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Displaying drugs 326 - 350 of 2625 in total
Demplatin pegraglumer is under investigation in clinical trial NCT02043288 (Combination Therapy With NC-6004 and Gemcitabine Versus Gemcitabine Alone in Pancreatic Cancer).
Investigational
Matched Synonyms: … A micelle drug formulation composed of cisplatin and mPEG-poly(l-Glu) diblock copolymer with 1,3-propanediyl …
Matched Description: … pegraglumer is under investigation in clinical trial NCT02043288 (Combination Therapy With NC-6004 and
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids, Acidic ... Amino Acids ... Amino Acids, Dicarboxylic …
Pentetic acid, also known as diethylenetriaminepentaacetic acid (DTPA), is a synthetic polyamino carboxylic acid with eight coordinate bond forming sites that can sequester metal ions and form highly stable DTPA-metal ion complexes. DTPA, along with its calcium and zinc trisodium salts, are the only FDA approved agents for the treatment...
Approved
Matched Synonyms: … Pentetic acid ... Diethylene triamine pentaacetic acid ... Diethylenetriamine pentaacetic acid
Matched Name: … Pentetic acid
Matched Iupac: … 2-[bis({2-[bis(carboxymethyl)amino]ethyl})amino]acetic acid
Matched Description: … DTPA, along with its calcium and zinc trisodium salts, are the only FDA approved agents for the treatment ... acid with eight coordinate bond forming sites that can sequester metal ions and form highly stable DTPA-metal ... [L2242] DPTA was developed by the pharmaceutical company CIS US and FDA approved on April 14, 2004. …
Matched Salts name: … Pentetate calcium trisodium …
Matched Categories: … Acids, Acyclic ... Carboxylic Acids ... Lead Chelator ... Lead Chelating Activity …
Matched Products: … Pentetic Acid ... Pentetate Calcium Trisodium ... Pentetate calcium trisodium …
Zoledronic acid, or CGP 42'446, is a third generation, nitrogen containing bisphosphonate similar to ibandronic acid, minodronic acid, and risedronic acid. Zoledronic acid is used to treat and prevent multiple forms of osteoporosis, hypercalcemia of malignancy, multiple myeloma, bone metastases from solid tumors, and Paget’s disease of bone.[L13712,L13715,L13721] Zoledronic acid...
Approved
Matched Synonyms: … Zoledronic acid ... Anhydrous Zoledronic Acid ... Zoledronic Acid Anhydrous …
Matched Name: … Zoledronic acid
Matched Iupac: … [1-hydroxy-2-(1H-imidazol-1-yl)-1-phosphonoethyl]phosphonic acid
Matched Description: … to [ibandronic acid], [minodronic acid], and [risedronic acid]. ... [A203111] Zoledronic acid is used to treat and prevent multiple forms of osteoporosis, hypercalcemia ... of malignancy, multiple myeloma, bone metastases from solid tumors, and Paget’s disease of bone. …
Matched Salts name: … Zoledronic acid monohydrate ... Zoledronic acid hemipentahydrate …
Matched Categories: … zoledronic acid, calcium and colecalciferol, sequential ... Drugs Affecting Bone Structure and Mineralization ... zoledronic acid
Matched Products: … Zoledronic acid ... Zoledronic Acid ... ACIDO ZOLEDRONICO SUN …
Olopatadine is a selective histamine H1 antagonist and mast cell stabilizer that works by attenuating inflammatory and allergic reactions. It is a structural analog of doxepin, which has a minimal anti-allergic activity. Olopatadine works by blocking the effects of histamine, which is a primary inflammatory mediator that causes inflammatory and...
Approved
Matched Iupac: … dimethylamino)propylidene]-9-oxatricyclo[9.4.0.0^{3,8}]pentadeca-1(15),3(8),4,6,11,13-hexaen-5-yl]acetic acid
Matched Description: … inflammatory and allergic reactions. ... seasonal and perennial allergic conjunctivitis in 1996 and 2002, respectively. ... Olopatadine is a selective histamine H1 antagonist and mast cell stabilizer that works by attenuating …
Matched Categories: … Decongestants and Antiallergics …
Matched Products: … Eye Allergy Itch and Redness Relief ... Eye Allergy Itch and Redness Relief Twice Daily Relief …
Phenazopyridine, also known as Pyridium, is a urinary tract analgesic used for the short-term management of urinary tract irritation and its associated unpleasant symptoms such as burning and pain during urination. In the USA, this drug was previously marked by Roche but has been discontinued by the FDA. It is...
Approved
Matched Description: … its associated unpleasant symptoms such as burning and pain during urination. ... Pyridium, is a urinary tract analgesic used for the short-term management of urinary tract irritation and
Matched Mixtures name: … Phenazopyridine Hydrochloride, Hyoscyamine Hydrobromide, and Butabarbital …
Matched Categories: … Antipruritics and Local Anesthetics ... Genito Urinary System and Sex Hormones …
Matched Products: … Foster and Thrive Maximum Strength Urinary Pain Relief ... Foster and Thrive Neighbor Pharmacy Urinary Pain Relief …
Tranexamic acid is a synthetic derivative of lysine used as an antifibrinolytic in the treatment and prevention of major bleeding. It possesses a similar mechanism of action to aminocaproic acid but is approximately 10-fold more potent. It was first patented in 1957 and received its initial US approval in 1986.
Approved
Matched Synonyms: … Tranexmic acid ... Tranexamic acid ... Acide tranéxamique …
Matched Name: … Tranexamic acid
Matched Iupac: … (1r,4r)-4-(aminomethyl)cyclohexane-1-carboxylic acid
Matched Description: … Tranexamic acid is a synthetic derivative of [lysine] used as an antifibrinolytic in the treatment and ... [L31883] It was first patented in 1957[A230108] and received its initial US approval in 1986. ... It possesses a similar mechanism of action to [aminocaproic acid] but is approximately 10-fold more potent …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Blood and Blood Forming Organs ... Amino Acids ... Acids, Carbocyclic ... Carboxylic Acids
Matched Products: … Tranexamic acid ... Tranexamic Acid ... TRANEXAMIC ACID
Trichloroacetate, or trichloroacetic acid, is a strong acid prepared by the reaction of chlorine with acetic acid in the presence of a suitable catalyst. In clinical chemistry and biochemistry, it is used as a precipitant of macromolecules including proteins, DNA and RNA. Trichloroacetate is also found in cosmetic treatments and...
Approved
Matched Description: … , DNA and RNA. ... In clinical chemistry and biochemistry, it is used as a precipitant of macromolecules including proteins ... Trichloroacetate is also found in cosmetic treatments and topical formulations as a cauterant, which …
Matched Salts name: … Trichloroacetic acid
Matched Categories: … Acids, Acyclic ... Carboxylic Acids ... Trichloroacetic Acid
Matched Products: … Trichloroacetic Acid 30% ... Trichloroacetic Acid 15% ... Trichloroacetic Acid 5% …
Panthenol is an alcohol derivative of pantothenic acid, a component of the B complex vitamins and an essential component of a normally functioning epithelium. Panthenol exists as a racemic mixture containing both the dextrorotatory form (dexpanthenol) and the levorotatory form (levopanthenol). While pantothenic acid is optically active, only the dextrorotatory...
Approved
Matched Description: … Panthenol is an alcohol derivative of pantothenic acid, a component of the B complex vitamins and an ... Panthenol exists as a racemic mixture containing both the dextrorotatory form (dexpanthenol) and the ... Due to its good penetration and high local concentrations, dexpanthanol is used in many topical products …
Matched Mixtures name: … Therapytion Nokmosu Sensitive and Dry Hair ... Therapytion Nokmosu Neutral and oily Hair …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids
Matched Products: … BABOR Baborganic Calm and Relax …
Menthol is a covalent organic compound made synthetically or obtained from peppermint or other mint oils. Forming clear or white waxy, crystalline substance, menthol is typically solid at room temperature. (-)-Menthol is the naturally-occurring and main form of menthol, and is assigned the (1R,2S,5R) configuration. Menthol mediates anesthetic properties and...
Approved
Matched Description: … . (-)-Menthol is the naturally-occurring and main form of menthol, and is assigned the (1R,2S,5R) configuration ... Menthol mediates anesthetic properties and anti-irritating properties locally, thus it is widely used …
Matched Mixtures name: … Half and Half Balm ... Jack and Jill Rub ... Satohap Cool and Hot Pads …
Matched Categories: … Calcium Channel Blockers ... Basic Lotions and Liniments ... Antipruritics and Local Anesthetics ... Herbs and Natural Products ... Other Cold and Cough Preparations …
Matched Products: … Musle and Joint ... Performance and Recovery …
Atidarsagene autotemcel, sold under the brand name Libmeldy, is a gene therapy comprising genetically modified autologous CD34+ enriched hematopoietic stem and progenitor cells transduced ex vivo using a lentiviral vector encoding the human arylsulfatase A (ARSA) gene. Libmeldy was granted orphan designation by the EMA in April 2007, and was...
Approved
Matched Synonyms: … Autologous CD34+ cell enriched population that contains haematopoietic stem and progenitor cells (HSPC ... transduced with lentiviral vector which encodes for the aryl Sulfatase A complimentary deoxyribonucleic acid
Matched Description: … Libmeldy, is a gene therapy comprising genetically modified autologous CD34+ enriched hematopoietic stem and ... [L45191] Libmeldy was granted orphan designation by the EMA in April 2007, and was issued a marketing …
Matched Categories: … Alimentary Tract and Metabolism ... Enzymes and Coenzymes …
Investigational
Matched Synonyms: … CD4+ CD8+ T CELLS ARE DERIVED FROM ISOLATED BLOOD OF THE PATIENT AND ARE TRANSDUCED WITH NON-REPLICATIVE …
Investigational
Matched Synonyms: … AUTOLOGOUS CD4+ AND CD8+ T CELLS, ENRICHED FROM PERIPHERAL BLOOD MONONUCLEAR CELLS (PBMCS) TRANSDUCED …
Levoleucovorin is the enantiomerically active form of Folinic Acid (also known as 5-formyl tetrahydrofolic acid or leucovorin). Commercially available leucovorin is composed of a 1:1 racemic mixture of the dextrorotary and levorotary isomers, while levoleucovorin contains only the pharmacologically active levo-isomer. In vitro, the levo-isomer has been shown to be...
Approved
Investigational
Matched Synonyms: … L-Folinic acid ... (6S)-Folinic acid ... Levofolinic acid
Matched Iupac: … -amino-5-formyl-4-oxo-1,4,5,6,7,8-hexahydropteridin-6-yl]methyl}amino)phenyl]formamido}pentanedioic acid
Matched Description: … This important pathway, which is required for de novo synthesis of nucleic acids and amino acids, is ... and methionine before incorporation into DNA or protein. ... acid or leucovorin). …
Matched Salts name: … Levoleucovorin calcium ... Levoleucovorin calcium pentahydrate …
Matched Categories: … Folic Acid and Derivatives ... Enzymes and Coenzymes ... Folic Acid Analogues ... calcium levofolinate ... Leucovorin Calcium-Levoleucovorin …
Matched Products: … Levoleucovorin Calcium ... CALCIO LEVOFOLINATO PENSA ... CALCIO LEVOFOLINATO HOSPIRA …
Fexofenadine is an over-the-counter second-generation antihistamine used in the treatment of various allergic symptoms. It is selective for the H1 receptor, carries little-to-no activity at off-targets, and does not cross the blood-brain barrier - this is in contrast to previous first-generation antihistamines, such as diphenhydramine, which readily bind to off-targets...
Approved
Investigational
Matched Synonyms: … Terfenadine acid metabolite ... 4-(1-Hydroxy-4-(4-(hydroxydiphenylmethyl)-1-piperidinyl)butyl)-alpha,alpha-dimethylbenzeneacetic acid
Matched Iupac: … 2-(4-{1-hydroxy-4-[4-(hydroxydiphenylmethyl)piperidin-1-yl]butyl}phenyl)-2-methylpropanoic acid
Matched Description: … L4269] It is selective for the H1 receptor, carries little-to-no activity at off-targets, and ... [A1452] Fexofenadine is the major active metabolite of [terfenadine][A1495] and is administered as a …
Matched Mixtures name: … FEXOFENADINE HCl AND PSEUDOEPHEDRINE HCl ... FEXOFENADINE HYDROCHLORIDE and PSEUDOEPHEDRINE HYDROCHLORIDE ... Allergy and Congestion …
Matched Products: … Up and Up Allergy Relief ... Berkley and Jensen Allergy Relief ... Up and Up Non Drowsy Allergy Relief …
Nogapendekin alfa is a human IL-15N72D variant. It is one of the active ingredients in Anktiva, a combination product also containing inbakicept, where a single inbakicept is complexed with two nogapendekin alfa components. This combination product was approved by the FDA on April 22, 2024, for the treatment of BCG-unresponsive...
Approved
Investigational
Matched Synonyms: … Fusion protein consisting of il-15n72d and il-15rasu/fc ... Human interleukin 15 (72-aspartic acid) (human il-15 n72>d isoform) …
Matched Description: … 75% of all bladder tumours, is commonly treated with transurethral resection of the bladder tumour and ... proliferation of natural killer cells and CD8+ memory T cells, which also synergistically enhance BCG ... Nogapendekin alfa, in combination with inbakicept, mimics the actions of IL-15, , stimulating the activation and
Matched Categories: … Amino Acids, Peptides, and Proteins …
Trolamine salicylate is an organic compound or a salt formed between triethanolamine and salicylic acid. Triethanolamine neutralizes the acidity of the salicylic acid. It is a topical analgesic used for temporary relief of minor pain associated with arthritis, simple backache, muscle strains, sprains, and bruises. Unlike other topical analgesics, trolamine...
Approved
Matched Iupac: … 2-[bis(2-hydroxyethyl)amino]ethan-1-ol; 2-hydroxybenzoic acid
Matched Description: … Trolamine salicylate is an organic compound or a salt formed between triethanolamine and salicylic acid ... Triethanolamine neutralizes the acidity of the salicylic acid. ... temporary relief of minor pain associated with arthritis, simple backache, muscle strains, sprains, and
Matched Categories: … Acids, Carbocyclic ... Hydroxy Acids ... Carboxylic Acids
Matched Products: … Up and Up Pain Relief Odorless ... Up and Up Odor-free Pain Relieving Cream …
Pectin is a heteropolysaccharide commercially derived from the cell wall of higher plants. It is composed of partially methylated polygalacturonic acid units linked in the positions 1-4. The carboxylic group of the constituents of pectin can exist in the form of esters, free acids, ammonium, potassium or sodium salts or...
Approved
Investigational
Vet approved
Matched Description: … , ammonium, potassium or sodium salts or as acid amides. ... [A32327] It is composed of partially methylated polygalacturonic acid units linked in the positions 1 ... [L1961] The carboxylic group of the constituents of pectin can exist in the form of esters, free acids
Matched Mixtures name: … Cepacol Sore Throat and Coating ... Kaolin and Pectin Susp ... Sucrets Complete Sore Throat, Cough and Irritation …
Matched Categories: … Alimentary Tract and Metabolism ... Diet, Food, and Nutrition …
Matched Products: … Ludens Honey and Berry …
evorpacept is under investigation in clinical trial NCT04755244 (A Study of Evorpacept (ALX148) With Venetoclax and Azacitidine for Acute Myeloid Leukemia (ASPEN-05)).
Investigational
Matched Synonyms: … of human signal regulatory protein alpha (SIRPalpha) variant 1 (v1) genetically linked to a modified and
Matched Description: … is under investigation in clinical trial NCT04755244 (A Study of Evorpacept (ALX148) With Venetoclax and
Matched Categories: … Amino Acids, Peptides, and Proteins …
Verpasep caltespen is a recombinant chimeric protein composed of the heat shock protein 65 (Hsp65) from Mycobacterium bovis, and the human papilloma viral (HPV) protein E7. Hsp65, similar to other members of its family of proteins, elicits a strong immune response and may be used to design vaccines against a...
Investigational
Matched Synonyms: … Recombinant fusion protein of Mycobacterium bovis BCG Hsp65 and HPV16 E7 …
Matched Description: … E7 protein is involved in carcinogenesis of anal and cervical tumors, and represents a tumor antigen ... recombinant chimeric protein composed of the heat shock protein 65 (Hsp65) from _Mycobacterium bovis_, and ... Hsp65, similar to other members of its family of proteins, elicits a strong immune response and may be …
Approved
Matched Synonyms: … D-gluconic acid, iron(2+) salt (2:1) ... Ferric Gluconate ... Ferrous gluconate anhydrous …
Matched Name: … Ferrous gluconate …
Matched Mixtures name: … Somarexin and C 1000 ... Magnum-75 Vitamin and Mineral Supplement …
Matched Salts name: … Ferrous gluconate dihydrate …
Matched Categories: … ferrous gluconate and folic acid ... Blood and Blood Forming Organs ... ferrous gluconate …
Matched Products: … Ferrous Gluconate ... FERRO COMPLEX ... Ferrous Gluconate Tab 300mg …
Ferric sulfate has the molecular formula of Fe2SO4, and it is a dark brown or yellow chemical agent with acidic properties. It is produced by the reaction of sulfuric acid and an oxidizing agent. It is used in different fields such as dermatology, dentistry and it is thought to present...
Approved
Matched Synonyms: … Ferric sulfate
Matched Name: … Ferric sulfate
Matched Description: … Ferric sulfate has the molecular formula of Fe2SO4, and it is a dark brown or yellow chemical agent with ... It is produced by the reaction of sulfuric acid and an oxidizing agent. ... [A32355, A32356] By the FDA, ferric sulfate is a direct food substance affirmed in the GRAS category …
Royal jelly is an animal extract used in some OTC (over-the-counter) products. It is not an approved drug.
Experimental
Matched Synonyms: … Honey Bee Secretion Used in the Nutrition of Larvae and Adult Queens Secreted From Worker Bee Hypopharyngeal …
Matched Mixtures name: … Shine Oramin Natural Korean Ginseng + Royal Jelly with Multivitamins and Minerals. …
Bacitracin is a combination of at least 9 bacitracins.[A955,A181952] 60-80% of commercially prepared bacitracin is bacitracin A. The bacillus that produces bacitracin was first isolated from a knee scrape in 1945 from the knee wound of a child named Margaret Tracy. Bacitracin was granted FDA approval on 29 July 1948.[A181997,L7748]
Approved
Vet approved
Matched Iupac: … heptaoxo-1,4,7,10,13,16,19-heptaazacyclopentacosan-21-yl]carbamoyl}-2-methylbutyl]carbamoyl}butanoic acid
Matched Description: … Bacitracin is a combination of at least 9 bacitracins. …
Matched Mixtures name: … Neomycin Sulfate, Polymyxin B Sulfate and Bacitracin Zinc ... Bacitracin Zinc, Neomycin Sulfate and Polymyxin B Sulfate ... Bacitracin Zinc, Neomycin Sulfate and Polymyxin B Sulfate
Matched Categories: … Amino Acids, Peptides, and Proteins ... Acids, Carbocyclic ... Hydroxy Acids ... Carboxylic Acids
Matched Products: … Up and Up First Aid Antibiotic ... Up and Up Bacitracin first aid …
Ensulizole, also known as 2-phenylbenzimidazole-5-sulfonic acid, is a water-soluble sunscreen agent that absorbs strongly at UV-B wavelengths. It is commonly found in cosmetic products and sunscreen formulas in combination with other UV filter compounds due to its minimal protection against UV-A wavelengths. Due to its water solubility, ensulizole is commonly...
Approved
Matched Synonyms: … phenylbenzimidazole sulfonic acid
Matched Iupac: … 2-phenyl-1H-1,3-benzodiazole-6-sulfonic acid
Matched Description: … Due to its water solubility, ensulizole is commonly used in products formulated to feel light and less ... It is commonly found in cosmetic products and sunscreen formulas in combination with other UV filter ... the maximal approved concentration of ensulizole is 148 mM although concentrations ranging between 74 and
Matched Mixtures name: … Polyglutamic Acid Dewy Sunscreen SPF 30 ... Octinoxate,octisalate,avobenzone,octocrylene,ensulizole,titanium Dioxide ... Octisalate,octocrylene,octinoxate,zinc Oxide,titanium Dioxide,ensulizole …
Matched Categories: … Acids ... Sulfur Acids ... Acids, Noncarboxylic …
Matched Products: … Dolce and Gabbana The Foundation Perfect Matte Broadspectrum SPF 20 All shades ... Lancome Paris Teint Idole Ultra Care and Glow Skincare Foundation Broad Spectrum SPF 27 Sunscreen …
Fluticasone propionate is a synthetic glucocorticoid[F4355,F4358][FDA Label]. These drugs are available as inhalers, nasal, sprays, and topical treatments for various inflammatory indications[F4355,F4358][FDA Label]. Fluticasone propionate was first approved in 1990 .
Approved
Matched Description: … These drugs are available as inhalers, nasal, sprays, and topical treatments for various inflammatory …
Matched Mixtures name: … Fluticasone Propionate and Salmeterol ... Fluticasone Propionate and Salmeterol ... Fluticasone Propionate and Salmeterol …
Matched Products: … Up and Up Allergy Relief Nasal ... Up and Up allergy relief nasal ... Berkley and Jensen Allergy Relief …
Displaying drugs 326 - 350 of 2625 in total