
Nalbuphine
A narcotic used as a pain medication. It appears to be an agonist at kappa opioid receptors and an antagonist or partial agonist at mu opioid receptors. Nalbuphine is the only opioid analgesic that is not a controlled substance in the United States.
Approved
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …
Citalopram
Citalopram is an antidepressant belonging to the class of selective serotonin-reuptake inhibitors (SSRIs) widely used to treat the symptoms of depression. It is a racemic bicyclic phthalate derivate and is the only compound with a tertiary amine and 2 nitrogen-containing metabolites among all SSRIs.[A261316,A14720] Citalopram enhances serotonergic transmission through the...
Approved
Matched Description: … SSRIs) widely used to treat the symptoms of depression. ... Citalopram is an antidepressant belonging to the class of selective _serotonin-reuptake inhibitors_ ( ... [A261316]
Citalopram was approved by the FDA in 1998 for the treatment of depression in adults 18 …
Matched Categories: … Combined Inhibitors of Serotonin/Norepinephrine Reuptake ... Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …
Matched Categories: … Combined Inhibitors of Serotonin/Norepinephrine Reuptake ... Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …
Tolcapone
Tolcapone is a drug that inhibits the enzyme catechol-O-methyl transferase (COMT). It is used in the treatment of Parkinson's disease as an adjunct to levodopa/carbidopa medication. It is a yellow, odorless, non-hygroscopic, crystalline compound. Tolcapone is associated with a risk of hepatotoxicity.
Approved
Withdrawn
Matched Description: … Tolcapone is associated with a risk of hepatotoxicity. ... It is used in the treatment of Parkinson's disease as an adjunct to levodopa/carbidopa medication. …
Etelcalcetide
Etelcalcetide is a calcimimetic drug for the treatment of secondary hyperparathyroidism in patients undergoing hemodialysis. Etelcalcetide was approved (trade name Parsabiv) for the treatment of secondary hyperparathyroidism (HPT) in adult patients with chronic kidney disease (CKD) on hemodialysis in February, 2017.
Approved
Investigational
Matched Description: … Etelcalcetide was approved (trade name Parsabiv) for the treatment of secondary hyperparathyroidism ( ... Etelcalcetide is a calcimimetic drug for the treatment of secondary hyperparathyroidism in patients undergoing …
Sodium sulfide
Sodium sulfide is a chemical compound with a chemical formula Na2S. Sodium sulfide is used in the pulp and paper industry, water treatment, textile industry, and various chemical manufacturing processes including the production of rubber chemicals, sulfur dyes and oil recovery. Along with its hydrate form, sodium sulfide releases hydrogen...
Approved
Matched Description: … However the clinical significance and mechanism of action of sodium sulfide and replication of results ... been investigated in models of inflammation and oxidative stress. ... treatment, textile industry, and various chemical manufacturing processes including the production of …
Flucloxacillin
Antibiotic analog of cloxacillin.
Approved
Investigational
Matched Description: … Antibiotic analog of [cloxacillin]. …
Matched Categories: … combinations of penicillins …
Matched Categories: … combinations of penicillins …
Oxytetracycline
A tetracycline analog isolated from the actinomycete streptomyces rimosus and used in a wide variety of clinical conditions.
Approved
Investigational
Vet approved
Matched Description: … tetracycline analog isolated from the actinomycete streptomyces rimosus and used in a wide variety of …
Matched Categories: … combinations of tetracyclines …
Matched Categories: … combinations of tetracyclines …
Methylphenobarbital
A barbiturate that is metabolized to phenobarbital. It has been used for similar purposes, especially in epilepsy, but there is no evidence mephobarbital offers any advantage over phenobarbital.
Approved
Matched Categories: … combinations of barbiturates …
Sulfasalazine
Sulfasalazine is an anti-inflammatory drug structurally related to salicylates and other non-steroidal anti-inflammatory drugs. It is indicated for managing inflammatory diseases such as ulcerative colitis and rheumatoid arthritis (RA).[L39065, A255582] Metabolized by intestinal bacteria, sulfasalazine is broken down into mesalazine and sulfapyridine, 2 compounds that carry out the main pharmacological...
Approved
Matched Description: … [A255582] Sulfasalazine fell out of favor as the drug of choice for RA due to poorly designed clinical ... is not FDA-recommmended for treatment of Crohn's disease. ... into [mesalazine] and [sulfapyridine], 2 compounds that carry out the main pharmacological activity of …
Matched Categories: … combinations of sulfonamides …
Matched Categories: … combinations of sulfonamides …
Adalimumab
Adalimumab is a subcutaneously administered biological disease modifier for the treatment of rheumatoid arthritis and other chronic debilitating diseases mediated by tumor necrosis factor.[A39984,A39999] It was originally launched by Abbvie in the U.S. and approved in 2002 by the FDA. This drug is frequently known as Humira. It is produced...
Approved
Experimental
Matched Description: … Adalimumab is a subcutaneously administered biological disease modifier for the treatment of rheumatoid ... [L49101] A biosimilar marketed as Hyrimoz, a high-concentration formulation of adalimumab, is also available …
Minoxidil
A potent direct-acting peripheral vasodilator (vasodilator agents) that reduces peripheral resistance and produces a fall in blood pressure.
Approved
Investigational
Matched Mixtures name: … MINOXIDIL 7% / NIACINAMIDE 4% s …
Chlorzoxazone
A centrally acting central muscle relaxant with sedative properties. It is claimed to inhibit muscle spasm by exerting an effect primarily at the level of the spinal cord and subcortical areas of the brain. (From Martindale, The Extra Pharmacopoea, 30th ed, p1202)
Approved
Matched International brands: … Remular-S …
Matched Description: … and subcortical areas of the brain. ... It is claimed to inhibit muscle spasm by exerting an effect primarily at the level of the spinal cord …
Matched Description: … and subcortical areas of the brain. ... It is claimed to inhibit muscle spasm by exerting an effect primarily at the level of the spinal cord …
Nafcillin
A semi-synthetic antibiotic related to penicillin, Naficillin is a narrow-spectrum beta-lactam antibiotic drug. It is a beta-lactamase-resistant penicillin that is indicated for the treatment of Staphylococcal infections caused by strains that are resistant to other penicillins, except those caused by MRSA. It may be used as a first-line therapy in...
Approved
Investigational
Matched Description: … It is a beta-lactamase-resistant penicillin that is indicated for the treatment of Staphylococcal infections …
Matched Categories: … combinations of penicillins …
Matched Categories: … combinations of penicillins …
Methyltestosterone
A synthetic anabolic steroid used for treating men with testosterone deficiency or similar androgen replacement therapies. Also, has antineoplastic properties and so has been used secondarily in women with advanced breast cancer. Methyltestosterone is a schedule III drug in the US.
Approved
Matched Categories: … Sex Hormones and Modulators of the Genital System …
Amoxapine
Amoxapine, the N-demethylated derivative of the antipsychotic agent loxapine, is a dibenzoxazepine-derivative tricyclic antidepressant (TCA). TCAs are structurally similar to phenothiazines. They contain a tricyclic ring system with an alkyl amine substituent on the central ring. In non-depressed individuals, amoxapine does not affect mood or arousal, but may cause sedation....
Approved
Matched Description: … TCAs are potent inhibitors of serotonin and norepinephrine reuptake. ... See toxicity section below for a complete listing of side effects. ... Amoxapine, the N-demethylated derivative of the antipsychotic agent loxapine, is a dibenzoxazepine-derivative …
Matched Categories: … Combined Inhibitors of Serotonin/Norepinephrine Reuptake ... Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …
Matched Categories: … Combined Inhibitors of Serotonin/Norepinephrine Reuptake ... Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …
Wormwood
Wormwood is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Approved
Experimental
Displaying drugs 301 - 325 of 10489 in total