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Displaying drugs 351 - 375 of 14945 in total

Pramocaine

Pramocaine (also known as pramoxine or pramoxine HCI) is a topical anesthetic and antipruritic. It is used for many dermatological and anorectal/anogenital conditions including minor cuts/burns, insect bites, hives/rashes due to poison ivy exposure, hemorrhoids and other anorectal/anogenital disorders. Pramocaine is available by itself and in combination with other medications...
Approved
Matched Description: … Pramocaine (also known as pramoxine or pramoxine HCI) is a topical anesthetic and antipruritic. ... bites, hives/rashes due to poison ivy exposure, hemorrhoids and other anorectal/anogenital disorders ... It is used for many dermatological and anorectal/anogenital conditions including minor cuts/burns, insect …
Matched Mixtures name: … Bite and Itch ... Up and Up Hemorrhoidal ... Antibiotic, Pain and Scar …
Matched Categories: … Antipruritics and Local Anesthetics ... Agents for Treatment of Hemorrhoids and Anal Fissures for Topical Use …

Rasburicase

Rasburicase is a recombinant urate-oxidase enzyme produced by a genetically modified Saccharomyces cerevisiae strain. The cDNA coding for rasburicase was cloned from a strain of Aspergillus flavus.
Approved
Investigational
Matched Categories: … Enzymes and Coenzymes ... Uric Acid-specific Enzyme …

Liothyronine

Liothyronine is a thyroidal hormone T3 which is normally produced by the thyroid gland in a ratio 4:1 when compared with T4: T3. Liothyronine is the active form of thyroxine which is composed in a basic chemical structure by a tyrosine with bound iodine. The exogenous liothyronine product was developed...
Approved
Vet approved
Matched Iupac: … (2S)-2-amino-3-[4-(4-hydroxy-3-iodophenoxy)-3,5-diiodophenyl]propanoic acid …
Matched Description: … [T457] The exogenous liothyronine product was developed by King Pharmaceuticals and FDA approved in 1956 …
Matched Mixtures name: … Levothyroxine and Liothyronine Thyroid ... Levothyroxine and Liothyronine Thyroid ... Levothyroxine and Liothyronine Thyroid …
Matched Categories: … Sex Hormones and Insulins ... combinations of levothyroxine and liothyronine ... Hormones, Hormone Substitutes, and Hormone Antagonists …

Homosalate

Homosalate is an organic compound that belongs to salicylates. It is an ester formed from salicylic acid and 3,3,5-trimethylcyclohexanol, a derivative of cyclohexanol. Salicylates prevent direct skin exposure to the sun’s harmful rays by absorbing ultraviolet (UV) light. Homosalate specifically absorbs short-wave UVB rays, which are associated with DNA damage...
Approved
Investigational
Matched Description: … It is an ester formed from salicylic acid and 3,3,5-trimethylcyclohexanol, a derivative of cyclohexanol ... Homosalate specifically absorbs short-wave UVB rays, which are associated with DNA damage and increased …
Matched Mixtures name: … HEB SPF 50 Hydrate 50 Sunscreen with Hyaluronic Acid and Collagen Continuous Sunscreen ... HYALURONIC ACID WATERY SUN gel ... Hyalu-melon With Conditioning (hyaluronic Acid + Watermelon) …

Chromic chloride

Chromic chloride, for injection, is a sterile, nonpyrogenic solution intended for use as an additive to solutions for Total Parenteral Nutrition (TPN).
Approved
Matched Mixtures name: … Palm Springs Multvit and Min Tab ... Multiple Vitamins and Minerals ... Multivitamins and Minerals Tablets …

Cycloguanil

Cycloguanil is the active metabolite of proguanil.
Approved
Matched Categories: … Folic Acid Antagonists ... Antiparasitic Products, Insecticides and Repellents …

Nadolol

Nadolol is a nonselective beta adrenal receptor blocker that is used to lower blood pressure.[L7922,L7925] Nonselective beta adrenal receptor blockers may no longer be first line in the treatment of hypertension as newer generations of beta adrenal receptor blockers have higher selectivity and offer better rates of adverse effects. Nadolol...
Approved
Matched Description: … treatment of hypertension as newer generations of beta adrenal receptor blockers have higher selectivity and …
Matched Mixtures name: … Nadolol and Bendroflumethiazide ... Nadolol and Bendroflumethiazide ... Nadolol and Bendroflumethiazide …
Matched Categories: … nadolol and thiazides ... Beta Blocking Agents and Thiazides ... Beta Blocking Agents, Non-Selective, and Thiazides …

Propranolol

Propranolol is a racemic mixture of 2 enantiomers where the S(-)-enantiomer has approximately 100 times the binding affinity for beta adrenergic receptors. Propranolol is used to treat a number of conditions but most commonly is used for hypertension.[L6901,L6904,L6907] Propranolol was granted FDA approval on 13 November 1967.
Approved
Investigational
Matched Mixtures name: … Propranolol Hydrochloride and Hydrochlorothiazide ... Propranolol Hydrochloride and Hydrochlorothiazide ... Propranolol Hydrochloride and Hydrochlorothiazide …
Matched Categories: … propranolol and thiazides ... Beta Blocking Agents and Thiazides ... propranolol and other combinations ... Beta Blocking Agents, Non-Selective, and Thiazides …

Pregnenolone

A 21-carbon steroid, derived from cholesterol and found in steroid hormone-producing tissues. Pregnenolone is the precursor to gonadal steroid hormones and the adrenal corticosteroids.
Approved
Experimental
Matched Description: … A 21-carbon steroid, derived from cholesterol and found in steroid hormone-producing tissues. ... Pregnenolone is the precursor to gonadal steroid hormones and the adrenal corticosteroids. …
Matched Categories: … Hormones, Hormone Substitutes, and Hormone Antagonists …

Sebelipase alfa

The lysosomal acid lipase (LAL) enzyme is found in lysosomes and is primarily responsible for the metabolism of lipids, and its absence or deficiency results in the accumulation of lipids in various organs. This lipid accumulation can lead to end-organ damage in the form of liver dysfunction or malabsorption secondary...
Approved
Investigational
Matched Description: … The lysosomal acid lipase (LAL) enzyme is found in lysosomes and is primarily responsible for the metabolism ... It was first approved by both the FDA and EMA in 2015 and is marketed under the brand name Kanuma (Alexion ... of lipids, and its absence or deficiency results in the accumulation of lipids in various organs. …
Matched Categories: … Enzymes and Coenzymes ... Alimentary Tract and Metabolism …

Olipudase alfa

Olipudase alfa is recombinant human acid sphingomyelinase. It is the first and only enzyme replacement therapy in the world for the treatment of Acid Sphingomyelinase Deficiency (ASMD), also known as Niemann–Pick disease. ASMD is a rare lysosomal storage disease caused by mutations in the SMPD1 gene, leading to a deficiency...
Approved
Investigational
Matched Description: … [A251590] It is the first and only enzyme replacement therapy in the world for the treatment of Acid ... Olipudase alfa is recombinant human acid sphingomyelinase. ... a rare lysosomal storage disease caused by mutations in the SMPD1 gene, leading to a deficiency in acid …
Matched Categories: … Enzymes and Coenzymes ... Alimentary Tract and Metabolism ... Amino Acids, Peptides, and Proteins …

Tamsulosin

Tamsulosin is a selective alpha-1A and alpha-1B adrenoceptor antagonist that exerts its greatest effect in the prostate and bladder, where these receptors are most common.[Label] It is indicated for the treatment of signs and symptoms of benign prostatic hypertrophy.[Label] Antagonism of these receptors leads to relaxation of smooth muscle in...
Approved
Investigational
Matched Description: … in the prostate and bladder, where these receptors are most common. ... Tamsulosin is a selective alpha-1A and alpha-1B adrenoceptor antagonist that exerts its greatest effect ... [Label] It is indicated for the treatment of signs and symptoms of benign prostatic hypertrophy. …
Matched Mixtures name: … Dutasteride and tamsulosin hydrochloride ... Dutasteride and Tamsulosin Hydrochloride ... Dutasteride and tamsulosin hydrochloride …
Matched Categories: … tamsulosin and tadalafil ... tamsulosin and dutasteride ... tamsulosin and solifenacin ... Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics …

Eladocagene exuparvovec

Eladocagene exuparvovec is a recombinant adeno-associated virus-2 (AAV2)-based gene therapy that expresses human aromatic L-amino acid decarboxylase (AADC), and it is used to treat AADC deficiency, a fatal and rare genetic disorder that causes severe disability in pediatric patients.[L43642,L43672] Patients with AADC have mutations in the dopa decarboxylase (DDC) gene...
Approved
Investigational
Matched Description: … recombinant adeno-associated virus-2 (AAV2)-based gene therapy that expresses human aromatic L-amino acid ... decarboxylase (AADC), and it is used to treat AADC deficiency, a fatal and rare genetic disorder that ... neurotransmitter production, decrease neurotransmitter catabolism via monoamine oxidase (MAO) inhibition and …

Silicon

Silicon is under investigation in clinical trial NCT00103246 (Photodynamic Therapy Using Silicon Phthalocyanine 4 in Treating Patients With Actinic Keratosis, Bowen's Disease, Skin Cancer, or Stage I or Stage II Mycosis Fungoides).
Approved
Investigational
Matched Mixtures name: … Multivitamins and Minerals Tablets ... Rocky Mountain Multiple Vit and Min Mega Tab ... Calcium With Mg Zn Mn Cu CR Si and Vit. C & D …
Matched Categories: … Diet, Food, and Nutrition …

Pentagastrin

A synthetic pentapeptide that mimics the actions of endogenous gastrin when given parenterally. It works by stimulating the secretion of gastric acid, pepsin, and intrinsic factor. It has also been used as a diagnostic aid.
Approved
Matched Iupac: … yl)propanamido]-4-(methylsulfanyl)butanamido]-3-{[(1S)-1-carbamoyl-2-phenylethyl]carbamoyl}propanoic acid …
Matched Description: … It works by stimulating the secretion of gastric acid, pepsin, and intrinsic factor. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Hormones, Hormone Substitutes, and Hormone Antagonists …

Naphazoline

Naphazoline is a rapid acting imidazoline sympathomimetic vasoconstrictor of ocular or nasal artierioles[L5804,L5807]. It acts to decrease congestion and is found in many over the counter (OTC) eye drops and nasal preparations[L5804,L5807]. Naphazoline was first developed in 1942 as a nasal formulation for congestion .
Approved
Investigational
Matched Description: … It acts to decrease congestion and is found in many over the counter (OTC) eye drops and nasal preparations …
Matched Mixtures name: … Lubricant and Redness Reliever ... Eye Drops Redness and Dry Eye Relief ... Eye Drops Redness and Dry Eye Relief …
Matched Categories: … Decongestants and Antiallergics …

Equus caballus hair

Horse hair is used in allergenic testing.
Approved
Matched Mixtures name: … Horse Hair and Dander ... Animal Allergens, AP Horse Hair and Dander ... Animal Allergens, AP Horse Hair and Dander …

Ritonavir

Ritonavir is an HIV protease inhibitor that interferes with the reproductive cycle of HIV. Although it was initially developed as an independent antiviral agent, it has been shown to possess advantageous properties in combination regimens with low-dose ritonavir and other protease inhibitors. It is now more commonly used as a...
Approved
Investigational
Matched Description: … formulations and as capsules. ... - and Health Canada-approved product Technivie. ... protease inhibitors such as [DB09297] and overall drug exposure. …
Matched Mixtures name: … Lopinavir and Ritonavir ... Lopinavir and ritonavir ... Lopinavir and ritonavir …
Matched Categories: … lopinavir and ritonavir ... darunavir and ritonavir ... atazanavir and ritonavir ... nirmatrelvir and ritonavir ... ombitasvir, paritaprevir and ritonavir …

Bos taurus dander

Bos taurus dander allergenic extract is used in allergenic testing.
Approved
Matched Mixtures name: … Animal Allergens, AP Cattle Hair and Dander ... Animal Allergens, AP Cattle Hair and Dander ... Animal Allergens, AP Cattle Hair and Dander …

Pegloticase

Pegloticase is a porcine recombinant PEGylated uricase indicated for the treatment of chronic gout in adult patients that do not respond to other types of therapies. Pegloticase has a similar activity to rasburicase, an enzyme that metabolizes uric acid to allantoin. In gout patients treated with pegloticase, the conversion of...
Approved
Investigational
Matched Description: … uric acid concentrations. ... of pegloticase and methotrexate. ... In gout patients treated with pegloticase, the conversion of uric acid to allantoin leads to lower plasma …
Matched Categories: … Enzymes and Coenzymes ... Uric Acid-specific Enzyme …

Corynebacterium diphtheriae toxoid antigen (formaldehyde inactivated)

Approved
Investigational
Matched Mixtures name: … Diphtheria and Tetanus Toxoids Adsorbed ... Tetanus and Diphtheria Toxoids Adsorbed ... Tetanus and Diphtheria Toxoids Adsorbed …

Mecobalamin

Approved
Investigational
Matched Mixtures name: … Levomefolate Calcium Acetylcysteine and Mecobalamin Algal ... Levomefolate Calcium, Acetylcysteine, Mecobalamin and Algal ... Levomefolate Calcium, Pyridoxal 5-phosphate, Methylcobalamin and Schizochytrium DHA Oil …
Matched Categories: … Vitamin B12 and Folic Acid ... Blood and Blood Forming Organs …

Sodium phosphate, monobasic, unspecified form

Approved
Matched Mixtures name: … Up and Up Ready To Use Enema ... Pure and Gentle Laxative ... Foster and Thrive Ready to Use Saline Laxative …

Inosine pranobex

Inosine pranobex (Isoprinosine or Methisoprinol) is a combination of inosine, acetamidobenzoic acid, and dimethylaminoisopropanol used as an antiviral drug.
Approved
Matched Iupac: … tris((2R)-1-(dimethylamino)propan-2-ol); tris(4-acetamidobenzoic acid); 9-[(2R,3R,4S,5R)-3,4-dihydroxy …
Matched Description: … and dimethylaminoisopropanol used as an antiviral drug. ... Inosine pranobex (Isoprinosine or Methisoprinol) is a combination of inosine, acetamidobenzoic acid, …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …

Canis lupus familiaris hair

Domestic dog hair is used in allergenic testing.
Approved
Matched Mixtures name: … Dog Hair and Epithelia ... Animal Allergens, Dog Hair and Dander Canis spp. ... Animal Allergens, Dog Hair and Dander Canis spp. …
Displaying drugs 351 - 375 of 14945 in total